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    CONDENSATE COLORIMETRIC NITROGEN OXIDE ANALYZER
    4.
    发明申请
    CONDENSATE COLORIMETRIC NITROGEN OXIDE ANALYZER 审中-公开
    浓缩色素​​氮氧化物分析仪

    公开(公告)号：WO1997035519A1

    公开(公告)日：1997-10-02

    申请号：PCT/US1997004848

    申请日：1997-03-25

    申请人： GASTON, Benjamin, M., IV ,  HUNT, John, F.

    IPC分类号： A61B05/08

    CPC分类号： A61B5/083

    摘要： Disclosed is a device for determination of the content of higher oxides of nitrogen in exhaled breath condensate which comprises a conduit (7) having an exhaling condensing portion with an inlet and an outlet (the inlet can be configured to fit with a mechanical respirator, or for direct use by a patient, an inlet assembly providing one-way ingress (2) of ambient atmosphere so the device can be associated with the inlet of the conduit exhaling condensing portion); a coolant jacket (6) coaxially surrounding said exhaling condensing portion; a gas release port; and, in an enclosed fluid communication with said conduit exhaling condensing portion outlet, a sample assay assembly (9) comprising the following: (a) a translucent analysis chamber attached to the outlet to receive condensate fluid and having a reagent port; (b) a reagent chamber in enclosed fluid communication with the reagent entry port; and (c) a pliable element connecting the oulet and the analysis chamber and forming a portion of the reagent chamber such that flexion of the pliable element closes communication between the oulet and the analysis chamber and contracts the reagent chamber so as to deliver to the analysis chamber controlled amounts of condensate and reagent. The device is disposable and inexpensive, and is used to collect human exhaling for colorimetric assay of liquid and gas phase nitrogen oxides to assist in evaluation of airway inflammation.

    摘要翻译： 公开了一种用于确定呼出气体冷凝物中较高氧化氮含量的装置，其包括具有带入口和出口的排气冷凝部分的导管（该入口可配置成与机械呼吸器配合，或 由患者直接使用，入口组件提供环境大气的单向入口（2），因此该装置可与导管排出冷凝部分的入口相关联）; 围绕所述排气冷凝部分的冷却剂套（6）; 气体释放口; 并且在与所述导管排出冷凝部分出口的封闭流体连通中，包括以下的样品测定组件（9）：（a）连接到出口以接收冷凝物流体并具有试剂口的半透明分析室; （b）与所述试剂入口封闭流体连通的试剂室; 和（c）连接所述分离室和所述分析室的柔性元件，并且形成所述试剂室的一部分，使得所述柔韧元件的屈曲闭合所述底座和所述分析室之间的连通并收缩所述试剂室以便输送到所述分析 室内控制量的冷凝物和试剂。 该装置是一次性和便宜的，并且用于收集人呼气以进行液相和气相氮氧化物的比色测定以帮助评估气道炎症。

    CUT-FOLD SHAPE TECHNOLOGY FOR ENGINEERED MOLDED FIBER BOARDS
    5.
    发明申请
    CUT-FOLD SHAPE TECHNOLOGY FOR ENGINEERED MOLDED FIBER BOARDS 审中-公开
    用于工程塑料纤维板的切割成形技术

    公开(公告)号：WO2012075430A1

    公开(公告)日：2012-06-07

    申请号：PCT/US2011/063134

    申请日：2011-12-02

    申请人： THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE ,  UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF AGRICULTURE ,  HERDT, Julee Ann ,  SCHAUERMANN, Kellen Scott ,  HUNT, John F.

    发明人： HERDT, Julee Ann ,  SCHAUERMANN, Kellen Scott ,  HUNT, John F.

    IPC分类号： G06F17/50 ,  B29C53/02

    CPC分类号： G06F17/50 ,  B29C53/063 ,  B29K2105/08

    摘要： A three-dimensional engineered shaped fiber configuration is formed using determined structural requirements for a three-dimensional engineered shaped fiber configuration and ascertained properties of an engineered molded fiber fiberboard material. A first cut on a top surface and a second cut on a bottom surface of the fiberboard material are calculated. These calculations are based, at least in part, on the structural requirements properties of the fiberboard material. The first cut and the second cut each have a depth, a width, and a position. The first cut and the second cut have a spacing between them such that the flat piece of fiberboard material can be folded at a point located in the spacing between the first cut and second cut to position a first portion of the fiberboard material at a particular angle with respect to a second portion of the fiberboard material.

    摘要翻译： 使用对三维工程成型纤维构型的确定的结构要求并确定工程塑造的纤维素纤维板材料的特性来形成三维工程成型纤维构型。 计算出纤维板材料的顶面上的第一切口和底面的第二切口。 这些计算至少部分地基于纤维板材料的结构要求性质。 第一切割和第二切割各自具有深度，宽度和位置。 第一切割和第二切口在它们之间具有间隔，使得平坦的纤维板材料片可以在位于第一切割和第二切口之间的间隔处的点处折叠，以将纤维板材料的第一部分以特定角度 相对于纤维板材料的第二部分。

    BREATH TEST FOR ASSESSING DISEASES, PARTICULARLY ASTHMA
    6.
    发明申请
    BREATH TEST FOR ASSESSING DISEASES, PARTICULARLY ASTHMA 审中-公开

    公开(公告)号：WO2002082977A3

    公开(公告)日：2002-10-24

    申请号：PCT/US2002/015250

    申请日：2002-04-17

    申请人： UNIVERSITY OF VIRGINIA PATENT FOUNDATION ,  VAUGHAN, John, W. ,  HUNT, John, F. ,  GASTON, Benjamin, M. ,  MACDONALD, Timothy, L.

    发明人： VAUGHAN, John, W. ,  HUNT, John, F. ,  GASTON, Benjamin, M. ,  MACDONALD, Timothy, L.

    IPC分类号： A61B05/00

    摘要： A device and method for non-invasively monitoring asthma and other respiratory and non-respiratory diseases. The method includes collecting condensate from a subject's breath, testing the condensate to determine its acetic acid/acetate level or concentration, and evaluating these properties to determine the presence, absence or status of a respiratory or non-respiratory disease in the subject. The method may also include, before the testing step, standardizing the volatile substances that may be present in the condensate in a degassing or gas standardizing step. The device (10) includes a mouthpiece apparatus (20) for receiving a subject's breath, a condensation apparatus (60) to condense the subject's breath and produce a condensate, and a collection apparatus (100) having a collection chamber (102) containing means (116) for testing the condensate to determine the acetic acid or acetate concentration. The device may also include a system (150) for removing or standardizing the volatile substances that may be present with the condensate.

    DEVICE AND METHOD FOR MONITORING ASTHMA
    9.
    发明申请
    DEVICE AND METHOD FOR MONITORING ASTHMA 审中-公开
    用于监测ASTHMA的装置和方法

    公开(公告)号：WO0035337A9

    公开(公告)日：2001-07-19

    申请号：PCT/US9930184

    申请日：1999-12-17

    申请人： UNIV VIRGINIA ,  HUNT JOHN F ,  GASTON BENJAMIN M

    发明人： HUNT JOHN F ,  GASTON BENJAMIN M

    IPC分类号： A61B5/087 ,  A61B5/097 ,  G01N33/48 ,  G01N33/497 ,  A61B5/08

    CPC分类号： A61B5/411 ,  A61B5/087 ,  A61B5/097 ,  G01N33/497

    摘要： A device (10) and method for non-invasively monitoring asthma and other respiratory diseases. The method includes collecting condensate from a subject's breath, testing the condensate to determine its acidity level or ammonium concentration, and evaluating these properties to determine the presence, absence or status of a respiratory disease in the subject. The method may also include, prior to the testing step, standardizing the volatile substances that may be present within the condensate in a degassing or gas standardizing step. The device (10) includes a mouthpiece apparatus (20) configured to receive breath from a subject, a condensation apparatus (60) to condense the subject's breath and produce a condensate, and a collection apparatus (100) having a collection chamber (102) containing means for testing the condensate to determine its chemical properties. The device (10) also include a system for removing or standardizing the volatile substances that may be present with the condensate.

    摘要翻译： 一种用于非侵入性监测哮喘和其他呼吸系统疾病的装置（10）和方法。 该方法包括从受试者的呼吸中收集冷凝物，测试冷凝物以确定其酸度水平或铵浓度，并评估这些性质以确定受试者中呼吸系统疾病的存在，不存在或状态。 该方法还可以包括在测试步骤之前，在脱气或气体标准化步骤中将可能存在于冷凝物内的挥发性物质标准化。 装置（10）包括构造成从受试者接收呼吸的接口装置（20），冷凝装置（60），用于冷凝受试者的呼吸并产生冷凝物，以及具有收集室（102）的收集装置（100） 包含用于测试冷凝物以确定其化学性质的装置。 装置（10）还包括用于去除或标准化可能与冷凝物一起存在的挥发性物质的系统。