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    FLOW RATE CONTROL
    1.
    发明申请
    FLOW RATE CONTROL 审中-公开

    公开(公告)号：WO2004112960A3

    公开(公告)日：2004-12-29

    申请号：PCT/US2004/015838

    申请日：2004-05-19

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    Inventor： NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    IPC: G01N1/00

    Abstract: A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. Fluid supplies (20A, 20B) supply working fluids at flow rates measured by flow meters (24A, 24B). Rotary valve (12) has six external ports (12A-12F). The outputs of the working fluids are combined and delivered to port (12A). Port (12B) is connected via loading conduit (181) to µLC column (18), the output of which flows to detector (26). A controller (22) controls the operation of valve (12) and supplies (20A, 20B), using input from the flow meters.

    FLOW RATE CONTROL
    2.
    发明申请
    FLOW RATE CONTROL 审中-公开
    流量控制

    公开(公告)号：WO2004112960A2

    公开(公告)日：2004-12-29

    申请号：PCT/US2004/015838

    申请日：2004-05-19

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    Inventor： NEYER, David, W. ,  RAKESTRAW, David, J. ,  REHM, Jason, E.

    IPC: B01L

    CPC classification number: G01N30/16 ,  G01N2030/324 ,  Y10T436/2575

    Abstract: A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably provided by variable rate working fluid supplies which drive the sample from the preparation site and through the device.

    Abstract translation: 在制备部位制备液体样品，然后加工，例如 在HPLC柱中。 制备样品并以基本上小于通过装置的流速的流速将其输送到装置。 不同的流速优选由可变速率的工作流体供应提供，驱动样品从制备部位并通过该装置。

    ELECTROOSMOTIC FLOW SYSTEMS
    3.
    发明申请
    ELECTROOSMOTIC FLOW SYSTEMS 审中-公开
    电动流量系统

    公开(公告)号：WO2003093674A2

    公开(公告)日：2003-11-13

    申请号：PCT/US2003/013315

    申请日：2003-04-30

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  PAUL, Phillip, H. ,  NEYER, David, W.

    Inventor： PAUL, Phillip, H. ,  NEYER, David, W.

    IPC: F04B19/00

    CPC classification number: G01N27/447 ,  B01L3/5027 ,  F04B17/00 ,  F04B19/006 ,  G01N27/401 ,  G01N27/44704

    Abstract: Electroosmotic flow systems containing two or more electroosmotic flow elements which meet at a junction, at least one of the electroosmotic flow elements having a substantial charge ratio. The electroosmotic flow elements have matching flux ratios. The electroosmotic flow elements may contain porous materials whose terminal portions are shaped to increase the surface area exposed to the fluid at the junction. Examples of such terminals are illustrated in the figure.

    Abstract translation: 含有两个或更多个渗透流动元件的电渗流系统，其在接合处相遇，至少一个电渗流体元件具有相当大的电荷比。 电渗流量元件具有匹配的通量比。 电渗流元件可以包含多孔材料，其端部被成形以增加在接合部处暴露于流体的表面积。 这种端子的示例在附图中示出。

    ELECTROKINETIC DELIVERY SYSTEMS, DEVICES AND METHODS
    4.
    发明申请
    ELECTROKINETIC DELIVERY SYSTEMS, DEVICES AND METHODS 审中-公开
    电动输送系统，装置和方法

    公开(公告)号：WO2005113419A3

    公开(公告)日：2007-12-27

    申请号：PCT/US2005013728

    申请日：2005-04-21

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  ANEX DEON S ,  PAUL PHILLIP H ,  NEYER DAVID W ,  HLAVKA EDWIN K

    Inventor： ANEX DEON S ,  PAUL PHILLIP H ,  NEYER DAVID W ,  HLAVKA EDWIN K

    IPC: F04F99/00 ,  A61M1/00 ,  A61M5/142 ,  A61M5/145 ,  A61M5/148 ,  A61M5/172 ,  A61M31/00 ,  A61N1/30 ,  B67D99/00 ,  C25B9/00 ,  F04B19/00 ,  F04B43/04

    CPC classification number: A61M5/1483 ,  A61M5/14248 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2005/14513 ,  A61M2205/52 ,  A61M2230/201 ,  F04B19/006 ,  F04B43/043

    Abstract: Devices, systems and methods according to the present invention utilize electrokinetic pumps capable of generating high and low pressures flow for various medical applications, including drug delivery and analyte sampling. The EK pumps and systems are configured and constructed to be low cost, compact and precise. In one embodiment, the EK pump comprises a first fluid reservoir 102 and a second fluid reservoir 104. First fluid reservoir 102 is coupled to second fluid reservoir 104 by through- vias 106, 110 and porous dielectric material 108. Through-vias 106 and 110, along with porous dielectric material 108 proivde a fluidic path between first reservoir 102 and second reservoir 104. Each fluid rservoir further comprises a fluid port 118, which can be an inlet or outlet, and capacitive electrode 120a and 120b.

    Abstract translation: 根据本发明的装置，系统和方法利用能够产生用于各种医疗应用的高低压流动的电动泵，包括药物递送和分析物取样。 EK泵和系统的配置和构造是低成本，紧凑和精确的。 在一个实施例中，EK泵包括第一流体储存器102和第二流体储存器104.第一流体储存器102通过通孔106,110和多孔介电材料108连接到第二流体储存器104.通孔106和110 与多孔介电材料108一起产生第一储存器102和第二储存器104之间的流体路径。每个流体储存器还包括可以是入口或出口的流体端口118和电容电极120a和120b。

    BRIDGES FOR ELECTROOSMOTIC FLOW SYSTEMS
    5.
    发明申请
    BRIDGES FOR ELECTROOSMOTIC FLOW SYSTEMS 审中-公开
    电动流量系统桥

    公开(公告)号：WO2005011081A3

    公开(公告)日：2006-11-09

    申请号：PCT/US2004023623

    申请日：2004-07-21

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  PAUL PHILLIP H ,  NEYER DAVID W

    Inventor： PAUL PHILLIP H ,  NEYER DAVID W

    IPC: G01N27/453 ,  F04B17/00 ,  F04B19/00 ,  G01N27/447 ,  H02K20060101

    CPC classification number: F04B19/006 ,  F04B17/00

    Abstract: In accordance with the present invention, stable electroosmotic flow systems and methods for designing the same are disclosed. The invention provides electroosmotic flow systems comprising electroosmotic flow elements, including bridge elements, that have matching flux ratios, i.e., when two or more elements of an electroosmotic flow system are in fluidic and electrical communication at a junction, the flux ratio for each of the elements is selected so that the difference in flux ratios system adjacent two elements is less than a target value. The invention also provides methods for designing such systems.

    Abstract translation: 根据本发明，公开了稳定的电渗流系统及其设计方法。 本发明提供了电渗流系统，其包括具有匹配通量比的电渗流动元件（包括桥元件），即当电渗流系统的两个或多个元件在连接处处于流体和电连通时，每个的通量比 选择元件，使得相邻两个元件的通量比的差值小于目标值。 本发明还提供了用于设计这种系统的方法。

    ELECTROKINETIC DEVICES
    7.
    发明申请
    ELECTROKINETIC DEVICES 审中-公开
    电动装置

    公开(公告)号：WO2004036041A3

    公开(公告)日：2004-08-05

    申请号：PCT/US0332895

    申请日：2003-10-17

    Applicant: EKSIGENT TECHNOLOGIES LLC ,  ANEX DEON S ,  PAUL PHILLIP H ,  NEYER DAVID W

    Inventor： ANEX DEON S ,  PAUL PHILLIP H ,  NEYER DAVID W

    IPC: F04B17/00 ,  F04B19/00 ,  F04B43/04

    CPC classification number: F04B19/00 ,  F04B17/00 ,  F04B19/006 ,  F04B43/043

    Abstract: Electrokinetic devices, including electrokinetic pumps, include a conduit and first and second electrodes adjacent to respective ends of the conduit. The electrodes together constitute a capacitive electrode pair. The electrodes can be composed of double layer capacitive materials, for example carbon-based materials, or pseudocapacitive materials. The devices can operate without producing chemical change in the electrolyte solution.

    Abstract translation: 包括电动泵的电动装置包括导管以及与导管的相应端部相邻的第一和第二电极。 电极一起构成电容电极对。 电极可以由双层电容材料组成，例如碳基材料或伪电容材料。 该装置可以在电解质溶液中不产生化学变化的情况下操作。

    ELECTROKINETIC DEVICES
    8.
    发明申请
    ELECTROKINETIC DEVICES 审中-公开
    电动装置

    公开(公告)号：WO2004036041A2

    公开(公告)日：2004-04-29

    申请号：PCT/US2003/032895

    申请日：2003-10-17

    Applicant: EKSIGENT TECHNOLOGIES, LLC ,  ANEX, Deon, S. ,  PAUL, Phillip, H. ,  NEYER, David, W.

    Inventor： ANEX, Deon, S. ,  PAUL, Phillip, H. ,  NEYER, David, W.

    IPC: F04B19/00

    CPC classification number: F04B19/00 ,  F04B17/00 ,  F04B19/006 ,  F04B43/043

    Abstract: Electrokinetic devices, including electrokinetic pumps, include a conduit and first and second electrodes adjacent to respective ends of the conduit. The electrodes together constitute a capacitive electrode pair. The electrodes can be composed of double layer capacitive materials, for example carbon-based materials, or pseudocapacitive materials. The devices can operate without producing chemical change in the electrolyte solution.

    Abstract translation: 包括电动泵在内的电动装置包括导管以及与导管的相应末端相邻的第一和第二电极。 电极一起构成电容电极对。 电极可以由双层电容材料组成，例如碳基材料或假电容材料。 器件可以在电解液中不会产生化学变化的情况下工作。

    FLOW DEVICE
    9.
    发明申请
    FLOW DEVICE 审中-公开

    公开(公告)号：WO2004007080A3

    公开(公告)日：2004-01-22

    申请号：PCT/US2003/022306

    申请日：2003-07-16

    Applicant: EKSIGENT TECHNOLOGIES, LLC ,  PAUL, Phillip, H. ,  NEYER, David, W. ,  REHM, Jason, E.

    Inventor： PAUL, Phillip, H. ,  NEYER, David, W. ,  REHM, Jason, E.

    IPC: B01L3/00

    Abstract: Liquid flow devices, particularly microfluidic devices, containing solid porous materials. Flow in the devices can be pressure-driven flow and/or electroosmotic flow. The porous materials are preferably pre-shaped, for example divided from a sheet of porous material, so that they can be assembled with liquid-impermeable barrier materials around them. The devices can for example be prepared by lamination. A wide variety of devices, including mixing devices, is disclosed. A mixing device is illustrated in Figure 23.

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