公开(公告)号：WO2003023371A1

公开(公告)日：2003-03-20

申请号：PCT/US2002/028846

申请日：2002-09-10

Applicant: QUIDEL CORPORATION

Inventor： JEROME, Jeremy ,  DAQUIPA, Mark ,  JACONO, Bruce ,  BOEHRINGER, Hans ,  LAMBOTTE, Paul ,  LAWRENCE, Paul, J.

IPC: G01N21/00

CPC classification number: G01N21/8483 ,  B01L3/5023 ,  G01N33/54386 ,  G01N33/558 ,  Y10S435/805 ,  Y10S435/823 ,  Y10S436/807 ,  Y10S436/81 ,  Y10S436/823 ,  Y10T436/25125

Abstract: A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support (14) or member bearing a mark (46)thereon, and a matrix (18) or member containing a capture zone (40). In operation, an observation area (38) in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (-) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (-) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user.

Abstract translation: 测试装置和方法，用于确定流体样品中一种或多种分析物的存在或不存在，该测试装置包括其上带有标记（46）的支撑件（14）或部件，以及 基质（18）或包含捕获区（40）的构件。 在操作中，测试装置中的观察区域（38）变得透明，从而允许使用者观察位于观察区域下方的支撑物上存在的标记。 通常，底层支持上的标记配置为减号（ - ）。 在样品中不存在分析物的情况下，测试装置呈现负（ - ）信号的结果。 然而，在样品中存在分析物的情况下，该标记与观察区域上的垂直测试线协同工作，以呈现正面结果作为用户可见的正（+）信号。

公开(公告)号：WO2021231781A1

公开(公告)日：2021-11-18

申请号：PCT/US2021/032321

申请日：2021-05-13

Applicant: QUIDEL CORPORATION

Inventor： KEHLE, Johannes ,  JACONO, Bruce ,  KROLL, Werner ,  SUR, Kunal ,  PARPIA, Zaheet ,  ELIOPOULOS, Andrew ,  MOROVICH, Matthew ,  MCDANIELS-DAVIDSON, Jesse ,  BJARNASON, Jon ,  WITKOWICKI, Jesse ,  LINHOFF, Todd ,  PACK, Todd Denison

IPC: B01L3/00 ,  G01N35/04 ,  B01L2200/021 ,  B01L2200/0605 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0609 ,  B01L2300/0663 ,  B01L2300/0672 ,  B01L2300/069 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2300/14 ,  B01L2400/043 ,  B01L2400/0436 ,  B01L2400/0487 ,  B01L2400/0655 ,  B01L2400/0683 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/5029 ,  B01L3/527 ,  B01L3/561 ,  C12N15/1013 ,  C12Q1/6806 ,  C12Q1/6848 ,  G01N21/55 ,  G01N35/0098

Abstract: A system for analysis of a sample to aid in diagnosis and/or detection of the presence or absence, and/or the identity of, an analyte in the sample is provided. A cartridge with reagents to isolate nucleic acid from a sample inserted in the cartridge and to amplify the isolated nucleic acid, and an instrument that interacts with the cartridge, together provide a self-contained sample to answer system for detection, identification, differentiation and/or quantification of a target nucleic acid in a sample.