公开(公告)号：WO2007056247A3

公开(公告)日：2009-05-07

申请号：PCT/US2006043133

申请日：2006-11-06

Applicant: MEDRAD INC ,  UBER ARTHUR E III ,  HIRSCHMAN ALAN D ,  FACHER EVAN ,  GELBLUM EUGENE A ,  GRIFFITHS DAVID M ,  RHINEHART EDWARD J ,  REILLY DAVID M ,  COWAN KEVIN P ,  CEDARHOLM PAGE ,  TUCKER BARRY L ,  TROCKI MARK ,  MISHLER DAVID ,  BARTONY HENRY E JR ,  PARKS ROBERT

Inventor： UBER ARTHUR E III ,  HIRSCHMAN ALAN D ,  FACHER EVAN ,  GELBLUM EUGENE A ,  GRIFFITHS DAVID M ,  RHINEHART EDWARD J ,  REILLY DAVID M ,  COWAN KEVIN P ,  CEDARHOLM PAGE ,  TUCKER BARRY L ,  TROCKI MARK ,  MISHLER DAVID ,  BARTONY HENRY E JR ,  PARKS ROBERT

IPC: A61M31/00 ,  B65D25/04

CPC classification number: A61J1/1443 ,  A61J1/1456 ,  A61J1/1475 ,  A61M5/142 ,  A61M5/1723 ,  A61M5/3145 ,  A61M31/005 ,  B01L3/502 ,  B01L2300/044 ,  B01L2300/0681 ,  G06F19/3468

Abstract: A system for delivering a fluid comprising cells to tissue of a patient, includes: a least a first container for holding an injection fluid in which the agent is carried; a first powered drive in operative connection with the container, the first powered drive being operable to pressurize contents of the container; a control system in operative connection with the first powered drive and operative to control the first powered drive; a fluid path in fluid connection with the container, the fluid path including a patient interface adapted to deposit the cells within tissue of the patient; a sensor system; and a communication system in connection with at least the control system and the sensor system. The communication system is adapted to provide information to the control system. The control system in adapted to transmit a control signal to at least the first powered drive based at least in part on information provided to the control system. The cells can for example be progenitor cells or stem cells.

Abstract translation: 一种用于将包含细胞的流体输送到患者的组织的系统，包括：用于保持其中携带有药剂的注射液体的至少第一容器; 与容器操作性连接的第一动力驱动器，第一动力驱动器可操作以对容器的内容物进行加压; 控制系统，其与第一动力驱动器操作连接并且可操作以控制第一动力驱动; 与容器流体连接的流体路径，流体路径包括适于将细胞沉积在患者组织内的患者界面; 传感器系统; 以及至少与控制系统和传感器系统相关的通信系统。 通信系统适于向控制系统提供信息。 控制系统适于至少部分地基于提供给控制系统的信息将控制信号发送到至少第一动力驱动器。 细胞可以例如是祖细胞或干细胞。

公开(公告)号：WO2007056247A2

公开(公告)日：2007-05-18

申请号：PCT/US2006/043133

申请日：2006-11-06

Applicant: MEDRAD, INC. ,  UBER, Arthur, E. III ,  HIRSCHMAN, Alan, D. ,  FACHER, Evan ,  GELBLUM, Eugene, A. ,  GRIFFITHS, David, M. ,  RHINEHART, Edward, J. ,  REILLY, David, M. ,  COWAN, Kevin, P. ,  CEDARHOLM, Page ,  TUCKER, Barry, L. ,  TROCKI, Mark ,  MISHLER, David ,  BARTONY, Henry, E., Jr. ,  PARKS, Robert

Inventor： UBER, Arthur, E. III ,  HIRSCHMAN, Alan, D. ,  FACHER, Evan ,  GELBLUM, Eugene, A. ,  GRIFFITHS, David, M. ,  RHINEHART, Edward, J. ,  REILLY, David, M. ,  COWAN, Kevin, P. ,  CEDARHOLM, Page ,  TUCKER, Barry, L. ,  TROCKI, Mark ,  MISHLER, David ,  BARTONY, Henry, E., Jr. ,  PARKS, Robert

IPC: G06F11/00

CPC classification number: A61J1/1443 ,  A61J1/1456 ,  A61J1/1475 ,  A61M5/142 ,  A61M5/1723 ,  A61M5/3145 ,  A61M31/005 ,  B01L3/502 ,  B01L2300/044 ,  B01L2300/0681 ,  G06F19/3468

Abstract: A system for delivering a fluid comprising cells to tissue of a patient, includes: a least a first container for holding an injection fluid in which the agent is carried; a first powered drive in operative connection with the container, the first powered drive being operable to pressurize contents of the container; a control system in operative connection with the first powered drive and operative to control the first powered drive; a fluid path in fluid connection with the container, the fluid path including a patient interface adapted to deposit the cells within tissue of the patient; a sensor system; and a communication system in connection with at least the control system and the sensor system. The communication system is adapted to provide information to the control system. The control system in adapted to transmit a control signal to at least the first powered drive based at least in part on information provided to the control system. The cells can for example be pregenitor cells or stem cells.

Abstract translation: 一种用于将包含细胞的流体输送到患者的组织的系统，包括：用于保持其中携带有药剂的注射液体的至少第一容器; 与容器操作性连接的第一动力驱动器，第一动力驱动器可操作以对容器的内容物进行加压; 控制系统，其与第一动力驱动器操作连接并且可操作以控制第一动力驱动; 与容器流体连接的流体路径，流体路径包括适于将细胞沉积在患者组织内的患者界面; 传感器系统; 以及至少与控制系统和传感器系统相关的通信系统。 通信系统适于向控制系统提供信息。 控制系统适于至少部分地基于提供给控制系统的信息将控制信号发送到至少第一动力驱动器。 细胞可以例如是祖细胞或干细胞。