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    NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES
    1.
    发明申请
    NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES 审中-公开
    具有增强皮肤渗透性，细胞摄取和肿瘤递送特性的纳米颗粒

    公开(公告)号：WO2011090349A9

    公开(公告)日：2012-03-08

    申请号：PCT/KR2011000449

    申请日：2011-01-21

    Applicant: KWANGJU INST SCI & TECH ,  TAE GI YOONG ,  CHOI WON IL ,  KIM YOUNG HA ,  KIM JA-YOUNG ,  LEE JONG HYUN

    Inventor： TAE GI YOONG ,  CHOI WON IL ,  KIM YOUNG HA ,  KIM JA-YOUNG ,  LEE JONG HYUN

    IPC: A61K47/48 ,  A61K9/20 ,  A61K9/48 ,  A61K47/30 ,  A61K49/08 ,  A61P35/00

    CPC classification number: A61K9/0014 ,  A61K47/61

    Abstract: The present invention relates to a biopolymer-modified nanocarrier in which chitosan is bound to a water-soluble biocompatible polymer that has been crosslinked via a photo-crosslinkable functional group; wherein the chitosan-modified nanocarrier has a diameter which changes in accordance with changes in temperature, has enhanced skin permeability or cellular uptake and selective delivery to cancer tissue as compared with a bare nanocarrier to which chitosan has not been bound, and exhibits characteristics that are advantageous in photothermal therapy. The chitosan-modified nanocarrier of the present invention exhibits highly superior efficacy as a transdermal carrier, since the skin permeability is enhanced to a very suppressing level as compared with a bare nanocarrier that has no chitosan. The chitosan-modified nanocarrier of the present invention can be used to very great advantage in the imaging and photothermal therapy of tumour cells and cancer cells, since the cellular uptake by tumour cells and cancer cells is substantially improved.

    Abstract translation: 本发明涉及生物聚合物改性的纳米载体，其中壳聚糖与已经通过光交联官能团交联的水溶性生物相容性聚合物结合; 其中壳聚糖修饰的纳米载体具有根据温度变化而变化的直径，与未结合壳聚糖的裸纳米载体相比具有增强的皮肤渗透性或细胞摄取和选择性递送至癌组织，并且具有以下特征： 有利于光热治疗。 本发明的脱乙酰壳多糖修饰的纳米载体作为透皮载体具有高度优异的功效，因为与不含壳聚糖的裸纳米载体相比，皮肤渗透性提高到非常低的抑制水平。 本发明的壳聚糖修饰的纳米载体可以用于肿瘤细胞和癌细胞的成像和光热治疗中的非常大的优点，因为肿瘤细胞和癌细胞的细胞摄取被显着改善。

    MOBILE TERMINAL AND INTERFACE METHOD THEREOF
    3.
    发明申请
    MOBILE TERMINAL AND INTERFACE METHOD THEREOF 审中-公开
    移动终端及其接口方法

    公开(公告)号：WO2012128486A3

    公开(公告)日：2013-01-03

    申请号：PCT/KR2012001610

    申请日：2012-03-05

    Applicant: SAMSUNG ELECTRONICS CO LTD ,  LEE JONG HYUN

    Inventor： LEE JONG HYUN

    IPC: H04W88/02 ,  H01R27/00 ,  H02J7/00

    CPC classification number: H02J7/0044 ,  G06F1/26 ,  G06F11/3485 ,  G06F13/382 ,  H02J3/008 ,  H02J7/0008 ,  H02J7/0027 ,  H02J7/0047 ,  H04M1/0274 ,  H04M1/72527

    Abstract: A mobile terminal and an interface method thereof for connecting external devices, such as an adapter, a Universal Serial Bus (USB) cable, a docking station, an accessory, and the like, to the mobile terminal are provided. The mobile terminal includes a battery, a connector including a pin for data communication and first and second power pins for charging the battery, a memory for storing a reference voltage indicating a dedicated adapter of the battery, and a controller for receiving a voltage input from the first and second power pins, for recognizing an external device connected with the connector as the dedicated adapter when a voltage input from the pin for data communication is the reference voltage, and for charging the battery with power input to the first and second power pins.

    Abstract translation: 提供了一种用于将诸如适配器，通用串行总线（USB）电缆，对接站，附件等的外部设备连接到移动终端的移动终端及其接口方法。 移动终端包括电池，包括用于数据通信的引脚和用于对电池充电的第一和第二电源引脚的连接器，用于存储指示电池的专用适配器的参考电压的存储器，以及用于接收来自电池的电压输入的控制器 所述第一和第二电源引脚用于当从所述用于数据通信的引脚输入的电压为参考电压时识别与所述连接器连接的外部设备作为所述专用适配器，并且用于对所述电池充电以对所述第一和第二电源引脚 。

    TIN/TIN ALLOY NANOPARTICLE HAVING LOW MELTING TEMPERATURE AND METHOD FOR MANUFACTURING SAME
    4.
    发明申请
    TIN/TIN ALLOY NANOPARTICLE HAVING LOW MELTING TEMPERATURE AND METHOD FOR MANUFACTURING SAME 审中-公开
    具有低熔点温度的TIN / TIN合金纳米颗粒及其制造方法

    公开(公告)号：WO2012096489A3

    公开(公告)日：2012-11-29

    申请号：PCT/KR2012000223

    申请日：2012-01-10

    Applicant: ISP CO LTD ,  KIM YOUNG SANG ,  CHO KYUNG JIN ,  JANG SEOK PIL ,  LEE JONG HYUN ,  KIM HYUN SOO

    Inventor： KIM YOUNG SANG

    IPC: B22F1/00 ,  B23K35/26 ,  C25C5/02

    CPC classification number: C25C5/02 ,  B22F1/0018 ,  B22F2999/00 ,  B23K1/0016 ,  B23K35/0244 ,  B23K35/025 ,  B23K35/262 ,  B82Y30/00 ,  C25C1/14 ,  H01L24/11 ,  H01L24/13 ,  H01L2224/11332 ,  H01L2224/11505 ,  H01L2224/131 ,  H01L2924/00013 ,  H01L2924/01029 ,  H01L2924/01322 ,  B22F2301/30 ,  H01L2224/13099 ,  H01L2224/13599 ,  H01L2224/05599 ,  H01L2224/05099 ,  H01L2224/29099 ,  H01L2224/29599 ,  H01L2924/014 ,  H01L2924/00

    Abstract: Disclosed are a nanoparticle having a size of 1-20nm prepared by electrolyzing a tin or a tin alloy, and a method for preparing same. The nanoparticle surface-melts in a temperature range of 80-130?. A solder ball having the nanoparticle can be sintered at or below 160?, and can thus, first, save 22% of energy by resolving the energy consumption of 74 kW for the conventionally used reflow processing device to an energy consumption of 50 kW by enabling the heating temperature to be lowered from 240? to 160? during reflow process. Second, deformation of a PCB board can be minimized by enabling the temperature for the reflow process to be lowered, and application areas for implementation materials having a low unit cost can be created by enabling the use of low cost polymer materials such as PET having low glass transition temperature. And third, the uniformity of a solder paste on a pad can be enhance when using a nanoparticle having a size of 10 nm or smaller, and in the case of a nano-solder ink, the limitations of micro-patterning can be overcome due to the small size of the particle (Figure 4).

    Abstract translation: 公开了通过电解锡或锡合金制备的尺寸为1-20nm的纳米颗粒及其制备方法。 纳米颗粒表面在80-130℃的温度范围内熔融。 具有纳米颗粒的焊球可以在或低于160℃烧结，因此首先可以通过将常规使用的回流处理装置的74kW的能量消耗解决为50kW的能量消耗来节省22％的能量 加热温度从240？ 到160？ 在回流过程中。 第二，可以通过降低回流工艺的温度来降低PCB板的变形，并且可以通过使用低成本的聚合物材料（例如具有低的PET）来制造具有低单位成本的实施材料的应用领域 玻璃化转变温度。 第三，当使用尺寸为10nm或更小的纳米颗粒时，可以增强焊盘上的焊膏的均匀性，并且在纳米焊料墨水的情况下，可以克服微图案化的限制，因为 颗粒尺寸小（图4）。

    NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES
    5.
    发明申请
    NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES 审中-公开
    具有增强皮肤渗透性，细胞摄取和肿瘤递送特性的纳米颗粒

    公开(公告)号：WO2011090349A3

    公开(公告)日：2011-12-29

    申请号：PCT/KR2011000449

    申请日：2011-01-21

    Applicant: KWANGJU INST SCI & TECH ,  TAE GI YOONG ,  CHOI WON IL ,  KIM YOUNG HA ,  KIM JA-YOUNG ,  LEE JONG HYUN

    Inventor： TAE GI YOONG ,  CHOI WON IL ,  KIM YOUNG HA ,  KIM JA-YOUNG ,  LEE JONG HYUN

    IPC: A61K47/48 ,  A61K9/20 ,  A61K9/48 ,  A61K47/30 ,  A61K49/08 ,  A61P35/00

    CPC classification number: A61K9/0014 ,  A61K47/61

    Abstract: The present invention relates to a biopolymer-modified nanocarrier in which chitosan is bound to a water-soluble biocompatible polymer that has been crosslinked via a photo-crosslinkable functional group; wherein the chitosan-modified nanocarrier has a diameter which changes in accordance with changes in temperature, has enhanced skin permeability or cellular uptake and selective delivery to cancer tissue as compared with a bare nanocarrier to which chitosan has not been bound, and exhibits characteristics that are advantageous in photothermal therapy. The chitosan-modified nanocarrier of the present invention exhibits highly superior efficacy as a transdermal carrier, since the skin permeability is enhanced to a very suppressing level as compared with a bare nanocarrier that has no chitosan. The chitosan-modified nanocarrier of the present invention can be used to very great advantage in the imaging and photothermal therapy of tumour cells and cancer cells, since the cellular uptake by tumour cells and cancer cells is substantially improved.

    Abstract translation: 本发明涉及生物聚合物改性的纳米载体，其中壳聚糖与已经通过光交联官能团交联的水溶性生物相容性聚合物结合; 其中壳聚糖修饰的纳米载体具有根据温度变化而变化的直径，与未结合壳聚糖的裸纳米载体相比具有增强的皮肤渗透性或细胞摄取和选择性递送至癌组织，并且具有以下特征： 有利于光热治疗。 本发明的脱乙酰壳多糖修饰的纳米载体作为透皮载体具有高度优异的功效，因为与不含壳聚糖的裸纳米载体相比，皮肤渗透性提高到非常低的抑制水平。 本发明的壳聚糖修饰的纳米载体可以用于肿瘤细胞和癌细胞的成像和光热治疗中的非常大的优点，因为肿瘤细胞和癌细胞的细胞摄取被显着改善。

    AMPLIFIER SUPPORTING MULTI MODE AND AMPLIFYING METHOD THEREOF
    7.
    发明申请
    AMPLIFIER SUPPORTING MULTI MODE AND AMPLIFYING METHOD THEREOF 审中-公开
    放大器支持多模式及放大方法

    公开(公告)号：WO2012018233A3

    公开(公告)日：2012-05-10

    申请号：PCT/KR2011005721

    申请日：2011-08-04

    Applicant: SAMSUNG ELECTRONICS CO LTD ,  LEE JONG HYUN

    Inventor： LEE JONG HYUN

    IPC: H03F1/30 ,  H03F3/24

    CPC classification number: H04L5/14 ,  H03F1/0205 ,  H03F1/0261 ,  H03F1/30 ,  H03F3/189 ,  H03F3/19 ,  H03F3/24 ,  H03F2200/18 ,  H03F2200/294 ,  H03F2200/408 ,  H03F2200/451 ,  H03F2200/468 ,  H04W88/06

    Abstract: An amplifier and an amplifying method are provided. The amplifier includes: an amplifying unit amplifying and transferring a transmission target signal to a TDD switch; the TDD switch transferring a signal received from the amplifying unit to a filter unit when the amplifier operates in a TDD mode, and transferring a signal received from the filter unit to a duplex mode selection switch; the duplex mode selection switch transferring a signal received from the filter unit to a receiving side; and a controller controlling the duplex mode selection switch to transfer the signal received from the filter unit to the receiving side without passing through the TDD switch when the received duplex mode selection signal is a FDD mode selection signal.

    Abstract translation: 提供放大器和放大方法。 该放大器包括：放大单元，将发送目标信号放大并传送到TDD开关; TDD开关在放大器工作在TDD模式时将从放大单元接收到的信号传送到滤波单元，并且将从滤波单元接收的信号传送到双工模式选择开关; 双工模式选择开关将从滤波器单元接收的信号传送到接收侧; 以及控制器，当所接收的双工模式选择信号是FDD模式选择信号时，控制器控制双工模式选择开关将从滤波器单元接收到的信号传送到接收侧而不经过TDD开关。

    METHOD FOR SEPARATING AND IDENTIFYING CALGRANULIN A AS A DEMENTIA MARKER FROM BLOOD CELLS
    8.
    发明申请
    METHOD FOR SEPARATING AND IDENTIFYING CALGRANULIN A AS A DEMENTIA MARKER FROM BLOOD CELLS 审中-公开
    用于分离和鉴定作为来自血细胞的DEMENTIA标记的钙调素A的方法

    公开(公告)号：WO2012011731A2

    公开(公告)日：2012-01-26

    申请号：PCT/KR2011005328

    申请日：2011-07-20

    Applicant: LEE SONG-JAE ,  LEE JONG-MIN ,  LEE JONG-HYUN

    Inventor： LEE SONG-JAE ,  LEE JONG-MIN ,  LEE JONG-HYUN

    IPC: C07K1/16 ,  A61K39/395 ,  A61P25/28 ,  C07K1/26

    CPC classification number: C07K16/24 ,  C07K14/52 ,  C07K16/18

    Abstract: The present invention relates to a method for separating calgranulin A and ß-actin as dementia markers which can be utilized in the diagnosis and treatment of dementia, and to a composition for the treatment and identification of dementia (Alzheimer's disease, vascular dementia, alcoholic dementia), comprising an antibody that specifically binds to the calgranulin A and to â-actin. The separation method of the present invention comprises the following steps: separating blood cells containing leucocytes (neutrophils, monocytes, macrophages, granulocytes, etc.), erythrocytes, platelets, and the like from blood; performing DEAE-cellulose column chromatography on the blood cells; precipitating the blood cells using 30 to 80% of ammonium sulfate; performing ubiquitin-Sepharose affinity column chromatography on the blood cells; performing electrophoresis on the blood cells; and checking the proteins of the blood cells.

    Abstract translation: 本发明涉及一种分离钙粒蛋白A和β-肌动蛋白作为可用于诊断和治疗痴呆症的痴呆标记物，以及用于治疗和鉴定痴呆症的组合物（阿尔茨海默病，血管性痴呆，酒精性痴呆 ），其包含特异性结合钙调蛋白A和抗肌动蛋白的抗体。 本发明的分离方法包括以下步骤：从血液中分离含有白细胞（嗜中性粒细胞，单核细胞，巨噬细胞，粒细胞等），红细胞，血小板等的血细胞; 在血细胞上进行DEAE-纤维素柱层析; 使用30〜80％的硫酸铵沉淀血细胞; 在血细胞上进行泛素 - 琼脂糖亲和柱层析; 在血细胞上进行电泳; 并检查血细胞的蛋白质。

    MICRO MATRIX RELAY SWITCH
    10.
    发明申请
    MICRO MATRIX RELAY SWITCH 审中-公开

    公开(公告)号：WO2009102129A3

    公开(公告)日：2009-08-20

    申请号：PCT/KR2009/000603

    申请日：2009-02-10

    Applicant: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Jong Hyun ,  HWANG, Il Han

    Inventor： LEE, Jong Hyun ,  HWANG, Il Han

    IPC: H01H9/12

    Abstract: A matrix relay switch structure that is suitable for micro miniaturization is provided. A matrix switch for electrical signal connection between at least one signal input terminal and at least one signal output terminal is composed of electrical switches, each electrical switch including a signal connection unit opening and closing an electrical connection between a signal input terminal and a signal output terminal corresponding to each other, a first movable driver connected to the signal connection unit and driving the signal connection unit forward or backward, a forward/backward driving unit driving the first movable driver forward or backward and changing an electrical connection state made by the signal connection unit between the signal input terminal and the signal output terminal, and a bistable spring unit connected to the first movable driver and maintaining the electrical connection state while a stability state changes due to the first movable driver. Accordingly, a micro matrix relay switch that is micro miniature yet has excellent stability and expandability can be constituted.

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