公开(公告)号：WO2008082966A2

公开(公告)日：2008-07-10

申请号：PCT/US2007/088028

申请日：2007-12-20

Applicant: MEDRAD, INC.

Inventor： TATE, Leon, J. ,  SHIGENO, James ,  RYGG, Steven, C. ,  NEFF, Jared E. ,  GRIFFITH, Scott ,  BISEGNA, Joseph, E. ,  ILGENFRITZ, Edward ,  MILLER, Paul, J. ,  YANKE, Scott H.

IPC: A61M36/08

CPC classification number: A61M5/172 ,  A61K51/00 ,  A61M5/007 ,  A61M5/14 ,  A61M5/16822 ,  A61M5/3146 ,  A61M2005/1402 ,  G06F19/3468 ,  G16H20/17

Abstract: A fluid path set for a fluid delivery system includes a tube coil that is designed to optimally position one or more volumes of a pharmaceutical within an ionization chamber to optimally measure and prepare a pharmaceutical dose for administration to a patient. The tube coil may be maintained in a desired dimensional geometry by means of a core structure around which the tube coil is positioned. Novel developments in radiopharmaceutical administration methods and systems include, but are not limited to, the configuration and layout of a fluid path set for use in a fluid delivery system, arrangements for piercing and drawing fluid from a pharmaceutical container (such as a vial), arrangements for optimizing the positioning of a tube coil within an ionization chamber, a handling system for transporting vial shields that maintain an operator's hand and fingers at a safe distance from a pharmaceutical vial, a method for calibrating a radiopharmaceutical delivery system in which the difference between the expected and measured activities of two radioisotopes are used to calculate an estimated error in the measured activity of a third radioisotope and a vial access system that ensures an optimal draw of fluid from a radiopharmaceutical container.

Abstract translation: 设置用于流体输送系统的流体路径包括管线圈，其设计成在电离室内优化地定位药物的一个或多个体积，以最佳地测量并制备用于给予患者的药物剂量。 管线圈可以通过围绕管线圈定位的芯结构保持在期望的尺寸几何形状。 放射性药物管理方法和系统的新发展包括但不限于用于流体输送系统的流体路径组的配置和布置，用于从药物容器（例如小瓶）刺穿和抽取流体的布置， 用于优化电离室内的管线圈的定位的布置，用于运输维护操作者的手和手指与药物瓶的安全距离的小瓶护罩的处理系统，用于校准放射性药物递送系统的方法，其中， 使用两个放射性同位素的预期和测量的活动来计算第三放射性同位素和小瓶进入系统的测量活动的估计误差，其确保从放射性药物容器中最佳地吸取流体。

公开(公告)号：WO2013043868A1

公开(公告)日：2013-03-28

申请号：PCT/US2012/056328

申请日：2012-09-20

Applicant: MEDRAD, INC.

Inventor： CAPONE, Christopher, D. ,  SEMAN, Richard, A. ,  HAURY, John, A. ,  PREM, Edward, K. ,  BISEGNA, Joseph, E. ,  HELLER, Ronald ,  WILLIAMS, Glen, P. ,  MATOR, Joseph, C. ,  BAZALA, Jason, L.

IPC: A61M5/142 ,  A61M5/145 ,  F04B15/00 ,  F04B19/04 ,  F16K11/02

CPC classification number: A61M5/16881 ,  A61M5/007 ,  A61M5/1408 ,  A61M5/1422 ,  A61M5/1452 ,  A61M39/223 ,  A61M2039/229 ,  A61M2205/50 ,  A61M2205/6063 ,  A61M2207/00 ,  B05B11/3015 ,  B23P15/001 ,  F04B49/06 ,  F04B49/065 ,  F04B49/22 ,  F04B53/16 ,  F16K11/07 ,  G05D7/0635 ,  Y10T29/49229 ,  Y10T29/49236 ,  Y10T29/49412 ,  Y10T29/5191 ,  Y10T137/86879

Abstract: A fluid pump device is operable by a drive and actuating system. The fluid pump device includes a pump manifold, a plurality of pump cylinders, a plunger reciprocally operable in each of the pump cylinders, and at least one inlet selector valve. The pump cylinders may extend proximally from the pump manifold and are in selective fluid communication with the pump manifold via, for example, respective inlet and outlet check valves. The plungers are reciprocally operable within the pump cylinders and are independently and reciprocally operable by respective piston linear actuators provided in the drive and actuating system. The inlet selector valve is used to establish selective fluid communication between one or more fluid source containers and the pump manifold to control fluid flow into the pump manifold. The inlet selector valve may be located laterally outboard of the pump cylinders and extend generally parallel to the pump cylinders.

Abstract translation: 流体泵装置可通过驱动和致动系统操作。 流体泵装置包括泵歧管，多个泵缸，可在每个泵缸中往复运动的柱塞和至少一个入口选择阀。 泵筒可以从泵歧管向近侧延伸，并且通过例如相应的入口和出口止回阀与泵歧管选择性地流体连通。 柱塞在泵缸内可往复操作，并且通过设置在驱动和致动系统中的相应的活塞线性致动器独立地和可往复地操作。 入口选择阀用于在一个或多个流体源容器和泵歧管之间建立选择性流体连通，以控制流入泵歧管的流体流动。 入口选择阀可以位于泵缸的横向外侧并且大致平行于泵缸延伸。

公开(公告)号：WO2002066100A2

公开(公告)日：2002-08-29

申请号：PCT/US2002/004827

申请日：2002-02-20

Applicant: MEDRAD, INC.

Inventor： COWAN, Kevin, P. ,  HITCHINS, Mark, W. ,  BISEGNA, Joseph, E. ,  MCFALL, Frank, B. ,  TROMBLEY, Frederick, W., III ,  GRUBIC, Herbert, M. ,  REILLY, David, M. ,  UBER, Arthur, E., III ,  SCIULLI, Francis, J. ,  SCHRIVER, Ralph, H.

IPC: A61M3/00

CPC classification number: A61M39/1011 ,  A61M2039/1033 ,  A61M2039/1044

Abstract: A syringe for use in a medical injection procedure in connection with connectors having a tapered fitting includes a syringe tip having a cooperating tapered fitting including a passage therein in fluid communication with an interior of the syringe. The syringe also includes a first connecting member having a radially inward threaded portion on an inner surface thereof adapted to connect to a first type of connector including a tapered fitting having at least one radially outward extending flange adapted to connect to the radially inward threaded portion of the first connecting member. In that regard, the first connecting member allows connection of the syringe to, for example, a standard luer fitting connector. The syringe further includes a second connecting member having at least one attachment member such as a radially outward extending flange adapted to connect to a second type of connector which includes a tapered fitting and a cooperating attachment member to engage the at least one attachment member of the second connecting member. The second connecting member allows connection of the syringe to improved tapered fitting connectors described herein.

Abstract translation: 用于与具有锥形配件的连接器相关的医疗注射程序的注射器包括具有配合的锥形配件的注射器末端，其包括与注射器的内部流体连通的通道。 注射器还包括第一连接构件，其内表面上具有径向向内的螺纹部分，其适于连接到第一类型的连接器，该第一连接器包括具有至少一个径向向外延伸的凸缘的锥形配件，该凸缘适于连接到径向向内螺纹部分 第一连接构件。 在这方面，第一连接构件允许注射器连接到例如标准鲁尔接头连接器。 注射器还包括第二连接构件，其具有至少一个附接构件，例如径向向外延伸的凸缘，其适于连接到第二类型的连接器，该第二类型的连接器包括锥形配件和配合的附接构件，以与所述至少一个连接构件 第二连接构件。 第二连接构件允许注射器连接到本文所述的改进的锥形配合连接器。