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    DYNAMIC TARGET MASKER IN RADIATION TREATMENT OF MULTIPLE TARGETS
    2.
    发明申请
    DYNAMIC TARGET MASKER IN RADIATION TREATMENT OF MULTIPLE TARGETS 审中-公开

    公开(公告)号：WO2018104291A1

    公开(公告)日：2018-06-14

    申请号：PCT/EP2017/081492

    申请日：2017-12-05

    Applicant: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG

    Inventor： OLLILA, Santtu ,  VAINIO, Mikko ,  PELTOLA, Jarkko ,  NORD, Janne

    IPC: A61N5/10

    Abstract: A method for determining MLC leaf sequences for radiation treatment includes obtaining BEV projections of a first target volume and a second target volume along one or more treatment paths of a radiation treatment plan, analyzing the BEV projections to determine one or more contiguous ranges of spatial points where there exists an interstitial region between the first target volume and the second target volume in the direction of MLC leaf motion, and determining a first set of MLC leaf sequences such that an aperture formed by the MLC in a first portion of the one or more contiguous ranges of spatial points exposes radiation to the first target volume but not the second target volume, and an aperture formed by the MLC in a second portion of the one or more contiguous ranges of spatial points exposes radiation to the second target volume but not the first target volume.

    CREATING TREATMENT FIELD USING INITIAL FIELD AND PATIENT SPECIFIC GEOMETRY AND ACHIEVABLE DOSE
    3.
    发明申请
    CREATING TREATMENT FIELD USING INITIAL FIELD AND PATIENT SPECIFIC GEOMETRY AND ACHIEVABLE DOSE 审中-公开
    使用初始野外和患者特异性几何和可实现的剂量创建治疗领域

    公开(公告)号：WO2018054873A3

    公开(公告)日：2018-03-29

    申请号：PCT/EP2017/073568

    申请日：2017-09-19

    Applicant: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG

    Inventor： OLLILA, Santtu ,  VAINIO, Mikko ,  PELTOLA, Jarkko ,  NORD, Janne ,  KUUSELA, Esa

    IPC: A61N5/10

    Abstract: Methods and systems are provided for developing radiation therapy treatment plans. A treatment template with radiation fields can be chosen for a patient based on a tumor location. Static radiation field positions can be adjusted for the patient, while arc radiation fields may remain the same. Static radiation field positions can be adjusted using dose gradient, historical patient data, and other techniques.

    Abstract translation: 为开发放射疗法治疗计划提供了方法和系统。 基于肿瘤位置可以为患者选择具有辐射场的治疗模板。 可以为患者调整静态辐射场位置，而电弧辐射场可以保持不变。 可以使用剂量梯度，历史患者数据和其他技术来调整静态辐射场位置。

    GENERATING TIME-EFFICIENT TREATMENT FIELD TRAJECTORIES FOR EXTERNAL-BEAM RADIATION TREATMENTS
    5.
    发明申请
    GENERATING TIME-EFFICIENT TREATMENT FIELD TRAJECTORIES FOR EXTERNAL-BEAM RADIATION TREATMENTS 审中-公开
    生成用于外照射治疗的时效治疗野外运动

    公开(公告)号：WO2018050883A1

    公开(公告)日：2018-03-22

    申请号：PCT/EP2017/073422

    申请日：2017-09-18

    Applicant: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG

    Inventor： OLLILA, Santtu ,  VAINIO, Mikko ,  PELTOLA, Jarkko ,  NORD, Janne ,  KUUSELA, Esa ,  KAUPPINEN, Juha ,  PETAJA, Viljo ,  RUSANEN, Marko

    IPC: A61N5/10

    Abstract: In a radiation treatment plan that includes a plurality of treatment fields of multiple treatment modalities, such as IMRT modality and dynamic treatment path modality (e.g., VMAT and conformal arc therapy), an optimized spatial point sequence may be determined that optimizes the total treatment time, which includes both the beam-on time (i.e., during the delivery of radiation dose) and the beam-off time (i.e., during transitions between consecutive treatment fields). The result is a time-ordered field trajectory that intermixes and interleaves different treatment fields, in one embodiment, a dynamic treatment path may be cut into a plurality of sections, and one or more IMRT fields may be inserted between the plurality of sections.

    Abstract translation: 在包括诸如IMRT模态和动态治疗路径模态（例如，VMAT和共形电弧治疗）的多个治疗模态的多个治疗场的放射治疗计划中，优化的空间点序列可以 被确定为优化总治疗时间，其包括射束开启时间（即，在辐射剂量的递送期间）和射束关闭时间（即，在连续治疗区域之间的过渡期间）。 结果是混合并交织不同处理区域的时间有序的场轨迹。在一个实施例中，动态处理路径可以被切割成多个区段，并且可以在多个区段之间插入一个或多个IMRT字段。 / p>

    CONTROLLING AND SHAPING THE DOSE DISTRIBUTION OUTSIDE TREATMENT TARGETS IN EXTERNAL-BEAM RADIATION TREATMENTS
    6.
    发明申请
    CONTROLLING AND SHAPING THE DOSE DISTRIBUTION OUTSIDE TREATMENT TARGETS IN EXTERNAL-BEAM RADIATION TREATMENTS 审中-公开
    控制和塑造外部辐射治疗中的剂量分布外部治疗目标

    公开(公告)号：WO2018054907A1

    公开(公告)日：2018-03-29

    申请号：PCT/EP2017/073652

    申请日：2017-09-19

    Applicant: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG

    Inventor： OLLILA, Santtu ,  VAINIO, Mikko ,  PELTOLA, Jarkko ,  NORD, Janne

    IPC: A61N5/10

    Abstract: Streamlined and partially automated methods of setting normal tissue objectives in radiation treatment planning are provided. These methods may be applied to multiple-target cases as well as single-target cases. The methods can impose one or more target-specific dose falloff constraints around each target, taking into account geometric characteristics of each target such as target volume and shape. In some embodiments, methods can also take into account a planner's preferences for target dose homogeneity. In some embodiments, methods can generate additional dose falloff constraints in locations between two targets where dose bridging is likely to occur.

    Abstract translation: 提供了在放射治疗计划中设定正常组织目标的简化和部分自动化的方法。 这些方法可能适用于多目标案例以及单目标案例。 考虑到每个目标的几何特征，诸如目标体积和形状，该方法可以在每个目标周围施加一个或多个目标特定剂量衰减约束。 在一些实施例中，方法还可以考虑计划者对目标剂量均匀性的偏好。 在一些实施方案中，方法可以在可能发生剂量桥接的两个目标之间的位置产生额外的剂量衰减约束。

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