公开(公告)号：WO2021202713A1

公开(公告)日：2021-10-07

申请号：PCT/US2021/025151

申请日：2021-03-31

Applicant: MEDTRONIC, INC.

Inventor： GHOSH, Subham

IPC: A61N1/362 ,  A61B5/349 ,  A61B5/00 ,  A61N1/375 ,  A61B5/282 ,  A61B5/339 ,  A61B5/367 ,  A61B5/388 ,  A61B5/4035 ,  A61B5/4052 ,  A61B5/6823 ,  A61B5/686 ,  A61B5/7475 ,  A61N1/36114 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/3756

Abstract: Systems and methods are described herein for determining whether cardiac conduction system pacing therapy may be beneficial and/or determining how proximal or distal a cardiac conduction system block may be using external cardiac signals. To do so, one or more left-sided metrics of electrical heterogeneity information may be generated based on left-sided surrogate cardiac electrical measured using a plurality of left external electrodes

公开(公告)号：WO2022027002A1

公开(公告)日：2022-02-03

申请号：PCT/US2021/070970

申请日：2021-07-27

Applicant: MEDTRONIC, INC.

Inventor： WHITMAN, Teresa A. ,  GARDESKI, Kenneth C. ,  CHRISTIE, Melissa G.T. ,  SIMHA, Narendra K. ,  PERSAUD, Neranjan ,  BREDEMEIER, Jennifer M. ,  MATTSON, Alexander R. ,  MORRIS, Marty M. ,  HOLM, Mikayle A.

IPC: A61N1/05 ,  A61M31/00 ,  A61M25/10 ,  A61B5/0035 ,  A61B5/055 ,  A61B6/032 ,  A61B6/504 ,  A61B6/5247 ,  A61M25/007 ,  A61M25/0108 ,  A61M25/09 ,  A61M25/1011 ,  A61M5/007 ,  A61N1/056 ,  A61N1/0563 ,  A61N1/057 ,  A61N1/3627 ,  A61N1/37512 ,  A61N1/3956 ,  A61N2001/058 ,  A61N2001/0585

Abstract: A system and method of implanting pacing lead in a patient's heart. The system may include a catheter configured to by inserted through the coronary sinus ostium such that the distal end region of the catheter is positioned past the anterolateral vein and proximate at least one septal perforating vein. The catheter is configured to inject contrast proximate the septal perforating vein to identify an implant region for a pacing lead. Further, a controller is configured to deliver pacing therapy to the implant region.

公开(公告)号：WO2021202711A1

公开(公告)日：2021-10-07

申请号：PCT/US2021/025149

申请日：2021-03-31

Applicant: MEDTRONIC, INC.

Inventor： GHOSH, Subham

IPC: A61N1/362 ,  A61B5/349 ,  A61B5/00 ,  A61N1/375 ,  A61B5/367 ,  A61B5/388 ,  A61B5/4035 ,  A61B5/4052 ,  A61B5/686 ,  A61N1/0404 ,  A61N1/36017 ,  A61N1/36031 ,  A61N1/36114 ,  A61N1/3625 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/3702 ,  A61N1/3756

Abstract: Systems and methods are described herein for determining whether a patient's cardiac conduction system or portions thereof are engaged by cardiac conduction system pacing therapy. One or more local metrics of electrical heterogeneity information may be generated based on surrogate cardiac electrical measured using a plurality of local external electrodes, which may be used to determine whether the patient's cardiac conduction system is engaged.

公开(公告)号：WO2022240669A1

公开(公告)日：2022-11-17

申请号：PCT/US2022/028007

申请日：2022-05-06

Applicant: MEDTRONIC, INC.

Inventor： ZHOU, Xiaohong ,  DEMMER, Wade M. ,  STADLER, Robert W.

IPC: A61N1/372 ,  A61N1/378 ,  A61N1/36 ,  A61N1/362 ,  A61N1/365 ,  A61N1/368 ,  A61N1/37 ,  A61N1/375 ,  A61N1/05 ,  A61N1/056 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/3684 ,  A61N1/36842 ,  A61N1/3712 ,  A61N1/3756 ,  A61N1/3787

Abstract: A medical device is configured to sense at least one cardiac electrical signal and generate pacing pulses according to a first pacing therapy by generating pacing pulses for delivery to a first combination of ventricular pacing sites including at least one ventricular conduction system pacing site. The medical device may be configured to determine a ventricular conduction condition based on a QRS signal feature of the sensed cardiac signal during the first pacing therapy. The medical device may change to a second pacing therapy different than the first pacing therapy based on the determined ventricular conduction condition.

公开(公告)号：WO2022208339A1

公开(公告)日：2022-10-06

申请号：PCT/IB2022/052878

申请日：2022-03-29

Applicant: IMPULSE DYNAMICS NV

Inventor： PRUTCHI, David ,  BEN DAVID, Tamir

IPC: A61N1/362 ,  A61N1/365 ,  A61N1/368 ,  A61N1/372 ,  A61B5/0245 ,  A61B5/065 ,  A61B5/287 ,  A61B5/346 ,  A61B5/4836 ,  A61N1/3627 ,  A61N1/36585 ,  A61N1/36842 ,  A61N1/3686 ,  A61N1/37258

Abstract: A method of cardiac signal processing including: receiving measurements from at least two electrodes positioned within the heart; determining, using the measurements, relative positioning of the at least two electrodes relative to each other; evaluating suitability of the relative positioning of the at least two electrodes for measurement of cardiac activity to determine which cardiac cycles should receive cardiac contractility modulation stimulation.