公开(公告)号：WO2009128940A1

公开(公告)日：2009-10-22

申请号：PCT/US2009/002403

申请日：2009-04-17

Applicant: MIRAMAR LABS, INC. ,  KIM, Steven ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SALAMINI, Alexey ,  SU, Ted ,  CHUN, Dong, Hoon ,  BEN-HAIM, Yoav

Inventor： KIM, Steven ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SALAMINI, Alexey ,  SU, Ted ,  CHUN, Dong, Hoon ,  BEN-HAIM, Yoav

IPC: A61B18/18

CPC classification number: A61B18/1815 ,  A61B2017/00106 ,  A61B2018/00023 ,  A61B2018/00291 ,  A61B2018/00452 ,  A61N5/04

Abstract: The present invention is directed to systems, apparatus, methods and procedures for the noninvasive treatment of tissue, including treatment using microwave energy. In one embodiment of the invention a medical device and associated apparatus and procedures are used to treat dermatological conditions using, for example, microwave energy.

Abstract translation: 本发明涉及用于非侵入性处理组织的系统，装置，方法和程序，包括使用微波能量的处理。 在本发明的一个实施例中，使用医疗装置和相关联的装置和程序来使用例如微波能量来治疗皮肤病学病症。

公开(公告)号：WO2010096840A2

公开(公告)日：2010-08-26

申请号：PCT/US2010/025124

申请日：2010-02-23

Applicant: MIRAMAR LABS, INC. ,  KIM, Steven ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SALAMINI, Alexey ,  SU, Ted ,  CHUNG, Dong, Hoon ,  BEN-HAIM, Yoav ,  LOEW, Christopher

Inventor： KIM, Steven ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SALAMINI, Alexey ,  SU, Ted ,  CHUNG, Dong, Hoon ,  BEN-HAIM, Yoav ,  LOEW, Christopher

IPC: A61H7/00 ,  A61M1/00 ,  A61B5/00 ,  A61B5/04 ,  A61B5/05

CPC classification number: A61B18/18 ,  A61B18/1815 ,  A61B90/98 ,  A61B2017/306 ,  A61B2018/00005 ,  A61B2090/3937 ,  A61H9/0057 ,  A61H2201/10 ,  A61H2201/1685 ,  A61N5/02 ,  A61N5/04

Abstract: An applicator-tissue interface is disclosed for use in connection with medical device treatment applicators. The interface provides a cover to protect applicator components against contamination and may be disposable or reusable. Also included are tissue acquisition features including a tissue receiving chamber defined by a bio-barrier with vacuum ports or channels for tissue acquisition. Vacuum balancing is provided to prevent contamination on the applicator side of the bio-barrier. Locking mechanisms are disclosed for ensuring secure attachment between the interface and applicator. Methods of using the applicator-tissue interface in connection with an applicator are also disclosed.

Abstract translation: 公开了一种与医疗器械治疗敷料器结合使用的涂抹器 - 组织界面。 界面提供了一个保护涂料组件免受污染的盖子，可以是一次性的或可重复使用的。 还包括组织采集特征，包括由具有用于组织采集的真空端口或通道的生物屏障限定的组织接收室。 提供真空平衡以防止生物屏障的施用器侧的污染。 公开了锁定机构以确保接口和施加器之间的牢固连接。 还公开了与施用器相关地使用施用器 - 组织界面的方法。

公开(公告)号：WO2013019785A1

公开(公告)日：2013-02-07

申请号：PCT/US2012/048957

申请日：2012-07-31

Applicant: MIRAMAR LABS, INC. ,  BEN-HAIM, Yoav ,  BENTLEY, Peter, J. ,  CHUN, Dong, Hoon ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SHAN, Kevin ,  SU, Ted ,  KIM, Steven

Inventor： BEN-HAIM, Yoav ,  BENTLEY, Peter, J. ,  CHUN, Dong, Hoon ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SHAN, Kevin ,  SU, Ted ,  KIM, Steven

IPC: A61B18/18

CPC classification number: A61B18/1815 ,  A61B2018/00023 ,  A61B2018/00172 ,  A61B2018/00291 ,  A61B2018/00452 ,  A61B2018/00464 ,  A61B2018/0047 ,  A61B2018/00476

Abstract: An tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Abstract translation: 组织接口模块在组织接口模块的近侧具有施用室，在组织接口模块的远端侧具有组织采集室。 施用器室可以包括：适于接收施用器的开口; 定位在所述施用器腔室中并适于将所述组织界面模块附接到所述施用器的附接机构; 位于所述施用器腔室的近侧的密封构件; 以及位于所述施用器腔室的近侧的真空接口，并且适于接纳位于所述施用器的远端上的真空入口。 本发明还包括相应的方法。

公开(公告)号：WO2010096840A3

公开(公告)日：2011-01-20

申请号：PCT/US2010025124

申请日：2010-02-23

Applicant: MIRAMAR LABS INC ,  KIM STEVEN ,  FRANCIS DANIEL ,  JOHNSON JESSI E ,  SALAMINI ALEXEY ,  SU TED ,  CHUNG DONG HOON ,  BEN-HAIM YOAV ,  LOEW CHRISTOPHER

Inventor： KIM STEVEN ,  FRANCIS DANIEL ,  JOHNSON JESSI E ,  SALAMINI ALEXEY ,  SU TED ,  CHUNG DONG HOON ,  BEN-HAIM YOAV ,  LOEW CHRISTOPHER

IPC: A61H7/00 ,  A61B5/00 ,  A61B5/04 ,  A61B5/05 ,  A61M1/00

CPC classification number: A61B18/18 ,  A61B18/1815 ,  A61B90/98 ,  A61B2017/306 ,  A61B2018/00005 ,  A61B2090/3937 ,  A61H9/0057 ,  A61H2201/10 ,  A61H2201/1685 ,  A61N5/02 ,  A61N5/04

Abstract: An applicator-tissue interface is disclosed for use in connection with medical device treatment applicators. The interface provides a cover to protect applicator components against contamination and may be disposable or reusable. Also included are tissue acquisition features including a tissue receiving chamber defined by a bio-barrier with vacuum ports or channels for tissue acquisition. Vacuum balancing is provided to prevent contamination on the applicator side of the bio-barrier. Locking mechanisms are disclosed for ensuring secure attachment between the interface and applicator. Methods of using the applicator-tissue interface in connection with an applicator are also disclosed.

Abstract translation: 公开了一种与医疗器械治疗敷料器结合使用的涂抹器 - 组织界面。 界面提供了一个保护涂料组件免受污染的盖子，可以是一次性的或可重复使用的。 还包括组织采集特征，包括由具有用于组织采集的真空端口或通道的生物屏障限定的组织接收室。 提供真空平衡以防止生物屏障的施用器侧的污染。 公开了锁定机构以确保接口和施加器之间的牢固连接。 还公开了与施用器相关地使用施用器 - 组织界面的方法。

公开(公告)号：WO2013019796A1

公开(公告)日：2013-02-07

申请号：PCT/US2012/048999

申请日：2012-07-31

Applicant: MIRAMAR LABS, INC. ,  BEN-HAIM, Yoav ,  BENTLEY, Peter, J. ,  CHUN, Dong Hoon ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SHAN, Kevin ,  SU, Ted ,  KIM, Steven

Inventor： BEN-HAIM, Yoav ,  BENTLEY, Peter, J. ,  CHUN, Dong Hoon ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SHAN, Kevin ,  SU, Ted ,  KIM, Steven

IPC: A61B18/18

CPC classification number: A61N5/04 ,  A61B18/1815 ,  A61B2018/00452 ,  A61N5/022

Abstract: A dermatological energy applicator and tissue interface module are provided which may include any number of features. The dermatological energy applicator can be configured to apply microwave energy to tissue to treat conditions of the skin, including hyperhidrosis or excessive sweating. The energy applicator can further include a cooling element and vacuum ports. The tissue interface module can include an applicator chamber adapted to receive the energy applicator, and can further include a tissue acquisition chamber adapted to engage tissue, a bio-barrier configured to prevent passage of gas and liquid, and a filter disposed between the applicator chamber and the tissue acquisition chamber configured to prevent passage of gas but prevent passage of liquid.

Abstract translation: 提供了皮肤能量施加器和组织接口模块，其可以包括任何数量的特征。 皮肤能量施加器可以被配置为将微波能量施加到组织以治疗皮肤的状况，包括多汗症或过度出汗。 能量施加器还可包括冷却元件和真空端口。 组织接口模块可以包括适于接收能量施加器的施用器室，并且还可以包括适于接合组织的组织采集室，被配置为防止气体和液体通过的生物屏障以及设置在施用器室 并且所述组织采集室被配置为防止气体通过，但是防止液体通过。

公开(公告)号：WO2010047818A1

公开(公告)日：2010-04-29

申请号：PCT/US2009/005772

申请日：2009-10-22

Applicant: MIRAMAR LABS, INC. ,  KIM, Steven ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SALAMINI, Alexey ,  SU, Ted ,  CHUNG, Dong, Hoon ,  BEN-HAIM, Yoav ,  LOEW, Christopher ,  KOPELOW, Leo ,  CHEW, Sunmi

Inventor： KIM, Steven ,  FRANCIS, Daniel ,  JOHNSON, Jessi, E. ,  SALAMINI, Alexey ,  SU, Ted ,  CHUNG, Dong, Hoon ,  BEN-HAIM, Yoav ,  LOEW, Christopher ,  KOPELOW, Leo ,  CHEW, Sunmi

IPC: A61H1/00

CPC classification number: A61B18/18 ,  A61B18/1815 ,  A61B2017/00115 ,  A61B2017/00199 ,  A61B2017/00477 ,  A61B2017/306 ,  A61B2018/00023 ,  A61B2018/00702 ,  A61B2018/183 ,  A61B2034/252 ,  A61B2034/254 ,  A61B2090/372 ,  A61H9/0057 ,  A61N5/02

Abstract: A system applies, in a non- invasive manner, energy to a targeted tissue region employing a controlled source of energy, a multiple use applicator, and a single use, applicator- tissue interface carried by the applicator. The system can generate and apply energy in a controlled fashion to form a predefined pattern of lesions that provide therapeutic benefit, e.g., to moderate or interrupt function of the sweat glands in the underarm (axilla).

Abstract translation: 系统以非侵入性的方式将能量应用于使用受控的能量源，多用途施用器和由施用器承载的单次使用的施用器 - 组织界面的目标组织区域。 该系统可以以受控的方式产生和施加能量，以形成提供治疗益处的预定模式的病变，例如在腋下（腋窝）中的汗腺的中度或中断功能。