Abstract:
Techniques disclosed herein can be used to perform a rapid, splitless injection of a sample including SVOCs and VOCs. In some embodiments, a system includes two focusing traps combined in series, one inside of a GC oven and one in a separate oven to concentrate the SVOCs inside of the GC oven and concentrate the VOCs outside of the GC oven. Heating the VOC focusing trap and reversing the flow through both focusers allows splitless injection of compounds boiling from as low as -100 ⁰C to as high as 600 ⁰C in a single analysis, with a narrow injection bandwidth to optimize both sensitivity and the resolving power of the analyzer.
Abstract:
The present disclosure discusses a method of separating a sample including oligonucleotides including coating a flow path of a chromatographic system; injecting the sample comprising oligonucleotides into the chromatographic system; flowing the sample through the chromatographic system; and separating the oligonucleotides. In some examples, the coating of the flow path is non-binding with respect to the analyte, such as oligonucleotides. Consequently, the analyte does not bind to the coating of the flow path. The non-binding coating eliminates the need for passivation, which can eliminate the formerly needed time to passivate as well. In addition, analyte can be recovered with a first injection in a system, such as chromatographic system.
Abstract:
The disclosure pertains to a tubing and ferrule assembly for use in joining a clad tubing to a fitting. The ferrule is bound to the clad tubing, which includes a partial jacket of stainless steel, such, that the inert core protrudes from, and has a common outer diameter with, the jacket. The ferrule is bound to the jacket slightly more distant than necessary for the inert core to contact a String. When the ferrule is retained in place, the inert core is compressed and provides a true zero dead volume connection between the clad tubing and the fitting. The relationship of the ferrule, the clad tubing, and the fitting limits the position of the clad tubing and therefore precludes damaging of the associated valve or component.
Abstract:
A significant reduction in extra-column band broadening can be achieved by decoupling the injection system from the main solvent flow line. In addition, by decoupling the injection system from the main solvent flow line, additional components (e.g., filters, valves, etc.) can be introduced into the chromatography system without increasing the negative band broadening effects. Systems and methods herein provide not only for such decoupling but also for filtering precipitates from the system. As a result, a larger volume of sample can be injected into the present systems without compromising separation yield. In addition, an increase the column loading per batch, an increase the overall yield of separations, and greater system efficiency (i.e., less time lost for cleaning and maintenance) can be realized.
Abstract:
본 발명은 전지 내부의 가스를 포집한 후, 개폐 밸브로 조절하여 포집된 가스의 일부를 가스 시료로 내보내는 가스포집관; 가스 크로마토그래피로 주입되는 가스 시료를 포집하는 가스샘플링 루프; 가스샘플링 루프에 채워진 가스 시료를 운반가스를 이용하여 크로마토그래피의 컬럼으로 주입하도록 조절하는 제1 스위칭 밸브; 상기 가스포집관과 연결되고, 상기 가스 시료가 상기 가스샘플링 루프로 확산하도록 조절하는 제2 스위칭 밸브; 및 상기 가스샘플링 루프를 진공 갑압하는 진공펌프;를 포함하는 가스 크로마토그래피분석을 위한 가스시료 주입장치 및 이를 이용한 주입 방법에 관한 것이다.
Abstract:
A sample injector (40) configured to introduce a sample fluid into a mobile phase, wherein the mobile phase is to be driven by a mobile phase drive (20) through a separation unit (30) for separating compounds of the sample fluid in the mobile phase, wherein the sample injector (40) comprises a metering device (100) being operable for intaking a metered amount of the sample fluid into the sample injector (40), and a fluidic valve (90)being switchable for operating the sample injector (40) selectively in a flushing mode (600; 1300, 1500) in which the metering device (100) is switched at least temporarily into fluid communication with the mobile phase drive (20) so that the metering device (100) is flushed by the mobile phase being delivered by the mobile phase drive (20), or a separation mode(500; 1200) in which the metering device (100) is switched out of a fluidic path between the mobile phase drive (20) and the separation unit (30) so that the sample fluid is driven between the mobile phase drive (20) and the separation unit (30) for separating the compounds.