中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

8 records (took 0.007 seconds)

    INHALATION DEVICE FOR PRODUCING A DRUG AEROSOL
    4.
    发明申请
    INHALATION DEVICE FOR PRODUCING A DRUG AEROSOL 审中-公开
    用于生产药物气溶胶的吸入装置

    公开(公告)号：WO2004050139A3

    公开(公告)日：2005-09-15

    申请号：PCT/US0332803

    申请日：2003-10-16

    Applicant: ALEXZA MOLECULAR DELIVERY CORP

    Inventor： CROSS STEPHEN ,  HODGES CRAIG C ,  HALE RON L ,  LLOYD PETER M ,  MYERS DANIEL J ,  QUINTANA REYNALDO J ,  RABINOWITZ JOSHUA D ,  TOM CURTIS ,  WENSLEY MARTIN J

    IPC: A61M11/00 ,  A61M11/04 ,  A61M15/00 ,  A61M15/06 ,  A61M16/00 ,  A61M16/10 ,  A62B7/00 ,  F23D11/00 ,  F23D14/00 ,  F24J3/00 ,  H05B3/00

    CPC classification number: A61M15/00 ,  A61M11/002 ,  A61M11/041 ,  A61M11/042 ,  A61M11/047

    Abstract: A device for delivering a drug by inhalation is disclosed. The device includes a body defining an interior flow-through chamber having upstream and downstream chamber openings, and a drug supply unit contained within the chamber for producing, upon actuation, a heated drug vapor in a condensation region of the chamber. Gas drawn through the chamber region at a selected gas-flow rate is effective to form drug condensation particles from the drug vapor having a selected MMAD between 0.02 and 0.1 MMAD or between 1 and 3.5 gm. A gas-flow control valve disposed upstream of the unit functions to limit gas-flow rate through the condensation region to the selected gas-flow rate. An actuation switch in the device activates the drug-supply unit, such that the drug-supply unit can be controlled to produce vapor when the gas-flow rate through the chamber is at the selected flow rate.

    Abstract translation: 公开了一种通过吸入传送药物的装置。 该装置包括限定具有上游和下游室开口的内部流通室的主体，以及容纳在该室内的药物供应单元，用于在致动时产生在该室的冷凝区域中的加热的药物蒸气。 以选择的气体流速通过腔室区域抽吸的气体有效地从具有0.02至0.1MMAD的选择的MMAD或1至3.5gm之间的药物蒸气形成药物凝结颗粒。 设置在单元上游的气体流量控制阀用于将通过冷凝区域的气体流量限制到所选择的气体流量。 装置中的致动开关激活药物供应单元，使得当通过腔室的气体流量处于所选择的流速时，可以控制药物供应单元产生蒸汽。

    METHOD OF FORMING AN AEROSOL FOR INHALATION DELIVERY
    5.
    发明申请
    METHOD OF FORMING AN AEROSOL FOR INHALATION DELIVERY 审中-公开
    形成用于吸入输送的气溶胶的方法

    公开(公告)号：WO02098389A8

    公开(公告)日：2006-10-12

    申请号：PCT/US0215425

    申请日：2002-05-13

    Applicant: ALEXZA MOLECULAR DELIVERY CORP

    Inventor： HALE RON L ,  HODGES CRAIG C ,  LLOYD PETER M ,  MUFSON DANIEL ,  ROGERS DANIEL D ,  SONG SOONHO ,  WENSLEY MARTIN J ,  MYERS DANIEL J ,  MCKINNEY JEFFREY A ,  QUINTANA REYNALDO J ,  RABINOWITZ JOSHUA D

    IPC: A61K9/72 ,  A61M15/00 ,  A61K9/00 ,  A61K9/16 ,  A61K31/4468 ,  A61M11/00 ,  A61M11/04 ,  A61M16/00 ,  A61P23/00 ,  B05B7/16 ,  B05B17/04

    CPC classification number: A61M11/044 ,  A61K9/007 ,  A61K9/0073 ,  A61K31/235 ,  A61K31/4468 ,  A61K31/485 ,  A61K31/519 ,  A61M11/001 ,  A61M11/02 ,  A61M15/00 ,  A61M15/0028 ,  A61M16/109 ,  A61M2016/0039 ,  A61M2205/3606 ,  A61M2205/3653 ,  A61M2205/368 ,  A61M2205/50 ,  B05B7/1686 ,  B05B17/04

    Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000 °C/s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10 µ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.

    Abstract translation: 本发明涉及含有小颗粒的气溶胶的吸入输送。 具体地说，本发明涉及形成用于吸入治疗的气雾剂的方法。 在本发明的方法方面，提供了一种形成用于吸入治疗的气雾剂的方法。 该方法包括以下步骤：（a）以大于1000℃/ s的速率加热涂覆有包含药物的组合物的基底，从而形成蒸气; 和（b）允许蒸汽冷却，从而形成用于吸入治疗的气溶胶。 在本发明的另一方法方面，提供了形成用于吸入治疗的气雾剂的方法。 该方法包括以下步骤：（a）加热涂覆有包含药物的组合物的基底以形成蒸气，其中所述涂覆的组合物为小于10μm的膜的形式; 和（b）允许蒸汽冷却，从而形成用于吸入治疗的气溶胶。 在本发明的另一方法方面，提供了形成用于吸入治疗的气雾剂的方法。 该方法包括以下步骤：（a）加热涂覆有包含药物的组合物的基底以在小于100毫秒内形成蒸气，其中蒸气的质量大于0.1mg; 和（b）允许蒸汽冷却，从而形成用于吸入治疗的气溶胶。

Patent Agency Ranking