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公开(公告)号：WO2010101722A2
公开(公告)日：2010-09-10
申请号：PCT/US2010/024827
申请日：2010-02-19
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , LUDWIG, Florian, N. , STANKUS, John , TROLLSAS, Mikael
Inventor： LUDWIG, Florian, N. , STANKUS, John , TROLLSAS, Mikael
IPC: A61L31/10
CPC classification number: A61L31/10 , A61K31/436 , A61K47/32 , A61L29/085 , A61L31/16 , A61L33/06 , C08F220/28 , Y10T428/31935
Abstract: A polymer comprising a phosphoryl choline moiety(ies), a composition comprising the polymer and optionally a bioactive agent, an implantable device such as a DES or a non-implantable device such as an angioplasty balloon comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided.
Abstract translation: 包含磷酰胆碱部分的聚合物，包含聚合物和任选的生物活性剂的组合物，可植入装置例如DES或非可植入装置，例如血管成形术球囊，其上包括包含聚合物的涂层和任选的 提供了生物活性剂，以及使用该装置来治疗人的病症的方法。
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2.发明申请NANOPARTICLE-COATED MEDICAL DEVICES AND FORMULATIONS FOR TREATING VASCULAR DISEASE 审中-公开用于治疗血管疾病的纳米涂层医疗装置和制剂
公开(公告)号：WO2009025926A2
公开(公告)日：2009-02-26
申请号：PCT/US2008/067015
申请日：2008-06-13
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , LUDWIG, Florian, N. , HOSSAINY, Syed, F., A. , MURASE, Katsuyuki , ZHAO, Li , ASTAFIEVA, Irina
Inventor： LUDWIG, Florian, N. , HOSSAINY, Syed, F., A. , MURASE, Katsuyuki , ZHAO, Li , ASTAFIEVA, Irina
CPC classification number: A61L31/10 , A61K9/1075 , A61K9/127 , A61K9/51 , A61L31/16 , A61L2300/624 , A61L2300/626 , A61L2400/12
Abstract: Nanoparticle-coated medical devices, nanoparticle-containing formulations and methods of using for treating a vascular disease are disclosed.
Abstract translation: 公开了纳米颗粒涂覆的医疗装置，含纳米颗粒的制剂和用于治疗血管疾病的方法。
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公开(公告)号：WO2008151299A3
公开(公告)日：2008-12-11
申请号：PCT/US2008/065981
申请日：2008-06-05
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , KRAMER-BROWN, Pamela, A. , GALE, David, C. , KLEINER, Lothar, Walter , ASTAFIEVA, Irina , CHIU, Jessica , LUDWIG, Florian, N.
Inventor： KRAMER-BROWN, Pamela, A. , GALE, David, C. , KLEINER, Lothar, Walter , ASTAFIEVA, Irina , CHIU, Jessica , LUDWIG, Florian, N.
Abstract: Implantable medical devices adapted to erodibly release delivery media for local and regional treatment are disclosed.
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公开(公告)号：WO2008144146A1
公开(公告)日：2008-11-27
申请号：PCT/US2008/061050
申请日：2008-04-21
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS, INC. , EL-NOUNOU, Fozan, O. , LUDWIG, Florian, N. , HOSSAINY, Syed Faiyaz, Ahmed , CONSIGNY, Paul
Inventor： EL-NOUNOU, Fozan, O. , LUDWIG, Florian, N. , HOSSAINY, Syed Faiyaz, Ahmed , CONSIGNY, Paul
IPC: A61M25/00
CPC classification number: A61M25/0082 , A61M25/01 , A61M2025/0004 , A61M2025/0073 , A61M2206/11
Abstract: Catheters (110) with laminar flow bioactive agent delivery properties.
Abstract translation: 导管（110）具有层流生物活性剂输送性能。
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公开(公告)号：WO2008109230A2
公开(公告)日：2008-09-12
申请号：PCT/US2008/053707
申请日：2008-02-12
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , LUDWIG, Florian, N. , HOSSAINY, Syed Faiyaz, Ahmed , PACETTI, Stephen, D.
CPC classification number: A61K9/0087 , A61K47/6907 , A61K47/6911 , A61K47/6913 , A61K47/6915 , A61K47/6935 , B82Y5/00
Abstract: A composition that includes nanoparticles with binding affinity for platelets, and methods for using this composition to treat vascular disease are disclosed.
Abstract translation: 公开了一种包含对血小板具有结合亲和力的纳米颗粒的组合物，以及使用该组合物治疗血管疾病的方法。
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Patent Agency Ranking
公开(公告)号：WO2008076847A3
公开(公告)日：2008-06-26
申请号：PCT/US2007/087487
申请日：2007-12-13
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC. , PACETTI, Stephen, D. , CONSIGNY, Paul , HEIL, Ronald, W. , LUDWIG, Florian, N. , DAVALIAN, Dariush , ZHAO, Li , ASTAFIEVA, Irina , WAN, Jinping , EL-NOUNOU, Fozan , MURASE, Katsuyuki , HOSSAINY, Syed, Faiyaz Ahmed , BRIGHT, Rachel , ELLIS, Jeffrey
Inventor： PACETTI, Stephen, D. , CONSIGNY, Paul , HEIL, Ronald, W. , LUDWIG, Florian, N. , DAVALIAN, Dariush , ZHAO, Li , ASTAFIEVA, Irina , WAN, Jinping , EL-NOUNOU, Fozan , MURASE, Katsuyuki , HOSSAINY, Syed, Faiyaz Ahmed , BRIGHT, Rachel , ELLIS, Jeffrey
Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
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公开(公告)号：WO2008031097A1
公开(公告)日：2008-03-13
申请号：PCT/US2007/078035
申请日：2007-09-10
Inventor： KRAMER-BROWN, Pamela A. , LUDWIG, Florian N.
IPC: A61F2/06
CPC classification number: A61F2/92 , A61F2250/0067
Abstract: A bioactive agent-containing implantable open ring-shaped medical device and methods of using for the treatment of disease are disclosed.
Abstract translation: 公开了一种含生物活性剂的可植入开环形医疗装置及其用于治疗疾病的方法。
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8.发明申请METHODS, COMPOSITIONS AND DEVICES FOR TREATING LESIONED SITES USING BIOABSORBABLE CARRIERS 审中-公开方法，组合物和使用生物可降解载体处理裂解位点的装置
公开(公告)号：WO2007133382A3
公开(公告)日：2008-01-10
申请号：PCT/US2007009526
申请日：2007-04-18
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS , KLEINER LOTHAR W , HOSSAINY SYED , ASTAFIEVA IRINA , PACETTI STEPHEN , GLAUSER THIERRY , DESNOYER JESSICA , LUDWIG FLORIAN N
Inventor： KLEINER LOTHAR W , HOSSAINY SYED , ASTAFIEVA IRINA , PACETTI STEPHEN , GLAUSER THIERRY , DESNOYER JESSICA , LUDWIG FLORIAN N
CPC classification number: A61K9/0019 , A61K9/143 , A61K9/1611 , A61L31/148 , A61L31/16 , A61L2300/602
Abstract: Methods and compositions for the sustained release of treatment agents to treat an occluded blood vessel and affected tissue and/or organs are disclosed. Porous or non-porous bioabsorbable glass, metal or ceramic bead, rod or fiber particles can be loaded with a treatment agent, and optionally an image-enhancing agent, and coated with a sustained-release coating for delivery to an occluded blood vessel and affected tissue and/or organs by a delivery device.
Abstract translation: 公开了用于持续释放治疗剂以治疗闭塞的血管和受影响的组织和/或器官的方法和组合物。 多孔或无孔生物可吸收玻璃，金属或陶瓷珠，棒或纤维颗粒可以加载处理剂和任选的图像增强剂，并涂覆有持续释放的涂层以递送至闭塞的血管并受影响 组织和/或器官通过递送装置。
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公开(公告)号：WO2010101722A3
公开(公告)日：2011-04-07
申请号：PCT/US2010024827
申请日：2010-02-19
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS , LUDWIG FLORIAN N , STANKUS JOHN , TROLLSAS MIKAEL
Inventor： LUDWIG FLORIAN N , STANKUS JOHN , TROLLSAS MIKAEL
CPC classification number: A61L31/10 , A61K31/436 , A61K47/32 , A61L29/085 , A61L31/16 , A61L33/06 , C08F220/28 , Y10T428/31935
Abstract: A polymer comprising a phosphoryl choline moiety(ies), a composition comprising the polymer and optionally a bioactive agent, an implantable device such as a DES or a non-implantable device such as an angioplasty balloon comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided.
Abstract translation: 包含磷酰胆碱部分的聚合物，包含聚合物和任选的生物活性剂的组合物，可植入装置例如DES或非可植入装置，例如血管成形术球囊，其上包括包含聚合物的涂层和任选的 提供了生物活性剂，以及使用该装置来治疗人的病症的方法。
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公开(公告)号：WO2008151299A2
公开(公告)日：2008-12-11
申请号：PCT/US2008065981
申请日：2008-06-05
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS , KRAMER-BROWN PAMELA A , GALE DAVID C , KLEINER LOTHAR WALTER , ASTAFIEVA IRINA , CHIU JESSICA , LUDWIG FLORIAN N
Inventor： KRAMER-BROWN PAMELA A , GALE DAVID C , KLEINER LOTHAR WALTER , ASTAFIEVA IRINA , CHIU JESSICA , LUDWIG FLORIAN N
CPC classification number: A61L31/10 , A61L31/088 , A61L31/127 , A61L31/14 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/604 , A61L2300/608 , A61L2300/624 , A61L2400/12
Abstract: Implantable medical devices adapted to erodibly release delivery media for local and regional treatment are disclosed.
Abstract translation: 公开了适用于本地和区域处理的适用于可释放释放输送介质的可植入医疗装置。
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