TRANSDERMAL DELIVERY SYSTEM
    51.
    发明申请
    TRANSDERMAL DELIVERY SYSTEM 审中-公开
    超传送系统

    公开(公告)号:WO2004019920A1

    公开(公告)日:2004-03-11

    申请号:PCT/IB2002/003449

    申请日:2002-08-27

    IPC分类号: A61K9/70

    摘要: This Transdermal Delivery System (TDS) is a 'bead-on-adhesive' invention, with essential features as follows: 1) 'Bead-on-adhesive' -Encapsulated core actives which can be natural therapeutic substances, herbal prescriptions, or botanical extracts, or appropriate drugs form 'bead' which performs a template function, 2) A technique that enables a full range of production scale, from small batches for customized individual conditions to over-the-counter mass production for common aliments, 3) Controlled release transdermal delivery, 4) Masking of odor or color that core substances may have, 5) Resilient support function, 6) Self-sealant without any auxiliary fixing device. This TDS is a resilient supporting substrate, e.g. textiles, elastomers etc., [1a3, 1b2] with a self-sealant adhesive coated [1a3, 1b2] on its whole surface. Beads, which are embedded with controlled release encapsulated core actives, are either stuck at the foremost tip end surface as a 'compress' for the wrapping model or on the wrong-side [1b2] central zone [1b1] for the tubing model. Core actives are customized natural prescriptions, like Chinese herbal prescriptions, aromatherapy blends, vegetable oil blends or botanical extracts, or drugs to treat individual conditions or to heal common aliments. The encapsulated beads [1a2, 1b1], in which the core actives are embedded, are shelled with a membrane. With the membrane, all undesirable odor is masked and all possible residue colour-stains is avoided. (Figure 1a and b is a schematic representation of the bead-on-adhesive TDS invention.)

    摘要翻译: 这种透皮递送系统(TDS)是一种“胶粘剂”发明,其基本特征如下:1)“粘合剂” - 包封的核心活性物质,其可以是天然治疗物质,草药处方或植物提取物 或适当的药物形成进行模板功能的“珠”,2)能够从小批量定制个体条件到普通食品的非处方批量生产的全方位生产规模的技术,3)控制释放 透皮输送,4)核心物质可能具有的气味或颜色掩蔽,5)弹性支持功能,6)无密封剂,无任何辅助固定装置。 该TDS是弹性支撑衬底,例如。 纺织品,弹性体等,[1a3,1b2]在其整个表面上涂有自粘合剂粘合剂[1a3,1b2]。 嵌入有控制释放封装的核心活性物质的珠子或者作为包装模型的“压缩”或在管道模型的错误侧[1b2]中心区域[1b1]上粘附在最前端的顶端表面。 核心活性物质是定制的天然处方,如中草药处方,芳香疗法混合物,植物油混合物或植物提取物,或用于治疗个体病症或治疗常见食物的药物。 其中嵌入有核心活性物质的包封的珠粒[1a2,1b1]用膜包覆。 使用膜时,所有不希望的气味被掩蔽,并且避免了所有可能的残留色斑。 (图1a和b是粘合剂粘合剂TDS发明的示意图)

    BREAST PAD ASSEMBLY CONTAINING A SKIN BENEFIT INGREDIENT
    53.
    发明申请
    BREAST PAD ASSEMBLY CONTAINING A SKIN BENEFIT INGREDIENT 审中-公开
    包含皮肤有益成分的乳胶板组件

    公开(公告)号:WO2003047644A1

    公开(公告)日:2003-06-12

    申请号:PCT/US2002/026703

    申请日:2002-08-22

    IPC分类号: A61L15/44

    摘要: A breast pad assembly is disclosed wherein one face of the breast pad which faces the breast during use contains a composition comprising a skin benefit ingredient for improving the skin health of a woman's breast and nipple skin. In one embodiment of the invention, the skin health benefit ingredient comprises omega-3 fatty acids which can replace lipids lost from the breast and nipple during breast feeding. The omega-3 fatty acids can also be ingested by the infant to improve systemic development in the infant. In another embodiment, the skin benefit ingredient comprises omega-3 fatty acids and essential fatty acids.

    摘要翻译: 公开了一种乳房垫组件,其中在使用期间面向乳房的乳房垫的一个面包含包含用于改善女性乳房和乳头皮肤的皮肤健康的皮肤益处成分的组合物。 在本发明的一个实施方案中,皮肤健康益处成分包含ω-3脂肪酸,其可以代替在哺乳期间从乳房和乳头丢失的脂质。 ω-3脂肪酸也可以被婴儿摄入以改善婴儿的系统发育。 在另一个实施方案中,皮肤有益成分包含ω-3脂肪酸和必需脂肪酸。

    NATURAL COLOR CONCENTRATES AND ANTIMICROBIAL NUTRACEUTICAL FROM PLANTS
    60.
    发明申请
    NATURAL COLOR CONCENTRATES AND ANTIMICROBIAL NUTRACEUTICAL FROM PLANTS 审中-公开
    自然颜色浓度和植物的抗微生物营养

    公开(公告)号:WO99013889A2

    公开(公告)日:1999-03-25

    申请号:PCT/US1998/019329

    申请日:1998-09-16

    摘要: An active coloring concentrate can be prepared from the juice of cranberry and other fruits or vegetables by treating juice or homogenate with an appropriate binding matrix. Assorted ion exchange resins such as cholestyramine are effective binding matrices, but the currently preferred material is a food grade of cross-linked polyvinylpyrollidone. When appropriate binding matrices are used to concentrate active materials from cranberry, a colored solid is produced. This substance shows significant antibacterial and anti-viral properties. It can be readily consumed as a therapeutic or nutraceutical, used as a coloring agent, or it can be used topically. An additional advantage of the present method is that significant amounts of active concentrate can be produced from cranberrry presscake which is normally a waste material.

    摘要翻译: 通过用适当的结合基质处理果汁或匀浆,可以从蔓越莓和其他水果或蔬菜的汁液制备活性着色浓缩物。 各种离子交换树脂如消胆胺是有效的结合基质,但目前优选的材料是食品级的交联聚乙烯吡咯烷酮。 当使用适当的结合基质来浓缩蔓越莓的活性物质时,产生着色的固体。 该物质显示出显着的抗菌和抗病毒性质。 它可以容易地用作治疗或营养品,用作着色剂,或者可以局部使用。 本发明方法的另一个优点是可以从通常为废料的起泡滤饼生产大量的活性浓缩物。