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    COMPUTATION OF A BREATHING CURVE FOR MEDICAL APPLICATIONS
    1.
    发明申请
    COMPUTATION OF A BREATHING CURVE FOR MEDICAL APPLICATIONS 审中-公开

    公开(公告)号：WO2021004620A1

    公开(公告)日：2021-01-14

    申请号：PCT/EP2019/068282

    申请日：2019-07-08

    Applicant: BRAINLAB AG

    Inventor： BERLINGER, Kajetan ,  KAISER, Hagen

    IPC: A61N5/10

    Abstract: A computer-implemented medical method of determining a breathing signal (202) of a patient (100) is disclosed. The method comprises determining a motion trajectory (120) of a structure (104) associated with at least one body part of the patient (100), the motion trajectory (120) being indicative of a respiratory movement of the structure (104); acquiring surface data (50) representative of a position of a surface region (106) of the patient (100); computing an intersection of the determined motion trajectory (120) and the acquired surface data (50); and determining a breathing signal (202) of the patient (100) based on the computed intersection, wherein the breathing signal (202) is indicative of a breathing state of the patient (100).

    AUGMENTED REALITY ASSISTANCE IN MEDICAL PROCEDURE PREPARATION
    2.
    发明申请
    AUGMENTED REALITY ASSISTANCE IN MEDICAL PROCEDURE PREPARATION 审中-公开

    公开(公告)号：WO2019110135A1

    公开(公告)日：2019-06-13

    申请号：PCT/EP2017/083055

    申请日：2017-12-15

    Applicant: BRAINLAB AG

    Inventor： VILSMEIER, Stefan ,  KAISER, Hagen

    IPC: A61N5/10 ,  A61B90/00

    Abstract: The present invention relates to a method and a medical system for providing a checklist comprising a plurality of checklist-elements to be checked off in order for preparing a medical treatment and/or a medical analysis. At least the identity and the pose of the patient is checked off while an augmented reality overlay is provided over a field of view associated with a portable display device.

    PATIENT PRE-POSITIONING IN FRAMELESS CRANIAL RADIOSURGERY USING THERMAL IMAGING
    4.
    发明申请
    PATIENT PRE-POSITIONING IN FRAMELESS CRANIAL RADIOSURGERY USING THERMAL IMAGING 审中-公开
    用热成像技术进行病人无动脉手术前的定位

    公开(公告)号：WO2017190780A1

    公开(公告)日：2017-11-09

    申请号：PCT/EP2016/060048

    申请日：2016-05-04

    Applicant: BRAINLAB AG

    Inventor： BERLINGER, Kajetan ,  KAISER, Hagen

    IPC: G06T7/73

    Abstract: Disclosed is a computer-implemented medical data processing method for supporting positioning a patient for treatment by at least one of radiotherapy or radiosurgery, the method comprising executing, on at least one processor of at least one computer, steps of: a) acquiring (S1), at the at least one processor, planning image data describing a digital planning image of a reference structure; b) acquiring (S2), at the at least one processor, reference structure position data describing a predetermined relative position between the reference structure and an anatomical body part of the patient's body and describing a relative position between the reference structure and a predetermined reference position; c) acquiring (S3), at the at least one processor, thermal image data describing a digital thermal image of the reference structure; d) acquiring (S4), at the at least one processor, imaging device position data describing a relative position between the reference structure and a thermal imaging device used for taking the digital thermal image and describing a predetermined relative position between the thermal imaging device and the predetermined reference position; e) determining (S5), by the at least one processor and based on the planning image data, planning image pattern data describing an image pattern in the digital planning image assigned to the representation of the reference structure, hereinforth called planning image pattern; f) determining (S6), by the at least one processor and based on the thermal image data, thermal image pattern data describing an image pattern in the digital thermal image assigned to the representation of the reference structure, hereinforth called thermal image pattern; g) determining (S7), by the at least one processor and based on the reference structure position data and the imaging device position data and the planning image pattern data and the thermal image pattern data, positional difference data describing a difference between a relative position between the anatomical body part and the predetermined reference position at the point in time at which planning image data was generated on the one hand, and a relative position between the anatomical body part and the predetermined reference position at the point in time at which the thermal image data was generated on the other hand.

    Abstract translation: 公开了一种计算机实现的医疗数据处理方法，用于支持通过放射疗法或放射手术中的至少一个来放置患者进行治疗，所述方法包括：在至少一个计算机的至少一个处理器上， 步骤：a）在所述至少一个处理器处获取（S1）描述参考结构的数字计划图像的计划图像数据; b）在所述至少一个处理器处获取（S2）参考结构位置数据，所述参考结构位置数据描述所述参考结构与所述患者身体的解剖身体部分之间的预定相对位置，并且描述所述参考结构与预定参考位置之间的相对位置 ; c）在所述至少一个处理器处获取（S3）描述所述参考结构的数字热图像的热图像数据; d）在所述至少一个处理器处获取（S4）成像装置位置数据，所述成像装置位置数据描述所述参考结构与用于获取所述数字热图像的热成像装置之间的相对位置，并且描述所述热成像装置与所述热成像装置之间的预定相对位置 预定参考位置; e）由所述至少一个处理器并且基于所述计划图像数据来确定（S5）计划图像图案数据，所述计划图像图案数据描述在所述数字计划图像中分配给所述参考结构的表示的图像图案，在此称为计划图像图案; f）由所述至少一个处理器并且基于所述热图像数据确定（S6）热图像图案数据，所述热图像图案数据描述被分配给所述参考结构的表示的数字热图像中的图像图案，在此称为热图像图案; g）由所述至少一个处理器并基于所述参考结构位置数据和所述成像装置位置数据以及所述计划图像图案数据和所述热图像图案数据确定（S7）位置差异数据，所述位置差异数据描述相对位置 一方面在生成计划图像数据的时间点处的解剖身体部位与预定参考位置之间的相对位置以及在解热身体部位与预定参考位置之间的相对位置 图像数据是在另一方面产生的。

    SORTING THE SEQUENTIAL ARRANGEMENT OF RADIATION TREATMENT BEAMS REGARDING WELL-DISTRIBUTED UNOBSTRUCTED LINES OF SIGHT
    5.
    发明申请
    SORTING THE SEQUENTIAL ARRANGEMENT OF RADIATION TREATMENT BEAMS REGARDING WELL-DISTRIBUTED UNOBSTRUCTED LINES OF SIGHT 审中-公开
    根据井眼分布式无缝线路分选辐射处理梁的顺序布置

    公开(公告)号：WO2017137527A1

    公开(公告)日：2017-08-17

    申请号：PCT/EP2017/052940

    申请日：2017-02-10

    Applicant: BRAINLAB AG

    Inventor： BERLINGER, Kajetan ,  KAISER, Hagen

    IPC: A61N5/10 ,  G06F19/00

    CPC classification number: A61N5/1049 ,  A61N5/1064 ,  A61N5/1069 ,  A61N2005/1059 ,  G06F19/3481 ,  G06T1/0007 ,  G06T7/77 ,  G06T7/80 ,  G06T7/97 ,  G06T2207/10116

    Abstract: Disclosed is a computer-implemented medical data processing method for determining a positional pattern of an irradiation unit for irradiating a patient with treatment radiation, the irradiation unit being part of an irradiation treatment device having an imaging device for generating a medical image of the patient, the method comprising executing, on at least one processor of at least one computer, steps of: a) acquiring (S1), at the at least one processor, irradiation unit position data describing irradiation unit positions of the irradiation unit for which the imaging device has a free viewing direction onto the position of the patient which is a free line of sight from the imaging device to the position of the patient; b) determining (S2), by the at least one processor and based on the irradiation unit position data, position orders data describing all possible orders of the irradiation unit positions for which the imaging device has a free viewing direction onto the position of the patient; c) determining (S3), by the at least one processor and based on the irradiation unit position data and the position orders data and per order described by the position orders data, intersection angle data describing a statistical quantity of the intersection angles between free viewing directions of the imaging unit for irradiation unit positions which are immediately subsequent in the order described by the position orders data; d) determining (S4), by the at least one processor and based on the intersection angle data and the position orders data, optimal order data describing an order of the irradiation unit positions for which the statistical value is optimal.

    Abstract translation: 公开了一种计算机实现的医学数据处理方法，用于确定用于用治疗放射线照射患者的照射单元的位置图案，所述照射单元是具有成像装置的照射治疗装置的一部分，所述成像装置用于 生成患者的医疗图像，所述方法包括在至少一个计算机的至少一个处理器上执行以下步骤：a）在所述至少一个处理器处获取描述照射单元位置的照射单元位置数据（S1） 所述成像装置具有自由观察方向的所述照射单元到所述患者的位置，所述患者的位置是从所述成像装置到所述患者的位置的自由视线; b）由至少一个处理器并基于照射单元位置数据确定（S2）位置顺序数据，所述位置顺序数据描述成像设备具有自由观察方向的照射单元位置的所有可能顺序到患者的位置上 ; c）由所述至少一个处理器并且基于所述照射单元位置数据和所述位置顺序数据以及由所述位置顺序数据描述的每个顺序来确定（S3）所述交叉角度数据，所述交叉角度数据描述自由观看之间的所述交叉角度的统计量 根据位置顺序数据所描述的顺序紧随其后的照射单元位置的成像单元的方向; d）由至少一个处理器并且基于交叉角数据和位置顺序数据确定（S4）描述统计值是最优的照射单元位置的顺序的最佳顺序数据。

    MEDICAL IMAGE FUSION WITH REDUCED SEARCH SPACE
    6.
    发明申请
    MEDICAL IMAGE FUSION WITH REDUCED SEARCH SPACE 审中-公开
    医学图像融合与减少搜索空间

    公开(公告)号：WO2017001441A1

    公开(公告)日：2017-01-05

    申请号：PCT/EP2016/065076

    申请日：2016-06-29

    Applicant: BRAINLAB AG

    Inventor： BERLINGER, Kajetan ,  KAISER, Hagen

    IPC: A61B6/00 ,  A61N5/10 ,  G06T7/00 ,  A61B6/04

    CPC classification number: G06T7/74 ,  A61B6/0407 ,  A61B6/4085 ,  A61B6/5229 ,  A61B6/5235 ,  A61N5/103 ,  A61N5/1039 ,  A61N5/1049 ,  A61N2005/1062 ,  G06T7/33 ,  G06T19/20 ,  G06T2207/10004 ,  G06T2207/10081 ,  G06T2207/10116 ,  G06T2207/20092 ,  G06T2207/20221 ,  G06T2207/30004 ,  G06T2207/30168 ,  G06T2210/41 ,  G06T2219/2004 ,  G06T2219/2016

    Abstract: A computer implemented method for performing fusion of 3D image data, which represent at least a part of a patient's body, with two 2D images of the patient's body with a known spatial relation between the viewing directions of the 2D images, comprising the steps of: -acquiring the 3D image data, -acquiring the two 2D images, -calculating two virtual images from the 3D image data, the two virtual images corresponding to the two 2D images, -classifying the two 2D images into a primary and a secondary image, -determining a primary alignment between the primary image and the corresponding virtual image such that they match, -calculating a spatial axis relative to the viewing directions of the two 2D images from the primary alignment and a predetermined point which is imaged in the virtual image which corresponds to the primary image, wherein the spatial axis is a line in space on which the predetermined point lies, and -performing fusion of the 3D image data with the two 2D images based on the calculated spatial axis in order to obtain a virtual position of the 3D image data in space.

    Abstract translation: 一种计算机实现的方法，用于执行表示所述患者身体的至少一部分的3D图像数据与所述2D图像的观看方向之间的已知空间关系的所述患者身体的两个2D图像的融合，所述方法包括以下步骤： - 获取3D图像数据， - 获取两个2D图像， - 从3D图像数据计算两个虚拟图像，对应于两个2D图像的两个虚拟图像， - 将两个2D图像分类为主图像和次图像， - 确定主图像和相应虚拟图像之间的主要对准，使得它们匹配，相对于来自主对准的两个2D图像的观看方向和在虚像中被成像的预定点计算空间轴， 对应于主图像，其中空间轴是预定点所在的空间中的线，并且执行3D图像数据与基于o的两个2D图像的融合 n计算的空间轴，以便获得空间中的3D图像数据的虚拟位置。

    STABILITY ESTIMATION OF A POINT SET REGISTRATION
    8.
    发明申请
    STABILITY ESTIMATION OF A POINT SET REGISTRATION 审中-公开

    公开(公告)号：WO2021180333A1

    公开(公告)日：2021-09-16

    申请号：PCT/EP2020/056809

    申请日：2020-03-13

    Applicant: BRAINLAB AG

    Inventor： IVANOVSKA, Ivana ,  KAISER, Hagen ,  APONTE, Pablo ,  VEIGEL, Jochen

    IPC: G16H40/60 ,  G16H50/50

    Abstract: The present invention relates to a method encompassing acquiring data as to the geometric structure/topology of a predefined surface section as well as to an additional physical property assigned to the surface section, determining variability of the geometric structure/topology as well as of the additional physical property over the surface section, and determining from these at variabilities an expected stability of co-registering datasets describing the predefined surface section. The present invention further relates to a corresponding computer program and a corresponding system for carrying out this method.

    TRIGGERING OF X-RAY-IMAGES BASED ON SURFACE MEASUREMENTS
    9.
    发明申请
    TRIGGERING OF X-RAY-IMAGES BASED ON SURFACE MEASUREMENTS 审中-公开

    公开(公告)号：WO2021028022A1

    公开(公告)日：2021-02-18

    申请号：PCT/EP2019/071660

    申请日：2019-08-13

    Applicant: BRAINLAB AG

    Inventor： BERLINGER, Kajetan ,  KAISER, Hagen ,  STEAD, Michael

    IPC: A61B6/08 ,  A61B6/00 ,  A61N5/10

    Abstract: The present invention relates to a computer-implemented medical method for monitoring a spatial position of a patient's body part (8), wherein at least one optimum spatial direction for a line of sight of a check x-ray-image is determined, that qualifies for quantifying a deviation of the spatial position of the patient's body part (8) from a target spatial position for the patient's body part (8). The present invention further relates to a corresponding computer program and a corresponding medical system (1).

    BEAM PATH BASED PATIENT POSITIONING AND MONITORING
    10.
    发明申请
    BEAM PATH BASED PATIENT POSITIONING AND MONITORING 审中-公开

    公开(公告)号：WO2020020623A1

    公开(公告)日：2020-01-30

    申请号：PCT/EP2019/068274

    申请日：2019-07-08

    Applicant: BRAINLAB AG

    Inventor： KAISER, Hagen ,  STEAD, Michael

    IPC: A61N5/10

    Abstract: A computer-implemented medical method of positioning a patient for a radiation treatment and/or of monitoring a position of a patient during a radiation treatment is provided. The method comprises providing surface data acquired by means of a 3D surface scanner (12) of a surface (102) of at least a body part (100) of the patient, which body part (100) is to be irradiated in a radiation treatment. The surface data are calibrated with respect to a relative position of the 3D surface scanner (12) and an isocenter position of a radiation treatment apparatus (22). A beam path (110) and/or frustum (110) of a radiation beam is determined based on planning data for the radiation treatment and intersected with at least a part of the surface (102) of the patient represented by the surface data. Further, at least a first portion (106) of the patient's surface (102) located inside the beam path (110) and/or a second portion (108) of the patient's surface (102) located outside the beam path (110) is calculated.

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