公开(公告)号：WO2019005809A1

公开(公告)日：2019-01-03

申请号：PCT/US2018/039522

申请日：2018-06-26

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： KENWOOD, Shannon Smith ,  HEIGHTON, Sarah Jean ,  CLARK, Joshua ,  BACON, Dan

IPC: B01L3/00 ,  C12M1/00 ,  G01N1/40

CPC classification number: B04B5/0442 ,  B01D21/262 ,  B01D61/147 ,  B01D61/18 ,  B01D2221/10 ,  B01D2311/2676 ,  B01L3/5021 ,  B01L2200/025 ,  B01L2300/0618 ,  B01L2300/0681 ,  B01L2400/0409 ,  B04B2005/0478 ,  C12M47/02 ,  G01N1/4077 ,  G01N2001/4088

Abstract: Filtration devices and methods for collecting, filtering, and/or processing biological samples are disclosed. An example filtration device may include a funnel member having a first end region and a second end region. A flange may be coupled to the first end region. A filter support portion may be coupled to the second end region. The filter support portion may include a base, a filter membrane coupled to the base, and a securing member for securing the filter membrane to the base.

公开(公告)号：WO2019005827A1

公开(公告)日：2019-01-03

申请号：PCT/US2018/039548

申请日：2018-06-26

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： CLARK, Joshua ,  STORBECK, Gene T. ,  KENWOOD, Shannon Smith ,  BENNING, Christopher A. ,  CURRAN, Sean ,  HEIGHTON, Sarah Jean

IPC: C12N15/10 ,  B01L3/00 ,  G01N33/49 ,  B01L9/00 ,  G01N1/40 ,  C12M3/06 ,  C12M1/12

CPC classification number: G01N1/31 ,  A61B10/0283 ,  B01L3/5021 ,  B01L9/52 ,  B01L2300/0618 ,  B01L2300/0681 ,  B01L2300/12 ,  B01L2300/16 ,  B01L2400/0409 ,  C12M3/062 ,  C12M33/14 ,  C12M47/02 ,  G01N1/36 ,  G01N1/4077 ,  G01N33/5088 ,  G01N2001/2873 ,  G01N2001/4088

Abstract: A cell filtration assembly adapted to capture cells from a biological sample during centrifugation includes a filter support member including a sample well and a filter membrane that spans the sample well. In some cases, the filter support member and/or the filter membrane may be adapted to be sectioned. In some cases, a protective element may be disposed over at least a portion of the filter support member in order to protect the filter support member from tissue processing reagents during processing of the cells captured from the biological sample.

公开(公告)号：WO2019006139A1

公开(公告)日：2019-01-03

申请号：PCT/US2018/040046

申请日：2018-06-28

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： HEIGHTON, Sarah Jean ,  KENWOOD, Shannon Smith ,  CLARK, Joshua

IPC: B01D21/26 ,  B01L3/00 ,  B01D61/18 ,  G01N1/40

CPC classification number: B01L3/5021 ,  B01D21/262 ,  B01D61/18 ,  B01D63/087 ,  B01D2311/2676 ,  B01D2313/025 ,  B01D2315/02 ,  B01L2200/025 ,  B01L2300/0681 ,  B01L2300/0809 ,  B01L2300/0832 ,  B01L2400/0409 ,  B01L2400/08 ,  G01N2001/4088

Abstract: A cell filtration assembly adapted to capture cells from a biological sample during centrifugation includes a centrifugation tube, a cell collection device adapted to be secured within a tapered end of the centrifugation tube and a funnel structure adapted to direct fluid into the cell collection device. The cell collection device includes a rectilinear structure that is adapted to permit fluid to flow through the rectilinear structure and a cell capture surface that is secured relative to the rectilinear structure. The cell collection device may be sectioned in either a horizontal or vertical orientation.