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11 条记录 (耗时 0.015 秒)

    NON-INVASIVE PH-DEPENDENT IMAGING USING QUANTITATIVE CHEMICAL EXCHANGE SATURATION TRANSFER (QCEST)
    2.
    发明申请
    NON-INVASIVE PH-DEPENDENT IMAGING USING QUANTITATIVE CHEMICAL EXCHANGE SATURATION TRANSFER (QCEST) 审中-公开
    利用定量化学交换饱和转移（QCEST）进行非侵入性PH相关成像

    公开(公告)号：WO2017214439A1

    公开(公告)日：2017-12-14

    申请号：PCT/US2017/036617

    申请日：2017-06-08

    申请人： CEDARS-SINAI MEDICAL CENTER

    发明人： GAZIT, Dan ,  LI, Debiao ,  PELLED, Gadi ,  GAZIT, Zulma ,  ZHOU, Zhengwei

    IPC分类号： A61B5/00 ,  A61B5/05 ,  A61B5/055

    摘要： In various embodiments, the invention teaches systems and methods for magnetic resonance imaging. In some embodiments, the invention teaches systems and methods for determining the source of pain in intervertebral discs by measuring one or more physiological biomarkers associated with disc pain and/or disc degeneration.

    摘要翻译： 在各种实施例中，本发明教导了用于磁共振成像的系统和方法。 在一些实施方案中，本发明教导了通过测量与椎间盘疼痛和/或椎间盘退变相关的一种或多种生理生物标志物来确定椎间盘中疼痛源的系统和方法。

    SYSTEMS AND METHODS FOR CALCIUM-FREE COMPUTED TOMOGRAPHY ANGIOGRAPHY
    3.
    发明申请
    SYSTEMS AND METHODS FOR CALCIUM-FREE COMPUTED TOMOGRAPHY ANGIOGRAPHY 审中-公开

    公开(公告)号：WO2020172188A1

    公开(公告)日：2020-08-27

    申请号：PCT/US2020/018678

    申请日：2020-02-18

    申请人： CEDARS-SINAI MEDICAL CENTER

    发明人： XIE, Yibin ,  LI, Debiao ,  DEY, Damini ,  CHEN, Yuhua

    IPC分类号： G06T5/00 ,  G06T11/00 ,  A61B6/03

    摘要： A method of analyzing computed tomography (CT) images comprises receiving an initial CT image of an object, identifying calcium-free regions and a calcified region in the initial CT image of the object, generating a calcium-free image patch, and applying the calcium-free image patch to the initial CT image patch to produce a final CT image. The initial CT image shows a calcium deposit and a target structure in the object. The calcified region in the initial CT image shows the calcium deposit in the object obscuring a portion of the target structure. The calcium-free regions show the remaining portions of the target structure. The calcium-free image patch corresponds to the calcified region in the initial CT image. The final CT image shows the calcium-free image patch and the calcium-free region from the initial CT image. The calcium-free image patch is generated and applied using a convolutional neural network.

    UNIFIED COIL (UNIC) SYSTEMS AND METHOD FOR NEXT GENERATION MAGNETIC RESONANCE COILS
    4.
    发明申请
    UNIFIED COIL (UNIC) SYSTEMS AND METHOD FOR NEXT GENERATION MAGNETIC RESONANCE COILS 审中-公开
    用于下一代磁共振线圈的统一线圈（UNIC）系统和方法

    公开(公告)号：WO2017079487A1

    公开(公告)日：2017-05-11

    申请号：PCT/US2016/060403

    申请日：2016-11-03

    申请人： CEDARS-SINAI MEDICAL CENTER

    发明人： HAN, Hui ,  LI, Debiao

    IPC分类号： G01R33/24 ,  G01R33/3875 ,  A61B5/055

    CPC分类号： G01R33/3875 ,  A61B5/0042 ,  A61B5/0044 ,  A61B5/055 ,  G01R33/341 ,  G01R33/3415

    摘要： A unified coil assembly for magnetic resonance imaging is disclosed. The coil assembly includes an RF coil element and a shim coil array with a shim coil element. The shim coil element is physically separated or partially separated from the RF coil element. The shim coil element includes a DC current loop having a DC power supply connection to allow DC current to generate a local B0 magnetic field. The unified coil array assembly is configured to simultaneously provide an RF mode for at least one of transmit or receive and a direct current mode to generate a local B0 magnetic field for B0 shimming. Larger number of shim coils relative to the RF coil element provides superior shimming performance. The mutual inductance between the shim coil element and the RF coil element is minimized by proposed geometrical decoupling methods in order to minimize the RF interaction between the two.

    摘要翻译： 公开了一种用于磁共振成像的统一线圈组件。 线圈组件包括RF线圈元件和具有匀场线圈元件的匀场线圈阵列。 匀场线圈元件与RF线圈元件物理分离或部分分离。 匀场线圈元件包括具有DC电源连接的DC电流回路，以允许DC电流产生局部B 0磁场。 统一线圈阵列组件被配置为同时提供用于发射或接收中的至少一个的RF模式以及用于生成用于B0匀场的局部B0磁场的直流电模式。 相对于RF线圈元件的更多数量的匀场线圈提供优异的匀场性能。 匀场线圈元件和RF线圈元件之间的互感通过所提出的几何去耦方法来最小化，以便使两者之间的RF相互作用最小化。

    SYSTEMS AND METHODS FOR MR MULTITASKING-BASED DYNAMIC IMAGING FOR CEREBROVASCULAR EVALUATION
    5.
    发明申请
    SYSTEMS AND METHODS FOR MR MULTITASKING-BASED DYNAMIC IMAGING FOR CEREBROVASCULAR EVALUATION 审中-公开

    公开(公告)号：WO2021257742A1

    公开(公告)日：2021-12-23

    申请号：PCT/US2021/037695

    申请日：2021-06-16

    申请人： CEDARS-SINAI MEDICAL CENTER

    发明人： FAN, Zhaoyang ,  CHRISTODOULOU, Anthony ,  LI, Debiao ,  HU, Zhehao

    IPC分类号： G01R33/563 ,  G01R33/465 ,  G01R33/56 ,  A61B5/055

    摘要： A method for performing magnetic resonance imaging on a subject comprises: injecting a contrast agent into a region of interest of the subject; applying a pulse sequence to the region of interest; collecting auxiliary data for the region of interest, the auxiliary data being related to one or more time-varying parameters of the subject within the region of interest; determining a temporal factor Φ from the auxiliary data; collecting imaging data for the region of interest, the imaging data being related to one or more spatially-varying parameters of the subject within the region of interest; determining a spatial factor Ur from the imaging data; modeling a multi-dimensional image sequence as I=UrΦ; and deriving at least a first metric and a second metric from the multi-dimensional image sequence I, the first metric and the second metric being associated with distinct perfusion-based imaging techniques.

    DEVICES AND METHODS FOR PARAHYDROGEN INDUCED POLARIZATION
    7.
    发明申请
    DEVICES AND METHODS FOR PARAHYDROGEN INDUCED POLARIZATION 审中-公开
    PARAHYDROGEN诱导极化的装置和方法

    公开(公告)号：WO2014039907A1

    公开(公告)日：2014-03-13

    申请号：PCT/US2013/058625

    申请日：2013-09-06

    申请人： CEDARS-SINAI MEDICAL CENTER

    发明人： WAGNER, Shawn ,  AGRAZ, Jose ,  LI, Debiao

    IPC分类号： G01R33/28 ,  G01N24/08

    CPC分类号： B01J19/088 ,  A61K49/06 ,  B01J2219/0805 ,  C07C69/67 ,  G01R33/282 ,  G01R33/5601

    摘要： The present invention teaches devices and methods for hyperpolarization by parahydrogen induced polarization. The invention teaches several significant improvements over previous designs, including a heating block, an enhanced solenoid component, and pinch valves and tubing that provide a sterile environment for the sample. All of these advancements can be accomplished while keeping costs to produce the device relatively low.

    摘要翻译： 本发明教导了通过仲氢诱导的极化进行超极化的装置和方法。 本发明教导了与先前设计相比的几个显着改进，包括加热块，增强电磁元件以及为样品提供无菌环境的夹管阀和管。 所有这些进步都可以在保持相对低的生产设备的成本的同时完成。

    PREDICTION OF PANCREATIC DUCTAL ADENOCARCINOMA USING COMPUTED TOMOGRAPHY IMAGES OF PANCREAS
    9.
    发明申请
    PREDICTION OF PANCREATIC DUCTAL ADENOCARCINOMA USING COMPUTED TOMOGRAPHY IMAGES OF PANCREAS 审中-公开

    公开(公告)号：WO2021146199A1

    公开(公告)日：2021-07-22

    申请号：PCT/US2021/013093

    申请日：2021-01-12

    申请人： CEDARS-SINAI MEDICAL CENTER ,  WU, Bechien ,  GADDAM, Srinivas

    发明人： LI, Debiao ,  PANDOL, Stephen Jacob ,  QURESHI, Touseef Ahmad

    IPC分类号： A61K39/395 ,  G01N33/53

    摘要： According to some implementations of the present disclosure, a system for identifying individuals at risk for PDAC includes a CT scanner, a memory, and a control system. The CT scanner is configured to generate CT image data associated with a pancreas of a patient. The memory stores machine-readable instructions. The control system includes one or more processors configured to execute the machine-readable instructions. The CT image data associated with the pancreas of the patient is received. The received CT image data is processed to output a set of CT image features. The set of CT image features is received as an input to a machine learning PDAC prediction algorithm. An indication of whether the patient is at high risk for PDAC is determined as an output of the machine learning PDAC prediction algorithm.

    SYSTEMS AND METHODS OF DEEP LEARNING FOR LARGE-SCALE DYNAMIC MAGNETIC RESONANCE IMAGE RECONSTRUCTION
    10.
    发明申请
    SYSTEMS AND METHODS OF DEEP LEARNING FOR LARGE-SCALE DYNAMIC MAGNETIC RESONANCE IMAGE RECONSTRUCTION 审中-公开

    公开(公告)号：WO2021050765A1

    公开(公告)日：2021-03-18

    申请号：PCT/US2020/050247

    申请日：2020-09-10

    申请人： CEDARS-SINAI MEDICAL CENTER

    发明人： CHRISTODOULOU, Anthony ,  LI, Debiao ,  CHEN, Yuhua

    IPC分类号： G01R33/56 ,  G01R33/465

    摘要： A method for performing magnetic resonance imaging on a subject comprises obtaining undersampled imaging data, extracting one or more temporal basis functions from the imaging data, extracting one or more preliminary spatial weighting functions from the imaging data, inputting the one or more preliminary spatial weighting functions into a neural network to produce one or more final spatial weighting functions, and multiplying the one or more final spatial weighting functions by the one or more temporal basis functions to generate an image sequence. Each of the temporal basis functions corresponds to at least one time-varying dimension of the subject. Each of the preliminary spatial weighting functions corresponds to a spatially-varying dimension of the subject. Each of the final spatial weighting functions is an artifact-free estimation of the one of the one or more preliminary spatial weighting functions.