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    METHOD FOR DETECTION AND DISPLAY OF EXTRAVASATION AND INFILTRATION OF FLUIDS AND SUBSTANCES IN SUBDERMAL OR INTRADERMAL TISSUE
    6.
    发明申请
    METHOD FOR DETECTION AND DISPLAY OF EXTRAVASATION AND INFILTRATION OF FLUIDS AND SUBSTANCES IN SUBDERMAL OR INTRADERMAL TISSUE 审中-公开
    用于检测和显示浸泡和渗透流体或物质的潜在或侵入性组织的方法

    公开(公告)号：WO2006074415A3

    公开(公告)日：2007-09-27

    申请号：PCT/US2006000562

    申请日：2006-01-09

    Applicant: MEDRAD INC ,  KALAFUT JOHN F ,  GRIFFITHS DAVID M ,  UBER ARTHUR E III

    Inventor： KALAFUT JOHN F ,  GRIFFITHS DAVID M ,  UBER ARTHUR E III

    IPC: A61B6/00

    CPC classification number: A61B5/0059

    Abstract: A method for the real-time visualization and detection of extravasated and or infiltrated fluid and substances, including blood, that occur near the cannulation site of an injection is described wherein illumination or transillumination with near infrared light is used to image the contrast in real-time between absorbing and nonabsorbing subdermal and intradermal structures of blood vessels and remaining surrounding tissue, foreign substances and other structures in order to establish a baseline image of the body area of interest, and any new image is monitored and compared with the baseline image to detect the extravasation and/or infiltration of fluids and substances, including blood, around a vein or artery into the subdermal or intradermal tissue.

    Abstract translation: 描述了一种用于在喷射插管部位附近发生的外渗和/或渗透的流体和物质（包括血液）的实时可视化和检测的方法，其中使用近红外光的照明或透照照射实时成像对比度， 吸收和不吸收血管和其余周围组织，异物和其他结构的皮下和皮内结构之间的时间，以建立感兴趣的身体区域的基线图像，并且监测任何新图像并与基线图像进行比较以检测 在静脉或动脉周围的流体和物质（包括血液）的外渗和/或渗透进入皮下或皮内组织。

    DELIVERY OF AGENTS TO TISSUE
    7.
    发明申请
    DELIVERY OF AGENTS TO TISSUE 审中-公开
    交付代理组织

    公开(公告)号：WO2007053779A2

    公开(公告)日：2007-05-10

    申请号：PCT/US2006/043134

    申请日：2006-11-06

    Applicant: MEDRAD, INC. ,  UBER, Arthur, E., III ,  TROMBLEY, Frederick, W., III ,  GELBLUM, Eugene, A. ,  RHINEHART, Edward, J. ,  REILLY, David, M. ,  CEDARHOLM, Page ,  COWAN, Kevin, P. ,  TROCKI, Mark ,  HIRSCHMAN, Alan, D.

    Inventor： UBER, Arthur, E., III ,  TROMBLEY, Frederick, W., III ,  GELBLUM, Eugene, A. ,  RHINEHART, Edward, J. ,  REILLY, David, M. ,  CEDARHOLM, Page ,  COWAN, Kevin, P. ,  TROCKI, Mark ,  HIRSCHMAN, Alan, D.

    IPC: A61M31/00 ,  A01N1/02 ,  C12M1/12 ,  C12M1/24 ,  B65D25/04 ,  A01N1/00 ,  C12M3/00 ,  B65D1/24

    CPC classification number: A61J1/1443 ,  A61J1/1456 ,  A61J1/1475 ,  A61M5/142 ,  A61M5/1723 ,  A61M5/3145 ,  A61M31/005 ,  B01L3/502 ,  B01L2300/044 ,  B01L2300/0681 ,  G06F19/3468

    Abstract: A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.

    Abstract translation: 用于将注射器注射到患者体内的系统包括用于保持注射器的第一可加压容器; 与所述第一可加压容器流体连接的患者接口，所述患者接口适于将所述注射器通入患者的组织; 动力注射器，其与所述第一可加压容器可操作地连接以对所述注射器加压; 与动力注射器操作连接的控制器系统; 以及适于与病人界面操作连接的立体定向定位框架，以协助控制患者界面的定位。 用于处理细胞（和/或其它注射组分）的系统​​包括适于可滑动地定位在容器内的容器和柱塞。 该系统包括至少一个入口，流体可以通过该入口进入系统和至少一个流出物端口，流出物可通过该至少一个出口端口离开系统。 柱塞部分形成与容器的内壁的密封接合，使得柱塞的向后运动适于通过入口将流体引入系统，并且柱塞的向前运动适于通过流出物强制流出系统的流出物 港口。

    ELECTRONIC CIRCUIT WITH A NON-CONTINUOUS DISCHARGE PATH
    8.
    发明申请
    ELECTRONIC CIRCUIT WITH A NON-CONTINUOUS DISCHARGE PATH 审中-公开
    具有非连续放电路径的电子电路

    公开(公告)号：WO0028337A3

    公开(公告)日：2000-11-30

    申请号：PCT/US9925745

    申请日：1999-11-05

    Applicant: ONGUARD SYSTEMS INC ,  UBER ARTHUR E III ,  ZIFF JOSHUA J ,  UBER ROBERT E

    Inventor： UBER ARTHUR E III ,  ZIFF JOSHUA J ,  UBER ROBERT E

    IPC: G01R19/00 ,  G01J1/44 ,  G01R19/25

    CPC classification number: G01R19/2509 ,  G01J1/44

    Abstract: The present invention relates to an electronic circuit and an array of such circuits for precisely measuring small amounts or small changes in the amount of charge, voltage, or electrical currents. One embodiment of the present invention provides an electronic circuit for measuring current or charge that can be used with a variety of sensing media (including high impedance sensing media) that produce a signal by either charge or current production or induction in response to physical phenomena occurring within the sensing media. In another embodiment, the voltage level (bias) of either the sensing or reference electrode can be switched relative to the other upon receipt of a triggering pulse. This changes the polarity of the electric field to cause charge of the opposite polarity to be driven to the sensing electrode, thereby eliminating the need to electrically connect a discharge path to the sensing electrode to clear the charge accumulated at the sensing electrode. Alternate preferred embodiments of the invention permit use of the invention with sensing media other than ion chambers, including piezoelectric materials, pyroelectric materials, photoelectric materials, liquid electrochemical materials, vacuum/gas/liquid/solid charge conduction materials, inductive pick-ups or coils, electric field measuring antennas, or even a surface with charge emission or work function changes.

    Abstract translation: 本发明涉及电子电路和用于精确测量电荷量，电压或电流量的少量或小的变化的这种电路的阵列。 本发明的一个实施例提供了一种用于测量电流或电荷的电子电路，其可以与各种感测介质（包括高阻抗传感介质）一起使用，所述感测介质（包括高阻抗传感介质）通过响应于物理现象产生的电荷或当前的产生或感应产生信号 在传感媒体内。 在另一个实施例中，感测或参考电极的电压电平（偏置）可以在接收到触发脉冲时相对于另一个切换。 这改变了电场的极性，使得相反极性的电荷被驱动到感测电极，从而不需要将放电路径电连接到感测电极，以清除在感测电极处积累的电荷。 本发明的替代优选实施例允许本发明与离子室以外的感测介质一起使用，包括压电材料，热电材料，光电材料，液体电化学材料，真空/气体/液体/固体电荷传导材料，感应拾取器或线圈 ，电场测量天线，甚至具有电荷发射或功能变化的表面。

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