公开(公告)号：WO2004092121A2

公开(公告)日：2004-10-28

申请号：PCT/US2004/010639

申请日：2004-04-07

Applicant: NPS PHARMACEUTICALS, INC. ,  SHCHERBAKOVA, Irina ,  BALANDRIN, Manuel ,  HUANG, Guangfei ,  GEOFFROY, Otto ,  FOX, John ,  NAIR, Satheesh, K.

Inventor： SHCHERBAKOVA, Irina ,  BALANDRIN, Manuel ,  HUANG, Guangfei ,  GEOFFROY, Otto ,  FOX, John ,  NAIR, Satheesh, K.

IPC: C07D

CPC classification number: C07D239/36 ,  C07D239/70 ,  C07D239/91 ,  C07D401/04

Abstract: Pyrimidinone compounds are disclosed. Methods of preparing the pyrimidinone compounds are also disclosed.

Abstract translation: 公开了嘧啶酮化合物。 还公开了制备嘧啶酮化合物的方法。

公开(公告)号：WO2010054009A1

公开(公告)日：2010-05-14

申请号：PCT/US2009/063302

申请日：2009-11-04

Applicant: NOVABAY PHARMACEUTICALS, INC. ,  JAIN, Rakesh, K. ,  LOW, Eddy ,  FRANCAVILLA, Charles ,  SHIAU, Timothy P. ,  KIM, Bum ,  NAIR, Satheesh, K.

Inventor： JAIN, Rakesh, K. ,  LOW, Eddy ,  FRANCAVILLA, Charles ,  SHIAU, Timothy P. ,  KIM, Bum ,  NAIR, Satheesh, K.

IPC: A01N43/76 ,  A61K31/42 ,  A61K31/415

CPC classification number: A01N43/76 ,  A01N35/02 ,  A01N43/90 ,  A01N59/00 ,  A61K31/415 ,  A61K31/42 ,  C07D233/80 ,  C07D233/82 ,  C07D263/20 ,  C07D263/26 ,  C07D471/10 ,  C07D498/10

Abstract: The present application relates to N -chlorinated oxazolidinone, hydantoin and imidazolidinone compounds of Formula (I): or pharmaceutically acceptable salts thereof, and associated compositions and methods of use as antimicrobial agents.

Abstract translation: 本申请涉及式（I）的N-氯化恶唑烷酮，乙内酰脲和咪唑烷酮化合物或其药学上可接受的盐，以及作为抗微生物剂的相关组合物和用途的方法。

公开(公告)号：WO2008083347A1

公开(公告)日：2008-07-10

申请号：PCT/US2007/089143

申请日：2007-12-28

Applicant: NOVABAY PHARMACEUTICALS, INC. ,  NAJAFI, Ramin ,  JAIN, Rakesh K. ,  SHIAU, Timothy P. ,  LOW, Eddy ,  NAIR, Satheesh K.

Inventor： NAJAFI, Ramin ,  JAIN, Rakesh K. ,  SHIAU, Timothy P. ,  LOW, Eddy ,  NAIR, Satheesh K.

IPC: A61K31/69 ,  A61K33/14

CPC classification number: A61K31/69 ,  A61K33/00 ,  C07C309/10 ,  C07C309/12 ,  C07C309/17 ,  C07C309/19 ,  C07C309/24 ,  C07C309/26 ,  C07C311/32 ,  C07C311/46 ,  C07C317/28 ,  C07C2601/14 ,  C07C2601/18 ,  C07D211/52 ,  C07D307/22 ,  A61K2300/00

Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.

Abstract translation: 本发明涉及活性杀菌，抗细菌，抗感染，抗微生物，杀芽孢，消毒剂，抗真菌和抗病毒化合物和组合物以及这些组合物在治疗中的新用途。 本说明书还描述了新化合物和组合物的使用方法。 本说明书还描述了制备这些化合物的方法。

公开(公告)号：WO2006066070A2

公开(公告)日：2006-06-22

申请号：PCT/US2005/045565

申请日：2005-12-16

Applicant: NPS PHARMACEUTICALS, INC. ,  SHCHERBAKOVA, Irina ,  WERMUTH, Camille, G. ,  JEANNOT, Frederic ,  CIAPETTI, Paola ,  ROQUES, Virginie ,  JUNG, Laetitia, M. ,  BALANDRIN, Manuel, F. ,  NAIR, Satheesh, K. ,  SWIERCZEK, Krzysztof ,  MCCAFFREY, Jennifer ,  HEATON, William, L. ,  BREINHOLT, Jeff, A. ,  CONKLIN, Rebecca, L.

Inventor： SHCHERBAKOVA, Irina ,  WERMUTH, Camille, G. ,  JEANNOT, Frederic ,  CIAPETTI, Paola ,  ROQUES, Virginie ,  JUNG, Laetitia, M. ,  BALANDRIN, Manuel, F. ,  NAIR, Satheesh, K. ,  SWIERCZEK, Krzysztof ,  MCCAFFREY, Jennifer ,  HEATON, William, L. ,  BREINHOLT, Jeff, A. ,  CONKLIN, Rebecca, L.

IPC: A61K31/513

CPC classification number: C07D239/91 ,  C07D239/36

Abstract: Various calcilytic compounds and prodrugs of calcilytic compounds are disclosed. Calcilytic compounds are compounds capable of inhibiting calcium receptor activity. Methods for preparing these compounds, oral bioavailability of these compounds, pharmaceutical compositions containing these compounds and their use as calcium receptor antagonists are also disclosed.

Abstract translation: 公开了各种钙化合物和钙化合物的前体药物。 钙化合物是能够抑制钙受体活性的化合物。 还公开了制备这些化合物的方法，这些化合物的口服生物利用度，含有这些化合物的药物组合物及其作为钙受体拮抗剂的用途。

公开(公告)号：WO2006066070A3

公开(公告)日：2006-09-21

申请号：PCT/US2005045565

申请日：2005-12-16

Applicant: NPS PHARMA INC ,  SHCHERBAKOVA IRINA ,  WERMUTH CAMILLE G ,  JEANNOT FREDERIC ,  CIAPETTI PAOLA ,  ROQUES VIRGINIE ,  JUNG LAETITIA M ,  BALANDRIN MANUEL F ,  NAIR SATHEESH K ,  SWIERCZEK KRZYSZTOF ,  MCCAFFREY JENNIFER ,  HEATON WILLIAM L ,  BREINHOLT JEFF A ,  CONKLIN REBECCA L

Inventor： SHCHERBAKOVA IRINA ,  WERMUTH CAMILLE G ,  JEANNOT FREDERIC ,  CIAPETTI PAOLA ,  ROQUES VIRGINIE ,  JUNG LAETITIA M ,  BALANDRIN MANUEL F ,  NAIR SATHEESH K ,  SWIERCZEK KRZYSZTOF ,  MCCAFFREY JENNIFER ,  HEATON WILLIAM L ,  BREINHOLT JEFF A ,  CONKLIN REBECCA L

IPC: C07D239/36 ,  A61K31/513 ,  C07C229/12

CPC classification number: C07D239/91 ,  C07D239/36

Abstract: Various calcilytic compounds and prodrugs of calcilytic compounds are disclosed. Calcilytic compounds are compounds capable of inhibiting calcium receptor activity. Methods for preparing these compounds, oral bioavailability of these compounds, pharmaceutical compositions containing these compounds and their use as calcium receptor antagonists are also disclosed.

Abstract translation: 公开了各种钙溶解化合物和钙溶解化合物的前体药物。 钙溶解化合物是能够抑制钙受体活性的化合物。 还公开了制备这些化合物的方法，这些化合物的口服生物利用度，含有这些化合物的药物组合物以及它们作为钙受体拮抗剂的用途。

公开(公告)号：WO2010054269A1

公开(公告)日：2010-05-14

申请号：PCT/US2009/063652

申请日：2009-11-06

Applicant: NOVABAY PHARMACEUTICALS, INC. ,  JAIN, Rakesh, K. ,  LOW, Eddy ,  FRANCAVILLA, Charles ,  SHIAU, Timothy, P. ,  NAIR, Satheesh, K.

Inventor： JAIN, Rakesh, K. ,  LOW, Eddy ,  FRANCAVILLA, Charles ,  SHIAU, Timothy, P. ,  NAIR, Satheesh, K.

IPC: A61K8/00

CPC classification number: C07C229/12 ,  A61K31/14 ,  C07C229/34 ,  C07C271/54

Abstract: The present application relates to TV-chlorinated cationic compounds of Formula I or a salt thereof, and associated compositions and methods of use as antimicrobial agents.

Abstract translation: 本申请涉及式I的电视氯化阳离子化合物或其盐，以及作为抗微生物剂的相关组合物和用途。

公开(公告)号：WO2004092121A3

公开(公告)日：2005-04-14

申请号：PCT/US2004010639

申请日：2004-04-07

Applicant: NPS PHARMA INC ,  SHCHERBAKOVA IRINA ,  BALANDRIN MANUEL ,  HUANG GUANGFEI ,  GEOFFROY OTTO ,  FOX JOHN ,  NAIR SATHEESH K

Inventor： SHCHERBAKOVA IRINA ,  BALANDRIN MANUEL ,  HUANG GUANGFEI ,  GEOFFROY OTTO ,  FOX JOHN ,  NAIR SATHEESH K

IPC: A61K31/505 ,  A61K31/517 ,  C07D20060101 ,  C07D239/36 ,  C07D239/80 ,  C07D239/91

CPC classification number: C07D239/36 ,  C07D239/70 ,  C07D239/91 ,  C07D401/04

Abstract: Pyrimidinone compounds are disclosed. Methods of preparing the pyrimidinone compounds are also disclosed.

Abstract translation: 公开了嘧啶酮化合物。 还公开了制备嘧啶酮化合物的方法。