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公开(公告)号：WO2010142137A1
公开(公告)日：2010-12-16
申请号：PCT/CN2010/000760
申请日：2010-05-28
Applicant: 江苏恒瑞医药股份有限公司 , 上海恒瑞医药有限公司 , 邓炳初 , 吕贺军 , 费洪博 , 陈一千
IPC: A61K31/655 , C07D231/46 , C07D405/12 , C07D409/12 , A61P7/00 , A61P7/04
CPC classification number: C07D231/46 , A61K31/4152 , A61K31/4155 , A61K45/06 , C07C211/05 , C07C211/27 , C07C215/08 , C07C215/10 , C07C215/40 , C07C279/14 , C07D295/027 , C07D405/12 , C07D409/12
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公开(公告)号：WO2009092276A1
公开(公告)日：2009-07-30
申请号：PCT/CN2009/000001
申请日：2009-01-04
IPC: C07D231/20 , C07D307/79 , C07D311/04 , A61K31/4152 , A61K31/343 , A61K31/352 , A61K31/655 , A61P7/00
CPC classification number: C07D417/12 , C07D231/08 , C07D231/22 , C07D231/38 , C07D403/12 , C07D405/04 , C07D405/10 , C07D405/12 , C07D409/12
Abstract: The bicycle-substituted pyrazolon-azo derivatives of formula (I) or pharmaceutical acceptable salts, hydrates or solvates thereof, methods for their preparation, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as thrombopoietin (TPO) mimetics and their use as agonists of thrombopoietin receptor. The definitions of substituents of formula (I) are the same as the description.
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公开(公告)号：WO2011140936A1
公开(公告)日：2011-11-17
申请号：PCT/CN2011/073550
申请日：2011-04-29
Applicant: 上海恒瑞医药有限公司 , 江苏恒瑞医药股份有限公司 , 吕贺军 , 邓炳初 , 陈一千 , 王胜蓝 , 王华 , 张蕾 , 李军
IPC: C07D209/96 , C07D413/06 , A61K31/4035 , A61P9/00 , A61P11/00 , A61P35/00
CPC classification number: C07D209/96 , A61K31/4035 , C07D413/06
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公开(公告)号：WO2009103218A8
公开(公告)日：2009-08-27
申请号：PCT/CN2009/000136
申请日：2009-02-06
IPC: C07D207/263 , C07D209/14 , C07D231/22 , C07D403/12 , C07C243/38 , C07D257/04 , A61K31/4015 , A61K31/4152 , A61K31/4155 , A61P7/04 , A61P43/00
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