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    POLYOLS FROM PROTEIN BIOMASS
    2.
    发明申请
    POLYOLS FROM PROTEIN BIOMASS 审中-公开
    蛋白质生物质的多糖

    公开(公告)号：WO2016094859A1

    公开(公告)日：2016-06-16

    申请号：PCT/US2015/065374

    申请日：2015-12-11

    Applicant: NARAYAN, Ramani ,  GRAIVER, Daniel ,  HABLOT, Elodie

    Inventor： NARAYAN, Ramani ,  GRAIVER, Daniel ,  HABLOT, Elodie

    IPC: C08G18/00

    CPC classification number: C08H1/00 ,  C07K1/1077 ,  C08G18/5039 ,  C08G18/5045 ,  C08G71/04 ,  C08J2389/00 ,  C08L89/00

    Abstract: A process of producing multi-hydroxy polyols, the process comprising providing a biomass material and transamidating the biomass material with an amine selected from the group consisting essentially of a diamine and an alkanolamine, to provide low molecular weight derived amino-acids or derived oligomers of proteins. Thereafter, reacting the derived amino-acids or derived oligomers with a carbonate to provide hydroxyl terminated urethane oligomers.

    Abstract translation: 一种生产多羟基多元醇的方法，该方法包括提供生物质材料并使选自基本上由二胺和链烷醇胺组成的组中的胺转酰胺化生物质材料，以提供低分子量衍生的氨基酸或衍生的低聚物 蛋白质。 此后，使衍生的氨基酸或衍生的低聚物与碳酸酯反应，得到羟基封端的氨基甲酸酯低聚物。

    COMPOSITIONS AND METHODS RELATED TO PROTEINS CAPABLE OF REVERSIBLE TRANSITION TO A MELT
    5.
    发明申请
    COMPOSITIONS AND METHODS RELATED TO PROTEINS CAPABLE OF REVERSIBLE TRANSITION TO A MELT 审中-公开
    与可逆转向蛋白质相关的蛋白质的组合物和方法

    公开(公告)号：WO2014160131A1

    公开(公告)日：2014-10-02

    申请号：PCT/US2014/025887

    申请日：2014-03-13

    Applicant: THE PENN STATE RESEARCH FOUNDATION

    Inventor： DEMIREL, Melik ,  PENA-FRANESCH, Abdon

    IPC: C08L89/00 ,  C09J189/00

    CPC classification number: C08L89/00 ,  C07K14/43504 ,  C08J3/03 ,  C08J3/09 ,  C08J3/18 ,  C08J2389/00 ,  C08K5/0016 ,  C08L3/02 ,  C08L2201/54 ,  C08L2203/12 ,  C08L2203/16 ,  C09J5/00 ,  C09J189/00 ,  C09J2489/00

    Abstract: Provided are compositions and methods for making a variety of products. The methods involve mixing sucker ring teeth (SRT) protein and a plasticizer or a solvent to obtain a mixture of the SRT protein and the plasticizer. When the SRT is mixed with a plasticizer it is heated to betwee 32°C and 195°C to obtain an SRT protein melt. The melt is used to form a wide variety of products. When the SRT is mixed with a solvent, such as an organic solvent or an aqueous solvent, a solution of the SRT protein is formed, and is subsequently used to forming a product from the solution, wherein the product contains SRT protein.

    Abstract translation: 提供制造各种产品的组合物和方法。 该方法包括混合吸盘齿（SRT）蛋白和增塑剂或溶剂以获得SRT蛋白和增塑剂的混合物。 当SRT与增塑剂混合时，将其加热至32℃至195℃，得到SRT蛋白质熔体。 熔体用于形成各种各样的产品。 当SRT与溶剂如有机溶剂或水性溶剂混合时，形成SRT蛋白质溶液，随后用于从溶液中形成产物，其中产物含有SRT蛋白质。

    PROCESS FOR PRODUCING POLYMER FOAMS
    7.
    发明申请
    PROCESS FOR PRODUCING POLYMER FOAMS 审中-公开
    生产聚合物助剂的方法

    公开(公告)号：WO2014102708A2

    公开(公告)日：2014-07-03

    申请号：PCT/IB2013/061278

    申请日：2013-12-23

    Applicant: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA

    Inventor： FRAGOULI, Despina ,  MELE, Elisa ,  ATHANASIOU, Athanasia

    IPC: C08J9/00 ,  C08J9/26 ,  A61L27/44

    CPC classification number: C08J9/26 ,  A61L27/48 ,  A61L27/56 ,  A61L2400/08 ,  C08J9/0061 ,  C08J9/36 ,  C08J2201/046 ,  C08J2201/0464 ,  C08J2205/022 ,  C08J2205/05 ,  C08J2333/06 ,  C08J2375/04 ,  C08J2383/04 ,  C08J2389/00 ,  C08J2400/14 ,  C08J2401/02 ,  C08J2405/04 ,  C08J2405/08 ,  C08J2431/04 ,  C08J2433/26 ,  C08J2477/06

    Abstract: Process for the production of a polymer foam with use of hydrogel pearls as porosity generating template, comprising the steps of: - providing a matrix of polymer or prepolymer in viscous state including, as a dispersed phase, hydrogel pearls, where said pearls are dispersed in said matrix so as to generate intercommunicating cells, - causing the solidification of the matrix of polymer or prepolymer to obtain said polymer foam including said hydrogel pearls, characterised in that it comprises the operation of subjecting the thus obtained foam to conditions which cause the dehydration of said hydrogel pearls so as to obtain a reduction of volume of said pearls and - removing the dehydrated pearls by immersion in water of the polymer foam or by exposure of the foam to a flow of pressurized gas or water.

    Abstract translation: 使用水凝胶珍珠作为孔隙产生模板生产聚合物泡沫的方法，包括以下步骤： - 提供粘性状态的聚合物或预聚物基质，包括分散相，其中所述珍珠分散在 所述基质以产生相互连通的细胞， - 使聚合物或预聚物基质固化得到包括所述水凝胶珍珠的所述聚合物泡沫体，其特征在于，其包括将由此获得的泡沫体经受使引起脱水的条件的操作 所述水凝胶珍珠，以便减少所述珍珠的体积，以及 - 通过浸入聚合物泡沫的水中或通过将泡沫暴露于加压气体或水的流中去除脱水珍珠。

    SPRAY DRY METHOD FOR ENCAPSULATION OF BIOLOGICAL MOIETIES AND CHEMICALS IN POLYMERS CROSS-LINKED BY MULTIVALENT IONS FOR CONTROLLED RELEASE APPLICATIONS
    8.
    发明申请
    SPRAY DRY METHOD FOR ENCAPSULATION OF BIOLOGICAL MOIETIES AND CHEMICALS IN POLYMERS CROSS-LINKED BY MULTIVALENT IONS FOR CONTROLLED RELEASE APPLICATIONS 审中-公开
    用于控制释放应用的多重离子交联的聚合物中生物活性物质和化学物质的喷雾干燥方法

    公开(公告)号：WO2013096883A2

    公开(公告)日：2013-06-27

    申请号：PCT/US2012071447

    申请日：2012-12-21

    Applicant: UNIV CALIFORNIA

    Inventor： JEOH-ZICARI TINA ,  SCHER HERBERT B ,  SANTA-MARIA MONICA C

    IPC: B29C67/06

    CPC classification number: A61K9/5036 ,  A61K9/1694 ,  A61K9/5089 ,  A61K38/385 ,  A61K38/47 ,  A61K47/30 ,  B01J13/043 ,  B01J13/046 ,  C08J3/122 ,  C08J3/24 ,  C08J2305/04 ,  C08J2305/06 ,  C08J2389/00 ,  C12Y302/01004 ,  C12Y302/01008

    Abstract: Microencapsulation of bioactive and chemical cargo in a stable, cross-linked polymer matrix is presented that results in small particle sizes and is easily scaled-up for industrial applications. A formulation of a salt of an acid soluble multivalent ion, an acid neutralized with a volatile base and one or more monomers that cross-link in the presence of multivalent ions is atomized into droplets. Cross-linking is achieved upon atomization where the volatile base is vaporized resulting in a reduction of the pH of the formulation and the temporal release of multivalent ions from the salt that cross-link the monomers forming a capsule. The incorporation of additional polymers or hydrophobic compounds in the formulation allows control of hydration properties of the particles to control the release of the encapsulated compounds. The operational parameters can also be controlled to affect capsule properties such as particle-size and particle-size distribution.

    Abstract translation: 提出了生物活性和化学货物在稳定的交联聚合物基质中的微胶囊化，其导致小的颗粒尺寸并且易于放大用于工业应用。 酸溶性多价离子盐，用挥发性碱中和的酸和在多价离子存在下交联的一种或多种单体的配方被雾化成液滴。 交联是在雾化时实现的，其中挥发性碱被汽化，导致制剂的pH降低，并且多价离子从与形成胶囊的单体交联的盐的时间释放。 在制剂中加入另外的聚合物或疏水性化合物可以控制颗粒的水合性质以控制包封的化合物的释放。 还可以控制操作参数以影响胶囊性质，例如粒度和粒度分布。

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