公开(公告)号：WO2012117350A1

公开(公告)日：2012-09-07

申请号：PCT/IB2012/050929

申请日：2012-02-28

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH ,  KEUPP, Jochen ,  VAN DEN BRINK, Johan Samuel ,  HARVEY, Paul Royston

Inventor： KEUPP, Jochen ,  VAN DEN BRINK, Johan Samuel ,  HARVEY, Paul Royston

IPC: G01R33/561 ,  G01R33/56 ,  G01R33/36

CPC classification number: G01R33/54 ,  G01R33/32 ,  G01R33/34076 ,  G01R33/3614 ,  G01R33/5605 ,  G01R33/5612 ,  G01R33/5659

Abstract: The invention relates to a method of MR imaging of at least a portion of a body (110) of a patient placed in an examination volume of a MR device, the method comprising the steps of: - subjecting the portion of the body (110) to an imaging sequence comprising at least one RF pulse, the RF pulse being transmitted toward the portion of the body (110) via a RF coil arrangement (109) to which RF signals are supplied by two or more RF power amplifiers the RF power amplifiers being activated alternately during the imaging sequence in a time -multiplexed fashion, wherein the imaging sequence requires a RF duty cycle and/or a RF pulse duration exceeding the specification of at least one of the RF power amplifiers; - acquiring MR signals from the portion of the body (110); and - reconstructing a MR image from the acquired MR signals. Moreover, the invention relates to a method of MR spectroscopy involving the alternating use of RF power amplifiers in a time -multiplexed fashion.

Abstract translation: 本发明涉及放置在MR装置的检查体积中的患者的身体（110）的至少一部分的MR成像方法，该方法包括以下步骤： - 对身体（110）的部分进行处理， 涉及包括至少一个RF脉冲的成像序列，所述RF脉冲经由RF线圈装置（109）朝向身体（110）的部分传输，RF信号由两个或更多个RF功率放大器提供给RF功率放大器 在成像序列期间以时间复用方式交替激活，其中成像序列需要超过RF功率放大器中的至少一个的RF占空比和/或RF脉冲持续时间; - 从身体（110）的部分获取MR信号; 以及 - 从所获取的MR信号重建MR图像。 此外，本发明涉及涉及以时间复用方式交替使用RF功率放大器的MR光谱的方法。

公开(公告)号：WO2010143103A1

公开(公告)日：2010-12-16

申请号：PCT/IB2010/052476

申请日：2010-06-03

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  VAN DEN BRINK, Johan, Samuel

Inventor： VAN DEN BRINK, Johan, Samuel

IPC: G06F19/00

CPC classification number: G06F19/321 ,  G06F19/00

Abstract: An apparatus comprising -an imaging component for acquiring magnetic resonance images; -a storage component for storing the magnetic resonance images in a stack; -a sorting component for sorting the magnetic resonance images in the stack using machine defined meta information of the images; and -an interface for reading the ordered stack.

Abstract translation: 一种装置，包括 - 用于获取磁共振图像的成像部件; - 用于将磁共振图像存储在堆叠中的存储部件; - 用于使用所述图像的机器定义的元信息对所述堆叠中的磁共振图像进行排序的分类部件; 和 - 用于读取有序堆栈的接口。

公开(公告)号：WO2006067679A3

公开(公告)日：2006-10-05

申请号：PCT/IB2005054218

申请日：2005-12-13

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  VAN DEN BRINK JOHAN SAMUEL ,  BENSCHOP FRANCISCUS JOHANNES M

Inventor： VAN DEN BRINK JOHAN SAMUEL ,  BENSCHOP FRANCISCUS JOHANNES M

IPC: G01R33/54

CPC classification number: G01R33/54

Abstract: A magnetic resonance imaging system comprises an RF-excitation module to generate one of several RF-excitations and a gradient module to generate one of several magnetic gradient pulses, a control unit controls the RF-excitation module and the gradient module and performs an acquisition sequence containing a succession of RF-excitations and gradient pulses. The acquisition sequence comprising several acquisition segments in which magnetic resonance signals are generated, in respective segments different contrast types occur. Individual acquisition segments have one or several repetitive acquisition units, magnetic resonance signals in an individual acquisition unit pertaining to the same contrast type. This approach of acquisition of different contrast type per group of acquisition segments allows optimisation of the acquisition of each of the contrast type independently of the contrast type of other groups of acquisition segments.

Abstract translation: 磁共振成像系统包括用于产生几个RF激发之一的RF激励模块和用于产生几个磁梯度脉冲之一的梯度模块，控制单元控制RF激励模块和梯度模块并执行采集序列 包含一系列射频激发和梯度脉冲。 采集序列包括产生磁共振信号的几个采集段，在各个段中出现不同的对比度类型。 单个采集段具有一个或几个重复采集单元，属于相同对比度类型的单独采集单元中的磁共振信号。 这种采集每组采集段不同对比度类型的方法允许独立于其他采集段组的对比度类型优化每种对比度的采集。

公开(公告)号：WO2006067679A2

公开(公告)日：2006-06-29

申请号：PCT/IB2005/054218

申请日：2005-12-13

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  VAN DEN BRINK, Johan Samuel ,  BENSCHOP, Franciscus Johannes Maria

Inventor： VAN DEN BRINK, Johan Samuel ,  BENSCHOP, Franciscus Johannes Maria

CPC classification number: G01R33/54

Abstract: A magnetic resonance imaging system comprises an RF-excitation module to generate one of several RF-excitations and a gradient module to generate one of several magnetic gradient pulses, a control unit controls the RF-excitation module and the gradient module and performs an acquisition sequence containing a succession of RF-excitations and gradient pulses. The acquisition sequence comprising several acquisition segments in which magnetic resonance signals are generated, in respective segments different contrast types occur. Individual acquisition segments have one or several repetitive acquisition units, magnetic resonance signals in an individual acquisition unit pertaining to the same contrast type. This approach of acquisition of different contrast type per group of acquisition segments allows optimisation of the acquisition of each of the contrast type independently of the contrast type of other groups of acquisition segments.

Abstract translation: 磁共振成像系统包括用于生成若干RF激励之一的RF激励模块和用于生成若干磁梯度脉冲中的一个的梯度模块，控制单元控制RF激励模块和 梯度模块并执行包含一系列RF激励和梯度脉冲的采集序列。 该采集序列包括产生磁共振信号的多个采集段，在相应的段中出现不同的对比度类型。 单个采集段具有一个或多个重复采集单元，单个采集单元中的磁共振信号属于相同的对比类型。 这种采集每组采集段不同对比度类型的方法允许独立于其他采集段组的对比度类型来优化每种对比度类型的采集。

公开(公告)号：WO2012063158A1

公开(公告)日：2012-05-18

申请号：PCT/IB2011/054818

申请日：2011-10-31

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  VAN DEN BRINK, Johan Samuel

Inventor： VAN DEN BRINK, Johan Samuel

IPC: A61N5/10

CPC classification number: A61N5/1039 ,  A61B5/055 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1081 ,  A61N2005/1055 ,  G01R33/4808

Abstract: A therapeutic apparatus (100) comprising: a radio therapy apparatus (102) for treating a target zone (146) of a subject (144), wherein the radio therapy apparatus comprises a radio therapy source (110) for generating electromagnetic radiation (114), wherein the radio therapy apparatus is adapted for rotating the radio therapy source about a rotational point (116); a mechanical actuator (104) for supporting the radio therapy apparatus and for moving the position and/or orientation of the rotational point; and a magnetic resonance imaging system (106) for acquiring magnetic resonance data (170) from an imaging zone (138), wherein the target zone is within the imaging zone, wherein the magnetic resonance imaging system comprises a magnet (122) for generating a magnetic field within the imaging zone, wherein the radio therapy source is adapted for rotating at least partially about the magnet.

Abstract translation: 一种治疗装置，包括：用于治疗受检者（144）的目标区域（146）的放射治疗装置（102），其中所述放射治疗装置包括用于产生电磁辐射（114）的放射治疗源（110） ，其中所述放射治疗装置适于围绕旋转点（116）旋转所述放射治疗源; 用于支撑所述无线电治疗装置并用于移动所述旋转点的位置和/或取向的机械致动器（104） 以及用于从成像区域（138）获取磁共振数据（170）的磁共振成像系统（106），其中所述目标区域在所述成像区域内，其中所述磁共振成像系统包括磁体（122），用于产生 所述成像区内的磁场，其中所述无线电治疗源适于至少部分地绕所述磁体旋转。

公开(公告)号：WO2012059845A1

公开(公告)日：2012-05-10

申请号：PCT/IB2011/054771

申请日：2011-10-26

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH ,  VAN DEN BRINK, Johan Samuel ,  GRAESSLIN, Ingmar ,  KRUEGER, Sascha ,  WEISS, Steffen ,  VERNICKEL, Peter

Inventor： VAN DEN BRINK, Johan Samuel ,  GRAESSLIN, Ingmar ,  KRUEGER, Sascha ,  WEISS, Steffen ,  VERNICKEL, Peter

IPC: G01R33/44

CPC classification number: G01R33/36 ,  G01R33/246 ,  G01R33/44 ,  G01R33/5612 ,  G01R33/583

Abstract: The invention relates to a method of characterizing the RF transmit chain of a magnetic resonance imaging scanner (1) using -a local transmit/receive coil system (204; 210), comprising a first local NMR probe and a first local magnetic resonance coil, the first NMR probe being spatially located in immediate neighborhood to the first coil, -a local receive coil system (206; 208), comprising a second local NMR probe and a second local magnetic resonance coil, the second NMR probe being spatially located in immediate neighborhood to the second coil, wherein the transmit chain comprises an external MR coil (9; 11; 12; 13), the method comprising: -determining with the first magnetic resonance coil, a first MR signal phase evolution of the local RF transmit field generated by MR excitation of the first probe using the first magnetic resonance coil by measuring the RF response of the first probe upon said excitation, -determining with the second magnetic resonance coil a second MR signal phase evolution of the local RF transmit field generated by MR excitation of the second probe using the external MR coil (9; 11; 12; 13) by measuring the RF response of the second probe upon said excitation, - calculating a phase offset between the first and second MR signal phase evolution.

Abstract translation: 本发明涉及一种使用本地发射/接收线圈系统（204; 210）来表征磁共振成像扫描仪（1）的RF发射链的方法，该系统包括第一局部NMR探针和第一局部磁共振线圈， 空间上位于第一线圈附近的第一NMR探针 - 局部接收线圈系统（206; 208），包括第二局部NMR探针和第二局部磁共振线圈，所述第二NMR探针在空间上位于立即 邻近于所述第二线圈，其中所述发射链包括外部MR线圈（9; 11; 12; 13），所述方法包括： - 利用所述第一磁共振线圈确定所述本地RF发射场的第一MR信号相位演变 通过在所述激发时测量第一探针的RF响应，使用第一磁共振线圈通过MR激发而产生的第一探针， - 用第二磁共振线圈确定第二MR信号phas 使用外部MR线圈（9; 9）的第二探针的MR激发产生的局部RF发射场的演变。 11; 12; 13）通过在所述激励时测量第二探针的RF响应， - 计算第一和第二MR信号相位演化之间的相位偏移。

公开(公告)号：WO2011148300A1

公开(公告)日：2011-12-01

申请号：PCT/IB2011/052195

申请日：2011-05-19

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  VAN DEN BRINK, Johan, Samuel

Inventor： VAN DEN BRINK, Johan, Samuel

IPC: G01R33/28 ,  G01R33/561

CPC classification number: G01R33/3852 ,  G01R33/285 ,  G01R33/288 ,  G01R33/54 ,  G01R33/5613

Abstract: An magnetic resonance examination system for examination of an object comprises an RF system to generate an RF transmission field and gradient system to generate temporarymagnetic gradient fields. A controlmodule includes a sequence controller to controlthe RF system and the gradient system to produce acquisition sequences including RF pulses and magnetic gradient pulses to generate magnetic resonance signals. The sequence controller is configured to produce an detection scan including a steady state gradient echo acquisition sequence to generate steady state gradient echo signals and an RF spoiled echo acquisition sequence to produce RF spoiled echo signals. The control module further including an analysis unit to compare the gradient echo signals to the RF spoiled echo signals and for detection of an instrument in the object from the comparison of the gradient echoes and the RF spoiled echoes.

Abstract translation: 用于检查物体的磁共振检查系统包括用于产生RF传输场的RF系统和用于产生临时磁梯度场的梯度系统。 控制模块包括控制RF系统和梯度系统以产生包括RF脉冲和磁梯度脉冲以产生磁共振信号的采集序列的序列控制器。 序列控制器被配置为产生包括稳态梯度回波采集序列的检测扫描，以产生稳态梯度回波信号和RF损坏回波采集序列以产生RF损坏的回波信号。 控制模块还包括分析单元，用于将梯度回波信号与RF损坏的回波信号进行比较，并且用于通过梯度回波和RF损坏回波的比较来检测物体中的仪器。

公开(公告)号：WO2011101765A1

公开(公告)日：2011-08-25

申请号：PCT/IB2011/050480

申请日：2011-02-04

Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  VAN DEN BRINK, Johan Samuel

Inventor： VAN DEN BRINK, Johan Samuel

IPC: G01R33/28

CPC classification number: G01R33/281 ,  G01R33/282 ,  G01R33/5601

Abstract: A dispenser is provided for producing a nuclear hyperpolarised contrast agent. The dispenser comprises a chamber to receive a compound. A photonic hyperpolarisation system generates an OAM -photonic beam endowed with orbital angular momentum and is arranged to direct the OAM -photonic beam into the chamber so as to generate nuclear hyperpolarisation in the compound. The chamber has an output over which the hyperpolarised compound can be issued. Since the hyperpolarisation is generated ex-vivo, the penetration depth of the OAM-photonic beam in biological tissue is irrelevant for the present invention.

Abstract translation: 提供分配器用于生产核超极化造影剂。 分配器包括容纳化合物的室。 光子超极化系统产生具有轨道角动量的OAM-光子束，并被布置成将OAM-光子束引导到室中，以在化合物中产生核超极化。 该室具有可以发出超极化化合物的输出。 由于超极化是离体产生的，所以OAM光子束在生物组织中的穿透深度与本发明无关。