摘要:
Main chain polyamines comprise amine and ammonium groups along the polymer backbone. Main chain polyamines can be used as pharmaceutical agents and in pharmaceutical compositions. The main chain polyamines are particularly useful in the treatment or prevention of mucositis and infection, specifically oral mucositis and surgical site infection.
摘要:
The present invention relates generally to substrates for making polymers and methods for making polymers. The present invention also relates generally to polymers and devices comprising the same.
摘要:
alpha-Aminoamidine polymers and methods of preparing a-aminoamidine polymers by reacting by reacting one or more amines with one or more isocyanides and one or more aldehydes are described. Methods of preparing a-aminoamidine polymers from commercially available starting materials are also provided, wherein the starting materials are racemic or stereochemically pure. a-Aminoamidine polymers or salt forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems and for other purposes as well such as, for example, coatings, additives, excipients, plastics, and materials, etc. Given the amino moiety of these alpha-aminoamidine polymers, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive alpha-aminoamidine polymers and polynucleotides can be prepared. The inventive alpha-aminoamidine polymers may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.
摘要:
Die vorliegende Erfindung betrifft neuartige Polyamine mit sekundären Aminogruppen, ein Verfahren zu deren Herstellung, Addukte dieser Polyamine und deren Verwendungen. Die Polyamine lassen sich auf einfache Art und Weise aus leicht zugänglichen Edukten herstellen. Sie und ihre Addukte zeichnen sich insbesondere durch eine niedrige Viskosität aus und sind geeignet als Bestandteil von Polyurethan- und Polyharnstoff-Zusammensetzungen mit ausgezeichneter Verarbeitbarkeit und hoher Flexibilität, sowie als Bestandteil von Epoxidharz-Zusammensetzungen, insbesondere Beschichtungen.
摘要:
Verfahren zur Herstellung von polymeren, ionischen Imidazoliumverbindungen, dadurch gekennzeichnet, dass -eine α-Dicarbonylverbindung, -ein Aldehyd -mindestens eine Aminoverbindung mit mindestens zwei primären Aminogruppen, -gegebenenfalls eine Aminoverbindung mit nur einer primären Aminogruppe und eine -Wasserstoffsäure, wobei die Carbonylgruppen der α-Dicarbonylverbindung und des Aldehyds gegebenenfalls auch als Halbacetal, Acetal bzw. Halbketal oder Ketal vorliegen können, miteinander umgesetzt werden.
摘要:
The aim of the invention is to produce polymeric networks. An aldehyde or a mixture of aldehydes or precursors thereof are condensed with a component (A) that contains amines, optionally in the presence of a solvent (S). The component (A) contains at least one amine (I) which can be obtained by means of amination of polymeric ethers of the 1.4 butanediol and is provided with at least two free amino groups. Said component (A) also and optionally contains at least one amine of the formula (II): Y (-NH2)n and optionally contains at least one amine of the formula (III): (Z-)(q-r)Y (-NH2)r, wherein Y means n-valued organic radicals, Y means q-valued organic radicals, Z means functional single-valued radicals, n means an integral value of 1 to 20, q means an integral value of 2 to 20 and r means an integral value of 1 to 19 with the proviso that 1
摘要:
A stabilised aqueous formazin composition comprises 100 parts by weight water; up to 0.03 parts by weight formazin polymer; 0.4to 5parts by weight hexamethylenetetramine;and a buffer composition, wherein the buffer composition is adjusted to maintain a pH of the formazin solution in a range between 8.4and 10. The stabilised formazin composition has a turbidity of 400 NTU or less.A diluent for preparing the stabilised formazin composition from a formazin stock composition is provided, wherein the diluent comprises hexamethylenetetramine in a concentration of between 4and 50 g/l and a buffer composition adjusted to a pH of the diluent in a range of from 8.4to 10.
摘要:
A corrosion inhibitor composition useful in pipes, pilings and hulls comprising the reaction product of a vinyl/vinylidene-terminated polyolefin having at least 14 carbon atoms and a polyamine having a molecular weight of at least 500 g/mole.