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公开(公告)号：WO2005115341A3
公开(公告)日：2005-12-08
申请号：PCT/US2005/018797
申请日：2005-05-27
发明人： HAREL, Mordechai
摘要： The invention relates to particles suitable for oral administration of a composition to an animal. The particles comprise a substantially indigestible polymer matrix. In one embodiment, the matrix contains the composition and a lipid that is dissoluble in the animal. In another embodiment, the matrix is mixed with the composition and contained in a dissoluble coating. The lipid and coating can be ones which are preferentially dissoluble in one compartment of an animal than in another. For example, the particles can be made to preferentially release the composition in the intestines, rather than the stomach, of a mammal, a fish, or a crustacean. Examples of compounds which can be administered in such compositions include vitamins, fatty acids, oils, carotenoids, nutraceuticals, pharmaceuticals, live or dormant probiotic bacteria, hormones, nucleic acids, and proteins. The particles described herein have the further advantage that they can protect sensitive compounds from oxidation, taste or odor change, and other types of degradation.
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公开(公告)号：WO2016022532A1
公开(公告)日：2016-02-11
申请号：PCT/US2015/043564
申请日：2015-08-04
CPC分类号： A61K9/5052 , A23K20/158 , A23K40/30 , A23L29/212 , A23L29/219 , A23L29/25 , A23L29/281 , A23L29/284 , A23L33/115 , A23P10/30 , A23V2002/00 , A61K9/1652 , A61K9/5073 , A61K9/5169 , A61K31/00 , A61K31/07 , A61K35/60
摘要： A composition comprising hydrophobic droplets coated by a shell and dispersed in a matrix and a consumable product comprising the composition are provided. The hydrophobic droplets comprise a hydrophobic compound, the shell comprises an irreversibly denatured protein, and the matrix comprises a protein, a starch, and a polysaccharide. Also provided are methods for preparing the composition and the consumable product.
摘要翻译： 提供了包含由壳涂覆并分散在基质中的疏水性小滴和包含该组合物的消耗品的组合物。 疏水性液滴包含疏水性化合物，所述壳包含不可逆变性的蛋白质，所述基质包含蛋白质，淀粉和多糖。 还提供了制备组合物和消耗品的方法。
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公开(公告)号：WO2017019273A1
公开(公告)日：2017-02-02
申请号：PCT/US2016/041428
申请日：2016-07-08
发明人： KESHTMAND, Majid , HAREL, Mordechai , RICE, Tricia
CPC分类号： A23L33/125 , A23L2/52 , A23L2/66 , A23L33/135 , A23L33/18 , A23L33/185 , A23L33/40 , A23V2002/00 , A23V2200/3202 , A23V2200/3204 , A23V2250/507 , A23V2250/548 , A23V2250/612 , A23V2250/712
摘要： A dry stable probiotic composition is provided. The composition comprises one or more viable probiotic microorganisms, one or more hydrolyzed proteins, one or more disaccharides, one or more oligosaccharides, and one or more polysaccharides, but not trehalose. The composition has viability of at least 1x10 10 CFU/g, and a viability loss of less than 1 log unit/g after 3 months at a temperature of 40 °C and a relative humidity of 33%. Also provided are methods for preparing the dry stable probiotic composition.
摘要翻译： 提供干稳定的益生菌组合物。 组合物包含一种或多种活的益生菌微生物，一种或多种水解蛋白质，一种或多种二糖，一种或多种寡糖，以及一种或多种多糖，但不包括海藻糖。 该组合物在40℃的温度和33％的相对湿度下3个月后的存活率至少为1×10 10 CFU / g，存活力损失小于1log单位/ g。 还提供了制备干稳定益生菌组合物的方法。
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公开(公告)号：WO2016210103A1
公开(公告)日：2016-12-29
申请号：PCT/US2016/038978
申请日：2016-06-23
IPC分类号： A61K9/50 , A61K39/116 , A61K39/12 , A01N25/00 , A01N25/26
CPC分类号： A01N25/26 , A01N25/004 , A61K9/107 , A61K9/2813 , A61K9/282 , A61K9/2846 , A61K9/286 , A61K9/2866 , A61K9/288 , A61K31/573 , A61K39/0008 , A61K39/0275 , A61K39/107 , A61K39/116 , A61K39/12 , A61K2039/542 , A61K2039/55566 , Y02A50/472
摘要： The present invention provides compositions for delivering an active agent to an animal, comprising an active agent, a first coating, a second coating and a third coating. The active agent is coated with the first coating, the first coating is coated with the second coating, and the second coating is coated with the third coating. The active agent is in contact with the first coating, not the second or third coating. The first coating separates the active agent from the second coating while the second coating separates the first and third coatings. The first, second and third coatings are different from each other. Also provided are methods for making and using the compositions.
摘要翻译： 本发明提供了将活性剂递送至动物的组合物，其包含活性剂，第一涂层，第二涂层和第三涂层。 活性剂涂覆有第一涂层，第一涂层涂覆有第二涂层，第二涂层涂覆有第三涂层。 活性剂与第一涂层接触，而不是第二涂层或第三涂层。 第一涂层将活性剂与第二涂层分开，而第二涂层分离第一和第三涂层。 第一，第二和第三涂层彼此不同。 还提供了制备和使用组合物的方法。
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