PHASED SENSOR SYSTEM WITH MULTIPLE PARALLEL PRECONCENTRATORS
    3.
    发明申请
    PHASED SENSOR SYSTEM WITH MULTIPLE PARALLEL PRECONCENTRATORS 审中-公开
    具有多个并行预处理器的相传传感器系统

    公开(公告)号:WO2004038400A3

    公开(公告)日:2005-03-24

    申请号:PCT/US0330458

    申请日:2003-09-26

    Inventor: BONNE ULRICH

    Abstract: A micro fluid analyzer (500, 600, 610, 620) having a concentrator (523, 623) and two separators (524, 525, 624, 625, 651, 654). The analyzer may have one or two pumps(521, 522, 640, 621, 622). The analyzer (500) may have a hyper pre-concentrator (526) having a number of channels (527). There are numerous detectors (531, 532, 533, 534, 631, 632, 633, 634) positioned along the flow path of the analyzer. Also, one or more orifices (541, 542, 644, 645, 647, 648, 653, 656) and micro valves (641, 541, 661) may be positioned in the flow path. The concentrator (523, 623) may have an array of heater elements (20, 22, 24, 26) that provide a heat pulse that moves along the fluid path to provide an increasing concentration of heat in a fluid. The analyzer may be configured as a multiple fluid or gas chromatograph.

    Abstract translation: 具有集中器(523,623)和两个分离器(524,525,624,625,651,654)的微流体分析器(500,600,610,620)。 分析器可以具有一个或两个泵(521,522,640,621,622)。 分析器(500)可以具有具有多个通道(527)的超预浓缩器(526)。 存在沿着分析器的流动路径定位的多个检测器(531,532,533,534,631,632,633,634)。 而且,可以在流动路径中定位一个或多个孔口(541,542,644,645,647,648,663,656)和微小阀门(641,541,661)。 集中器(523,623)可以具有提供沿着流体路径移动以提供流体中增加的热量浓度的加热脉冲的加热器元件阵列(20,22,24,26)。 分析仪可以配置为多重流体或气相色谱仪。

    THERMOPHORETIC PUMP AND CONCENTRATOR
    4.
    发明申请
    THERMOPHORETIC PUMP AND CONCENTRATOR 审中-公开
    热塑泵和浓缩器

    公开(公告)号:WO0061261A3

    公开(公告)日:2001-03-01

    申请号:PCT/US0006010

    申请日:2000-03-08

    Abstract: The method and apparatus of the invention create a dynamic Soret effect for propelling a target chemical constituent along a pathway. A moving temperature profile impressed upon the pathway produces consecutive alternating warmer and cooler zones along the path which transport components of a mixture down the path according to their respective diffusivities. In one embodiment, the invention provides a dynamic thermophoretic concentrator for separating a target chemical constituent from a mixture of components on the basis of diffusion coefficient by using alternate forward and backward motion of a temperature profile along the pathway, thereby accumulating an ultimate concentration of the target constituent greater than its initial concentration in the mixture.

    Abstract translation: 本发明的方法和装置产生用于沿着途径推进目标化学成分的动态Soret效应。 沿路径移动的移动温度曲线沿着路径产生连续交替的加热器和冷却器区域,该区域根据它们各自的扩散率将混合物的成分沿道路传输。 在一个实施方案中,本发明提供了一种动态热解聚焦器,用于通过使用沿着路径的温度分布的交替的向前和向后运动,基于扩散系数从组分混合物中分离目标化学成分,从而累积最终浓度 目标成分大于其混合物中的初始浓度。

    SPATIAL TEMPERATURE GRADIENTS IN LIQUID CHROMATOGRAPHY
    6.
    发明申请
    SPATIAL TEMPERATURE GRADIENTS IN LIQUID CHROMATOGRAPHY 审中-公开
    液相色谱中的空间温度梯度

    公开(公告)号:WO2016138208A1

    公开(公告)日:2016-09-01

    申请号:PCT/US2016/019471

    申请日:2016-02-25

    CPC classification number: G01N30/30 G01N30/34 G01N2030/3015 G01N2030/3076

    Abstract: Methods for focusing analyte peaks in liquid chromatography using a spatial temperature gradient are provided. Also provided are methods for focusing analyte peaks and improving resolution using a trap column upstream of a separation column. Further, methods are provided in which the trap column placed upstream of the separation column is packed with a temperature- sensitive polymer/copolymer, and a spatial temperature gradient is applied along the trap column for obtaining improved retentivity by trap column stationary phase, and overall improved resolution of analyte peaks.

    Abstract translation: 提供了使用空间温度梯度在液相色谱中聚焦分析物峰的方法。 还提供了用于聚焦分析物峰的方法,并使用分离塔上游的捕获柱来提高分辨率。 此外,提供了设置在分离塔上游的捕集塔填充温度敏感性聚合物/共聚物的方法,并且沿着捕集塔施加空间温度梯度以通过陷阱柱固定相获得改进的保持性,并且总体上 提高分析物峰的分辨率。

    PHASED MICRO ANALYZER
    7.
    发明申请
    PHASED MICRO ANALYZER 审中-公开
    PHASED微分析仪

    公开(公告)号:WO2006073434A3

    公开(公告)日:2006-12-28

    申请号:PCT/US2005013804

    申请日:2005-04-21

    Inventor: BONNE ULRICH

    Abstract: A micro fluid analyzer that may be highly sensitive, fast and very compact. The analyzer may use sufficiently low power per analysis to be easily implemented with an equivalently small battery pack or other portable power source. There may be energy conservation features in the analyzer, such as optimal adsorber film thicknesses in the pre-concentrator, concentrator and chromatographic separators. There may be special timing of the phased heating elements in the concentrators and separators to further reduce energy consumption. Various kinds of detectors and sensors may be incorporated in the analyzer for achieving low probability for false positives and detection versatility. There may be a controller that provides data acquisition and analyses, drive signals for control, management of wireless signal transmission and reception, processing, and other operational uses of the micro analyzer.

    Abstract translation: 微流体分析仪可能是高度敏感,快速和非常紧凑的。 分析仪可以使用相当小的电池组或其他便携式电源来容易地实现每个分析的足够低的功率。 在分析仪中可能存在节能特征,例如预浓缩器,浓缩器和色谱分离器中的最佳吸附膜厚度。 集中器和分离器中的相位加热元件可能存在特殊的时机,以进一步降低能量消耗。 可以在分析器中并入各种检测器和传感器,以实现误报的概率和检测多样性。 可能有一个控制器提供数据采集和分析,驱动信号进行控制,无线信号传输和接收的管理,处理以及微分析仪的其他操作使用。

    GAS SENSOR WITH PHASED HEATERS FOR INCREASED SENSITIVITY
    9.
    发明申请
    GAS SENSOR WITH PHASED HEATERS FOR INCREASED SENSITIVITY 审中-公开
    带有相位加热器的气体传感器提高了灵敏度

    公开(公告)号:WO0107903A3

    公开(公告)日:2001-08-16

    申请号:PCT/US0019924

    申请日:2000-07-20

    Applicant: HONEYWELL INC

    Abstract: A concentrator and sensor assembly are disclosed that use phased heaters to multiply the concentration levels that can be eluted, relative to operation with a single interactive element having a sorbent material to increase the concentration of desired gas constituents at a detector. This is accomplished here by providing two or more interactive concentrator elements that are selectively heated in a time phased sequence so that each of the interactive elements becomes heated and desorbs gas constituents into the sample fluid stream at substantially the same time that an upstream concentration pulse, produced by heating one or more upstream interactive elements, reaches the interactive element. This produces a multiplication effect that significantly increases the concentration of the gas constituents at the detector, thereby increasing the effective sensitivity of the detector.

    Abstract translation: 公开了一种浓缩器和传感器组件,其相对于使用具有吸附剂材料的单个相互作用元件的操作,使相变加热器倍增可以被洗脱的浓度水平,以增加检测器处期望的气体组分的浓度。 这通过提供两个或更多个交互式集中器元件来实现,所述交互式集中器元件以时间相位顺序被选择性地加热,使得每个交互式元件被加热并且在基本上与上游浓度脉冲相同的时间将气体成分解吸到样品流体流中, 通过加热一个或多个上游交互元素而产生,到达交互元素。 这产生了显着增加检测器处气体成分浓度的增殖效应,从而增加了检测器的有效灵敏度。

    CHROMATOGRAPH WITH COLUMN EXTRACTION
    10.
    发明申请
    CHROMATOGRAPH WITH COLUMN EXTRACTION 审中-公开
    色谱柱提取

    公开(公告)号:WO98050129A1

    公开(公告)日:1998-11-12

    申请号:PCT/US1998/009165

    申请日:1998-05-05

    Abstract: A gas chromatograph (2) and method of chromatography are provided. Analytes (112), those compounds to be tested, are extracted from a sample by moving the sample into a column (100) which has a stationary phase (109) along column walls (110). Column (100) has two sections (101, 102) which are different in length. Longer section (101) is heated and analytes (112) move to shorter section (102). Longer section (101) is then cooled and the entire column (100) is heated. The device then functions as an analytical column and analytes (112) move out of shorter section (102) through longer section (101) and out of column (100). A detector (111) placed at the end of the column's longer section (101) detects the presence of the compounds as they exit column (100). In an alternate embodiment two separate columns are provided. One column is used as the extraction column and the other is used as the analytical column.

    Abstract translation: 提供气相色谱仪(2)和色谱法。 通过将样品移动到沿着柱壁(110)具有固定相(109)的柱(100)中,从样品中提取待测试的化合物(112)。 柱(100)具有长度不同的两个部分(101,102)。 较长的部分(101)被加热并且分析物(112)移动到较短的部分(102)。 然后冷却较长的部分(101),并加热整个塔(100)。 然后,该装置用作分析柱,分析物(112)通过较长部分(101)和列(100)从较短部分(102)移出。 放置在色谱柱较长部分(101)末端的检测器(111)在离开色谱柱(100)时检测化合物的存在。 在替代实施例中,提供了两个单独的列。 一列用作萃取柱,另一列用作分析柱。

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