摘要:
The invention relates to polymer materials suitable for use as sealants and adhesives. The polymer formulations provide elasticity, and moisture resistance. They may be employed as in-the-body sealants and adhesives, or alternatively placed against skin, and may secure medical appliances.
摘要:
Polymers with improved bioadhesive properties and methods for improving bioadhesion of polymers have been developed. Such bioadhesive polymers can be stabilized against erosion, particularly in the gastrointestinal tract, by incorporating one or more additives selected from (1) polyanhydrides, such as those having a molecular weight average in excess of 20,000, (2) acidic components, (3) metal compounds, (4) stabilizing polymers, and (5) hydrophobic components. By stabilizing bioadhesive polymers against erosion, residence time at tissue surfaces can be further increased. The stabilized polymers are also useful to maintain the drug release rate-controlling properties for a prolonged period of time.
摘要:
Chemically anchoring long-chain polymer networks of tough hydrogels on solid surfaces can represent a general strategy to design tough and functional bonding between hydrogels and solid materials, achieving interfacial toughness over 1000 Jm-2.
摘要:
Polymers with improved bioadhesive properties and methods for improving bioadhesion of polymers have been developed. Such bioadhesive polymers can be stabilized against erosion, particularly in the gastrointestinal tract, by incorporating one or more additives selected from (1) polyanhydrides, such as those having a molecular weight average in excess of 20,000, (2) acidic components, (3) metal compounds, (4) stabilizing polymers, and (5) hydrophobic components. By stabilizing bioadhesive polymers against erosion, residence time at tissue surfaces can be further increased. The stabilized polymers are also useful to maintain the drug release rate-controlling properties for a prolonged period of time.
摘要:
Polymeric materials are disclosed herein that include a reaction product of components comprising: a) a first amine component having at least two and at most three primary amino groups, secondary amino groups, or a mixture thereof, with the proviso that the first amine component is not a silicone diamine; b) a second amine component having (i) greater than three primary amino groups, or (ii) at least three primary amino groups and a plurality of secondary amino groups, wherein the second amine component is a polymeric material having a carbon backbone or a polymeric material having a carbon backbone with a plurality of catenated nitrogen atoms; and c) an oxalate ester.
摘要:
Polymeric materials are disclosed herein that include a Polymer A, a Polymer B, and an oxalate ester or reaction product thereof. Polymer A contains electrophilic reactive groups, and Polymer B contains nucleophilic groups. In certain embodiments, the polymeric materials are free-flowing liquids at 100% solids that can be used, for example, as topical skin adhesives.
摘要:
The present application relates to a resin composition and in particular to a light-curable resin composition. It is known to achieve a thixotropic behavior of an adhesive composition by adding an inorganic additive like fumed silica. Adding inorganic additives results in significant particle problems as fumed silica is a solid particle and affects the optical performance of the adhesive composition. In accordance with the invention a particle free resin composition with a thixotropic behavior is provided. The inventive composition comprises a) 30 to 90 wt% of a urethane acrylate oligomer with a molecular weight greater than 15000, b) 2 to 40 wt% of a (meth)acrylate monomer having a benzene ring, and c) 0,2 to 10 wt% of a photo initiator.