公开(公告)号：WO2007092364A3

公开(公告)日：2008-12-11

申请号：PCT/US2007002994

申请日：2007-02-02

Applicant: MERCK & CO INC ,  RAGHAVAN SUBHAREKHA ,  SCHMIDT DARBY RYE ,  COLLETTI STEVEN L ,  SMENTON ABIGAIL LEE

Inventor： RAGHAVAN SUBHAREKHA ,  SCHMIDT DARBY RYE ,  COLLETTI STEVEN L ,  SMENTON ABIGAIL LEE

IPC: C07D513/02 ,  A61K31/195 ,  A61K31/42 ,  A61K31/44 ,  C07D257/04 ,  C07D277/12 ,  C07D413/02

CPC classification number: C07C235/34 ,  C07C233/52 ,  C07C2601/16 ,  C07D211/78 ,  C07D213/55 ,  C07D213/61 ,  C07D277/30 ,  C07D333/24 ,  C07D401/04 ,  C07D413/04

Abstract: The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.

Abstract translation: 本发明包括可用于治疗动脉粥样硬化，血脂异常等的式I化合物及其药学上可接受的盐和水合物。 还包括药物组合物和使用方法。

公开(公告)号：WO2007092364A2

公开(公告)日：2007-08-16

申请号：PCT/US2007/002994

申请日：2007-02-02

Applicant: MERCK & CO., INC. ,  RAGHAVAN, Subharekha ,  SCHMIDT, Darby, Rye ,  COLLETTI, Steven, L. ,  SMENTON, Abigail, Lee

Inventor： RAGHAVAN, Subharekha ,  SCHMIDT, Darby, Rye ,  COLLETTI, Steven, L. ,  SMENTON, Abigail, Lee

CPC classification number: C07C235/34 ,  C07C233/52 ,  C07C2601/16 ,  C07D211/78 ,  C07D213/55 ,  C07D213/61 ,  C07D277/30 ,  C07D333/24 ,  C07D401/04 ,  C07D413/04

Abstract: The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.

Abstract translation: 本发明包括可用于治疗动脉粥样硬化，血脂异常等的式I化合物及其药学上可接受的盐和水合物。 还包括药物组合物和使用方法。

公开(公告)号：WO2007002557A1

公开(公告)日：2007-01-04

申请号：PCT/US2006/024740

申请日：2006-06-26

Applicant: MERCK & CO., INC. ,  RAGHAVAN, Subharekha ,  COLLETTI, Steven, L. ,  DING, Fa-Xiang ,  SHEN, Hong ,  TATA, James, R. ,  LINS, Ashley Rouse ,  SMENTON, Abigail Lee ,  CHEN, Weichun ,  SCHMIDT, Darby Rye ,  TRIA, George Scott

Inventor： RAGHAVAN, Subharekha ,  COLLETTI, Steven, L. ,  DING, Fa-Xiang ,  SHEN, Hong ,  TATA, James, R. ,  LINS, Ashley Rouse ,  SMENTON, Abigail Lee ,  CHEN, Weichun ,  SCHMIDT, Darby Rye ,  TRIA, George Scott

IPC: A61K31/196 ,  A61K31/33 ,  C07C233/45 ,  C07C233/46 ,  C07D231/12 ,  C07D249/06 ,  C07D257/04 ,  C07D261/20 ,  C07D271/06 ,  C07D277/30 ,  C07D309/28 ,  C07D401/04 ,  C07D413/04 ,  C07D417/04 ,  C07D513/04

CPC classification number: C07D261/20 ,  C07C233/52 ,  C07C233/55 ,  C07C235/36 ,  C07C237/20 ,  C07C2601/10 ,  C07C2601/16 ,  C07D231/12 ,  C07D249/06 ,  C07D249/08 ,  C07D257/04 ,  C07D271/06 ,  C07D277/30 ,  C07D307/79 ,  C07D309/14 ,  C07D309/28 ,  C07D401/04 ,  C07D413/04 ,  C07D417/04 ,  C07D513/04

Abstract: The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.

Abstract translation: 本发明包括式（I）化合物及其药学上可接受的盐和水合物，其可用于治疗动脉粥样硬化，血脂异常等。 药物组合物和使用方法也包括在内。