公开(公告)号：WO2010083167A3

公开(公告)日：2010-09-23

申请号：PCT/US2010020792

申请日：2010-01-12

Applicant: SILK ROAD MEDICAL INC ,  GARRISON MICHI E ,  CHOU TONY M

Inventor： GARRISON MICHI E ,  CHOU TONY M

IPC: A61M25/10 ,  A61B17/12 ,  A61F2/84 ,  A61M1/36 ,  A61M29/02

CPC classification number: A61M25/10 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12136 ,  A61B17/12145 ,  A61B2017/12063 ,  A61F2/95 ,  A61M1/3613 ,  A61M1/3621 ,  A61M25/04 ,  A61M25/0662 ,  A61M25/104 ,  A61M2025/0042 ,  A61M2025/0681 ,  A61M2025/1052 ,  A61M2210/0693

Abstract: A system of devices for treating cerebral artery disease or the brain includes an arterial access sheath (110) adapted to be introduced into a common carotid, internal carotid, or vertebral artery through a penetration in the artery and receive blood from the artery. The system further includes a shunt (120) fluidly connected to the arterial access sheath, wherein the shunt provides a pathway for blood to flow from the arterial access sheath to a return site, and a flow control assembly (125) coupled to the shunt (120) and adapted to regulate blood flow through the shunt (120). A treatment device (15) is adapted to be introduced into the artery through the arterial access sheath (110) and is configured to treat the cerebral artery or brain.

Abstract translation: 用于治疗脑动脉疾病或大脑的装置系统包括适于通过动脉穿透并从动脉接受血液而被引入颈总动脉，颈内动脉或椎动脉的动脉通路鞘（110）。 所述系统还包括流体连接到所述动脉通路护套的分流器（120），其中所述分流器提供血液从所述动脉通路护套流向返回位置的路径，以及流动控制组件（125），其耦合到所述分流器 120）并且适于调节通过分流器（120）的血流。 治疗装置（15）适于通过动脉通路护套（110）引入动脉，并且构造成治疗大脑动脉或脑。

公开(公告)号：WO2010019719A3

公开(公告)日：2010-05-27

申请号：PCT/US2009053621

申请日：2009-08-12

Applicant: SILK ROAD MEDICAL INC ,  GARRISON MICHI E ,  HYDE GREGORY M ,  RENATI RICHARD ,  SCHAER ALAN ,  CHOU TONY M

Inventor： GARRISON MICHI E ,  HYDE GREGORY M ,  RENATI RICHARD ,  SCHAER ALAN ,  CHOU TONY M

IPC: A61B17/04 ,  A61F2/06 ,  A61M25/04

CPC classification number: A61B17/0057 ,  A61B17/0469 ,  A61B2017/00663 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/22038 ,  A61B2017/22067 ,  A61F2/856 ,  A61F2/954 ,  A61F2/966 ,  A61F2002/061 ,  A61M25/04 ,  A61M25/0618 ,  A61M25/0662 ,  A61M25/10 ,  A61M2025/1052

Abstract: A suture-based vessel closure device can perform the dilation of an arteriotomy puncture and does not require previous dilation of the arteriotomy puncture by a separate device or by a procedural sheath dilator. The suture- based vessel closure device can place one or more sutures across the vessel access site such that, when the suture ends are tied off after sheath removal, the stitch or stitches provide hemostasis to the access site.

Abstract translation: 基于缝线的血管闭合装置可以执行动脉切口穿刺的扩张，并且不需要通过单独的装置或通过手术鞘扩张器预先扩张动脉切口穿刺。 基于缝线的血管闭合装置可以将一根或多根缝合线放置在血管进入部位上，使得当在鞘去除后将缝合线端部系起来时，一个或多个缝合线为进入部位提供止血。

公开(公告)号：WO2013022796A3

公开(公告)日：2013-04-25

申请号：PCT/US2012049643

申请日：2012-08-03

Applicant: SILK ROAD MEDICAL INC ,  GARRISON MICHI E ,  CHOU TONY M ,  HYDE GREGORY M ,  SCHAER ALAN K

Inventor： GARRISON MICHI E ,  CHOU TONY M ,  HYDE GREGORY M ,  SCHAER ALAN K

IPC: A61B17/22 ,  A61B17/3207 ,  A61M25/088 ,  A61M25/09 ,  A61M25/098

CPC classification number: A61B17/22 ,  A61B17/221 ,  A61B17/32037 ,  A61B2017/22034 ,  A61B2017/22038 ,  A61B2017/22039 ,  A61B2017/22044 ,  A61B2017/22054 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2017/2212 ,  A61B2017/2217 ,  A61F2/013 ,  A61M1/0072 ,  A61M1/1037 ,  A61M1/1062 ,  A61M1/3621 ,  A61M25/0068 ,  A61M25/0169 ,  A61M25/0662 ,  A61M2025/0681

Abstract: Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.

Abstract translation: 描述了脑动脉脉管系统的子宫颈进入和脑阻塞治疗（包括缺血性卒中）的方法和系统。 方法和装置可以包括可以提供抽吸和被动流逆转的方法和装置，那些在手术期间保护脑半暗带以最小化对脑的损伤，以及用于去除闭塞的远端导管和装置的方法和装置。 提供被动流逆转的方法和装置也可以向用户提供一定程度的流量控制。 还描述了提供一种方法来安全地关闭颈动脉中的进入部位以避免子宫颈血肿的潜在破坏性后果的装置和方法。

公开(公告)号：WO2012021406A3

公开(公告)日：2012-02-16

申请号：PCT/US2011/046775

申请日：2011-08-05

Applicant: SILK ROAD MEDICAL, INC. ,  RYAN, Ari ,  SCHAER, Alan, K. ,  HYDE, Gregory, M. ,  RENATI, Richard, J. ,  GARRISON, Michi, E.

Inventor： RYAN, Ari ,  SCHAER, Alan, K. ,  HYDE, Gregory, M. ,  RENATI, Richard, J. ,  GARRISON, Michi, E.

IPC: A61B17/34 ,  A61M39/06 ,  A61M25/01 ,  A61B17/00 ,  A61F2/84

Abstract: Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery. Embodiments of the systems and methods can be used in combination with embolic protection systems including blood flow reversal mechanisms, arterial filters, and arterial occlusion devices.

公开(公告)号：WO2011106547A3

公开(公告)日：2011-12-29

申请号：PCT/US2011026105

申请日：2011-02-24

Applicant: SILK ROAD MEDICAL INC ,  GARRISON MICHI E ,  CHOU TONY M ,  HYDE GREGORY M

Inventor： GARRISON MICHI E ,  CHOU TONY M ,  HYDE GREGORY M

IPC: A61F2/24 ,  A61B17/03 ,  A61B17/34 ,  A61F2/958 ,  A61M29/00

CPC classification number: A61F2/24 ,  A61B17/0401 ,  A61B17/12122 ,  A61B2017/0409 ,  A61F2/013 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2002/018 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0067

Abstract: Devices and methods are configured to allow transcervical or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure.

Abstract translation: 装置和方法被配置为允许经颈总动脉或锁骨下入口通过颈总动脉至天然主动脉瓣，并将假体主动脉瓣植入心脏。 该装置和方法还提供了在这种血管内主动脉瓣膜植入过程期间用于栓塞保护的手段。

公开(公告)号：WO2010141850A1

公开(公告)日：2010-12-09

申请号：PCT/US2010/037448

申请日：2010-06-04

Applicant: ENTRIGUE SURGICAL, INC. ,  GONZALES, Donald, A. ,  DINGER, III, Fred, B. ,  NALLURI, Prasad ,  WRANA, Jeffrey, S. ,  NIEDERAUER, Gabriele, G. ,  GARRISON, Michi, E.

Inventor： GONZALES, Donald, A. ,  DINGER, III, Fred, B. ,  NALLURI, Prasad ,  WRANA, Jeffrey, S. ,  NIEDERAUER, Gabriele, G. ,  GARRISON, Michi, E.

IPC: A61M29/00 ,  A61B17/24

CPC classification number: A61B17/24 ,  A61B2017/00318 ,  A61B2017/22051 ,  A61F2/04 ,  A61F2/958 ,  A61F2002/30062 ,  A61F2210/0004 ,  A61F2250/0067 ,  A61M29/02

Abstract: A system, device and method for dilating an anatomical structure. Systems, devices and methods may comprise a therapeutic component configured to treat a paranasal sinus. Specific embodiments may comprise a shaft with an articulating portion.

Abstract translation: 用于扩张解剖结构的系统，装置和方法。 系统，装置和方法可以包括构造成治疗鼻旁窦的治疗部件。 具体实施例可以包括具有铰接部分的轴。

公开(公告)号：WO2009012473A3

公开(公告)日：2009-04-23

申请号：PCT/US2008070542

申请日：2008-07-18

Applicant: SILK ROAD MEDICAL INC ,  CRIADO ENRIQUE ,  CHOU TONY M ,  GARRISON MICHI E ,  HYDE GREGORY M ,  SCHAER ALAN ,  RENATI RICHARD

Inventor： CRIADO ENRIQUE ,  CHOU TONY M ,  GARRISON MICHI E ,  HYDE GREGORY M ,  SCHAER ALAN ,  RENATI RICHARD

IPC: A61M25/00 ,  A61B17/22 ,  A61F2/06 ,  A61F2/90 ,  A61M29/02

CPC classification number: A61M1/3655 ,  A61B8/06 ,  A61B8/488 ,  A61B17/12045 ,  A61B17/12109 ,  A61B2017/00778 ,  A61B2017/12127 ,  A61B2017/320716 ,  A61F2/82 ,  A61F2/90 ,  A61F2/95 ,  A61F2/954 ,  A61F2002/065 ,  A61F2250/0037 ,  A61M1/34 ,  A61M1/36 ,  A61M1/3613 ,  A61M1/3659 ,  A61M5/007 ,  A61M25/10 ,  A61M29/02 ,  A61M39/06 ,  A61M39/22 ,  A61M2025/1052 ,  A61M2205/33 ,  A61M2205/3331 ,  A61M2205/3334

Abstract: Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.

Abstract translation: 颈内动脉的介入手术通过经颈进入进行，同时从颈内动脉到静脉或外部位置建立逆行血流。 用于接近和治疗颈动脉的系统包括动脉进入装置，流体地连接到动脉进入装置的分流器以及流量控制组件，流量控制组件耦合到分流器并且适于调节通过分流器的血液流量，所述血液流量至少在第一 血流状态和至少第二血流状态。 流量控制组件包括一个或多个与通过分流管的血流相互作用的部件。

公开(公告)号：WO2012021406A2

公开(公告)日：2012-02-16

申请号：PCT/US2011046775

申请日：2011-08-05

Applicant: SILK ROAD MEDICAL INC ,  RYAN ARI ,  SCHAER ALAN K ,  HYDE GREGORY M ,  RENATI RICHARD J ,  GARRISON MICHI E

Inventor： RYAN ARI ,  SCHAER ALAN K ,  HYDE GREGORY M ,  RENATI RICHARD J ,  GARRISON MICHI E

IPC: A61B17/34 ,  A61B17/00 ,  A61F2/84 ,  A61M25/01 ,  A61M39/06

CPC classification number: A61M39/06 ,  A61B17/0057 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0483 ,  A61B17/0625 ,  A61B17/3415 ,  A61B2017/00238 ,  A61B2017/00646 ,  A61B2017/00654 ,  A61B2017/00663 ,  A61B2017/00668 ,  A61B2017/0472 ,  A61B2017/0477 ,  A61B2017/06042 ,  A61B2017/0641 ,  A61B2090/0811 ,  A61M39/0606 ,  A61M39/227 ,  A61M39/228

Abstract: Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery. Embodiments of the systems and methods can be used in combination with embolic protection systems including blood flow reversal mechanisms, arterial filters, and arterial occlusion devices.

Abstract translation: 系统和方法适用于治疗颈动脉。 该系统包括适于宫颈插入颈动脉的介入导管和血管通路装置。 系统和方法的实施例可以与包括血流反转机构，动脉过滤器和动脉闭塞装置在内的栓塞保护系统结合使用。

公开(公告)号：WO2011106547A2

公开(公告)日：2011-09-01

申请号：PCT/US2011/026105

申请日：2011-02-24

Applicant: SILK ROAD MEDICAL, INC. ,  GARRISON, Michi, E. ,  CHOU, Tony, M. ,  HYDE, Gregory, M.

Inventor： GARRISON, Michi, E. ,  CHOU, Tony, M. ,  HYDE, Gregory, M.

IPC: A61F2/24 ,  A61B17/34 ,  A61M25/10 ,  A61B17/03 ,  A61M29/00

CPC classification number: A61F2/24 ,  A61B17/0401 ,  A61B17/12122 ,  A61B2017/0409 ,  A61F2/013 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2002/018 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0067

Abstract: Devices and methods are configured to allow transcervical or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure.

Abstract translation: 装置和方法被配置为允许通过颈总动脉到天然主动脉瓣的子宫颈或锁骨下进入，以及将假体主动脉瓣植入心脏。 这些装置和方法还提供了在这样的血管内主动脉瓣植入过程中用于栓塞保护的装置。

公开(公告)号：WO2009100210A1

公开(公告)日：2009-08-13

申请号：PCT/US2009/033208

申请日：2009-02-05

Applicant: SILK ROAD MEDICAL, INC. ,  CHOU, Tony, M. ,  GARRISON, Michi, E. ,  HYDE, Gregory, M. ,  RENATI, Richard ,  SCHAER, Alan

Inventor： CHOU, Tony, M. ,  GARRISON, Michi, E. ,  HYDE, Gregory, M. ,  RENATI, Richard ,  SCHAER, Alan

IPC: A61F2/84

CPC classification number: A61M25/10 ,  A61B34/30 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/9583

Abstract: An interventional catheter is adapted for treating a blood vessel. In an embodiment, the catheter includes an elongate shaft sized for insertion in a blood vessel and a stent positioned on a distal region of the elongate shaft. An expandable dilation member is coupled to a distal region of the elongate shaft. The expandable dilation member is adapted to expand outward. A stent containment member is positioned over the elongate shaft and the stent to contain the stent in a collapsed state.

Abstract translation: 介入导管适于治疗血管。 在一个实施例中，导管包括尺寸适于插入血管的细长轴和位于细长轴的远侧区域上的支架。 可膨胀扩张构件联接到细长轴的远侧区域。 可膨胀扩张构件适于向外扩张。 支架容纳构件定位在细长轴和支架上方以使支架处于折叠状态。