-
公开(公告)号：WO2017037629A1
公开(公告)日：2017-03-09
申请号：PCT/IB2016/055194
申请日：2016-08-31
Applicant: BASF SE , BASF (CHINA) COMPANY LIMITED
Inventor： PETZKE, Lutz , HEROLD, Andrea , FLECK, Christian , MARTY, Laurent , OEDMAN, Peter , DICKHAUT, Joachim , WEINGARTEN, Melanie , LUZHETSKY, Andriy , REBETS, Yuriy , MANDERSCHEID, Niko
CPC classification number: C12P17/181 , C12N15/52
Abstract: Provided are improved microorganisms for the biosynthesis of pamamycins. Also provided are methods for the production of pamamycins using these microorganisms.
Abstract translation: 提供了用于生物合成帕马霉素的改进的微生物。 还提供了使用这些微生物生产帕马霉素的方法。
-
公开(公告)号：WO2017109654A1
公开(公告)日：2017-06-29
申请号：PCT/IB2016/057701
申请日：2016-12-16
Applicant: BASF SE , BASF (CHINA) COMPANY LIMITED
Inventor： PETZKE, Lutz , HEROLD, Andrea , FLECK, Christian , MARTY, Laurent , OEDMAN, Peter , DICKHAUT, Joachim , WEINGARTEN, Melanie , LUZHETSKY, Andriy , REBETS, Yuriy , SCRIMA, Andrea , SCHMELZ, Stefan
IPC: C12N15/113 , C12N15/31 , C12N15/63
CPC classification number: C12N15/63
Abstract: Provided are genetic systems for inducing or repressing gene expression. The polynucleotides and polypeptides suitable to built such systems, the microorganisms comprising such systems, and the methods using such systems in combination with pamamycin to modulate gene expression are also provided.
Abstract translation: 提供用于诱导或抑制基因表达的遗传系统。 还提供了适合于构建这样的系统的多核苷酸和多肽，包含这种系统的微生物以及使用这些系统与帕马霉素组合以调节基因表达的方法。
-
3.发明申请
公开(公告)号：WO2020127140A1
公开(公告)日：2020-06-25
申请号：PCT/EP2019/085479
申请日：2019-12-17
Applicant: BASF SE
Inventor： MALISZ, Jacek , SEIBERT-LUDWIG, Daniel , OEDMAN, Peter , PUHL, Michael
Abstract: The present invention relates to a method for separating biomass from a solution comprising biomass and at least one oligosaccharide.comprising providing the solution comprising biomass and oligosaccharides.lowering the pH value of the solution below 7 by adding at least one acid to the solution comprising biomass and the at least one oligosaccharide. adding an adsorbing agent to the solution comprising biomass and oligosaccharides. and carrying out first membrane filtration so as to separate the biomass from the solution comprising the at least one oligosaccharide.
-
公开(公告)号：WO2017055518A1
公开(公告)日：2017-04-06
申请号：PCT/EP2016/073372
申请日：2016-09-29
Applicant: BASF SE
Inventor： BRAUN, Michael Guenter , DAEUWEL, Juergen , OEDMAN, Peter , KIEFER, Michael , KLEINER, Matthias , LANG, Hans-Juergen , GHISLIERI, Diego
CPC classification number: C12P13/02
Abstract: The present disclosure relates to methods for producing an amide compound from a nitrile compound using a dried biocatalyst which has been pre-treated with a buffer, wherein the dried and pre-treated biocatalyst has improved properties as compared to a dried biocatalyst which has not been pre-treated with a buffer. In particular, the present disclosure provides means and methods to enhance the NHase activity of a dried biocatalyst for use in the production of amide compounds from nitrile compounds in aqueous solutions thereby improving the bioconversion process.
Abstract translation: 本公开涉及使用已经用缓冲液进行预处理的干燥生物催化剂从腈化合物制备酰胺化合物的方法，其中干燥和预处理的生物催化剂与未被干燥的生物催化剂相比具有改善的性能 用缓冲液预处理。 特别地，本公开提供了用于增强用于在水溶液中由腈化合物生产酰胺化合物的干燥生物催化剂的NHase活性的方法和方法，从而改进了生物转化过程。
-
公开(公告)号：WO2021089584A1
公开(公告)日：2021-05-14
申请号：PCT/EP2020/080887
申请日：2020-11-04
Applicant: BASF SE
Inventor： GHISLIERI, Diego , OEDMAN, Peter , ZIMMERMANN, Tobias, Joachim
IPC: C12P13/02
Abstract: The present invention relates to a method of storing a biocatalyst, which biocatalyst is capable of converting acrylonitrile to acrylamide, comprising the steps: (a) providing an aqueous suspension comprising the biocatalyst, which is capable of converting acrylonitrile to acrylamide, which aqueous suspension is an aqueous fermentation broth; (b) sequentially in either order or simultaneously (b1) concentrating the aqueous suspension comprising the biocatalyst to a concentration of at least 3% (w/w); and (b2) reducing the temperature of the aqueous suspension comprising the biocatalyst to a temperature of below 8°C, thereby forming a concentrated aqueous suspension; and (c) maintaining the concentrated aqueous suspension of step (b) at a temperature of below 8°C. The invention also relates to a biocatalyst composition obtainable by this method and also the use of the biocatalyst composition in a process of preparing (meth-) acrylamide aqueous solution from (meth-) acrylonitrile. The invention further relates to a method for producing an aqueous (meth-) acrylamide solution comprising the aforementioned storage method and also to a method for producing polyacrylamide comprising the aforementioned storage method.
-
Patent Agency Ranking
公开(公告)号：WO2020079114A1
公开(公告)日：2020-04-23
申请号：PCT/EP2019/078147
申请日：2019-10-17
Applicant: BASF SE
Inventor： PUHL, Michael , WLOCH, Sebastian , OEDMAN, Peter , LETZEL, Anne-Catrin , SCHROEDER, Hartwig , MALISZ, Jacek , SEIBERT-LUDWIG, Daniel , KAPPERT, Emiel Jan , WONG, Chung Huan , BARROS GROSS, Michael , VIERTELHAUS, Martin
Abstract: The present invention relates to a method for obtaining crystalline 2'-fucosyllactose from a 2'-FL raw material, which contains 2'-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2'-FL, where the method comprises a)providing a solution of the 2'-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2'-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2'-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).
-
7.发明申请METHOD FOR PREPARING AN AQUEOUS ACRYLAMIDE SOLUTION HAVING A LOW ACRYLIC ACID CONCENTRATION 审中-公开制备具有低丙烯酸浓度的水性丙烯酰胺溶液的方法
公开(公告)号：WO2016050818A1
公开(公告)日：2016-04-07
申请号：PCT/EP2015/072508
申请日：2015-09-30
Applicant: BASF SE
Inventor： BRAUN, Michael , DAEUWEL, Juergen , LANG, Hans-Juergen , OEDMAN, Peter , BALDENIUS, Kai-Uwe , KLEINER, Matthias , KIEFER, Michael , FREYER, Stephan , BUDDE, Michael
IPC: C12P13/02
CPC classification number: C12P13/02 , C07C233/09 , C08F20/56 , C08L33/26 , C08L2201/54 , C09K8/588 , C12Y402/01084 , D21H17/375
Abstract: The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.
Abstract translation: 本发明涉及制备丙烯酸浓度低的丙烯酰胺水溶液的方法。 此外，本发明涉及降低丙烯酰胺水溶液的丙烯酸浓度的方法。 所述方法涉及在生物催化剂存在下将丙烯腈生物转化为丙烯酰胺，其中在生物转化期间，丙烯腈的含量维持在反应器中组合物总重量的0.3w / w％以上。 还提供了通过本发明的方法获得的丙烯酰胺水溶液。 此外，本发明涉及通过聚合水溶液的丙烯酰胺而获得的丙烯酰胺均聚物或共聚物。
-
公开(公告)号：WO2020079146A1
公开(公告)日：2020-04-23
申请号：PCT/EP2019/078209
申请日：2019-10-17
Applicant: BASF SE
Inventor： VIERTELHAUS, Martin , PUHL, Michael , WLOCH, Sebastian , OEDMAN, Peter , LETZEL, Anne-Catrin , SCHROEDER, Hartwig , MALISZ, Jacek , SEIBERT-LUDWIG, Daniel , KAPPERT, Emiel Jan , WONG, Chung Huan , BARROS GROSS, Michael
Abstract: Crystalline form II of 2'-O-fucosyl lactose having an X-ray powder diffraction pattern comprising three reflections at 2θ angles (13.65 ± 0.20)°, (16.98 ± 0.20)° and (18.32 ± 0.20)°, determined at a temperature of 25 °C with Cu-Kα 1,2 radiation having a wavelength of 0.15419 nm, said crystalline form exhibiting an α:β anomeric ratio in the range of from 4:60 to 60:40, determined by 13 C-NMR.
-
公开(公告)号：WO2020079120A1
公开(公告)日：2020-04-23
申请号：PCT/EP2019/078158
申请日：2019-10-17
Applicant: BASF SE
Inventor： GHISLIERI, Diego , OEDMAN, Peter , ZIMMERMANN, Tobias Joachim , SCHMIDT, Anna-Corina
Abstract: The present invention relates to a process for preparing ammonium (meth-) acrylate, aqueous ammonium (meth-) acrylate solutions obtainable by such process, and (meth-) acrylic acid homopolymers or copolymers obtainable by polymerizing such ammonium (meth-) acrylate. The invention furthermore relates to a modular, relocatable bioconversion unit for manufacturing aqueous ammonium (meth-) acrylate solutions.
-
公开(公告)号：WO2023041515A2
公开(公告)日：2023-03-23
申请号：PCT/EP2022/075377
申请日：2022-09-13
Applicant: BASF SE
Inventor： DAEUWEL, Juergen , BRAUN, Michael Guenter , OEDMAN, Peter , LANG, Hans-Juergen , KLEINER, Matthias , GHISLIERI, Diego
IPC: C12M1/26 , C07C231/24 , C08F220/56 , C12P13/02
Abstract: The invention provides a method for preparing an aqueous (meth)acrylamide solution, said method comprising the following steps: (a) adding the following components (i) to (iii) to a reactor to obtain a composition for bioconversion: (i) a biocatalyst capable of converting (meth) acrylonitrile to (meth) acrylamide; (ii) (meth) acrylonitrile; and (iii) water; (b) performing a bioconversion on the composition obtained in step (a) as a reaction mixture in the reactor to obtain a crude aqueous (meth) acrylamide solution; and (c) passing the crude aqueous solution through at least one filter to provide a purified aqueous (meth) acrylamide solution, wherein at least one filter of step (c) has a nominal retention rating, with at least 90% efficiency, of from 4 to 22 μm. The invention further provides an apparatus for manufacturing aqueous (meth) acrylamide solution according to the inventive method. The method comprises a bioconversion unit; a supply of (meth) acrylonitrile; a supply of biocatalyst; and a supply of water. The apparatus comprises at least one filter for purifying crude aqueous (meth) acrylamide solution, which at least one filter has a nominal retention rating, with at least 90% efficiency, of 4 to 22 μm. The invention also covers aqueous (meth) acrylamide solution obtainable by the aforesaid inventive method, polymers made therefrom, and the use of aqueous solutions of said polymers for mining applications or oil field applications.
-
-
-
-
-
-
-
-
-
Search Results
15
records
(took 0.012 seconds)
