公开(公告)号：WO2020180230A1

公开(公告)日：2020-09-10

申请号：PCT/SE2020/050225

申请日：2020-02-28

申请人： XU, Weidong ,  GAO, Feng

发明人： XU, Weidong ,  GAO, Feng

IPC分类号： H01L29/167 ,  C01G23/04 ,  H01L31/0288

摘要： The present invention relates to optoelectronic devices based on a perovskite material comprising organic passivation agents for reducing unwanted recombination effects and to a method of producing such.In particular the invention relates to PeLED with exceptional high EQE up to 21.6%.

公开(公告)号：WO2010085633A1

公开(公告)日：2010-07-29

申请号：PCT/US2010/021788

申请日：2010-01-22

申请人： VERIVUE, INC. ,  BRANAM, Steve ,  FRINK, Craig ,  KRISHNAN, Santosh ,  XU, Weidong ,  ZHOU, Jean ,  ZHU, Qin-Fan

发明人： BRANAM, Steve ,  FRINK, Craig ,  KRISHNAN, Santosh ,  XU, Weidong ,  ZHOU, Jean ,  ZHU, Qin-Fan

IPC分类号： H04N7/24

CPC分类号： H04N21/44016 ,  H04N21/23424 ,  H04N21/23611

摘要： Described are computer-based methods and apparatuses, including computer program products, for scalable seamless digital video stream splicing. Data packets in a first video stream of bits are rearranged. Placeholder packets are created in a second video stream of bits. The first video stream of bits and the second video stream of bits are combined to generate a spliced stream by inserting data packets from the first video stream of bits into the placeholder packets in the second video stream of bits.

摘要翻译： 描述了基于计算机的方法和装置，包括用于可扩展无缝数字视频流拼接的计算机程序产品。 第一视频流中的数据包被重新排列。 在第二个视频流中创建占位符数据包。 比特的第一视频流和第二视频流比特流被组合以通过将来自比特的第一视频流的数据分组插入第二视频比特流中的占位符分组来产生拼接流。

公开(公告)号：WO2009128960A3

公开(公告)日：2010-03-11

申请号：PCT/US2009031011

申请日：2009-01-14

申请人： ULTRAPID NANODIAGNOSTICS INC ,  XU WEIDONG ,  MOHAPATRA SHYAM ,  KUMAR ARUN

发明人： XU WEIDONG ,  MOHAPATRA SHYAM ,  KUMAR ARUN

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6834 ,  C12Q1/6804 ,  C12Q2565/518 ,  C12Q2563/161 ,  C12Q2565/625 ,  C12Q2563/131

摘要： A rapid test kit may have a genetic probe, and antibody detecting probe or a combination of a genetic probe and an antibody detecting probe disposed within one or more test windows of the test kit. A cellulose filter paper membrane with a flow rate selected in a range of about 0.04 to about 0.4 ml/min/cm2 is used in one example, The test kit provides for rapid screening for DNA, RNA or fragments of DNA or RNA in a bodily fluid or antibodies indicating exposure to such DNA/RNA. The genetic probe may include single stranded DNA or a fragment of single stranded DNA, such as primer, immobilized on the filter paper, and a single stranded DNA, such as the same or a different primer, conjugated with a marker, such as a nanotube or nanoparticle. For example, a gold nanoparticle or a carbon nanotube may be used as a staining agent by conjugating the gold nanoparticle or the carbon nanotube to a genetic probe, such as a DNA primer capable of binding with a complementary DNA or viral RNA or a fratment of one of these. By comparing contrast or intensity of a test spot to a standard, a viral load may be reported. By comparing a test region using the genetic marker and a test region using an antigen to detect antibodies, a sensitive and specific test may be conducted during use of a vaccine to determine the effectiveness of the vaccine, for example.

摘要翻译： 快速测试试剂盒可以具有遗传探针和抗体检测探针，或者位于测试试剂盒的一个或多个测试窗口内的遗传探针和抗体检测探针的组合。 在一个实施例中使用流量选择在约0.04至约0.4ml / min / cm 2范围内的纤维素滤纸膜。测试试剂盒提供对身体的DNA，RNA或DNA或RNA片段的快速筛选 表明暴露于这种DNA / RNA的液体或抗体。 遗传探针可以包括固定在滤纸上的单链DNA或单链DNA片段，例如引物，以及与标记物如纳米管缀合的单链DNA，例如相同或不同的引物 或纳米颗粒。 例如，金纳米颗粒或碳纳米管可以通过将金纳米颗粒或碳纳米管与遗传探针（例如能够与互补DNA或病毒RNA结合的DNA引物）或遗传探针结合的染色剂用作染色剂 其中之一。 通过将测试点的对比度或强度与标准进行比较，可以报告病毒载量。 通过比较使用遗传标记的测试区域和使用抗原的测试区域来检测抗体，例如，可以在使用疫苗期间进行敏感和特异性测试以确定疫苗的有效性。

公开(公告)号：WO2007127487A3

公开(公告)日：2008-04-24

申请号：PCT/US2007010572

申请日：2007-04-30

申请人： UNIV SOUTH FLORIDA ,  MOHAPATRA SHYAM S ,  XU WEIDONG ,  KONG XIAOYUAN ,  WANG XIAOQIN

发明人： MOHAPATRA SHYAM S ,  XU WEIDONG ,  KONG XIAOYUAN ,  WANG XIAOQIN

IPC分类号： A01N43/04 ,  A61K31/70

CPC分类号： C12N15/1138 ,  C12N2310/14

摘要： This invention pertains to inhibitors of atrial natriuretic peptide receptor A (NPRA) function, such as small interfering RNA (siRNA), useful for reducing the inflammation associated with many human diseases, such as asthma, respiratory syncytial virus (RSV) infection, and cancers (such as melanoma, lung cancer, and/or ovarian cancer) by interfering with NPRA gene expression or otherwise reducing NPRA function within a subject; and methods for treating a subject suffering from, or at risk of developing, an inflammatory disease, respiratory allergy (such as allergic rhinitis and asthma), viral infection, and/or cancer by administering such NPRA inhibitors to the subject.

摘要翻译： 本发明涉及用于减少与诸如哮喘，呼吸道合胞病毒（RSV）感染和癌症相关的许多人类疾病的炎症的小干扰RNA（siRNA）的心房钠尿肽受体A（NPRA）功能的抑制剂 （例如黑素瘤，肺癌和/或卵巢癌）通过干扰NPRA基因表达或以其他方式降低受试者内的NPRA功能; 以及通过向受试者施用这种NPRA抑制剂来治疗患有或有风险发展为炎性疾病，呼吸性过敏（例如过敏性鼻炎和哮喘），病毒感染和/或癌症的受试者的方法。

公开(公告)号：WO2009128960A2

公开(公告)日：2009-10-22

申请号：PCT/US2009/031011

申请日：2009-01-14

申请人： ULTRAPID NANODIAGNOSTICS, INC. ,  XU, Weidong ,  MOHAPATRA, Shyam ,  KUMAR, Arun

发明人： XU, Weidong ,  MOHAPATRA, Shyam ,  KUMAR, Arun

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6834 ,  C12Q1/6804 ,  Y02A50/55 ,  C12Q2565/518 ,  C12Q2563/161 ,  C12Q2565/625 ,  C12Q2563/131

摘要： A rapid test kit may have a genetic probe, and antibody detecting probe or a combination of a genetic probe and an antibody detecting probe disposed within one or more test windows of the test kit. A cellulose filter paper membrane with a flow rate selected in a range of about 0.04 to about 0.4 ml/min/cm2 is used in one example, The test kit provides for rapid screening for DNA, RNA or fragments of DNA or RNA in a bodily fluid or antibodies indicating exposure to such DNA/RNA. The genetic probe may include single stranded DNA or a fragment of single stranded DNA, such as primer, immobilized on the filter paper, and a single stranded DNA, such as the same or a different primer, conjugated with a marker, such as a nanotube or nanoparticle. For example, a gold nanoparticle or a carbon nanotube may be used as a staining agent by conjugating the gold nanoparticle or the carbon nanotube to a genetic probe, such as a DNA primer capable of binding with a complementary DNA or viral RNA or a fratment of one of these. By comparing contrast or intensity of a test spot to a standard, a viral load may be reported. By comparing a test region using the genetic marker and a test region using an antigen to detect antibodies, a sensitive and specific test may be conducted during use of a vaccine to determine the effectiveness of the vaccine, for example.

摘要翻译： 快速测试试剂盒可以具有遗传探针和抗体检测探针，或者位于测试试剂盒的一个或多个测试窗口内的遗传探针和抗体检测探针的组合。 在一个实施例中使用流量选择在约0.04至约0.4ml / min / cm 2范围内的纤维素滤纸膜。测试试剂盒提供对身体的DNA，RNA或DNA或RNA片段的快速筛选 表明暴露于这种DNA / RNA的液体或抗体。 遗传探针可以包括固定在滤纸上的单链DNA或单链DNA片段，例如引物，以及与标记物如纳米管缀合的单链DNA，例如相同或不同的引物 或纳米颗粒。 例如，金纳米颗粒或碳纳米管可以通过将金纳米颗粒或碳纳米管与遗传探针（例如能够与互补DNA或病毒RNA结合的DNA引物）或遗传探针结合的染色剂用作染色剂 其中之一。 通过将测试点的对比度或强度与标准进行比较，可以报告病毒载量。 通过比较使用遗传标记的测试区域和使用抗原的测试区域来检测抗体，例如，可以在使用疫苗期间进行敏感和特异性测试以确定疫苗的有效性。

公开(公告)号：WO2009042173A9

公开(公告)日：2009-04-02

申请号：PCT/US2008/011113

申请日：2008-09-24

申请人： UNIVERSITY OF SOUTH FLORIDA ,  MOHAPATRA, Shyam, S. ,  KONG, Xiaoyuan ,  XU, Weidong

发明人： MOHAPATRA, Shyam, S. ,  KONG, Xiaoyuan ,  XU, Weidong

IPC分类号： A61K35/24

摘要： The subject invention provides for the utilization of bone-marrow derived stem cells in the treatment of allergic and inflammatory diseases. In one embodiment, the invention provides for treatment of asthma. Bone-marrow derived stem cells can be used for decreasing inflammation and alter the course of immune response in the lung.

公开(公告)号：WO2012087670A2

公开(公告)日：2012-06-28

申请号：PCT/US2011/064641

申请日：2011-12-13

申请人： EXXONMOBIL RESEARCH AND ENGINEERING COMPANY ,  BROWN, Robert, Christopher ,  SESHADRI, Rekha ,  CHAVEZ-TORRES, Carlos ,  XU, Weidong ,  RICHARDSON, Toby

发明人： BROWN, Robert, Christopher ,  SESHADRI, Rekha ,  CHAVEZ-TORRES, Carlos ,  XU, Weidong ,  RICHARDSON, Toby

IPC分类号： C12P7/64 ,  C12N1/13

CPC分类号： C12Y301/02023 ,  C12N9/16 ,  C12P7/6418 ,  Y02P20/582

摘要： The described invention provides genetically engineered microorganisms, including photosynthetic microorganisms, expressing 4-hydroxybenzoyl-CoA thioesterases and methods of using the genetically engineered microorganisms for producing free fatty acids and/or fatty acid derivatives.

摘要翻译： 所描述的发明提供了表达4-羟基苯甲酰-CoA硫酯酶的遗传工程微生物，包括光合微生物，以及使用遗传工程微生物产生游离脂肪酸和/或脂肪酸衍生物的方法。

公开(公告)号：WO2010099192A1

公开(公告)日：2010-09-02

申请号：PCT/US2010/025218

申请日：2010-02-24

申请人： VERIVUE, INC. ,  BRANAM, Steve ,  FRINK, Craig ,  HLUCHYJ, Michael, G. ,  KRISHNAN, Santosh ,  POND, Daniel ,  RADOGNA, Thomas, V. ,  XU, Weidong ,  ZHU, Qin-Fan

发明人： BRANAM, Steve ,  FRINK, Craig ,  HLUCHYJ, Michael, G. ,  KRISHNAN, Santosh ,  POND, Daniel ,  RADOGNA, Thomas, V. ,  XU, Weidong ,  ZHU, Qin-Fan

IPC分类号： G06F17/30

CPC分类号： H04N21/26258 ,  H04N21/23424 ,  H04N21/4622 ,  H04N21/6405 ,  H04N21/64322

摘要： Described are computer-based methods and apparatuses, including computer program products, for input queued content switching using a playlist. A retrieval sequence is generated using a plurality of content requests based on content location information. A first portion of content is requested to be queued at a first content source, and a second portion of content is requested to be queued at a second content source. A content stream of the first portion and the second portion of content is generated using the retrieval sequence. The generating includes selecting the first portion of content from a queue associated with the first content source and transferring the first portion of content to an output buffer, then terminating transfer of the first portion of content and initiating transfer of the second portion of content from a queue associated with the second content source. The portion of content in the output buffer is transmitted to a client device.

摘要翻译： 描述了基于计算机的方法和设备，包括计算机程序产品，用于使用播放列表进行输入排队的内容切换。 使用基于内容位置信息的多个内容请求生成检索序列。 请求内容的第一部分在第一内容源处排队，并且内容的第二部分被请求在第二内容源处排队。 使用检索顺序生成第一部分和第二部分内容的内容流。 生成包括从与第一内容源相关联的队列中选择内容的第一部分并将内容的第一部分传送到输出缓冲器，然后终止内容的第一部分的传送，并启动第二部分内容的传送 与第二内容源相关联的队列。 输出缓冲器中的内容部分被发送到客户端设备。

公开(公告)号：WO2009073527A3

公开(公告)日：2009-08-20

申请号：PCT/US2008084908

申请日：2008-11-26

申请人： UNIV SOUTH FLORIDA ,  MOHAPATRA SHYAM S ,  XU WEIDONG ,  KONG XIAOYUAN ,  WANG XIAOQIN ,  MOHAPATRA SUBHRA S

发明人： MOHAPATRA SHYAM S ,  XU WEIDONG ,  KONG XIAOYUAN ,  WANG XIAOQIN ,  MOHAPATRA SUBHRA S

IPC分类号： A61K31/7088 ,  A61K31/722 ,  A61P35/00 ,  C12N15/113

CPC分类号： C12N15/1138 ,  A61K9/0019 ,  A61K9/0034 ,  A61K9/0043 ,  A61K9/0073 ,  A61K9/5161 ,  A61K31/711 ,  A61K31/713 ,  A61K47/61 ,  A61K47/6935 ,  A61K47/6939 ,  A61K48/0008 ,  A61K48/005 ,  A61K49/0008 ,  B82Y5/00 ,  C12N2310/11 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2320/30

摘要： Methods, compositions and devices are provided by the present invention for reducing activity of a natriuretic peptide receptor and other signals. Therapeutic treatments are provided by use of polynucleotides encoding a natriuretic peptide or by regulating the expression of natriuretic peptide receptor, such as NPRA and NPRC, or combinations of these therapies. Routes used for delivering polynucleotides encoding a natriuretic peptide, or, for example, siRNA that down regulates natriuretic peptide receptor include subcutaneous injection, oral gavage, transdermal and intranasal delivery routes. Compositions can include chitosan. chitosan derivatives, and chitosan derivative and a lipid. Transdermal delivery can use a transdermal cream. Intranasal delivery can use a dropper or an aspirator for delivery of a mist. Oral gavage delivers equivalent to oral delivery. Delivery permits cell and tissue specific targeting of gene therapies resulting in expression of a natriuretic peptide or down regulation of natriuretic peptide receptor. A variety of cancers, asthma and viral diseases can be treated therapeutically using the methods and compositions of the present invention.

摘要翻译： 本发明提供了用于降低利尿钠肽受体和其他信号的活性的方法，组合物和装置。 通过使用编码利钠肽的多核苷酸或通过调节利钠肽受体如NPRA和NPRC的表达或这些疗法的组合来提供治疗性治疗。 用于递送编码利钠肽的多核苷酸，或例如下调利钠肽受体的siRNA的途径包括皮下注射，口腔管饲法，经皮和鼻内递送途径。 组合物可以包括壳聚糖。 壳聚糖衍生物和壳聚糖衍生物和脂质。 透皮递送可以使用透皮乳膏。 鼻内输送可以使用滴管或吸气器输送雾气。 口服灌胃相当于口服递送。 递送允许基因疗法的细胞和组织特异性靶向导致利钠肽的表达或利钠肽受体的下调。 使用本发明的方法和组合物可治疗各种癌症，哮喘和病毒性疾病。

公开(公告)号：WO2007127487A2

公开(公告)日：2007-11-08

申请号：PCT/US2007/010572

申请日：2007-04-30

申请人： UNIVERSITY OF SOUTH FLORIDA ,  MOHAPATRA, Shyam, S. ,  XU, Weidong ,  KONG, Xiaoyuan ,  WANG, Xiaoqin

发明人： MOHAPATRA, Shyam, S. ,  XU, Weidong ,  KONG, Xiaoyuan ,  WANG, Xiaoqin

IPC分类号： C07H21/04 ,  C12P21/06 ,  C12N5/10 ,  C12P21/08

CPC分类号： C12N15/1138 ,  C12N2310/14

摘要： This invention pertains to inhibitors of atrial natriuretic peptide receptor A (NPRA) function, such as small interfering RNA (siRNA), useful for reducing the inflammation associated with many human diseases, such as asthma, respiratory syncytial virus (RSV) infection, and cancers (such as melanoma, lung cancer, and/or ovarian cancer) by interfering with NPRA gene expression or otherwise reducing NPRA function within a subject; and methods for treating a subject suffering from, or at risk of developing, an inflammatory disease, respiratory allergy (such as allergic rhinitis and asthma), viral infection, and/or cancer by administering such NPRA inhibitors to the subject.

摘要翻译： 本发明涉及用于减少与诸如哮喘，呼吸道合胞病毒（RSV）感染和癌症相关的许多人类疾病的炎症的小干扰RNA（siRNA）的心房钠尿肽受体A（NPRA）功能的抑制剂 （例如黑素瘤，肺癌和/或卵巢癌）通过干扰NPRA基因表达或以其他方式降低受试者内的NPRA功能; 以及通过向受试者施用这种NPRA抑制剂来治疗患有或有风险发展为炎性疾病，呼吸性过敏（例如过敏性鼻炎和哮喘），病毒感染和/或癌症的受试者的方法。