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    DOUGH COMPRISING NUCLEOTIDE PYROPHOSPHATASE INHIBITOR
    3.
    发明申请
    DOUGH COMPRISING NUCLEOTIDE PYROPHOSPHATASE INHIBITOR 审中-公开
    包含核苷酸磷酸酯酶抑制剂

    公开(公告)号：WO2006000066A3

    公开(公告)日：2006-05-04

    申请号：PCT/BE2005000104

    申请日：2005-06-29

    申请人： PURATOS NV ,  PARMENTIER SOFIE ,  VANDAMME ERIC ,  BEAUPREZ JOERI ,  ARNAUT FILIP

    发明人： PARMENTIER SOFIE ,  VANDAMME ERIC ,  BEAUPREZ JOERI ,  ARNAUT FILIP

    IPC分类号： A21D2/02 ,  A21D8/04 ,  C12N9/14

    CPC分类号： A21D2/02 ,  A21D8/042 ,  C12N9/14

    摘要： The present invention is related to a method for inhibiting nicotinamide coenzyme degradation in a cereal flour or wheat based product, comprising the addition of an effective amount of nucleotide pyrophosphatase inhibitor to said cereal flour based product, product such as a wheat based product. A further aspect of the present invention is a nucleotide pyrophosphatase having an amino acid N-terminal sequence being (G) IDDRHEVDLPPRP. In another aspect of the present invention, a dough comprising a nucleotide pyrophosphatase inhibitor such as pyrophosphate, and optionally a coenzyme regeneration system comprising at least one NAD(P) or NAD(P)H dependent hydrogenase or dehydrogenase is disclosed. Preferably the coenzyme regeneration system comprises (consists of) mannitol dehydrogenase and D-fructose.

    摘要翻译： 本发明涉及一种抑制谷类粉或小麦基产品中烟酰胺辅酶降解的方法，包括向所述谷类粉基产品，例如小麦基产品等产品中加入有效量的核苷酸焦磷酸酶抑制剂。 本发明的另一方面是具有氨基酸N-末端序列为（G）IDDRHEVDLPPRP的核苷酸焦磷酸酶。 在本发明的另一方面，公开了一种包含核苷酸焦磷酸酶抑制剂如焦磷酸盐的面团，以及任选地包含至少一种NAD（P）或NAD（P）H依赖性氢化酶或脱氢酶的辅酶再生系统。 优选地，辅酶再生系统包含（由甘露糖醇脱氢酶和D-果糖组成）。

    BACTERIAL MUTANTS AND USES THEREOF IN PROTEIN PRODUCTION
    5.
    发明申请
    BACTERIAL MUTANTS AND USES THEREOF IN PROTEIN PRODUCTION 审中-公开
    细菌菌株及其在蛋白质生产中的应用

    公开(公告)号：WO2011083059A1

    公开(公告)日：2011-07-14

    申请号：PCT/EP2010/070683

    申请日：2010-12-23

    申请人： UNIVERSITEIT GENT ,  BEAUPREZ, Joeri

    发明人： BEAUPREZ, Joeri

    IPC分类号： C07K14/245 ,  C12N15/70 ,  C12P21/02

    CPC分类号： C12N15/70 ,  C12P21/02

    摘要： The present invention relates to a method for obtaining increased product yields and/or for eliminating by-product formation in micro-organisms, and to mutants and/or transformants for use in said methods. More particularly, it relates to bacterial mutants and/or transformants that are affected in the primary metabolism for enhanced product formation, for enhanced product yield and/or for eliminating production of by-products, especially mutants and/or transformants that are affected in the repression of the glyoxylate bypass and in the chromosomal gene expression in response to deprivation of oxygen or in response to absence/presence of carbon compounds such as glycerol, fatty acids, glyoxylate, acetate and the like.

    摘要翻译： 本发明涉及一种用于获得增加的产物产率和/或消除微生物中副产物形成的方法，以及用于所述方法的突变体和/或转化体。 更具体地说，它涉及在初级代谢中受影响以增强产物形成，提高产物产量和/或用于消除副产物，特别是受影响的突变体和/或转化体的产生的细菌突变体和/或转化体。 乙醛酸酯旁路的抑制和染色体基因表达响应于剥夺氧或响应于碳化合物如甘油，脂肪酸，乙醛酸盐，乙酸盐等的存在/存在。

    NUCLEOTIDE PYROPHOSPHATASE INHIBITOR AND COENZYME REGENERATING SYSTEMS
    7.
    发明申请
    NUCLEOTIDE PYROPHOSPHATASE INHIBITOR AND COENZYME REGENERATING SYSTEMS 审中-公开
    核苷酸磷酸酯酶抑制剂和重组体系统

    公开(公告)号：WO2006000066A2

    公开(公告)日：2006-01-05

    申请号：PCT/BE2005/000104

    申请日：2005-06-29

    申请人： PURATOS Naamloze Vennootschap ,  PARMENTIER, Sofie ,  VANDAMME, Eric ,  BEAUPREZ, Joeri ,  ARNAUT, Filip

    发明人： PARMENTIER, Sofie ,  VANDAMME, Eric ,  BEAUPREZ, Joeri ,  ARNAUT, Filip

    IPC分类号： A21D2/02 ,  A21D8/04

    CPC分类号： A21D2/02 ,  A21D8/042 ,  C12N9/14

    摘要： The present invention is related to a method for inhibiting nicotinamide coenzyme degradation in a cereal flour or wheat based product, comprising the addition of an effective amount of nucleotide pyrophosphatase inhibitor to said cereal flour based product, product such as a wheat based product. A further aspect of the present invention is a nucleotide pyrophosphatase having an amino acid N-terminal sequence being (G)IDDRHEVDLPPRP. In another aspect of the present invention, a dough comprising a nucleotide pyrophosphatase inhibitor such as pyrophosphate, and optionally a coenzyme regeneration system comprising at least one NAD(P) or NAD(P)H dependent hydrogenase or dehydrogenase is disclosed. Preferably the coenzyme regeneration system comprises (consists of) mannitol dehydrogenase and D-fructose.

    摘要翻译： 本发明涉及一种抑制谷类粉或小麦基产品中烟酰胺辅酶降解的方法，包括向所述谷类粉基产品，例如小麦基产品等产品中加入有效量的核苷酸焦磷酸酶抑制剂。 本发明的另一方面是具有氨基酸N-末端序列为（G）IDDRHEVDLPPRP的核苷酸焦磷酸酶。 在本发明的另一方面，公开了一种包含核苷酸焦磷酸酶抑制剂如焦磷酸盐的面团，以及任选地包含至少一种NAD（P）或NAD（P）H依赖性氢化酶或脱氢酶的辅酶再生系统。 优选地，辅酶再生系统包含（由甘露糖醇脱氢酶和D-果糖组成）。