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    REACTION ASSEMBLY AND FLOW SPLITTER
    1.
    发明申请
    REACTION ASSEMBLY AND FLOW SPLITTER 审中-公开
    反应组件和流动分离器

    公开(公告)号：WO2009145614A2

    公开(公告)日：2009-12-03

    申请号：PCT/NL2009/000122

    申请日：2009-05-26

    Applicant: Avantium Holding B.V. ,  MOONEN, Roelandus Hendrikus Wilhelmus ,  BODENSTAFF, Emilio René ,  SMIT, Martin

    Inventor： MOONEN, Roelandus Hendrikus Wilhelmus ,  BODENSTAFF, Emilio René ,  SMIT, Martin

    IPC: G05D7/06

    CPC classification number: G05D7/0635 ,  B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00306 ,  B01J2219/00418 ,  B01J2219/00587 ,  G05D11/132 ,  Y10T137/2514

    Abstract: The invention pertains to reaction systems in which at least one capillary unit is applied. The capillary unit comprises: - a unit inlet for receiving a fluid flow, - a unit outlet for releasing said fluid flow, - a capillary, which capillary is arranged between the unit inlet and the unit outlet such that said fluid flow passes through the capillary, - a heater and/or a cooler for adjusting the temperature of the capillary and therewith influencing the flow rate of the fluid flow passing through said capillary, - a housing for accommodating at least the capillary and heater and/or cooler of said capillary unit, which housing provides thermal insulation of the capillary, - a flow sensor for measuring the flow rate of the fluid flow through the capillary unit, which flow sensor can be arranged either inside or outside the housing, A capillary unit is combined with or further has a flow adjustment unit for adjusting the flow rates of the secondary fluid flows, which flow adjustment unit comprises a temperature control device for individually controlling the heater and/or cooler of each capillary unit in response to the flow rate that is measured by the flow sensor of that capillary unit.

    Abstract translation: 本发明涉及应用至少一个毛细管单元的反应系统。 毛细管单元包括： - 用于接收流体流的单元入口， - 用于释放所述流体流的单元出口， - 毛细管，毛细管布置在单元入口和单元出口之间，使得所述流体流动通过毛细管 ， - 加热器和/或冷却器，用于调节毛细管的温度并因此影响通过所述毛细管的流体流的流速; - 用于至少容纳所述毛细管单元的毛细管和加热器和/或冷却器的壳体 ，该壳体提供毛细管的热绝缘， - 流量传感器，用于测量通过毛细管单元的流体流量的流量，该流量传感器可以布置在壳体的内部或外部。毛细管单元结合或进一步具有 用于调节二次流体流量的流量调节单元，该流量调节单元包括用于单独控制加热器和/或冷却器的温度控制装置 每个毛细管单元响应于由该毛细管单元的流量传感器测量的流量。

    REACTION ASSEMBLY AND FLOW SPLITTER
    2.
    发明申请
    REACTION ASSEMBLY AND FLOW SPLITTER 审中-公开
    反应组件和流动分离器

    公开(公告)号：WO2009145614A3

    公开(公告)日：2011-01-06

    申请号：PCT/NL2009000122

    申请日：2009-05-26

    Applicant: AVANTIUM HOLDING B V ,  MOONEN ROELANDUS HENDRIKUS WILHELMUS ,  BODENSTAFF EMILIO RENE ,  SMIT MARTIN

    Inventor： MOONEN ROELANDUS HENDRIKUS WILHELMUS ,  BODENSTAFF EMILIO RENE ,  SMIT MARTIN

    IPC: G05D7/06 ,  G05D11/13

    CPC classification number: G05D7/0635 ,  G05D11/132 ,  Y10T137/2514

    Abstract: The invention pertains to reaction systems in which at least one capillary unit is applied. The capillary unit comprises: - a unit inlet for receiving a fluid flow, - a unit outlet for releasing said fluid flow, - a capillary, which capillary is arranged between the unit inlet and the unit outlet such that said fluid flow passes through the capillary, - a heater and/or a cooler for adjusting the temperature of the capillary and therewith influencing the flow rate of the fluid flow passing through said capillary, - a housing for accommodating at least the capillary and heater and/or cooler of said capillary unit, which housing provides thermal insulation of the capillary, - a flow sensor for measuring the flow rate of the fluid flow through the capillary unit, which flow sensor can be arranged either inside or outside the housing, A capillary unit is combined with or further has a flow adjustment unit for adjusting the flow rates of the secondary fluid flows, which flow adjustment unit comprises a temperature control device for individually controlling the heater and/or cooler of each capillary unit in response to the flow rate that is measured by the flow sensor of that capillary unit.

    Abstract translation: 本发明涉及应用至少一个毛细管单元的反应系统。 毛细管单元包括： - 用于接收流体流的单元入口， - 用于释放所述流体流的单元出口， - 毛细管，毛细管布置在单元入口和单元出口之间，使得所述流体流动通过毛细管 ， - 加热器和/或冷却器，用于调节毛细管的温度并因此影响通过所述毛细管的流体流的流速; - 用于至少容纳所述毛细管单元的毛细管和加热器和/或冷却器的壳体 ，该壳体提供毛细管的热绝缘， - 流量传感器，用于测量通过毛细管单元的流体流量的流量，该流量传感器可以布置在壳体的内部或外部。毛细管单元结合或进一步具有 用于调节二次流体流量的流量调节单元，该流量调节单元包括用于单独控制加热器和/或冷却器的温度控制装置 每个毛细管单元响应于由该毛细管单元的流量传感器测量的流量。

    CORROSION SIMULATOR AND THE CORRESPONDENCE METHOD
    3.
    发明申请
    CORROSION SIMULATOR AND THE CORRESPONDENCE METHOD 审中-公开
    腐蚀模拟器和相关方法

    公开(公告)号：WO2008115050A1

    公开(公告)日：2008-09-25

    申请号：PCT/NL2008/000084

    申请日：2008-03-19

    Applicant: AVANTIUM INTERNATIONAL B.V. ,  GRUTER, Gerardus, Johannes, Maria ,  MOONEN, Roelandus, Hendrikus, Wilhelmus ,  DE JONG, Jan, Peter ,  KNOWLES, David, Michael

    Inventor： GRUTER, Gerardus, Johannes, Maria ,  MOONEN, Roelandus, Hendrikus, Wilhelmus ,  DE JONG, Jan, Peter ,  KNOWLES, David, Michael

    IPC: G01N17/00

    CPC classification number: G01N17/002

    Abstract: The invention relates to a laboratory degradation test system for testing degradation of a test specimen in a test fluid flow, the test system comprising: - a reactor assembly, which reactor assembly comprises: - a reactor vessel, the reactor vessel having a reaction space, an inlet and an outlet and a specimen holder for retaining a test specimen inside the reactor vessel, - a heater for heating the reactor vessel, - a fluid circulation system generating a test fluid flow over the test specimen, which fluid circulation system comprises: - a circulation line which extends between the outlet of the reactor vessel and the inlet of the reactor vessel, which circulation line is arranged outside the reactor vessel, - a pump for providing fluid circulation through the circulation line and the reactor vessel, which pump is arranged in the circulation line. The laboratory test system according to the invention is characterised in that the volume available to the test fluid inside the reaction space after insertion of the degradation test specimen is less than or equal to 10 ml.

    Abstract translation: 本发明涉及一种用于测试测试流体流中试样退化的实验室降解测试系统，该测试系统包括：反应器组件，该反应器组件包括： - 反应器容器，反应器容器具有反应空间， 入口和出口以及用于将测试样品保持在反应器容器内的样品架， - 用于加热反应器容器的加热器， - 在测试样品上产​​生测试流体流体的流体循环系统，该流体循环系统包括： 在反应器容器的出口和反应器容器的入口之间延伸的循环管线，该循环管线布置在反应器容器的外部， - 用于通过循环管线和反应器容器提供流体循环的泵，该泵布置 在流通线。 根据本发明的实验室测试系统的特征在于，在插入降解试样后，反应空间内的测试流体可用的体积小于或等于10ml。

    FLOW CONTROLLER ASSEMBLY FOR MICROFLUIDIC APPLICATIONS AND SYSTEM FOR PERFORMING A PLURALITY OF EXPERIMENTS IN PARALLEL
    6.
    发明申请
    FLOW CONTROLLER ASSEMBLY FOR MICROFLUIDIC APPLICATIONS AND SYSTEM FOR PERFORMING A PLURALITY OF EXPERIMENTS IN PARALLEL 审中-公开
    用于微流控应用的流量控制器组件和并行执行多项实验的系统

    公开(公告)号：WO2010107302A3

    公开(公告)日：2011-02-24

    申请号：PCT/NL2010000044

    申请日：2010-03-16

    Applicant: AVANTIUM HOLDING B V ,  BODENSTAFF EMILIO RENE ,  MOONEN ROELANDUS HENDRIKUS WILHELMUS

    Inventor： BODENSTAFF EMILIO RENE ,  MOONEN ROELANDUS HENDRIKUS WILHELMUS

    IPC: G05D7/06 ,  F15C1/04

    CPC classification number: G05D7/0694 ,  F15C1/04 ,  F16K99/0001 ,  F16K99/0021 ,  F16K99/0032 ,  F16K99/0036 ,  F16K2099/0084 ,  Y10T137/6416

    Abstract: The invention pertains to a flow controller assembly for microfluidic applications, which flow controller assembly comprises at least one microfluidic flow controller, which microfluidic flow controller comprises: - a microfluidic chip, which microfluidic chip comprises a channel for accommodating a fluid flow, which channel runs through said microfluidic chip and has a channel inlet that is connectable to a fluid source and a channel outlet that is connectable to a further fluid conduit, - a thermal energy transmitter, which thermal energy transmitter is adapted for heating and/or cooling at least a part of the channel by producing a thermal output, thereby influencing the flow rate of fluid that is present in said channel, - a flow sensor for measuring the flow rate of a fluid running through the flow controller, said flow sensor being adapted to produce flow rate measurement data, - a data control unit, which is connected to the flow sensor by a first data connection which first data connection allows the data control unit to receive flow rate measurement data from the flow sensor, which data control unit is connected to the thermal energy transmitter by a second data connection, which second data connection allows the data control unit to influence the thermal output of the thermal energy transmitter, which data control unit comprises a data processing unit that is adapted to determine the difference between the measured flow rate and a preset desired flow rate and to regulate the thermal output of the thermal energy transmitter in order to obtain or maintain the desired flow rate.

    Abstract translation: 本发明涉及用于微流体应用的流量控制器组件，该流量控制器组件包括至少一个微流体流量控制器，该微流体流量控制器包括： - 微流体芯片，该微流体芯片包括用于容纳流体流动的通道，该通道运行 通过所述微流体芯片并且具有可连接到流体源的通道入口和可连接到另外的流体导管的通道出口， - 热能发射器，所述热能发射器适于加热和/或冷却至少一个 通过产生热输出的一部分通道，从而影响存在于所述通道中的流体的流速;流量传感器，用于测量流过流量控制器的流体的流量，所述流量传感器适于产生流量 速率测量数据， - 数据控制单元，其通过第一数据连接与第一数据连接到流量传感器 连接允许数据控制单元从流量传感器接收流量测量数据，该数据控制单元通过第二数据连接连接到热能发射器，该第二数据连接允许数据控制单元影响热输出 所述热能发射器，所述数据控制单元包括数据处理单元，所述数据处理单元适于确定所测量的流量与预设的所需流速之间的差异，并且调节所述热能发射器的热输出以获得或维持 所需流速。

    FLOW CONTROLLER ASSEMBLY FOR MICROFLUIDIC APPLICATIONS AND SYSTEM FOR PERFORMING A PLURALITY OF EXPERIMENTS IN PARALLEL
    7.
    发明申请
    FLOW CONTROLLER ASSEMBLY FOR MICROFLUIDIC APPLICATIONS AND SYSTEM FOR PERFORMING A PLURALITY OF EXPERIMENTS IN PARALLEL 审中-公开
    用于微流控应用的流量控制器组件和并行执行多项实验的系统

    公开(公告)号：WO2010107302A2

    公开(公告)日：2010-09-23

    申请号：PCT/NL2010/000044

    申请日：2010-03-16

    Applicant: AVANTIUM HOLDING B.V. ,  BODENSTAFF, Emilio, René ,  MOONEN, Roelandus, Hendrikus, Wilhelmus

    Inventor： BODENSTAFF, Emilio, René ,  MOONEN, Roelandus, Hendrikus, Wilhelmus

    IPC: G05D7/06 ,  F15C1/04

    CPC classification number: G05D7/0694 ,  F15C1/04 ,  F16K99/0001 ,  F16K99/0021 ,  F16K99/0032 ,  F16K99/0036 ,  F16K2099/0084 ,  Y10T137/6416

    Abstract: The invention pertains to a flow controller assembly for microfluidic applications, which flow controller assembly comprises at least one microfluidic flow controller, which microfluidic flow controller comprises: - a microfluidic chip, which microfluidic chip comprises a channel for accommodating a fluid flow, which channel runs through said microfluidic chip and has a channel inlet that is connectable to a fluid source and a channel outlet that is connectable to a further fluid conduit, - a thermal energy transmitter, which thermal energy transmitter is adapted for heating and/or cooling at least a part of the channel by producing a thermal output, thereby influencing the flow rate of fluid that is present in said channel, - a flow sensor for measuring the flow rate of a fluid running through the flow controller, said flow sensor being adapted to produce flow rate measurement data, - a data control unit, which is connected to the flow sensor by a first data connection which first data connection allows the data control unit to receive flow rate measurement data from the flow sensor, which data control unit is connected to the thermal energy transmitter by a second data connection, which second data connection allows the data control unit to influence the thermal output of the thermal energy transmitter, which data control unit comprises a data processing unit that is adapted to determine the difference between the measured flow rate and a preset desired flow rate and to regulate the thermal output of the thermal energy transmitter in order to obtain or maintain the desired flow rate.

    Abstract translation: 本发明涉及用于微流体应用的流量控制器组件，该流量控制器组件包括至少一个微流体流量控制器，该微流体流量控制器包括： - 微流体芯片，该微流体芯片包括用于容纳流体流动的通道，该通道运行 通过所述微流体芯片并且具有可连接到流体源的通道入口和可连接到另外的流体导管的通道出口， - 热能发射器，所述热能发射器适于加热和/或冷却至少一个 通过产生热输出的一部分通道，从而影响存在于所述通道中的流体的流速;流量传感器，用于测量流过流量控制器的流体的流量，所述流量传感器适于产生流量 速率测量数据， - 数据控制单元，其通过第一数据连接与第一数据连接到流量传感器 连接允许数据控制单元从流量传感器接收流量测量数据，该数据控制单元通过第二数据连接连接到热能发射器，该第二数据连接允许数据控制单元影响热输出 所述热能发射器，所述数据控制单元包括数据处理单元，所述数据处理单元适于确定所测量的流量与预设的所需流速之间的差异，并且调节所述热能发射器的热输出以获得或维持 所需流速。

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