中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

9 records (took 0.013 seconds)

    NUCLEOTIDE INCORPORATING ENZYMES
    1.
    发明申请
    NUCLEOTIDE INCORPORATING ENZYMES 审中-公开
    核苷酸合成酶（NUCLEOTIDE INCORPORATING ENZYMES）

    公开(公告)号：WO0210358A3

    公开(公告)日：2003-08-21

    申请号：PCT/US0124181

    申请日：2001-07-31

    Applicant: MAXYGEN INC ,  RAILLARD SUN AI ,  WELCH MARK ,  NESS JON

    Inventor： RAILLARD SUN AI ,  WELCH MARK ,  NESS JON

    IPC: C12N9/12 ,  C12N15/10 ,  C12P19/34 ,  C12Q1/68 ,  C12N9/00

    CPC classification number: C12N9/1252 ,  C12N15/1055 ,  C12P19/34 ,  C12Q1/6888

    Abstract: Nucleotide incorporating enzyme variants having improved properties including the ability to utilize non-natural or rare nucleotide analogues in the synthesis of polynucleotides are provided. Methods for producing such nucleotide incorporating enzyme variants are provided, as are kits and integrated systems including the nucleotide incorporating enzyme variants.

    Abstract translation: 提供了具有改进性质的包含在多核苷酸合成中利用非天然或罕见的核苷酸类似物的能力的纳入酶变体的核苷酸。 提供了产生此类核苷酸掺入酶变体的方法，以及包括核苷酸掺入酶变体的试剂盒和整合系统。

    HIGH THROUGHPUT MASS SPECTROMETRY
    7.
    发明申请
    HIGH THROUGHPUT MASS SPECTROMETRY 审中-公开
    高通量质谱

    公开(公告)号：WO0048004A9

    公开(公告)日：2001-09-27

    申请号：PCT/US0003686

    申请日：2000-02-11

    Applicant: MAXYGEN INC ,  RAILLARD SUN AI ,  CHEN YONG HONG ,  KREBBER CLAUS ,  MINSHULL JEREMY ,  STEMMER WILLEM P C

    Inventor： RAILLARD SUN AI ,  CHEN YONG HONG ,  KREBBER CLAUS ,  MINSHULL JEREMY ,  STEMMER WILLEM P C

    IPC: C12N15/52 ,  C12P1/00 ,  C12Q1/00 ,  C12Q1/02 ,  G01N33/543 ,  G01N33/68 ,  H01J49/04 ,  G01N30/72

    CPC classification number: C12Q1/00 ,  C12N15/52 ,  C12P1/00 ,  C12Q1/02 ,  G01N33/54326 ,  G01N33/68 ,  H01J49/04

    Abstract: Apparatus and methods for high throughput mass spectrometry are provided. The methods involve sample preparation in an off-line parallel purification system. Such methods include but are not limited to the use of an appropriate buffer when generating samples or the use of a solid support for tagged components. The samples prepared in this way do not then need to be column separated. The apparatus provided includes a cell growth plate for growing cells and generating products and/or reactants, an off-line parallel purification system, a mass spectrometer, and an automatic sampler that transports samples and injects them into the mass spectrometer of the apparatus. The methods and apparatus described are used, for example, in screening enzyme reaction pathways.

    Abstract translation: 提供了用于高通量质谱的装置和方法。 该方法涉及离线并行纯化系统中的样品制备。 这样的方法包括但不限于在产生样品时使用适当的缓冲液或者使用固体支持物用于标记的组分。 以这种方式制备的样品不需要进行柱分离。 提供的装置包括用于生长细胞并产生产物和/或反应物的细胞生长板，离线平行纯化系统，质谱仪和自动采样器，其将样品输送并注入到装置的质谱仪中。 所述的方法和装置例如用于筛选酶反应途径。

Patent Agency Ranking