公开(公告)号：WO2019209623A1

公开(公告)日：2019-10-31

申请号：PCT/US2019/028117

申请日：2019-04-18

Applicant: DANISCO US INC

Inventor： BECKER, Nathaniel T. ,  JOHNSON, Mariliz Ortiz ,  KALOGRIDES, Amanda Jane ,  PEPSIN, Michael J. ,  REICHMAN, Michael

IPC: A23K20/189 ,  A23K20/26 ,  A23K40/10 ,  A23K40/30 ,  A23L29/00 ,  C12N9/96 ,  C12N9/14 ,  A23K10/14

Abstract: The present compositions and methods relate to thermostabilization of phytase with inorganic phosphate and increasing the recovery of phytase during the production of heat-treated food or animal feed pellets that contain phytase. The phosphate is introduced to the solid composition. The phosphate and phytase are in functional proximity and at a molar ratio of at least 50:1. Multi-layered granules are taught.

公开(公告)号：WO2015042334A2

公开(公告)日：2015-03-26

申请号：PCT/US2014/056435

申请日：2014-09-19

Applicant: DANISCO US INC. ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： BECKER, Nathaniel T. ,  GILES, Durham K. ,  SCHER, Herbert B. ,  BAKER, Helen C. ,  MOSLEMY, Peyman

IPC: B01J13/04

CPC classification number: B01J13/043 ,  A23K20/147 ,  A23K20/189 ,  A23K40/10 ,  A61K9/5089 ,  B01J13/12 ,  C11D17/0039

Abstract: The present teachings provide a method for coating particles containing thermally sensitive biologically active materials encapsulated by uniform thin protective moisture barrier coatings, and processes for applying such coatings efficiently, at ambient temperatures and with minimal agglomeration. The coating formulations can comprise dispersants, adhesion promoters, polymers, and plasticizers dissolved or dispersed in a non-flammable, low boiling point solvent such as methylene chloride that is delivered with an aerosol process to target particles. The present teachings also include the resulting particles.

Abstract translation: 本教导提供了一种用于涂覆包含由均匀的薄防护防潮涂层包封的热敏生物活性材料的颗粒的方法，以及用于在环境温度下且在最小附聚的情况下有效地施加这种涂层的方法。 涂料配方可以包含溶解或分散在不易燃的低沸点溶剂如二氯甲烷中的分散剂，粘合促进剂，聚合物和增塑剂，所述溶剂通过气溶胶方法递送至目标颗粒。 本教导还包括所得到的颗粒。

公开(公告)号：WO2009035700A2

公开(公告)日：2009-03-19

申请号：PCT/US2008/010737

申请日：2008-09-12

Applicant: DANISCO US INC., GENENCOR DIVISION ,  BECKER, Nathaniel T. ,  BRAUN, Ryszard ,  CHRISTENSEN, Robert I. ,  EKBOM, Stefan ,  FONG, Robin ,  SCHULER, Alexandra

Inventor： BECKER, Nathaniel T. ,  BRAUN, Ryszard ,  CHRISTENSEN, Robert I. ,  EKBOM, Stefan ,  FONG, Robin ,  SCHULER, Alexandra

IPC: B01D61/14 ,  B01D63/10 ,  B01D65/02 ,  B01D65/08

CPC classification number: B01D65/00 ,  B01D61/14 ,  B01D63/10 ,  B01D65/02 ,  B01D65/08 ,  B01D2311/06 ,  B01D2313/19 ,  B01D2321/02 ,  B01D2321/04 ,  B01D2321/10 ,  B01D2321/12 ,  B01D2321/20 ,  B01D2321/2008 ,  B01D2321/2083 ,  B01D2311/14 ,  B01D2311/165

Abstract: Filtration processes and systems are provided for the separation of a filterable fluid stream by a filtration membrane module with uniform transmembrane pressure and flux along the membrane and internal control of membrane fouling via intermittent periodic reduction of the pressure differential between the permeate and retentate sides of the membrane and/or backwashing cycles during separation, recovery, and/or purification of proteins, peptides, nucleic acids, biologically produced polymers and other compounds or materials from aqueous fluids.

Abstract translation: 提供了过滤方法和系统，用于通过过滤膜组件分离可过滤流体流，该过滤膜组件具有沿着膜的均匀的跨膜压力和通量以及膜污染的内部控制，通过间歇性周期性减少渗透物和渗余物侧之间的压力差 在从水性流体分离，回收和/或纯化蛋白质，肽，核酸，生物制备的聚合物和其它化合物或其它化合物的过程中，膜和/或反冲洗循环。

公开(公告)号：WO2022076535A1

公开(公告)日：2022-04-14

申请号：PCT/US2021/053741

申请日：2021-10-06

Applicant: DANISCO US INC.

Inventor： BECKER, Nathaniel T. ,  MAURER, Samuel A. ,  SINDELAR, Jared ,  GOMMEREN, Henricus Jacobus Cornelis ,  BALA, Ashwin

IPC: A01N25/12 ,  A01N25/26 ,  A01N59/26 ,  A01N63/20 ,  A01N63/22 ,  A01N63/25 ,  A01N63/27 ,  A01N63/28 ,  A01N63/30 ,  A01N63/32 ,  A01N63/34 ,  A01N63/38 ,  A01N63/50 ,  A61K9/16 ,  A23K10/16

Abstract: Described are compositions and methods relating to layered granules comprising a core surrounded by a coating layer containing bioactive agents distributed within a protectant matrix, wherein the protectant matrix includes at least one polyhydroxy compound and at least one phosphate compound. The core and the protectant matrix are water soluble and fast-dissolving.

公开(公告)号：WO2019125683A1

公开(公告)日：2019-06-27

申请号：PCT/US2018/061820

申请日：2018-11-19

Applicant: DANISCO US INC

Inventor： BECKER, Nathaniel T. ,  PEYMAN, Moslemy

IPC: C11D3/386 ,  C11D11/00 ,  C11D7/20 ,  C11D3/12 ,  A23K20/105 ,  A23K20/189 ,  A23K20/28 ,  A23K20/22 ,  A23K40/10 ,  C12N9/98 ,  C12N9/16 ,  A01N25/12 ,  A23P10/22 ,  A23L29/00 ,  C05F11/00 ,  C05D9/00

CPC classification number: C11D3/38672 ,  A01N25/12 ,  A23K20/105 ,  A23K20/189 ,  A23K20/22 ,  A23K20/28 ,  A23K40/10 ,  A23K40/30 ,  A23L29/015 ,  A23L29/06 ,  A23P10/22 ,  C05D9/00 ,  C05F11/00 ,  C05F11/08 ,  C11D3/1246 ,  C11D3/128 ,  C11D7/20 ,  C11D11/0082 ,  C12N9/16 ,  C12N9/98 ,  C12Y301/03

Abstract: Described are compositions and methods relating to enzyme-containing, hot-melt-prepared granules produced from a starting material that contains an amount of water sufficient to denature the enzyme under hot-melt processing conditions. The resulting granules are particularly useful in consumer and industrial products, such as detergent, animal feed, food, personal care and agricultural compositions.

公开(公告)号：WO2019089898A1

公开(公告)日：2019-05-09

申请号：PCT/US2018/058665

申请日：2018-11-01

Applicant: DANISCO US INC

Inventor： BECKER, Nathaniel T. ,  MCAULIFFE, Joseph C. ,  MOSLEMY, Peyman ,  TAN, Jared Enwei ,  WHITE, Luther

IPC: A61K9/16 ,  A61K38/43

CPC classification number: A61K9/1694 ,  A61K9/1611 ,  A61K9/1617 ,  A61K9/1623 ,  C12N9/96

Abstract: The present disclosure is generally related to freezing point depressed solid matrix (FPDSM) systems, methods thereof and formulations thereof, wherein the FPDSM system stabilizes solid enzyme compositions thereof. In certain embodiments, the disclosure is related to methods for inhibiting the degradation of solid enzyme compositions formulated with one or more FPDSM systems of the disclosure.

公开(公告)号：WO2016201069A1

公开(公告)日：2016-12-15

申请号：PCT/US2016/036638

申请日：2016-06-09

Applicant: DANISCO US INC

Inventor： DOAN, Huy ,  GEBERT, Mark ,  BECKER, Nathaniel T. ,  DALE, Douglas A.

IPC: C11D3/386 ,  C11D17/00

CPC classification number: C11D17/0013 ,  C11D3/38663

Abstract: Described are compositions and methods relating to low density enzyme-containing particles for inclusion in cleaning and other low-water compositions. The particles remain in suspension without settling, and release active enzyme upon dilution of the low-water compositions with water.

Abstract translation: 描述了与包含在清洁和其它低水组合物中的低密度含酶颗粒有关的组合物和方法。 颗粒保持悬浮而不沉降，并在用水稀释低水组合物时释放活性酶。

公开(公告)号：WO2020086821A1

公开(公告)日：2020-04-30

申请号：PCT/US2019/057823

申请日：2019-10-24

Applicant: DANISCO US INC

Inventor： BECKER, Nathaniel T. ,  BEDEKAR, Amruta ,  HERMANSEN, Regina Arakel ,  HOFFMANN, Katherine ,  IVERSON, Amanda Kathleen ,  MAURER, Samuel A. ,  VIRAG, Aleksandra

IPC: A01N25/08 ,  A01N25/12 ,  A01N63/20 ,  A01N63/22 ,  A01N63/30 ,  A01N63/38

Abstract: Described are compositions and methods relating to formulations and process conditions for stabilizing microorganisms for extended storage under ambient conditions without refrigeration, humidity control, or special packaging.

公开(公告)号：WO2019156670A1

公开(公告)日：2019-08-15

申请号：PCT/US2018/017367

申请日：2018-02-08

Applicant: DANISCO US INC.

Inventor： MOSLEMY, Peyman ,  BECKER, Nathaniel T. ,  BARNARD, Luke

IPC: A23K20/158 ,  C11D3/386 ,  A23K20/189 ,  A23K40/10

CPC classification number: A23K20/158 ,  A23K20/189 ,  A23K40/10 ,  C11D3/38672

Abstract: Described are compositions and methods relating to thermally-resistant wax matrix particles for enzyme encapsulation. The particles are well-suited for animal feed applications, particularly those involving steam pelleting.

公开(公告)号：WO2018183662A1

公开(公告)日：2018-10-04

申请号：PCT/US2018/025120

申请日：2018-03-29

Applicant: DANISCO US INC

Inventor： KALOGRIDES, Amanda Jane ,  ANGELES, Christopher James ,  BECKER, Nathaniel T. ,  COLLIER, Katherine D. ,  HUANG, Victoria ,  MOSLEMY, Peyman ,  WHITE, Luther ,  CHEN, Jeffrey

IPC: C11D3/386 ,  C11D3/39 ,  C11D3/395

Abstract: Described are compositions and methods relating to delayed release enzyme formulations for bleach-containing detergents, and methods of use, thereof. The formulations are designed to promote the rapid release of a bleaching agent into a wash liquor and the delayed release of a protease, to reduce the undesirable effect that high concentrations of bleach have on protease activity. The compositions and methods have applications in, e.g. , laundry and dishwashing.