公开(公告)号：WO2012145431A3

公开(公告)日：2013-01-17

申请号：PCT/US2012034124

申请日：2012-04-18

Applicant: MICROVENTION INC ,  CONSTANT MICHAEL ,  GARRETSON JOSH ,  CRUISE GREGORY M

Inventor： CONSTANT MICHAEL ,  GARRETSON JOSH ,  CRUISE GREGORY M

IPC: A61M29/04 ,  A61B17/22 ,  A61F2/06 ,  A61L27/14 ,  A61L27/52 ,  A61L27/58

CPC classification number: A61L31/048 ,  A61B17/1214 ,  A61B17/1215 ,  A61B90/39 ,  A61B2090/3966 ,  A61L31/06 ,  A61L31/14 ,  A61L31/145 ,  A61L31/18 ,  A61L2430/36 ,  A61M25/0097 ,  A61M25/0122 ,  A61M2025/0042 ,  C08F222/385 ,  C08L71/02

Abstract: Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations of the vasculature with radiopaque hydrogel filaments with delayed controlled rates of expansion. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed.

Abstract translation: 本文描述的是用延迟受控扩张速率封闭具有不透射线水凝胶细丝的脉管系统的结构和畸形的装置，组合物，系统和相关方法。 进一步描述的是用于植入动物中的装置，其包括双功能低分子量烯属不饱和可成形大分子单体; 烯属不饱和单体; 和不透射线的元件，其中所述装置不包含支撑构件。 还公开了形成这种装置的方法。

公开(公告)号：WO2012145431A2

公开(公告)日：2012-10-26

申请号：PCT/US2012/034124

申请日：2012-04-18

Applicant: MICROVENTION, INC. ,  CONSTANT, Michael ,  GARRETSON, Josh ,  CRUISE, Gregory, M.

Inventor： CONSTANT, Michael ,  GARRETSON, Josh ,  CRUISE, Gregory, M.

IPC: A61M29/04 ,  A61L27/58 ,  A61L27/52 ,  A61L27/14 ,  A61F2/06 ,  A61B17/22

CPC classification number: A61L31/048 ,  A61B17/1214 ,  A61B17/1215 ,  A61B90/39 ,  A61B2090/3966 ,  A61L31/06 ,  A61L31/14 ,  A61L31/145 ,  A61L31/18 ,  A61L2430/36 ,  A61M25/0097 ,  A61M25/0122 ,  A61M2025/0042 ,  C08F222/385 ,  C08L71/02

Abstract: Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations of the vasculature with radiopaque hydrogel filaments with delayed controlled rates of expansion. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed.

Abstract translation: 本文描述的是具有延迟受控扩张速率的不透射线水凝胶细丝堵塞脉管系统的结构和畸形的装置，组合物，系统和相关方法。 进一步描述了用于植入动物中的装置，其包括双功能低分子量烯属不饱和可成形大分子单体; 烯属不饱和单体; 和不透射线的元件，其中所述装置不包含支撑构件。 还公开了形成这种装置的方法。

公开(公告)号：WO2007017876A3

公开(公告)日：2008-11-06

申请号：PCT/IL2006000925

申请日：2006-08-10

Applicant: TECHNION RES & DEV FOUNDATION ,  SHOHAM MOSHE ,  HASSIDOV NOAM ,  GLOZMAN DANIEL

Inventor： SHOHAM MOSHE ,  HASSIDOV NOAM ,  GLOZMAN DANIEL

IPC: A61M37/00

CPC classification number: A61M25/0155 ,  A61B1/00156 ,  A61B1/31 ,  A61M25/0116 ,  A61M25/0122

Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, the end ones of which expand at least radially when inflated. Connecting passages provide fluid communication between each pair of adjacent chambers. A fluid source is attached to one of the end chambers. The connecting passages are such that the fluid inflates the chambers in a sequence, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The same sequence occurs when the chambers deflate, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The fluid source can either be a fluid supply tube, extending to a supply outside the lumen, or it can be built-in and carried by the device. The device can crawl either along the lumen wall or on an inserted guide wire.

Abstract translation: 一种用于通过内腔移动的自推进装置，包括一组串联布置的可充气腔室，其最终端部在充气时至少径向膨胀。 连接通道在每对相邻的室之间提供流体连通。 流体源连接到一个端室。 连接通道使得流体以最接近源的室开始并且以与源最远的室结束的顺序对室进行充气。 当腔室从最靠近源极的腔室开始，并且离离子源最远的腔室终止时，发生相同的顺序。 流体源可以是流体供应管，延伸到管腔外的供应源，或者可以由装置内置并承载。 该装置可沿着管腔壁或插入的导丝线爬行。

公开(公告)号：WO2008099389A2

公开(公告)日：2008-08-21

申请号：PCT/IL2008/000180

申请日：2008-02-12

Applicant: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. ,  HASSIDOV, Noam ,  GLOZMAN, Daniel ,  SHOHAM, Moshe

Inventor： HASSIDOV, Noam ,  GLOZMAN, Daniel ,  SHOHAM, Moshe

IPC: G03F3/08

CPC classification number: F01B19/00 ,  A61B17/12045 ,  A61B17/12136 ,  A61B2017/00557 ,  A61B2017/12127 ,  A61B2017/22055 ,  A61B2090/306 ,  A61B2090/3614 ,  A61M25/0122

Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, and incorporating a number of novel aspects. To enable easy insertion and use, the rigidity of the device is increased by means of rigid inserts in the balloons, or by use of stiff springs between segments. The working channel can be attached to the distal chamber of the device, such that it is pulled from the leading end of the device during inflation, rather than being pulled from the trailing end of the device during deflation. Lumen wall inspection or treatment facilities are enabled by means of a camera or treatment arm mounted between two distally positioned balloons, the device is able to provide observation capabilities to the lumen wall, yet without becoming excessively dirty by exposure to the front end of the device, as in prior art camera units.

Abstract translation: 一种用于通过内腔运动的自推进装置，包括一组串联布置的可充气室，并且结合了许多新颖的方面。 为了易于插入和使用，通过气球中的刚性插入件或通过在段之间使用刚性弹簧来增加装置的刚性。 工作通道可以附接到装置的远端腔室，从而在充气期间从工具的前端被拉出，而不是在放气期间从设备的后端拉出。 腔壁检查或治疗设施通过安装在两个远端定位的气球之间的相机或治疗臂来实现，该装置能够向管腔壁提供观察能力，而不会因暴露于装置的前端而变得过分脏 ，如在现有技术的相机单元中。

公开(公告)号：WO2006012421A2

公开(公告)日：2006-02-02

申请号：PCT/US2005/025888

申请日：2005-07-20

Applicant: ST. JUDE MEDICAL, DAIG DIVISION, INC. ,  KNUDSON, John C. ,  FORSBERG, Andrew T.

Inventor： KNUDSON, John C. ,  FORSBERG, Andrew T.

CPC classification number: A61M25/0122 ,  A61B18/1492 ,  A61B2017/003 ,  A61B2017/00539 ,  A61B2018/1465 ,  A61M25/0136 ,  A61M25/0155

Abstract: A hydraulically assisted actuator in a handle (e.g., 6) connects with a catheter having a deflectable distal ablation tip (e.g., 64). The hydraulic actuator translates small mechanical movement by a clinician into large travel movements of connected steering cables (e.g., 38, 40) and increased tension in the ablation tip for greater deflection. The hydraulic system further dampens the return of the ablation tip from a deflected position to an equilibrium position. The hydraulic actuation system is also incorporated into a set of foot pedals (e.g., 106, 108).

Abstract translation: 手柄（例如6）中的液压辅助致动器与具有可偏转远端消融尖端（例如64）的导管连接。 液压执行器将临床医生的小机械运动转换为连接的转向电缆（例如，38,40）的大的行进运动，并且在消融尖端中增加张力以实现更大的偏转。 液压系统进一步抑制消融尖端从偏转位置返回到平衡位置。 液压致动系统还结合到一组脚踏板（例如，106,108）中。

公开(公告)号：WO1994019048A1

公开(公告)日：1994-09-01

申请号：PCT/EP1994000525

申请日：1994-02-23

Applicant: KLINIKUM DER ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG ,  LIEKE, Michael

Inventor： KLINIKUM DER ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG

IPC: A61M25/01

CPC classification number: A61M25/0122

Abstract: The invention concerns a catheter, in particular for insertion into blood vessels, hollow organs and similar hollow bodies, the catheter having distal apertures which act as outlet ports for a propellant fluid. The positioning of such catheters inside a patient's body often turns out to be difficult and, since the catheter can only be positioned with the help of X-ray transillumination, this results in exposure of all concerned to radiation. In order to keep radiation-exposure levels as low as possible and to be able to move the catheter easily and as rapidly as possible, the invention calls for the flow of propellant fluid out of each of the outlet ports to be controlled independently.

公开(公告)号：WO2015191646A1

公开(公告)日：2015-12-17

申请号：PCT/US2015/034987

申请日：2015-06-09

Applicant: INCEPTUS MEDICAL, LLC

Inventor： QUICK, Richard

IPC: A61M25/00 ,  A61M25/01 ,  A61M25/10

CPC classification number: A61B17/221 ,  A61B2017/0046 ,  A61B2017/00557 ,  A61B2017/22034 ,  A61B2017/22061 ,  A61B2017/22079 ,  A61B2017/22094 ,  A61B2017/2212 ,  A61B2017/2215 ,  A61B2217/005 ,  A61F2/95 ,  A61F2002/9528 ,  A61M25/0082 ,  A61M25/0113 ,  A61M25/0122 ,  A61M2210/0693 ,  A61M2210/12

Abstract: Retraction and aspiration devices, systems, and methods are disclosed herein. One aspect of the present technology, for example, is directed toward an apparatus for use with, a catheter system configured to enable intravascular delivery of an interventional device to a treatment site in a blood vessel. The apparatus can include a housing configured to be releasably coupled to a proximal portion of the catheter system and an actuation mechanism coupled to the housing. The actuation mechanism can include a lever movably coupled to the housing, a locking portion configured to engage a portion of the catheter system, and a pressure source coupled to the housing and the actuation mechanism. Movement of the lever simultaneously activates the pressure source to generate pressure, and moves the locking portion to engage and retract at least a portion of the catheter system.

Abstract translation: 本文公开了收缩和抽吸装置，系统和方法。 本技术的一个方面，例如，涉及一种用于与导管系统一起使用的装置，导管系统被配置为使介入装置的血管内递送到血管中的治疗部位。 该装置可以包括构造成可释放地联接到导管系统的近端部分的壳体和联接到壳体的致动机构。 致动机构可以包括可移动地联接到壳体的杆，构造成接合导管系统的一部分的锁定部分和联接到壳体和致动机构的压力源。 杆的移动同时启动压力源以产生压力，并且移动锁定部分以接合和缩回导管系统的至少一部分。

公开(公告)号：WO2010067386A1

公开(公告)日：2010-06-17

申请号：PCT/IT2008/000753

申请日：2008-12-10

Applicant: ERA ENDOSCOPY S.r.l. ,  GORINI, Samuele ,  PERNORIO, Giuseppe ,  ARENA, Alberto

Inventor： GORINI, Samuele ,  PERNORIO, Giuseppe ,  ARENA, Alberto

IPC: A61B1/00 ,  A61B1/31 ,  A61M25/01 ,  A61B1/273

CPC classification number: A61M25/0122 ,  A61B1/00156 ,  A61B1/0055 ,  A61B1/31

Abstract: An endoscopic device capable of autonomous locomotion through a body cavity with a pre-established direction of displacement, comprising a tubular body (1) made of an elastic material extending between two, front (2) and rear (3) end portions respectively comprising pneumatically actuated anchoring means (4) for temporarily and alternately attaching said end portions to the wall of the body cavity in synchronism with corresponding axial extensions and contractions of the tubular body. The tubular body incorporates a reinforcement structure (6, 7) distributed along its length that is substantially rigid in the radial direction and yielding in the axial direction. The tubular body wall is formed by superimposed inner (9) and outer (10) layers, the reinforcement structure being incorporated therebetween. Through openings (11, 12, 13) are formed on the outer layer for allowing air possibly entered between the inner layer and the outer layer from the inside of the tubular body to be discharged to the outside.

Abstract translation: 一种内窥镜装置，其能够通过具有预先确定的位移方向的体腔进行自主运动，所述内窥镜装置包括由弹性材料制成的管状体（1），所述管状体在两个前部（2）和后部（3）端部之间分别包括气动 致动的锚固装置（4），用于与管状体的对应的轴向延伸和收缩同步地暂时且交替地将所述端部附接到体腔的壁。 管状体包括沿其长度分布的加强结构（6,7），该加强结构在径向上基本上是刚性的并且在轴向上产生。 管状体壁由叠加的内部（9）和外部（10）层形成，加强结构被结合在其间。 通过开口（11,12,13）形成在外层上，用于允许从管状体的内部可能进入内层和外层之间的空气排出到外部。

公开(公告)号：WO2009135251A1

公开(公告)日：2009-11-12

申请号：PCT/AU2009/000555

申请日：2009-05-05

Applicant: ENDOGENE PTY LTD ,  SOUTORINE, Mikhail

Inventor： SOUTORINE, Mikhail

IPC: A61M25/085 ,  A61M25/01 ,  F16L55/00

CPC classification number: A61B1/00156 ,  A61M25/003 ,  A61M25/0032 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/01 ,  A61M25/0122 ,  A61M2025/0034 ,  A61M2025/0036 ,  A61M2025/006

Abstract: Some embodiments relate to an apparatus comprising an elongate flexible tube sized to be received within a tract and having a proximal end and a distal end; a drive mechanism coupled to the proximal end of the tube; and a liquid column extending from the proximal end to the distal end; wherein the drive mechanism is configured to cause movement of the liquid column within the tube to impart forward momentum to the tube and thereby promote advancement of at least the distal end of the tube within the tract when at least the distal end is received within a part of the tract.

Abstract translation: 一些实施例涉及一种包括细长柔性管的装置，其尺寸被设计成容纳在管道内并且具有近端和远端; 耦合到所述管的近端的驱动机构; 以及从所述近端延伸到所述远端的液柱; 其中所述驱动机构构造成使所述液柱在所述管内移动以向所述管施加向前的动量，从而当所述至少所述远端被接收在所述管的一部分内时促进所述管内至少所述管的所述远端的前进 的道路。

公开(公告)号：WO2006012421A3

公开(公告)日：2009-04-02

申请号：PCT/US2005025888

申请日：2005-07-20

Applicant: ST JUDE MEDICAL ATRIAL FIBRILL ,  KNUDSON JOHN C ,  FORSBERG ANDREW T

Inventor： KNUDSON JOHN C ,  FORSBERG ANDREW T

IPC: A61M31/00

CPC classification number: A61M25/0122 ,  A61B18/1492 ,  A61B2017/003 ,  A61B2017/00539 ,  A61B2018/1465 ,  A61M25/0136 ,  A61M25/0155

Abstract: A hydraulically assisted actuator in a handle (e.g., 6) connects with a catheter having a deflectable distal ablation tip (e.g., 64). The hydraulic actuator translates small mechanical movement by a clinician into large travel movements of connected steering cables (e.g., 38, 40) and increased tension in the ablation tip for greater deflection. The hydraulic system further dampens the return of the ablation tip from a deflected position to an equilibrium position. The hydraulic actuation system is also incorporated into a set of foot pedals (e.g., 106, 108).

Abstract translation: 手柄（例如6）中的液压辅助致动器与具有可偏转远端消融尖端（例如64）的导管连接。 液压执行器将临床医生的小机械运动转换成连接的转向电缆（例如38,40）的大的行进运动，并且在消融尖端中增加张力以实现更大的偏转。 液压系统进一步抑制消融尖端从偏转位置返回到平衡位置。 液压致动系统也被结合到一组脚踏板（例如，106,108）中。