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    RATE INITIALIZATION AND OVERDRIVE PACING FOR CAPTURE THRESHOLD TESTING
    1.
    发明申请
    RATE INITIALIZATION AND OVERDRIVE PACING FOR CAPTURE THRESHOLD TESTING 审中-公开
    速率初始化和超速启动用于捕获阈值测试

    公开(公告)号：WO2012087515A3

    公开(公告)日：2012-10-18

    申请号：PCT/US2011062602

    申请日：2011-11-30

    Applicant: CARDIAC PACEMAKERS INC ,  ENROOTH ERIC K ,  SAHA SUNIPA ,  FOSTER CLAYTON ,  DONG YANTING

    Inventor： ENROOTH ERIC K ,  SAHA SUNIPA ,  FOSTER CLAYTON ,  DONG YANTING

    IPC: A61N1/37

    CPC classification number: A61N1/371 ,  A61N1/3714

    Abstract: Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.

    Abstract translation: 描述了在捕获阈值测试期间使用的速率初始化和过驱动起搏的方法。 检测心脏周期并监测心脏周期期间发生的心脏腔室的心脏事件。 计数心脏事件中的固有节拍数。 捕获阈值测试的初始化涉及如果心脏事件中的固有节拍数量小于阈值，则维持用于捕获阈值测试的预测试起搏速率。 如果心脏事件中的固有搏动次数大于阈值，则捕捉阈值测试的起搏速率增加。

    AN OFF-LINE SENSING METHOD AND ITS APPLICATIONS IN DETECTING UNDERSENSING, OVERSENSING, AND NOISE
    5.
    发明申请
    AN OFF-LINE SENSING METHOD AND ITS APPLICATIONS IN DETECTING UNDERSENSING, OVERSENSING, AND NOISE 审中-公开
    离线感测方法及其在检测，过滤和噪声检测中的应用

    公开(公告)号：WO2012166901A1

    公开(公告)日：2012-12-06

    申请号：PCT/US2012/040186

    申请日：2012-05-31

    Applicant: CARDIAC PACEMAKERS, INC ,  DONG, Yanting ,  ZHANG, Shijie ,  MAHAJAN, Deepa ,  LIU, Chenguang ,  LI, Dan ,  LIN, Yayun ,  BOHN, Derek D.

    Inventor： DONG, Yanting ,  ZHANG, Shijie ,  MAHAJAN, Deepa ,  LIU, Chenguang ,  LI, Dan ,  LIN, Yayun ,  BOHN, Derek D.

    IPC: A61N1/37

    CPC classification number: A61B5/0245 ,  A61B5/042 ,  A61B5/0452 ,  A61B5/7217 ,  A61N1/3704 ,  F04C2270/041

    Abstract: A system and method for performing independent, off-line evaluation of event sensing for collected electrograms, comprising: sensing an electrogram using an implantable medical device (IMD); determining locations of heart beats on at least one channel of the electrogram using a multi-pass process, resulting in a group of multi-pass beat locations; storing the electrogram and device-identified beat locations in a memory location; and retrieving the electrogram and device-identified beat locations from the memory location. The multi-pass process determines locations of heart beats on at least a first channel of the electrogram. The device-identified group of beat locations are then compared to the multi-pass group of beat locations identified using the multi-pass method. Based on the comparing step, oversensing of beats, undersensing of beats, or noise from the device can be detected.

    Abstract translation: 一种用于对收集的电描记图执行事件感测的独立离线评估的系统和方法，包括：使用可植入医疗装置（IMD）感测电描记图; 使用多遍处理确定心电图的至少一个通道上的心跳位置，从而产生一组多通拍位置; 将电描记图和设备识别的节拍位置存储在存储器位置中; 以及从存储器位置检索电描记图和设备标识的拍摄位置。 多遍处理确定心电图的至少第一个通道的位置。 然后将设备识别的拍摄位置组与使用多遍方法识别的拍摄位置的多通道组进行比较。 基于比较步骤，可以检测节拍过度，节拍不足或来自装置的噪音。

    ADAPTIVE EVENT STORAGE IN AN IMPLANTABLE DEVICE
    6.
    发明申请
    ADAPTIVE EVENT STORAGE IN AN IMPLANTABLE DEVICE 审中-公开
    自适应事件存储在可移植设备中

    公开(公告)号：WO2010138332A1

    公开(公告)日：2010-12-02

    申请号：PCT/US2010/035133

    申请日：2010-05-17

    Applicant: CARDIAC PACEMAKERS, INC. ,  DONG, Yanting ,  PERSCHBACHER, David L. ,  STAHMANN, Jeffrey E. ,  LI, Dan ,  MAHAJAN, Deepa

    Inventor： DONG, Yanting ,  PERSCHBACHER, David L. ,  STAHMANN, Jeffrey E. ,  LI, Dan ,  MAHAJAN, Deepa

    IPC: A61N1/372 ,  A61B5/00

    CPC classification number: A61N1/37252 ,  A61B5/02 ,  A61B5/04 ,  A61B5/0452 ,  A61B5/6846 ,  A61N1/025 ,  A61N1/3621 ,  A61N1/3702 ,  A61N1/372 ,  A61N1/3925

    Abstract: Monitoring physiological parameter using an implantable physiological monitor in order to detect a condition predictive of a possible future pathological episode and collecting additional physiological data associated with the condition predictive of a possible future pathological episode. Monitoring, using the physiological monitor, another physiological parameter in order to detect a condition indicative of the beginning of a present pathological episode and collecting additional pathological data in response to the condition. Determining that the condition predictive of a future episode and the condition indicative of a present episode are associated and, in response thereto, storing all the collected physiological data.

    Abstract translation: 使用植入式生理监测器监测生理参数，以便检测预测可能的未来病理发作的状况，并收集与预测可能的未来病理发作相关的条件相关的附加生理数据。 使用生理监测器监测另一种生理参数，以便检测指示本病理发作开始的病症并响应于该病症收集额外的病理数据。 确定预测未来事件的条件和指示当前情节的状况是相关联的，并且响应于此，存储所有收集的生理数据。

    IMPLANTABLE DEVICE WITH MULTIPLE PARAMETER SETS
    7.
    发明申请
    IMPLANTABLE DEVICE WITH MULTIPLE PARAMETER SETS 审中-公开
    具有多个参数集的可植入设备

    公开(公告)号：WO2008079347A1

    公开(公告)日：2008-07-03

    申请号：PCT/US2007/026191

    申请日：2007-12-21

    Applicant: CARDIAC PACEMAKERS, INC. ,  SATHAYE, Alok, S. ,  CAZARES, Shelley, M. ,  KRAMER, Andrew, P. ,  DONG, Yanting ,  WEI, Xuan ,  GARG, Ankur ,  NI, Quan

    Inventor： SATHAYE, Alok, S. ,  CAZARES, Shelley, M. ,  KRAMER, Andrew, P. ,  DONG, Yanting ,  WEI, Xuan ,  GARG, Ankur ,  NI, Quan

    IPC: A61N1/365 ,  A61N1/372 ,  G06F19/00 ,  A61N1/37

    CPC classification number: A61N1/3627 ,  A61N1/368 ,  A61N1/3688 ,  A61N1/37282 ,  G06F19/00 ,  G06F19/3418

    Abstract: An implantable device including a programmable controller can be used to include a user-specifiable therapy control parameter set. The therapy control parameter set may then be configured to include at least one therapy control parameter that is user-configurable to automatically switch from a first parameter value to a second parameter value at a time that occurs between separate user programming sessions of the device. A remote external interface can be included that is configured to be communicatively coupled to the device. The remote external interface can be configured to perform an analysis of physiologic data received from the device in response to operation of the device using a plurality of therapy control parameter sets. The remote external interface can further be configured to select a particular therapy control parameter set using the analysis.

    Abstract translation: 包括可编程控制器的可植入装置可以用于包括用户可指定的治疗控制参数组。 治疗控制参数集合然后可被配置为包括用户可配置的至少一个治疗控制参数，以便在设备的不同的用户编程会话之间发生的时刻自动地从第一参数值切换到第二参数值。 可以包括配置为通信地耦合到设备的远程外部接口。 远程外部接口可以被配置为响应于使用多个治疗控制参数组的设备的操作来执行从设备接收的生理数据的分析。 远程外部接口还可以配置为使用分析来选择特定的治疗控制参数集。

    CARDIAC RESYNCHRONIZATION THERAPY OPTIMIZATION USING CARDIAC ACTIVATION SEQUENCE INFORMATION
    8.
    发明申请
    CARDIAC RESYNCHRONIZATION THERAPY OPTIMIZATION USING CARDIAC ACTIVATION SEQUENCE INFORMATION 审中-公开
    使用心脏激活序列信息的心脏再生治疗优化

    公开(公告)号：WO2008063535A2

    公开(公告)日：2008-05-29

    申请号：PCT/US2007/023988

    申请日：2007-11-15

    Applicant: CARDIAC PACEMAKERS, INC. ,  ARCOT-KRISHNAMURTHY, Shantha ,  ZHANG, Yi ,  DING, Jiang ,  YU, Yinghong ,  DONG, Yanting

    Inventor： ARCOT-KRISHNAMURTHY, Shantha ,  ZHANG, Yi ,  DING, Jiang ,  YU, Yinghong ,  DONG, Yanting

    IPC: A61N1/365 ,  A61B5/0452

    CPC classification number: A61N1/3627 ,  A61B5/04011 ,  A61B5/0452 ,  A61N1/365 ,  A61N1/36535 ,  A61N1/36542

    Abstract: Systems and methods provide for pacing a heart to improve pumping efficiency of the heart, such as by producing a cardiac fusion response for patient's subject to cardiac ^synchronization therapy. A pacing parameter, such as an A-V delay, V-V delay, lead/electrode configuration or vector, is adjusted and a cardiac signal vector representative of all or a portion of one or more cardiac activation sequences is monitored during pacing parameter adjustment. A change in a characteristic of the cardiac signal vector is detected in response to an adjusted pacing parameter, the change indicative of a cardiac fusion response. A pacing therapy may be delivered to produce the cardiac fusion response using the adjusted pacing parameter.

    Abstract translation: 系统和方法提供用于起搏心脏以改善心脏的泵送效率，例如通过产生针对心脏同步治疗的患者的心脏融合反应。 调整起搏参数，例如A-V延迟，V-V延迟，引线/电极配置或载体，并且在起搏参数调整期间监测表示一个或多个心脏激活序列的全部或一部分的心脏信号载体。 响应于调整的起搏参数，指示心脏融合反应的变化来检测心脏信号载体的特性变化。 可以使用调整的起搏参数来递送起搏治疗以产生心脏融合反应。

    PROVIDING AUTHENTICATION OF REMOTELY COLLECTED EXTERNAL SENSOR MEASURES
    9.
    发明申请
    PROVIDING AUTHENTICATION OF REMOTELY COLLECTED EXTERNAL SENSOR MEASURES 审中-公开
    提供远程收集的外部传感器措施的认证

    公开(公告)号：WO2007070551A3

    公开(公告)日：2008-04-03

    申请号：PCT/US2006047485

    申请日：2006-12-11

    Applicant: CARDIAC PACEMAKERS INC ,  DONG YANTING ,  CARPENTER TODD P ,  NI QUAN ,  HOYME KENNETH P

    Inventor： DONG YANTING ,  CARPENTER TODD P ,  NI QUAN ,  HOYME KENNETH P

    IPC: A61B5/00

    CPC classification number: G06F19/3418 ,  A61B5/0002 ,  A61B5/117 ,  A61B5/1171 ,  G06Q50/24

    Abstract: A system (10) and method (30) for providing authentication of remotely collected external sensor (17) measures is presented. Physiological measures (37) are collected (31) from a source (17) situated remotely from a repository (18) for accumulating such collected physiological measures (37). An identification (32) of the source from which the physiological measures (37) were collected (31) is determined against authentication data (82) that uniquely identifies a specific patient (14). The physiological measures (37) are forwarded (33) to the repository upon authenticating the patient identification (80) as originating from the specific patient (14).

    Abstract translation: 提出了一种用于提供远程收集的外部传感器（17）测量的认证的系统（10）和方法（30）。 从远离储存库（18）的源（17）收集生理措施（37），用于积累这种收集的生理措施（37）。 根据唯一地识别特定患者（14）的认证数据（82）确定收集生理测量（37）的来源的识别（32）（31）。 在鉴定源自特定患者（14）的患者识别（80）时，将生理措施（37）转发（33）到储存库。

    ADJUSTING CARDIAC PACING RESPONSE SENSING INTERVALS
    10.
    发明申请
    ADJUSTING CARDIAC PACING RESPONSE SENSING INTERVALS 审中-公开
    调整心脏反应感应间隔

    公开(公告)号：WO2012075119A1

    公开(公告)日：2012-06-07

    申请号：PCT/US2011/062598

    申请日：2011-11-30

    Applicant: CARDIAC PACEMAKERS, INC. ,  DONG, Yanting ,  SHOME, Shibaji ,  MCCABE, Aaron ,  BRISBEN, Amy, J. ,  FOSTER, Clayton ,  YOST, David, W. ,  HAYES, Kenneth, N.

    Inventor： DONG, Yanting ,  SHOME, Shibaji ,  MCCABE, Aaron ,  BRISBEN, Amy, J. ,  FOSTER, Clayton ,  YOST, David, W. ,  HAYES, Kenneth, N.

    IPC: A61N1/37

    CPC classification number: A61N1/371 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/0456 ,  A61B5/4836 ,  A61B5/7217 ,  A61B5/7267 ,  A61N1/3712

    Abstract: Discrimination between different types of possible cardiac pacing responses may depend on the timing of expected features that are sensed within a temporal framework. The temporal framework may include classification intervals, blanking periods and appropriately timed back up paces. The classification intervals and blanking periods of the temporal framework are intervals of time that have time parameters that include start time, end time, and length. The relationships and timing parameters of the elements of the temporal framework, e.g., blanking periods, classification intervals, delay periods, and backup pacing, should support detection of features used to discriminate between different types of pacing responses. As the system learns the morphology of the particular patient by analyzing the waveform of the pacing response signal, the temporal framework for pacing response determination may be adjusted to accommodate the individual patient.

    Abstract translation: 不同类型的可能心脏起搏反应之间的歧视可能取决于在时间框架内感测到的预期特征的时间。 时间框架可以包括分类间隔，消隐期和适当定时的后台步数。 时间框架的分类间隔和消隐期是具有包括开始时间，结束时间和长度的时间参数的时间间隔。 时间框架的元素的关系和定时参数，例如消隐期，分类间隔，延迟周期和备份起搏应该支持用于区分不同类型的起搏响应的特征的检测。 当系统通过分析起搏响应信号的波形来学习特定患者的形态时，可调整起搏响应确定的时间框架以适应个体患者。

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