公开(公告)号：WO2017040117A1

公开(公告)日：2017-03-09

申请号：PCT/US2016/048182

申请日：2016-08-23

Applicant: MEDTRONIC, INC.

Inventor： DINSMOOR, David A. ,  STANSLASKI, Scott R. ,  PETERSON, Erik J. ,  MAZANEC, Paul R.

IPC: A61N1/36 ,  A61N1/378 ,  A61N1/37

CPC classification number: A61N1/36125 ,  A61N1/36135 ,  A61N1/3718 ,  A61N1/37247 ,  A61N1/3756 ,  A61N1/378

Abstract: Techniques, devices, and systems for isolating, by isolation circuitry connected to a power source, a voltage from the power source, receiving, by sensing circuitry, the isolated voltage, receiving, by the sensing circuitry, a reference voltage from an implantable reference electrode via a reference node, and sensing, by the sensing circuitry, the biomedical signal with two or more implantable sensing electrodes using the isolated voltage with respect to the reference voltage.

Abstract translation: 技术，设备和系统，通过连接到电源的隔离电路隔离来自电源的电压，通过感测电路接收隔离电压，由感测电路接收来自可植入参考电极的参考电压 通过参考节点，并且通过感测电路使用相对于参考电压的隔离电压的两个或多个可植入感测电极感测生物医学信号。

公开(公告)号：WO2017007780A1

公开(公告)日：2017-01-12

申请号：PCT/US2016/041024

申请日：2016-07-06

Applicant: MED-EL ELEKTROMEDIZINISCHE GERAETE GMBH

Inventor： HOCHMAIR, Erwin

IPC: A61B5/01 ,  A61B5/055 ,  A61B5/12 ,  A61F2/18 ,  A61N1/05 ,  A61N1/18 ,  H04R25/00

CPC classification number: A61N1/3718 ,  A61B5/0008 ,  A61B5/0017 ,  A61B5/002 ,  A61B5/0031 ,  A61B5/01 ,  A61B5/055 ,  A61B5/12 ,  A61B5/6815 ,  A61B5/6817 ,  A61B5/686 ,  A61B5/6877 ,  A61B5/7225 ,  A61B2560/0209 ,  A61B2560/0219 ,  A61B2560/0223 ,  A61N1/0541 ,  A61N1/36036 ,  A61N1/3727 ,  G01R33/288

Abstract: A magnetic resonance imaging (MRI) telemetry arrangement and process for a cochlear implant system are described. Electrode current is measured that is induced in a cochlear implant electrode lead during an MRI process performed on an implanted patient. An MRI telemetry signal for an external telemetry sensor is then output based on the measured electrode current.

Abstract translation: 描述了用于人工耳蜗植入系统的磁共振成像（MRI）遥测装置和方法。 在对植入的患者进行的MRI过程中，测量在耳蜗植入电极引线中感应的电极电流。 然后基于测量的电极电流输出用于外部遥测传感器的MRI遥测信号。

公开(公告)号：WO2015164522A1

公开(公告)日：2015-10-29

申请号：PCT/US2015/027132

申请日：2015-04-22

Applicant: MEDTRONIC, INC.

Inventor： SELF, Shane A.

IPC: A61N1/05 ,  A61N1/14 ,  A61N1/36 ,  A61N1/37

CPC classification number: A61N1/08 ,  A61N1/0534 ,  A61N1/14 ,  A61N1/36 ,  A61N1/3605 ,  A61N1/36125 ,  A61N1/36142 ,  A61N1/3718 ,  H02H9/045

Abstract: Overvoltage protection circuitry configured to protect internal integrated circuits within an implantable device in the presence of a high voltage event such as defibrillation or electrocautery. The circuitry allows for an internal node to rise above the voltage level of the high voltage event to insure that an overvoltage protection element is triggered, even if the voltage level of the high voltage event is below the voltage trigger level of the overvoltage protection element.

Abstract translation: 过电压保护电路被配置为在存在诸如除颤或电灼的高电压事件的情况下保护可植入装置内的内部集成电路。 该电路允许内部节点升高到高电压事件的电压电平以确保过电压保护元件被触发，即使高电压事件的电压电平低于过电压保护元件的电压触发电平。

公开(公告)号：WO2015116443A1

公开(公告)日：2015-08-06

申请号：PCT/US2015/012150

申请日：2015-01-21

Applicant: MEDTRONIC, INC.

Inventor： JENISON, Troy A. ,  LEVY, Michael D. ,  RHODES, Benjamin P. ,  STANCER, Christopher C.

IPC: A61N1/37 ,  A61N1/08 ,  A61N1/39 ,  A61N1/36

CPC classification number: A61N1/3718 ,  A61M5/14276 ,  A61M2205/50 ,  A61M2210/0693 ,  A61M2210/1003 ,  A61N1/08 ,  A61N1/36142 ,  A61N1/37235 ,  A61N1/3925

Abstract: An implantable medical device implements a special mode of operation, such as a mode of electrical stimulation therapy, during conditions where there may be an increased likelihood that a device reset will occur. The implantable medical device recovers from the device reset by copying values that specify the special mode and that are stored in a non-volatile memory to an operating memory. The special mode is implemented after the device reset has occurred by using the values copied to the operating memory. One version of the special mode is an MRI mode that allows the implantable medical device to safely operate during an MRI scan. The fields of the MRI scan may trigger a device reset, but the MRI mode values are copied from the non-volatile memory to the operating memory, and the MRI mode is implemented after the reset by using the values copied to the operating memory.

Abstract translation: 可植入医疗装置在可能会出现设备复位的可能性增加的情况下实施特殊的操作模式，例如电刺激治疗的模式。 可植入医疗设备通过将指定特殊模式的值复制并存储在非易失性存储器中的操作存储器中，从设备恢复。 通过使用复制到操作存储器的值，在设备复位发生后实现特殊模式。 特殊模式的一个版本是MRI模式，其允许可植入医疗装置在MRI扫描期间安全地操作。 MRI扫描的区域可能会触发器件复位，但MRI模式值从非易失性存储器复制到操作存储器，并且通过使用复制到操作存储器的值在复位后实现MRI模式。

公开(公告)号：WO2013186118A1

公开(公告)日：2013-12-19

申请号：PCT/EP2013/061715

申请日：2013-06-06

Applicant: SAPIENS STEERING BRAIN STIMULATION B.V.

Inventor： TOL, Jeroen Jacob Arnold ,  BUDZELAAR, Franciscus Paulus Maria

IPC: A61N1/37 ,  A61N1/36 ,  G01R33/28

CPC classification number: A61N1/36142 ,  A61N1/3718 ,  G01R33/288

Abstract: The present invention relates to an electronic system (10) of an implantable medical device, comprising at least one first circuit (20), at least one tracking means, which is configured such that radio frequency bursts and/or a gradient magnetic field of a magnetic resonance imaging apparatus can be tracked, and at least one synchronizing means, whereby the synchronizing means is configured such that based on the tracked radio frequency bursts and/or the gradient magnetic field the at least one first circuit (20) and/or the electronic system (10) as a whole is synchronized with the radio frequency bursts and/or the gradient magnetic field.

Abstract translation: 本发明涉及可植入医疗装置的电子系统（10），其包括至少一个第一电路（20），至少一个跟踪装置，其被配置为使得射频突发和/或梯度磁场 可以跟踪磁共振成像装置和至少一个同步装置，由此同步装置被配置为使得基于跟踪的射频突发和/或梯度磁场，至少一个第一电路（20）和/或 整个电子系统（10）与射频突发和/或梯度磁场同步。

公开(公告)号：WO2013162958A1

公开(公告)日：2013-10-31

申请号：PCT/US2013/036867

申请日：2013-04-17

Applicant: MEDTRONIC, INC.

Inventor： JACKSON, Troy A. ,  MCCLURE, Larry C. ,  STANCER, Christopher C.

IPC: A61N1/08 ,  A61N1/37 ,  G01R33/02 ,  A61N1/39 ,  A61N1/36 ,  A61N1/372 ,  A61M5/142

CPC classification number: A61N1/08 ,  A61N1/36142 ,  A61N1/3706 ,  A61N1/3718 ,  A61N1/37211 ,  A61N1/3956 ,  G01R33/288

Abstract: A device includes a housing configured to be implanted in a patient. The device also includes a first magnetic field direction sensor located at a first location within the housing and configured to generate a signal representative of a first direction of a magnetic field at the first location, a second magnetic field direction sensor located at a second location within the housing and configured to generate a signal representative of a second direction of the magnetic field at the second location, and a magnetic field strength sensor configured to generate a signal representative of a strength of the magnetic field. The device further includes a control module configured to identify a source of the magnetic field based on at least one of the signal representative of the strength of the magnetic field and the signals representative of the first and second directions of the magnetic field.

Abstract translation: 一种装置包括被配置为植入患者体内的壳体。 该装置还包括位于壳体内的第一位置处的第一磁场方向传感器，并且被配置为产生表示第一位置处的磁场的第一方向的信号，位于第二位置处的第二位置处的第二磁场方向传感器 壳体并且被配置为产生表示第二位置处的磁场的第二方向的信号，以及被配置为产生表示磁场强度的信号的磁场强度传感器。 该装置还包括控制模块，该控制模块被配置为基于表示磁场的强度的信号中的至少一个和表示磁场的第一和第二方向的信号来识别磁场的源。

公开(公告)号：WO2013158189A1

公开(公告)日：2013-10-24

申请号：PCT/US2013/023637

申请日：2013-01-29

Applicant: MEDTRONIC, INC.

Inventor： CONROY, Mark ,  BONDHUS, Spencer M. ,  STEM, Bryan D.

IPC: A61N1/37 ,  A61N1/08

CPC classification number: A61N1/08 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718

Abstract: Medical lead bodies that are paired each include a braided conductive shield. The braided conductive shield of one lead body has a value for a physical parameter that differs from a value for the physical parameter of the second lead body. The difference in values of the physical parameter for the paired lead bodies results in a reduction in heating from exposure of the lead bodies to radiofrequency energy at electrodes associated with the lead bodies. The lead bodies may be paired by being implanted adjacently to one another. The lead bodies may be further paired by being coupled to a same distal body, such as a paddle containing the electrodes.

Abstract translation: 配对的医疗引线体包括编织导电屏蔽。 一个引线体的编织导电屏蔽具有与第二引线体的物理参数的值不同的物理参数的值。 成对引线体的物理参数的值的差异导致从铅体的暴露到与引线体相关联的电极处的射频能量的加热减少。 引线体可以通过相互植入而配对。 引线体可以通过耦合到相同的远端体，例如包含电极的桨来进一步配对。

公开(公告)号：WO2013003237A3

公开(公告)日：2013-04-18

申请号：PCT/US2012043841

申请日：2012-06-22

Applicant: BOSTON SCIENT NEUROMODULATION ,  MCDONALD MATTHEW LEE ,  VENOOK ROSS DANIEL

Inventor： MCDONALD MATTHEW LEE ,  VENOOK ROSS DANIEL

IPC: A61N1/08 ,  A61N1/375

CPC classification number: A61N1/3718 ,  A61N1/05 ,  A61N1/3752

Abstract: An implantable electrical stimulation system (500) includes a control module (504) electrically coupleable to a lead (502). The control module includes a housing (507), an electronic subassembly (530) disposed in the housing and a connector assembly (520) for receiving the lead. The connector assembly includes a port for receiving a proximal end of the lead. Connector contacts (528) are disposed in the connector assembly housing and electrically couple to the electronic subassembly. The connector contacts align with terminals (510) disposed on the lead to form an electrical connection between the connector contacts and the terminals when the proximal end of the lead is disposed in the port of the connector assembly. A disconnecting feature (580) includes a switch for electrically disabling, or at least significantly reducing, the electrical connection between the connector contacts and the electronic subassembly when the switch is opened.

Abstract translation: 可植入电刺激系统（500）包括电耦合到引线（502）的控制模块（504）。 控制模块包括壳体（507），设置在壳体中的电子组件（530）和用于接收引线的连接器组件（520）。 连接器组件包括用于接收引线的近端的端口。 连接器触点（528）设置在连接器组件壳体中并电耦合到电子组件。 当引线的近端设置在连接器组件的端口中时，连接器触头与设置在引线上的端子（510）对准，以在连接器触点和端子之间形成电连接。 断开特征（580）包括用于在开关断开时电连接或至少显着地减小连接器触点和电子子组件之间的电连接的开关。

公开(公告)号：WO2012115723A1

公开(公告)日：2012-08-30

申请号：PCT/US2012/020420

申请日：2012-01-06

Applicant: MEDTRONIC, INC. ,  ELLINGSON, Michael L.

Inventor： ELLINGSON, Michael L.

IPC: A61N1/08

CPC classification number: A61N1/3718 ,  A61N1/3688

Abstract: An implantable medical device (IMD) may be configured into a sensing only mode in which the IMD does not delivery therapy. For example, the IMD may be configured to operate in a sensing only mode to reduce the undesirable effects that may be caused by external fields, such as those generated by an MRI device. However, there may be instances, such as a change in the patients condition, in which it may be desirable to transition from the sensing only mode to a pacing mode to provide therapy. In accordance with the techniques described herein, the IMD monitors signals on one or more leads coupled to the medical device while operating in the sensing only mode and transitions to a pacing mode in response to not detecting a minimum number of signals on the one or more leads.

Abstract translation: 可植入医疗装置（IMD）可以被配置成IMD不进行递送治疗的仅感测模式。 例如，IMD可以被配置为以仅感测模式操作以减少可能由诸如由MRI设备产生的外部场的外部场引起的不期望的影响。 然而，可能存在例如患者状况的变化的情况，其中可能期望从仅感测模式转换到起搏模式以提供治疗。 根据本文描述的技术，IMD监视耦合到医疗设备的一个或多个引线上的信号，同时在仅感测模式下工作，并响应于未检测到一个或多个信号的最小数量的信号而转换到起搏模式 线索。

公开(公告)号：WO2012112490A1

公开(公告)日：2012-08-23

申请号：PCT/US2012/024972

申请日：2012-02-14

Applicant: BOSTON SCIENTIFIC NEUROMODULATION CORPORATION ,  MURTONEN, Salomo

Inventor： MURTONEN, Salomo

IPC: A61N1/16 ,  A61N1/375

CPC classification number: A61N1/3754 ,  A61N1/025 ,  A61N1/0551 ,  A61N1/36125 ,  A61N1/3718 ,  A61N1/3758 ,  A61N1/3787 ,  H01G4/35

Abstract: An implantable control module for an electrical stimulation system includes an electronic subassembly disposed in a sealed conductive housing. A plurality of feedthrough pins extend through the sealed housing and couple connector contact of an external connector to the electronic subassembly. Each of the plurality of conductive pathways electrically couples a different one of the plurality of feedthrough pins to the electronic subassembly. A ground line electrically couples the electronic subassembly to the housing. A capacitive flex circuit is disposed in the housing and couples to each of the feed through pins. For each of the plurality of feedthrough pins the capacitive flex circuit includes a first conductive path electrically coupling the feedthrough pin to a corresponding conductive pathway of the plurality of conductive pathways, and a second conductive path electrically coupling the feedthrough pin to the ground pin.

Abstract translation: 一种用于电刺激系统的可植入控制模块包括设置在密封导电壳体中的电子组件。 多个馈通销延伸穿过密封的壳体并将外部连接器的连接器触头耦合到电子子组件。 多个导电路径中的每一个将多个馈通引脚中的不同的引线电耦合到电子子组件。 地线将电子组件电耦合到壳体。 电容式柔性电路设置在壳体中并且耦合到每个馈通引脚。 对于多个馈通引脚中的每一个，电容性柔性电路包括将馈通引脚电耦合到多个导电路径中的对应导电路径的第一导电路径，以及将馈通引脚电连接到接地引脚的第二导电路径。