公开(公告)号：WO2015015179A1

公开(公告)日：2015-02-05

申请号：PCT/GB2014/052306

申请日：2014-07-28

Applicant: ATLAS GENETICS LIMITED

Inventor： KENDALL TAYLOR, Jay ,  ARLETT, Ben

IPC: B01L3/00

CPC classification number: B01L3/502 ,  B01L3/502738 ,  B01L3/567 ,  B01L7/52 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2200/0673 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/123 ,  B01L2300/1883 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/06 ,  B01L2400/0622 ,  B01L2400/0638 ,  B01L2400/0655 ,  B01L2400/0683 ,  G01N1/38

Abstract: A fluidic cartridge for processing a liquid sample comprises a main channel for passing the liquid sample therethrough from an upstream end to a downstream end; and one or more branch channels that join the main channel for introducing liquid and gas into the main channel after the liquid sample has passed downstream of the one or more branch channels. The one or more branch channels including a first branch channel, wherein the first branch channel comprises: a gas inlet for introducing a gas into the first branch channel; a liquid inlet for introducing a liquid into the first branch channel; and a valve configured to move between a closed position in which it prevents liquid and gas in the first branch channel from passing into the main channel and an open position in which it permits liquid and gas in the first branch channel to pass into the main channel.

Abstract translation: 用于处理液体样品的流体盒包括用于使液体样品从上游端流到下游端的主通道; 以及一个或多个分支通道，其在液体样品已经通过一个或多个分支通道的下游之后连接主通道用于将液体和气体引入主通道。 所述一个或多个分支通道包括第一分支通道，其中所述第一分支通道包括：用于将气体引入所述第一分支通道的气体入口; 用于将液体引入到第一分支通道中的液体入口; 以及构造成在闭合位置之间移动的阀，其中其阻止第一分支通道中的液体和气体进入主通道，并且其中允许第一分支通道中的液体和气体进入主通道的打开位置 。

公开(公告)号：WO2015015177A1

公开(公告)日：2015-02-05

申请号：PCT/GB2014/052303

申请日：2014-07-28

Applicant: ATLAS GENETICS LIMITED

Inventor： KENDALL TAYLOR, Jay ,  ARLETT, Ben

IPC: B01L3/00

CPC classification number: B01L3/5027 ,  B01L3/50273 ,  B01L3/545 ,  B01L7/52 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2300/021 ,  B01L2300/06 ,  B01L2300/0645 ,  B01L2300/0672 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1883 ,  B01L2400/0481 ,  B01L2400/0655 ,  B01L2400/0683 ,  C12Q1/6806 ,  G01N35/00732 ,  G01N2035/00752 ,  G01N2035/00811

Abstract: A disposable fluidic cartridge has a recess therein. A mechanically-actuated mechanism is disposed within the recess for effecting an operation of the fluidic cartridge. The cartridge further comprises a machine-readable identification code on a breakable label covering at least a portion of the recess such that the portion of the breakable label covering the recess may be broken upon insertion of a mechanical actuator into the recess to actuate the mechanically-actuated mechanism. This renders the identification code unreadable and prevents reuse of the cartridge.

Abstract translation: 一次性流体盒在其中具有凹部。 机械致动机构设置在凹槽内以实现流体盒的操作。 所述盒还包括在可折叠标签上的机器可识别代码，其覆盖所述凹部的至少一部分，使得在将机械致动器插入所述凹部中时，覆盖所述凹部的可破坏标签的所述部分可能被破坏， 致动机构。 这使得识别码不可读，并防止重新使用墨盒。

公开(公告)号：WO2015015176A1

公开(公告)日：2015-02-05

申请号：PCT/GB2014/052302

申请日：2014-07-28

Applicant: ATLAS GENETICS LIMITED

Inventor： KENDALL TAYLOR, Jay ,  ARLETT, Ben

IPC: B29C45/16 ,  F16K99/00 ,  B01L3/00

CPC classification number: B01L3/502738 ,  B29C45/1675 ,  B29C45/1676 ,  F16K99/0015 ,  F16K2099/0078 ,  F16K2099/008

Abstract: A fluid control device comprises a first polymer layer having a top surface, a bottom surface and a void extending through the first polymer layer and having an opening in at least the bottom surface; and a second polymer layer forming a membrane across the void in the first polymer layer. A third polymer layer having a top surface and a bottom surface may also be provided, such that the second polymer layer is disposed between the first and third polymer layers. The bottom surface of the first polymer layer and the top surface of the third polymer layer are in contacting arrangement around at least a portion of the perimeter of the second polymer layer. The fluid control device may be formed by injection-moulding a first polymer layer and subsequently injection-overmoulding a second polymer layer onto at least a portion of the first polymer layer to form a seal between the membrane and the first polymer layer.

Abstract translation: 流体控制装置包括第一聚合物层，其具有顶表面，底表面和延伸穿过第一聚合物层并且在至少底表面中具有开口的空隙; 以及在第一聚合物层中跨越空隙形成膜的第二聚合物层。 还可以提供具有顶表面和底表面的第三聚合物层，使得第二聚合物层设置在第一和第三聚合物层之间。 第一聚合物层的底表面和第三聚合物层的顶表面围绕第二聚合物层的周边的至少一部分处于接触排列。 流体控制装置可以通过注塑成型第一聚合物层并随后将第二聚合物层注射成型至第一聚合物层的至少一部分上以在膜和第一聚合物层之间形成密封来形成。