NOVEL ENZYMES, ENZYME COMPONENTS AND USES THEREOF
    3.
    发明申请
    NOVEL ENZYMES, ENZYME COMPONENTS AND USES THEREOF 审中-公开
    新型酶,酶组分及其用途

    公开(公告)号:WO2014020533A3

    公开(公告)日:2014-02-06

    申请号:PCT/IB2013/056243

    申请日:2013-07-30

    Abstract: The invention provides nucleic acid molecules which encodes a novel fatty acid desaturase, KCS, KCR and/or LACS from Thraustochytrium aureum and Sphaeroforma arctica. The invention also provides recombinant expression vectors containing said nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., ARA, EPA and DHA and for screening for delta-4 desaturases.

    Abstract translation: 本发明提供了编码来自金黄色破囊壶菌(Thraustochytrium aureum)和Sphaeroforma arctica的新型脂肪酸去饱和酶,KCS,KCR和/或LACS的核酸分子。 本发明还提供了含有所述核酸分子的重组表达载体,导入了表达载体的宿主细胞和大规模生产长链多不饱和脂肪酸(LCPUFA)的方法,例如ARA,EPA和DHA,以及 筛选Δ-4去饱和酶。

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