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公开(公告)号：WO2014108682A3
公开(公告)日：2014-07-17
申请号：PCT/GB2014/050048
申请日：2014-01-09
Applicant: SMITH & NEPHEW PLC
Inventor： DAGGER, Anthony , FRY, Nicholas, Charlton , HAMMOND, Victoria, Jody , HICKS, John, Kenneth , LAURIE, Alexander, Speirs , LECOMTE, Helene, Anne , MOSS, Rhianna , MUMBY, Ella, Lynne
Abstract: This application discloses a wound dressing comprising an absorbent layer and a moisture indicator which indicates wound exudate loading within the dressing, wherein the visibility of the moisture indicator changes as a result of a physical transformation of a first material within the dressing.
Abstract translation: 本申请公开了一种伤口敷料，其包含吸收层和指示敷料内伤口渗出物负载量的湿度指示剂，其中湿度指示剂的可见度由于第一材料的物理变化而改变 在敷料内。
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公开(公告)号：WO2017121871A1
公开(公告)日：2017-07-20
申请号：PCT/EP2017/050704
申请日：2017-01-13
Applicant: SMITH & NEPHEW PLC
Inventor： HICKS, John, Kenneth , HOSKINS, Richard , RIMMER, Stephen , MCCULLOCH, Dorothy
CPC classification number: A61F13/00055 , A61F13/8405 , G01N31/221
Abstract: Device comprising polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having 5 immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising: hydrophilic monomer; and indicator monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; 10 characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10 and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said 15 ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.
Abstract translation: 包含聚氨酯材料的装置，所述聚氨酯材料用于指示位置处的pH，优选作为微生物存在的指示，所述装置包含聚氨酯网络，所述聚氨酯网络具有固定在其中的一种或多种亲水共聚物，所述或每种所述共聚物包含：亲水单体 ; 和指示剂单体，其提供响应于所述亲水性单体和/或共聚物的亲水状态变化的指示; 其特征在于所述共聚物或每种共聚物还包含一个或多个可离子化基团或部分或可聚合单体，所述可离子化基团或部分或可聚合单体具有一个或多个5至10范围内的特征性pKa值并且对所述基因座处pH为5至10 pH10并且亲水共聚物的亲水状态取决于所述可电离基团，部分或单体的电离; 包含该材料和其制备方法的试剂盒和装置; 并用于检测或检测微生物或pH值。
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公开(公告)号：WO2016005288A1
公开(公告)日：2016-01-14
申请号：PCT/EP2015/065234
申请日：2015-07-03
Applicant: SMITH & NEPHEW PLC
Inventor： HICKS, John, Kenneth , RIMMER, Stephen , MCCULLOCH, Dorothy , HOSKINS, Richard
CPC classification number: G01N21/78 , A61L15/26 , A61L15/425 , A61L15/58 , C08F220/56 , C08G18/10 , C08G18/42 , C08G18/4277 , C08G18/44 , C08G18/48 , C08G18/4833 , C08G18/4854 , C08G18/73 , C08G18/758 , C08G18/7614 , C08G18/7621 , C08G18/7671 , C08G18/7678 , C08G2101/00 , C08G2101/0091 , C08G2270/00 , C08K3/00 , C08K2003/2227 , C08L33/26 , C08L75/02 , C08L75/04 , C08L2205/04 , C12Q1/18 , G01N21/77 , G01N21/80 , G01N33/56911 , G01N33/56938 , G01N2333/21 , G01N2333/31 , G01N2800/26 , C08G18/302
Abstract: A polyurethane material for the detection or sensing of species or stimulus comprising a polyurethane network comprising immobilised therein, or modified by the immobilisation therein of, a hydrophilic polymer comprising a ligand or moiety for the detection or sensing of species or stimulus and an indicator for indicating detection or sensing wherein species or stimulus is selected from chemical or biological species or stimulus; the material for medical, dental, hygiene, point of use sterilisation, sanitation, personal care, biosurveillance or packaging use, the use thereof preferably for detecting and/or sensing or binding bacteria, or for detecting or sensing pH or for detection or scanning with use of a reader; a Kit and a device comprising the same; and a process for the preparation thereof.
Abstract translation: 用于检测或感测物种或刺激物的聚氨酯材料，其包含聚氨酯网络，其包含固定在其中或通过其中固定而修饰的包含用于检测或感测物种或刺激的配体或部分的亲水性聚合物，以及用于指示 检测或感测，其中物种或刺激物选自化学或生物物种或刺激物; 用于医疗，牙科，卫生，使用点灭菌，卫生，个人护理，生物监视或包装使用的材料，其优点用于检测和/或感染或结合细菌，或用于检测或感测pH或用于检测或检测pH 使用读者; 套件和包括该套件的装置; 及其制备方法。
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公开(公告)号：WO2019020829A1
公开(公告)日：2019-01-31
申请号：PCT/EP2018/070528
申请日：2018-07-30
Applicant: SMITH & NEPHEW PLC
Inventor： HAMMOND, Victoria, Jody , HICKS, John, Kenneth , MUMBY, Ella, Lynn , NOBLE, Stephanie, Jane
CPC classification number: A61F13/00017 , A61F13/00038 , A61F13/00042 , A61F13/00068 , A61F13/00987 , A61F13/00995 , A61L15/425 , B29C44/5636 , B29C2035/0855 , B29K2033/04 , B29K2075/00 , B29K2105/04 , B29K2105/045 , B29K2995/0068 , B29K2995/0092 , B29L2031/753 , C08J9/36 , C08J2205/04 , C08J2205/05 , C08J2375/04
Abstract: A method of manufacturing an absorbent layer for use in a wound product and an absorbent layer is provided. The method includes placing a layer of foam between two opposed pressing surfaces. The foam is compressed foam between the two pressing surfaces to reduce the thickness of the foam and the foam is dielectrically heated the foam during compression between the pressing surfaces.
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公开(公告)号：WO2014013348A3
公开(公告)日：2014-01-23
申请号：PCT/IB2013/002485
申请日：2013-05-21
Applicant: SMITH & NEPHEW PLC
Abstract: A wound dressing (100) for use in the application of negative pressure to a wound, comprising a support member (102) and a cover member (106) positionable over the wound in use. The support member can have a first support element having a first portion (116a) aligned with a first axis and a body portion (114) coupled with and extending away from the first portion, and a second support element having a first portion (116b) aligned with the first axis and a body portion (114) coupled with and extending away from the first portion of the second support element. At least the body portion of each of the first support element and the second support element can be independently rotatable about the first axis. The support member can support at least a middle portion of the cover member above a surface of the wound so as to define a space between the wound cover and the wound.
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Patent Agency Ranking6.发明申请
公开(公告)号：WO2013175309A1
公开(公告)日：2013-11-28
申请号：PCT/IB2013/001555
申请日：2013-05-23
Applicant: SMITH & NEPHEW PLC
Inventor： DAGGER, Anthony, C. , FRY, Nicholas, Charlton , HICKS, John, Kenneth , HUDDLESTON, Elizabeth, Mary , PHILLIPS, Marcus, Damian , SAXBY, Carl , DUNN, Raymond M.
IPC: A61F13/00
CPC classification number: A61F13/00021 , A61F13/00068 , A61M1/0088
Abstract: The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue.
Abstract translation: 本发明涉及一种负压伤口闭合系统及其使用方法。 本发明的优选实施方案通过优先收缩促进伤口的闭合以提供组织的移动。
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公开(公告)号：WO2015110411A1
公开(公告)日：2015-07-30
申请号：PCT/EP2015/050964
申请日：2015-01-20
Applicant: SMITH & NEPHEW PLC
Inventor： SAXBY, Carl , HICKS, John, Kenneth , HAMMOND, Victoria, Jody , CUVELIER, Sebastien, Antoine, Yves , WICKS, Benjamin
CPC classification number: A61B5/445 , A61B5/0013 , A61B5/0077 , A61B5/1032 , A61B5/14539 , A61B5/4842 , A61B5/4848 , A61B2562/0295 , A61B2576/00 , A61F2013/00948 , A61F2013/427 , G01N21/80 , G01N33/84 , G01N2800/52
Abstract: Systems, devices, and methods are provided for monitoring wound status and progression by measuring pH levels indicated by pH-sensitive wound dressings. In some implementations, a wound is monitored by capturing an image of the pH-sensitive wound dressing and processing the captured image to determine the color of a pH indicator included on the wound dressing. The color of the indicator is determined in terms of RGB values from the image, and a pH value for the wound dressing is calculated from the dressing RGB values. The calculated pH value is then relayed to a user to be used as an indicator of wound status or health.
Abstract translation: 提供系统，装置和方法，通过测量由pH敏感的伤口敷料指示的pH水平来监测伤口状态和进展。 在一些实施方案中，通过捕获pH敏感伤口敷料的图像并处理所捕获的图像来确定伤口敷料上包含的pH指示剂的颜色来监测伤口。 根据来自图像的RGB值确定指示器的颜色，并根据修整RGB值计算伤口敷料的pH值。 然后计算的pH值被传递给用户以用作伤口状态或健康的指标。
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公开(公告)号：WO2015052225A1
公开(公告)日：2015-04-16
申请号：PCT/EP2014/071520
申请日：2014-10-08
Applicant: SMITH & NEPHEW PLC
Inventor： HICKS, John, Kenneth , HAMMOND, Victoria, Jody
IPC: G01N31/22
CPC classification number: G01N31/221 , A61B5/14539 , A61F2013/427 , G01N21/80 , G01N27/4165
Abstract: Disclosed herein are devices and methods for determining the pH of fluid. Example devices include a device comprising a surface configured to contact the fluid and a pH indicator covalently bound thereto, wherein the pH indicator has a first colour prior to contact with the fluid and changes colour as a function of the pH of the fluid.
Abstract translation: 本文公开了用于确定流体pH的装置和方法。 示例性装置包括包括被配置为接触流体的表面和共价结合到其上的pH指示剂的装置，其中pH指示剂在与流体接触之前具有第一颜色并且根据流体的pH改变颜色。
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公开(公告)号：WO2013175310A2
公开(公告)日：2013-11-28
申请号：PCT/IB2013/001562
申请日：2013-05-21
Applicant: SMITH & NEPHEW PLC
Inventor： DODD, James, Roderick , HAMMOND, Victoria, Jody , HARTWELL, Edward, Yerbury , HICKS, John, Kenneth , HUDDLESTON, Elizabeth, Mary , SAXBY, Carl
IPC: A61B17/06
CPC classification number: A61F13/00034 , A61B17/06166 , A61B2017/06176 , A61B2090/3966 , A61F13/00029 , A61F13/00051 , A61F13/00055 , A61F13/00068 , A61F13/148 , A61F13/44 , A61F2013/00174 , A61F2013/00357 , A61F2013/00412 , A61F2013/00536 , A61F2013/0054 , A61M1/0025 , A61M1/0027 , A61M1/0088 , A61M2205/3344
Abstract: Some arrangements disclosed herein relate to devices and methods for treating a wound, comprising applying negative pressure to the wound through a cover applied over a wound, monitoring the internal pressure in the wound, and controlling the closure of the wound by controlling the amount that a wound packing material positioned under the cover collapses within the wound based on the monitored internal pressure. The wound packing material collapse can be controlled to ensure that the monitored internal pressure does not exceed a threshold value. Additionally, some embodiments or arrangements disclosed herein relate to a visualization element to visualize a location of a wound surface. The visualization element can comprise a radiopaque member that is configured to be positioned on or adjacent to a surface of an open wound.
Abstract translation: 本文公开的一些布置涉及用于治疗伤口的装置和方法，包括通过施加在伤口上的覆盖物对伤口施加负压，监测伤口中的内部压力，以及通过控制伤口的量来控制伤口闭合 基于所监测的内部压力，位于盖下方的伤口包装材料在伤口内塌陷。 可以控制伤口包装材料塌陷，以确保所监测的内部压力不超过阈值。 此外，本文公开的一些实施例或布置涉及可视化元件以可视化伤口表面的位置。 可视化元件可以包括不透射线的构件，其被配置为定位在开口伤口的表面上或邻近开口伤口的表面。
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公开(公告)号：WO2017121873A1
公开(公告)日：2017-07-20
申请号：PCT/EP2017/050711
申请日：2017-01-13
Applicant: SMITH & NEPHEW PLC
Inventor： HICKS, John, Kenneth , HOSKINS, Richard , RIMMER, Stephen , MCCULLOCH, Dorothy
IPC: A61B5/145 , A61F13/00 , A61L15/22 , A61L15/56 , C08G18/48 , C08G18/73 , C08G18/76 , C08G18/10 , C08G18/24 , C08G18/28 , C08L75/04
CPC classification number: C08L75/04 , A61B5/14539 , A61F13/00063 , A61L15/225 , A61L15/56 , C08G18/10 , C08G18/244 , C08G18/246 , C08G18/283 , C08G18/4837 , C08G18/73 , C08G18/7664 , C08L2205/04 , C08L33/26 , C08L33/02 , C08G18/3206
Abstract: Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising: hydrophilic monomer; and indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10 and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.
Abstract translation: 用于指示某一地点的pH，优选地作为微生物存在的指示的聚氨酯材料，其包含其中固定有一种或多种亲水性共聚物的聚氨酯网络，所述或每种所述共聚物包含：亲水性单体; 并指示单体，其响应所述亲水单体和/或共聚物的亲水状态的变化提供指示; 其特征在于所述共聚物或每种共聚物还包含一个或多个可离子化基团或部分或可聚合单体，所述可离子化基团或部分或可聚合单体具有一个或多个5至10范围内的特征性pKa值并且响应pH5至pH范围内所述基因座处的pH 并且亲水性共聚物的亲水状态取决于所述可电离基团，部分或单体的电离; 包含该材料和其制备方法的试剂盒和装置; 并用于检测或检测微生物或pH值。
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