公开(公告)号：WO2010147983A1

公开(公告)日：2010-12-23

申请号：PCT/US2010/038665

申请日：2010-06-15

Applicant: CARDIAC PACEMAKERS, INC. ,  SAHA, Sunipa ,  ENROOTH, Eric, K. ,  BOON, Scot, C.

Inventor： SAHA, Sunipa ,  ENROOTH, Eric, K. ,  BOON, Scot, C.

IPC: A61N1/37 ,  A61N1/08 ,  G06K9/00 ,  A61B5/0428 ,  A61B5/0432

CPC classification number: A61N1/371 ,  A61B5/0428 ,  A61B5/0432 ,  A61B5/7203 ,  A61B5/7217 ,  A61N1/3714 ,  A61N1/3718 ,  G06K9/0051

Abstract: Embodiments of the invention are related to managing noise in sensed signals in implantable medical devices, amongst other things. In an embodiment the invention includes a method for processing electrical signals obtained from a patient including gathering a first set of electrical signals using an implantable medical device, filtering to provide a second set of electrical signals, the second set including frequencies above a threshold frequency, and estimating the amount of noise present in the first set of electrical signals based on the magnitude of the second set. In an embodiment, the invention includes a medical device configured to gather a first set of electrical signals, filter the first set to provide a second set of electrical signals including frequencies above a threshold frequency, and estimate the amount of noise present in the first set based on the magnitude of the second set. Other embodiments are also included herein.

Abstract translation: 本发明的实施例涉及管理可植入医疗装置中的感测信号中的噪声等。 在一个实施例中，本发明包括一种用于处理从患者获得的电信号的方法，包括使用可植入医疗装置收集第一组电信号，滤波以提供第二组电信号，所述第二组包括高于阈值频率的频率， 以及基于第二组的大小来估计存在于第一组电信号中的噪声量。 在一个实施例中，本发明包括被配置为收集第一组电信号的医疗设备，对第一组进行滤波以提供包括高于阈值频率的频率的第二组电信号，以及估计第一组中存在的噪声量 基于第二组的大小。 本文还包括其它实施例。

公开(公告)号：WO2012087515A4

公开(公告)日：2012-12-06

申请号：PCT/US2011062602

申请日：2011-11-30

Applicant: CARDIAC PACEMAKERS INC ,  ENROOTH ERIC K ,  SAHA SUNIPA ,  FOSTER CLAYTON ,  DONG YANTING

Inventor： ENROOTH ERIC K ,  SAHA SUNIPA ,  FOSTER CLAYTON ,  DONG YANTING

IPC: A61N1/37

CPC classification number: A61N1/371 ,  A61N1/3714

Abstract: Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.

Abstract translation: 描述捕获阈值测试期间使用的速率初始化和超速起搏的方法。 检测到心脏周期，并监测在心脏周期期间发生的心室的心脏事件。 计数心脏事件中的固有搏动次数。 捕获阈值测试的初始化涉及如果心脏事件中的固有搏动次数小于阈值，则保持捕获阈值测试的预先测试起搏速率。 如果心脏事件中的固有搏动次数大于阈值，则针对捕获阈值测试，起搏速率将增加。

公开(公告)号：WO2012087515A3

公开(公告)日：2012-10-18

申请号：PCT/US2011062602

申请日：2011-11-30

Applicant: CARDIAC PACEMAKERS INC ,  ENROOTH ERIC K ,  SAHA SUNIPA ,  FOSTER CLAYTON ,  DONG YANTING

Inventor： ENROOTH ERIC K ,  SAHA SUNIPA ,  FOSTER CLAYTON ,  DONG YANTING

IPC: A61N1/37

CPC classification number: A61N1/371 ,  A61N1/3714

Abstract: Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.

Abstract translation: 描述了在捕获阈值测试期间使用的速率初始化和过驱动起搏的方法。 检测心脏周期并监测心脏周期期间发生的心脏腔室的心脏事件。 计数心脏事件中的固有节拍数。 捕获阈值测试的初始化涉及如果心脏事件中的固有节拍数量小于阈值，则维持用于捕获阈值测试的预测试起搏速率。 如果心脏事件中的固有搏动次数大于阈值，则捕捉阈值测试的起搏速率增加。

公开(公告)号：WO2012087515A2

公开(公告)日：2012-06-28

申请号：PCT/US2011/062602

申请日：2011-11-30

Applicant: CARDIAC PACEMAKERS, INC. ,  ENROOTH, Eric, K. ,  SAHA, Sunipa ,  FOSTER, Clayton ,  DONG, Yanting

Inventor： ENROOTH, Eric, K. ,  SAHA, Sunipa ,  FOSTER, Clayton ,  DONG, Yanting

IPC: H05K7/20

CPC classification number: A61N1/371 ,  A61N1/3714

Abstract: Approaches for rate initialization and overdrive pacing used during capture threshold testing are described. Cardiac cycles are detected and the cardiac events of a cardiac chamber that occur during the cardiac cycles are monitored. The number of intrinsic beats in the cardiac events is counted. Initialization for a capture threshold test involves maintaining a pre-test pacing rate for the capture threshold test if the number of intrinsic beats in the cardiac events is less than a threshold. The pacing rate is increased for the capture threshold test if the number of intrinsic beats in the cardiac events is greater than the threshold.

Abstract translation: 描述了在捕获阈值测试期间使用的速率初始化和过驱动起搏的方法。 检测心脏周期并监测心脏周期期间发生的心脏腔室的心脏事件。 计数心脏事件中的固有节拍数。 捕获阈值测试的初始化涉及如果心脏事件中的固有节拍数量小于阈值，则维持用于捕获阈值测试的预测试起搏速率。 如果心脏事件的固有节拍数大于阈值，则捕获阈值测试的起搏速率会增加。

公开(公告)号：WO2012067935A1

公开(公告)日：2012-05-24

申请号：PCT/US2011/060165

申请日：2011-11-10

Applicant: CARDIAC PACEMAKERS, INC. ,  MASKARA, Barun ,  YU, Yinghong ,  TOCKMAN, Bruce A. ,  SAHA, Sunipa ,  MCDANIEL, Martin ,  ZHANG, Geng

Inventor： MASKARA, Barun ,  YU, Yinghong ,  TOCKMAN, Bruce A. ,  SAHA, Sunipa ,  MCDANIEL, Martin ,  ZHANG, Geng

IPC: A61N1/05 ,  A61B5/00

CPC classification number: A61N1/056 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/0472 ,  A61B5/6851 ,  A61N1/37241 ,  A61N2001/0585

Abstract: Cardiac lead implantation systems, devices, and methods for lead implantation are disclosed. An illustrative cardiac lead implantation system comprises a mapping guidewire including one or more electrodes configured for sensing cardiac electrical activity, a signal analyzer including an analysis module configured for analyzing an electrocardiogram signal sensed by the mapping guidewire, and a user interface configured for monitoring one or more hemodynamic parameters within the body. The sensed electrical activity signal can be used by the analysis module to compute a timing interval associated with ventricular depolarization.

Abstract translation: 公开了用于引线植入的心脏引线植入系统，装置和方法。 示例性心脏引线植入系统包括：映射导丝，其包括被配置为感测心脏电活动的一个或多个电极;信号分析器，包括被配置用于分析由所述映射导丝所感测的心电图信号的分析模块;以及用户界面，被配置为监视一个或 更多血液动力学参数在体内。 感测的电活动信号可以由分析模块用于计算与心室去极化相关的定时间隔。

公开(公告)号：WO2012019036A1

公开(公告)日：2012-02-09

申请号：PCT/US2011/046637

申请日：2011-08-04

Applicant: CARDIAC PACEMAKERS, INC. ,  SAHA, Sunipa ,  HAYES, Kenneth ,  HERRMANN, Keith L. ,  KALGREN, James ,  MCCABE, Aaron ,  ROCKWEILER, Holly ,  SHOME, Shibaji ,  SIEJKO, Krzysztof Z.

Inventor： SAHA, Sunipa ,  HAYES, Kenneth ,  HERRMANN, Keith L. ,  KALGREN, James ,  MCCABE, Aaron ,  ROCKWEILER, Holly ,  SHOME, Shibaji ,  SIEJKO, Krzysztof Z.

IPC: A61N1/372

CPC classification number: A61N1/37247 ,  A61N1/056 ,  A61N1/36185 ,  A61N1/3686 ,  A61N1/37241

Abstract: An interactive representation of electrostimulation electrodes or vectors can be provided, such as for configuring combinations of electrostimulation electrodes. In an example, electrodes or test parameters can be presented graphically or in a table. A user interface can be configured to receive user-input designating electrode combinations or vectors for test or for use in programming an implantable or ambulatory medical device. The interface can be used to indicate suggested electrode combinations or vectors in response to a first selection of an electrode. Tests can be performed on electrode combinations and vectors, and the results of the tests can be presented to a user using the interactive representation. In an example, test results can be analyzed by a processor and optionally used to program an implantable or ambulatory medical device.

Abstract translation: 可以提供电刺激电极或载体的交互式表示，例如用于配置电刺激电极的组合。 在一个示例中，电极或测试参数可以图形化或在表中呈现。 用户界面可以被配置为接收用户输入的指定电极组合或矢量，用于测试或用于编程可植入或动态医疗设备。 该界面可用于响应于电极的第一选择来指示建议的电极组合或载体。 可以对电极组合和载体进行测试，并且可以使用交互式表示向使用者呈现测试结果。 在一个示例中，测试结果可以由处理器分析，并且可选地用于编程可植入或移动的医疗设备。