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公开(公告)号：WO2017001824A2
公开(公告)日：2017-01-05
申请号：PCT/GB2016/051859
申请日：2016-06-21
发明人： ROBBINS, Peter Alistair , O'NEILL, David , COUPER, John , HANCOCK, Gus , RITCHIE, Grant , CIAFFONI, Luca
CPC分类号： G01F1/36 , A61B5/0833 , A61B5/0836 , A61B5/087 , A61M2016/0036 , A61M2016/1025 , A61M2230/432 , G01N21/031 , G01N21/3504 , G01N21/39
摘要： A molecular flow sensor comprises a flowmeter integrated with an in airway laser gas analyser. The laser gas analyser spectroscopically analyses the concentrations of gases such as oxygen, carbon dioxide and water in a measurement space which is in the gas flow path between two Lilly-type flow-sensing mesh screens. The gas flow through the measurement space is measured by measuring the pressure drop across the flow-sensing mesh screens using a differential pressure sensor. Helical baffles are provided upstream and downstream of the measurement space to provide a low resistance gas flow path while blocking ambient light from entering the measurement space, and flow-conditioning elements of mesh or metal foam are provided between the helical baffles and the flow- sensing meshes. Pressure averaging is conducted circumferentially around the gas flow path by the use of circumferentially spaced gas sensing holes connected to a pressure averaging channel which communicates with the differential pressure sensor. The differential pressure sensor is composed of an array of individual pressure sensors to improve baseline stability and linearity. At least two independent pressure sensors may be provided, switchable out independently to allow regular calibration while the other is still measuring. The flow sensor is particularly useful for measuring respiratory gas exchange such as oxygen consumption or carbon dioxide production by a respiring subject.
摘要翻译： 分子流量传感器包括与气道内激光气体分析仪集成的流量计。 激光气体分析仪通过光谱分析在两个礼来型流量感应筛网之间的气体流动路径中的测量空间中的气体浓度，例如氧气，二氧化碳和水。 通过测量空间的气体流量通过使用压差传感器测量流量感测网筛两端的压降来测量。 螺旋挡板设置在测量空间的上游和下游，以提供低电阻气体流动路径，同时阻止环境光进入测量空间，并且网状或金属泡沫的流动调节元件设置在螺旋折流板和流量感测器之间 网格。 通过使用与压差平均通道连接的周向间隔的气体传感孔，在气体流动路径周围进行压力平均。压力平均通道与差压传感器连通。 差压传感器由一系列单独的压力传感器组成，以提高基线稳定性和线性度。 至少可以提供两个独立的压力传感器，可独立切换以允许常规校准，而另一个仍在测量。 流量传感器特别适用于测量呼吸气体交换，例如呼吸主体的氧气消耗或二氧化碳产生。
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公开(公告)号：WO2016203264A1
公开(公告)日：2016-12-22
申请号：PCT/GB2016/051827
申请日：2016-06-17
发明人： EDWARDS, Peter P , KUZNETSOV, Vladimir L , XIAO, Tiancun , SLOCOMBE, Daniel , GONZALEZ-CORTES, Sergio , AL-MEGREN, Hamid , ALDAWSARI, Afrah , ALKINANI, Mohammad
CPC分类号： C01B3/26 , B01J19/126 , C01B2203/0277 , C01B2203/0855 , C01B2203/1047 , C01B2203/1058 , C01B2203/1064 , C01B2203/107 , C01B2203/1082 , C01B2203/1211 , C01B2203/1247 , C01B2203/1276
摘要： The invention provides a process for producing hydrogen, which process comprises exposing a composition to electromagnetic radiation, which composition comprises at least one organic compound and a catalyst, wherein the at least one organic compound is selected from: hydrocarbons and compounds which comprise a hydrocarbyl group, and the catalyst comprises: a metal in elemental form; a metal compound other than a metal oxide; a non- metal in elemental form selected from B, C, Si, P, Ge, As, Sb and Te; or an inorganic compound of said non-metal other than an oxide of the non-metal. Compositions as defined above are also provided, as are uses of the compositions as hydrogen storage materials or for generating hydrogen. An electromagnetic activation system suitable for the rapid production of hydrogen from hydrocarbons is also provided, which system comprises: a reactor comprising a reaction cavity, which reactor is configured to receive, in the reaction cavity, a composition to be decomposed, and is configured to deliver hydrogen; and a source of electromagnetic radiation, suitable for exposing a composition in the reaction cavity to electromagnetic radiation and thereby effecting decomposition of the composition to produce hydrogen. Further provided is the use of electromagnetic activation system of the invention as defined above for generating hydrogen from a composition of the invention as defined above. A system for generating hydrogen is also provided, comprising (a) a composition of the invention; and (b) a source of electromagnetic radiation, for exposing the composition to electromagnetic radiation and thereby effecting decomposition of the at least one organic compound to produce hydrogen.
摘要翻译： 本发明提供一种生产氢的方法，该方法包括将组合物暴露于电磁辐射，该组合物包含至少一种有机化合物和催化剂，其中至少一种有机化合物选自：烃和包含烃基的化合物 ，并且催化剂包括：元素形式的金属; 除金属氧化物以外的金属化合物; 选自B，C，Si，P，Ge，As，Sb和Te的元素形式的非金属; 或所述非金属的无机化合物，而不是非金属的氧化物。 还提供了如上所述的组合物，组合物用作储氢材料或用于产生氢。 还提供了适用于从烃快速生产氢的电磁激活系统，该系统包括：包含反应腔的反应器，该反应器构造成在反应腔中接收待分解的组合物， 输送氢气; 和电磁辐射源，适于将反应腔中的组合物暴露于电磁辐射，从而分解组合物以产生氢。 还提供了如上定义的本发明的电磁激活系统用于由如上定义的本发明的组合物产生氢的用途。 还提供了一种产生氢气的系统，包括（a）本发明的组合物; 和（b）电磁辐射源，用于将组合物暴露于电磁辐射，从而使至少一种有机化合物分解以产生氢。
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公开(公告)号：WO2016166550A1
公开(公告)日：2016-10-20
申请号：PCT/GB2016/051059
申请日：2016-04-15
CPC分类号： A61K41/0038 , A61L24/001 , A61L24/02 , A61L2400/12 , A61L2430/36
摘要： The present invention relates to an embolization particle comprising a microparticle coated with a plurality of nanoparticles, which nanoparticles comprise a metal oxide doped with one or more rare earth elements, wherein the metal oxide is titanium dioxide, zinc oxide or cerium dioxide. An embolization particle of the invention for use in the treatment of cancer in combination with X-ray radiation or proton beam radiation, or use in embolization, is also described. The invention also relates to a process for producing an embolization particle comprising a microparticle coated with a plurality of nanoparticles, which nanoparticles comprise a metal oxide doped with one or more rare earth elements, wherein the metal oxide is titanium dioxide, zinc oxide or cerium dioxide, which process comprises: (i) providing a microparticle; (ii) contacting the microparticle with a plurality of the nanoparticles; and (iii) heating the microparticle and the nanoparticles to form the embolization particle.
摘要翻译： 本发明涉及包含涂覆有多个纳米颗粒的微粒的栓塞颗粒，该纳米颗粒包含掺杂有一种或多种稀土元素的金属氧化物，其中金属氧化物是二氧化钛，氧化锌或二氧化铈。 还描述了本发明的用于治疗癌症的结合X射线辐射或质子束辐射或用于栓塞的栓塞颗粒。 本发明还涉及一种用于生产包含涂覆有多个纳米颗粒的微粒的栓塞颗粒的方法，该纳米颗粒包含掺杂有一种或多种稀土元素的金属氧化物，其中金属氧化物是二氧化钛，氧化锌或二氧化铈 ，该方法包括：（i）提供微粒; （ii）使微粒与多个纳米粒子接触; 和（iii）加热微粒和纳米颗粒以形成栓塞颗粒。
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公开(公告)号：WO2016120606A1
公开(公告)日：2016-08-04
申请号：PCT/GB2016/050162
申请日：2016-01-26
发明人： DAVIS, Jason , BUENO, Paulo Roberto
IPC分类号： G01N27/02 , G01N33/543
CPC分类号： G01N27/221 , G01N27/026 , G01N27/227 , G01N27/27 , G01N33/5438 , G01N33/68 , G01N2333/4737 , G01R27/2605 , H01L29/1606 , H01L31/115
摘要： The present application relates to a sensing method that is carried out using an electrode that comprises an electrode substrate functionalised with sensing elements. The method involves conducting electrochemical impedance spectroscopy at a plurality of applied voltages and then integrating measurement data as a function of voltage. Also provided is an apparatus for carrying out the sensing method. The method and apparatus arc suitable for a broad range of sensing applications, including the detection of diagnostic biomarkers, drug screening, development of glycoarray systems and the sensing of environmental parameters such as light intensity, temperature and humidity.
摘要翻译： 本申请涉及使用包括用感测元件功能化的电极基底的电极进行的感测方法。 该方法包括在多个施加的电压下进行电化学阻抗谱，然后将测量数据作为电压的函数进行积分。 还提供了一种用于执行感测方法的装置。 该方法和设备适用于广泛的感测应用，包括诊断生物标志物的检测，药物筛选，糖阵列系统的开发以及诸如光强度，温度和湿度等环境参数的检测。
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公开(公告)号：WO2016097723A1
公开(公告)日：2016-06-23
申请号：PCT/GB2015/054033
申请日：2015-12-16
CPC分类号： G01N27/18 , G01N25/00 , G01N25/08 , G01N25/18 , G01N25/482 , G01N33/2847 , G01N33/2858
摘要： The invention relates to detecting a composition of a sample or contamination in liquids by detecting corresponding changes in their thermal properties. In a disclosed arrangement, an apparatus is provided comprising a first probe element configured to provide a first surface in direct contact with the sample and a second surface that is not in direct contact with the sample. A measurement system measures a rate of heat transfer through the first surface. A processing unit analyses the measured rate of heat transfer in order to detect a heat transfer characteristic of the sample that is indicative of a composition of the sample.
摘要翻译： 本发明涉及通过检测其热性质的相应变化来检测样品的组成或液体中的污染物。 在公开的布置中，提供了一种装置，其包括第一探针元件，其构造成提供与样品直接接触的第一表面和不与样品直接接触的第二表面。 测量系统测量通过第一表面的传热速率。 处理单元分析测量的传热速率，以便检测指示样品组成的样品的传热特性。
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公开(公告)号：WO2016092325A1
公开(公告)日：2016-06-16
申请号：PCT/GB2015/053870
申请日：2015-12-11
IPC分类号： A61K49/18
CPC分类号： A61K49/1863 , A61K49/0008 , A61K49/085 , G01N33/587
摘要： The invention relates to a conjugate which comprises an MRI contrast agent component comprising a nanoparticle, which nanoparticle comprises a metal or a metal compound, and a hypoxia targeting moiety which is conjugated to the MRI contrast agent component, especially wherein said nanoparticle comprises iron oxide and a biocompartible coating and wherein said hypoxia targeting moiety is a nitroimidazole. Also provided is the use of a said conjugate in a method of imaging a subject, a method of detecting hypoxia, and a method of evaluating the activity of a pharmaceutical. Said conjugate is also of use in diagnosis.
摘要翻译： 本发明涉及一种缀合物，其包含MRI造影剂组分，其包含纳米颗粒，该纳米颗粒包含金属或金属化合物，以及与MRI造影剂组分缀合的缺氧靶向部分，特别是其中所述纳米颗粒包含氧化铁和 生物相容性涂层，其中所述缺氧靶向部分是硝基咪唑。 还提供了在受试者成像方法中使用所述缀合物，检测缺氧的方法以及评估药物活性的方法。 所述缀合物也可用于诊断。
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公开(公告)号：WO2016083788A1
公开(公告)日：2016-06-02
申请号：PCT/GB2015/053565
申请日：2015-11-24
发明人： KONOPLEV, Ivan , BURT, Graeme
CPC分类号： H05H7/22 , H05H7/06 , H05H13/10 , H05H2007/227
摘要： A radio-frequency (RF) cavity apparatus (22) for accelerating charged particles comprises first and second cavity arms (24, 26). The first and second cavity arms (24, 26) have respective first and second axes of rotational symmetry (28, 30) and each cavity arm comprises at least one cell (32, 34; 36, 38). The first and second cavity arms (24, 26) are connected by a resonance coupler (40). The cell(s) (32, 34) of the first cavity arm (24) have an axial dimensional parameter that is equal to a corresponding axial dimensional parameter of the cell(s) (36, 38) of the second cavity arm (26), and the cell(s) (32, 34) of the first cavity arm (24) have at least one non-axial dimensional parameter that differs from corresponding non-axial dimensional parameter(s) of the cell(s) (36, 38) of the second cavity arm (26).
摘要翻译： 用于加速带电粒子的射频（RF）腔装置（22）包括第一和第二腔臂（24,26）。 第一和第二腔臂（24,26）具有相应的旋转对称的第一和第二轴线（28,30），并且每个空腔臂包括至少一个单元（32,34; 36,38）。 第一和第二腔臂（24,26）通过谐振耦合器（40）连接。 第一空腔臂（24）的单元（32,34）具有等于第二空腔臂（26）的单元（36,38）的对应的轴向尺寸参数的轴向尺寸参数 ），并且第一空腔臂（24）的单元（32,34）具有至少一个不同于单元（36）的非轴向尺寸参数的非轴向尺寸参数 ，38）。
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公开(公告)号：WO2016079511A1
公开(公告)日：2016-05-26
申请号：PCT/GB2015/053502
申请日：2015-11-18
发明人： SHEN, Licheng , HANKINS, Nicholas
IPC分类号： C02F1/56 , C02F1/58 , C02F1/68 , C11D1/14 , C11D1/40 , C11D3/37 , C02F1/54 , C08F226/04 , C02F101/10 , C02F101/16 , C02F101/20 , C02F101/22 , C02F101/30 , C02F103/10 , C02F103/30 , C02F103/16
CPC分类号： C02F1/56 , C02F1/547 , C02F1/683 , C02F2101/105 , C02F2101/163 , C02F2101/203 , C02F2101/206 , C02F2101/22 , C02F2101/306 , C02F2101/308 , C02F2103/10 , C02F2103/16 , C02F2103/30 , C02F2305/04 , C08F226/04 , Y02P20/582
摘要： The present invention relates to the use of a polymer comprising ionisable groups and an ionic surfactant to remove a charged species from solution.
摘要翻译： 本发明涉及包含可离子基团和离子表面活性剂的聚合物在溶液中除去带电物质的用途。
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公开(公告)号：WO2016075465A1
公开(公告)日：2016-05-19
申请号：PCT/GB2015/053427
申请日：2015-11-11
发明人： GRANT, Patrick , HUANG, Chun
IPC分类号： H01M4/04 , H01M4/133 , H01M4/139 , H01M4/1393 , H01M4/36 , H01G11/28 , H01G11/86 , H01M4/131
CPC分类号： H01M4/139 , H01G11/28 , H01G11/86 , H01M4/0404 , H01M4/131 , H01M4/133 , H01M4/366 , Y02E60/13
摘要： An electrode structure comprises a conductive substrate or current collector and a first layer comprising a first electrochemically active material, the first active material being characterized by one or more first electrochemical properties. A second layer comprises a second electrochemically active material, the second active material being characterized by one or more second electrochemical properties, at least one of which is different from said one or more first electrochemical properties. The first and second layers are provided at predefined locations within the electrode structure based on the respective first and second electrochemical properties of the first and second electrochemically active materials to maximise the performance of each of the first and second layers. A method of fabricating such an electrode structure is also provided.
摘要翻译： 电极结构包括导电基底或集电器和包含第一电化学活性材料的第一层，第一活性材料的特征在于一个或多个第一电化学特性。 第二层包括第二电化学活性材料，第二活性材料的特征在于一种或多种第二电化学性质，其中至少一种不同于所述一种或多种第一电化学性质。 基于第一和第二电化学活性材料的相应的第一和第二电化学特性，第一和第二层设置在电极结构内的预定位置处，以最大化第一和第二层中的每一个的性能。 还提供了制造这种电极结构的方法。
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公开(公告)号：WO2016067025A1
公开(公告)日：2016-05-06
申请号：PCT/GB2015/053232
申请日：2015-10-28
发明人： TSANG, Shik Chi Edman , XIA, Qineng
CPC分类号： C07C1/22 , B01J23/6484 , B01J23/6486 , B01J23/6525 , B01J23/6527 , B01J27/1856 , B01J27/188 , B01J27/19 , B01J27/195 , B01J27/285 , B01J35/1014 , B01J35/1019 , B01J37/0201 , B01J38/02 , B01J38/12 , C07C2523/42 , C07C2523/44 , C07C2527/195 , C10G3/50 , C10G45/62 , Y02P20/584 , Y02P30/20 , C07C9/15 , C07C9/22
摘要： The invention provides a process for producing a hydrocarbon, which process comprises contacting an organic compound comprising at least one heteroatom with hydrogen in the presence of a solid catalyst, which catalyst comprises: (a) a metal which is palladium, platinum, rhodium, iridium, ruthenium, silver, gold, nickel or copper; and (b) a compound comprising: (i) niobium, tantalum, molybdenum or tungsten; and (ii) oxygen. Further provided is a composition, and a catalyst. Both the compositionand the catalyst comprise (a) a metal which is palladium, platinum, rhodium, iridium, ruthenium, silver, gold, nickel or copper; and (b) a compound comprising: (i) niobium, tantalum, molybdenum or tungsten;and (ii) oxygen. The catalyst is typically a hydrogenolysis catalyst. Itmay for instance be employed as a hydrodeoxygenation (HDO), hydrodesulfurization (HDS) or hydrodenitrogenation(HDN) catalyst, and is usually employed as an HDO catalyst.
摘要翻译： 本发明提供一种生产烃的方法，该方法包括在固体催化剂存在下使包含至少一个杂原子的有机化合物与氢气接触，该催化剂包括：（a）金属，其为钯，铂，铑，铱 ，钌，银，金，镍或铜; 和（b）化合物，其包含：（i）铌，钽，钼或钨; 和（ii）氧气。 还提供了一种组合物和一种催化剂。 组合物和催化剂都包含（a）钯，铂，铑，铱，钌，银，金，镍或铜的金属; 和（b）包含：（i）铌，钽，钼或钨的化合物;和（ii）氧气。 催化剂通常是氢解催化剂。 例如可用作加氢脱氧（HDO），加氢脱硫（HDS）或加氢脱氮（HDN）催化剂，通常用作HDO催化剂。
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