公开(公告)号：WO2022032094A1

公开(公告)日：2022-02-10

申请号：PCT/US2021/044940

申请日：2021-08-06

Applicant: OVERTURE LIFE, INC.

Inventor： MUNNE, Santiago ,  HORCAJADAS ALMANSA, José Antonio ,  MATTHYS, Lionel ,  SALES FIDALGO, Joana Alexandra ,  CARASA RUIZ, Pablo ,  MARTIN VILLALBA, Tamara ,  CANCIO VILLALONGA, David ,  GARCIA ALONSO, Daniel ,  DOSDA MUNUERA, Cristina ,  ALVAREZ ARGUELLES, Sara

IPC: A61B17/425 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/0681 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2300/14 ,  B01L2400/049 ,  B01L2400/06 ,  B01L3/502715

Abstract: Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.

公开(公告)号：WO2021231781A1

公开(公告)日：2021-11-18

申请号：PCT/US2021/032321

申请日：2021-05-13

Applicant: QUIDEL CORPORATION

Inventor： KEHLE, Johannes ,  JACONO, Bruce ,  KROLL, Werner ,  SUR, Kunal ,  PARPIA, Zaheet ,  ELIOPOULOS, Andrew ,  MOROVICH, Matthew ,  MCDANIELS-DAVIDSON, Jesse ,  BJARNASON, Jon ,  WITKOWICKI, Jesse ,  LINHOFF, Todd ,  PACK, Todd Denison

IPC: B01L3/00 ,  G01N35/04 ,  B01L2200/021 ,  B01L2200/0605 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0609 ,  B01L2300/0663 ,  B01L2300/0672 ,  B01L2300/069 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2300/14 ,  B01L2400/043 ,  B01L2400/0436 ,  B01L2400/0487 ,  B01L2400/0655 ,  B01L2400/0683 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/502761 ,  B01L3/5029 ,  B01L3/527 ,  B01L3/561 ,  C12N15/1013 ,  C12Q1/6806 ,  C12Q1/6848 ,  G01N21/55 ,  G01N35/0098

Abstract: A system for analysis of a sample to aid in diagnosis and/or detection of the presence or absence, and/or the identity of, an analyte in the sample is provided. A cartridge with reagents to isolate nucleic acid from a sample inserted in the cartridge and to amplify the isolated nucleic acid, and an instrument that interacts with the cartridge, together provide a self-contained sample to answer system for detection, identification, differentiation and/or quantification of a target nucleic acid in a sample.