-
公开(公告)号：WO2011031423A2
公开(公告)日：2011-03-17
申请号：PCT/US2010/045921
申请日：2010-08-18
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , GADA, Manish, B. , KLEINER, Lothar, W. , STEICHEN, Bethany, E.
Inventor： GADA, Manish, B. , KLEINER, Lothar, W. , STEICHEN, Bethany, E.
IPC: A61F2/82
CPC classification number: A61L31/06 , A61F2/82 , A61F2210/0004 , A61L31/14 , B29C47/0023 , B29C47/0026 , B29C47/0035 , B29C47/28 , B29C47/38 , B29C47/702 , B29L2031/7542 , C08L67/04
Abstract: Methods of fabricating a low crystallinity polymer tube for polymers subject to strain-induced crystallization. The low crystallinity tube may be further processed to make an implantable medical device.
Abstract translation: 制造用于应变诱导结晶的聚合物的低结晶度聚合物管的方法。 可以进一步处理低结晶度管以制造可植入的医疗装置。
-
2.发明申请FABRICATING AN IMPLANTABLE MEDICAL DEVICE FROM AN AMORPHOUS OR VERY LOW CRYSTALLINITY POLYMER CONSTRUCT 审中-公开从非晶或非常低结晶度聚合物结构制造可植入医疗装置
公开(公告)号：WO2011002554A3
公开(公告)日：2011-03-17
申请号：PCT/US2010034077
申请日：2010-05-07
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS , WANG YUNBING , KLEINER LOTHAR W
Inventor： WANG YUNBING , KLEINER LOTHAR W
CPC classification number: B29D23/00 , A61L31/06 , A61L31/14 , B29C71/0063 , C08L67/04
Abstract: Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing, nucleating agents, or both are disclosed herein. A polymeric construct that is completely amorphous or that has a very low crystallinity is annealed with no or substantially no crystal growth to increase nucleation density. Alternatively, the polymer construct includes nucleating agent. The crystallinity of the polymer construct is increased with a high nucleation density through an increase in temperature, deformation, or both. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the increase in crystallinity.
Abstract translation: 本文公开了通过退火，成核剂或二者制造具有改善的断裂韧性的聚合物可植入装置的方法。 完全无定形或具有非常低的结晶度的聚合物构造体退火，没有或基本没有晶体生长以增加成核密度。 或者，聚合物构建体包含成核剂。 通过温度升高，变形或两者的增加，高成核密度增加了聚合物构造的结晶度。 可植入的医疗装置，例如支架，可以在增加结晶度后由聚合物构建体制造。
-
3.发明申请IMPLANTABLE DRUG DELIVERY DEVICES HAVING ALTERNATING HYDROPHILIC AND AMPHIPHILIC POLYMER LAYERS 审中-公开具有替代氢化和高分子聚合物层的可植入药物递送装置
公开(公告)号：WO2009148777A2
公开(公告)日：2009-12-10
申请号：PCT/US2009/043650
申请日：2009-05-12
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , HOSSAINY, Syed, F. A. , TROLLSAS, Mikael, O. , KLEINER, Lothar, W.
Inventor： HOSSAINY, Syed, F. A. , TROLLSAS, Mikael, O. , KLEINER, Lothar, W.
CPC classification number: A61L31/10 , A61L31/148 , A61L2420/08 , Y10T428/31551 , Y10T428/31562 , Y10T428/31591 , Y10T428/31736 , Y10T428/3175 , Y10T428/31786 , Y10T428/3179 , Y10T428/31855 , Y10T428/31891
Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
Abstract translation: 公开了具有交替的亲水和两亲性聚合物层的可植入药物递送医疗装置和用于治疗血管疾病的方法。
-
4.发明申请METHODS, COMPOSITIONS AND DEVICES FOR TREATING LEASIONED SITES USING BIOABSORBABLE CARRIERS 审中-公开方法，组合物和使用生物载体处理租赁场地的设备
公开(公告)号：WO2008088456A3
公开(公告)日：2008-10-23
申请号：PCT/US2007024304
申请日：2007-11-20
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS , KLEINER LOTHAR W , HOSSAINY SYED , ASTAFIEVA IRINA , PACETTI STEPHEN , GLAUSER THIERRY , DESNOYER JESSICA , LUDWIG FLORIAN N
Inventor： KLEINER LOTHAR W , HOSSAINY SYED , ASTAFIEVA IRINA , PACETTI STEPHEN , GLAUSER THIERRY , DESNOYER JESSICA , LUDWIG FLORIAN N
CPC classification number: A61K9/143 , A61K9/0019 , A61K9/1611 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/00 , C08L67/04
Abstract: Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device. Implantable medical devices manufactured with coatings including the particles or embedded within the medical device are additionally disclosed.
Abstract translation: 公开了用于持续释放治疗剂以治疗闭塞的血管和受影响的组织和/或器官的方法和组合物。 多孔或无孔生物可吸收玻璃，金属或陶瓷珠，棒或纤维颗粒可以加载处理剂和任选的图像增强剂，并涂覆有持续释放的涂层以递送至闭塞的血管并受影响 组织和/或器官。 另外公开了用包括颗粒的涂层制造的植入式医疗装置或嵌入在医疗装置内的植入式医疗装置。
-
5.发明申请METHODS, COMPOSITIONS AND DEVICES FOR TREATING LEASIONED SITES USING BIOABSORBABLE CARRIERS 审中-公开使用可生物吸收载体治疗潜在部位的方法，组合物和装置
公开(公告)号：WO2008088456A2
公开(公告)日：2008-07-24
申请号：PCT/US2007/024304
申请日：2007-11-20
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , KLEINER, Lothar, W. , HOSSAINY, Syed , ASTAFIEVA, Irina , PACETTI, Stephen , GLAUSER, Thierry , DESNOYER, Jessica , LUDWIG, Florian, N.
Inventor： KLEINER, Lothar, W. , HOSSAINY, Syed , ASTAFIEVA, Irina , PACETTI, Stephen , GLAUSER, Thierry , DESNOYER, Jessica , LUDWIG, Florian, N.
CPC classification number: A61K9/143 , A61K9/0019 , A61K9/1611 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/00 , C08L67/04
Abstract: Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device. Implantable medical devices manufactured with coatings including the particles or embedded within the medical device are additionally disclosed.
Abstract translation: 公开了用于持续释放治疗剂以治疗闭塞血管和受影响的组织和/或器官的方法和组合物。 多孔或无孔生物可吸收玻璃，金属或陶瓷珠，棒或纤维颗粒可装载处理剂和任选的图像增强剂，并涂有缓释包衣以递送至闭塞血管并受影响 组织和/或器官通过递送装置。
-
Patent Agency Ranking
公开(公告)号：WO2008076731A2
公开(公告)日：2008-06-26
申请号：PCT/US2007/087151
申请日：2007-12-12
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , TROLLSAS, Mikael, O. , NGO, Michael, Huy , MASLANKA, Bozena, Zofia , HOSSAINY, Syed Faiyaz, Ahmed , KLEINER, Lothar, W.
Inventor： TROLLSAS, Mikael, O. , NGO, Michael, Huy , MASLANKA, Bozena, Zofia , HOSSAINY, Syed Faiyaz, Ahmed , KLEINER, Lothar, W.
CPC classification number: A61L31/10 , A61F2/82 , A61L27/34 , A61L27/54 , A61L27/58 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , C09D143/02
Abstract: A coating of fast absorption or fast dissolution on an implantable device and methods of making and using of the coating are provided.
Abstract translation: 提供了在可植入装置上快速吸收或快速溶解的涂层以及制备和使用涂层的方法。
-
公开(公告)号：WO2007123872A3
公开(公告)日：2008-03-13
申请号：PCT/US2007009290
申请日：2007-04-13
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS , KLEINER LOTHAR W , HOSSAINY SYED , PACETTI STEPHEN , DESNOYER JESSICA
Inventor： KLEINER LOTHAR W , HOSSAINY SYED , PACETTI STEPHEN , DESNOYER JESSICA
CPC classification number: A61K47/48207 , A61K9/0024 , A61K9/08 , A61K9/10 , A61K31/337 , A61K31/4745 , A61K31/727 , A61K47/34 , A61K47/593 , A61K47/595 , A61K47/60 , C08L77/12 , C08L2205/02 , C08L2666/20
Abstract: A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the therapeutic agent delivery system by delivering the therapeutic agent delivery system formed of a PEA polymer, a therapeutic agent, and a water miscible solvent to a physiological environment and separating the phase of the therapeutic agent delivery system to form a membrane from the polymer to contain the therapeutic agent within the physiological environment is also described. Additionally disclosed is a kit including a syringe and a therapeutic agent delivery system within the syringe.
Abstract translation: 本文描述了由特定类型的聚（酯酰胺）（PEA），治疗剂和水混溶性溶剂形成的治疗剂递送系统。 通过将由PEA聚合物，治疗剂和水混溶性溶剂形成的治疗剂递送系统递送到生理环境来递送治疗剂递送系统的方法，并分离治疗剂递送系统的相以形成膜 还描述了在生理环境中含有治疗剂的聚合物。 另外公开了一种试剂盒，其包括注射器内的注射器和治疗剂递送系统。
-
公开(公告)号：WO2007123872A2
公开(公告)日：2007-11-01
申请号：PCT/US2007/009290
申请日：2007-04-13
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS, INC. , KLEINER, Lothar, W. , HOSSAINY, Syed , PACETTI, Stephen , DESNOYER, Jessica
Inventor： KLEINER, Lothar, W. , HOSSAINY, Syed , PACETTI, Stephen , DESNOYER, Jessica
CPC classification number: A61K47/48207 , A61K9/0024 , A61K9/08 , A61K9/10 , A61K31/337 , A61K31/4745 , A61K31/727 , A61K47/34 , A61K47/593 , A61K47/595 , A61K47/60 , C08L77/12 , C08L2205/02 , C08L2666/20
Abstract: A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the therapeutic agent delivery system by delivering the therapeutic agent delivery system formed of a PEA polymer, a therapeutic agent, and a water miscible solvent to a physiological environment and separating the phase of the therapeutic agent delivery system to form a membrane from the polymer to contain the therapeutic agent within the physiological environment is also described. Additionally disclosed is a kit including a syringe and a therapeutic agent delivery system within the syringe.
Abstract translation: 本文描述了由特定类型的聚（酯酰胺）（PEA），治疗剂和水混溶性溶剂形成的治疗剂递送系统。 通过将由PEA聚合物，治疗剂和水混溶性溶剂形成的治疗剂递送系统递送到生理环境来递送治疗剂递送系统的方法，并分离治疗剂递送系统的相以形成膜 还描述了在生理环境中含有治疗剂的聚合物。 另外公开了一种试剂盒，其包括注射器内的注射器和治疗剂递送系统。
-
9.发明申请FABRICATING AN IMPLANTABLE MEDICAL DEVICE FROM AN AMORPHOUS OR VERY LOW CRYSTALLINITY POLYMER CONSTRUCT 审中-公开从不规则或非常低的结晶聚合物构造制造可植入医疗器械
公开(公告)号：WO2011002554A2
公开(公告)日：2011-01-06
申请号：PCT/US2010/034077
申请日：2010-05-07
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , WANG, Yunbing , KLEINER, Lothar W.
Inventor： WANG, Yunbing , KLEINER, Lothar W.
IPC: A61L31/06
CPC classification number: B29D23/00 , A61L31/06 , A61L31/14 , B29C71/0063 , C08L67/04
Abstract: Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing, nucleating agents, or both are disclosed herein. A polymeric construct that is completely amorphous or that has a very low crystallinity is annealed with no or substantially no crystal growth to increase nucleation density. Alternatively, the polymer construct includes nucleating agent. The crystallinity of the polymer construct is increased with a high nucleation density through an increase in temperature, deformation, or both. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the increase in crystallinity.
Abstract translation: 本文公开了通过退火，成核剂或两者制造具有改善的断裂韧性的聚合物可植入装置的方法。 完全无定形或具有非常低的结晶度的聚合物结构退火，没有或基本上没有晶体生长以增加成核密度。 或者，聚合物构造物包括成核剂。 聚合物构造物的结晶度随着温度，变形或两者的增加而以较高的成核密度增加。 在结晶度增加之后，可由聚合物构造体制造可植入的医疗装置，例如支架。
-
10.发明申请TUBE EXPANSION PROCESS FOR SEMICRYSTALLINE POLYMERS TO MAXIMIZE FRACTURE TOUGHNESS 审中-公开用于半结晶聚合物的管扩张过程以最大限度地破裂韧性
公开(公告)号：WO2010017090A2
公开(公告)日：2010-02-11
申请号：PCT/US2009/052267
申请日：2009-07-30
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , KLEINER, Lothar, W. , OBERHAUSER, James, P. , GLAUSER, Thierry , WROLSTAD, David, K. , WANG, Yunbing
Inventor： KLEINER, Lothar, W. , OBERHAUSER, James, P. , GLAUSER, Thierry , WROLSTAD, David, K. , WANG, Yunbing
CPC classification number: B29C61/04 , B29C35/045 , B29C35/0805 , B29C71/0063 , B29C71/02 , B29C2035/0822 , B29C2071/022 , B29K2067/046 , B29K2105/258 , B29K2995/004 , B29K2995/006 , B29K2995/0089 , B29L2031/7534
Abstract: Methods of fabricating a polymeric stent with improved fracture toughness including radial expansion of a polymer tube along its entire length at the same time and fabricating a stent from the expanded tube are disclosed herein.
Abstract translation: 本文公开了制造具有改进的断裂韧性的聚合物支架的方法，包括聚合物管同时沿其整个长度的径向膨胀并且从膨胀管制造支架。
-
-
-
-
-
-
-
-
-
Search Results
28
records
(took 0.018 seconds)
