公开(公告)号：WO2022236332A2

公开(公告)日：2022-11-10

申请号：PCT/US2022/072184

申请日：2022-05-06

Applicant: COMPTON, Frances Benoist

Inventor： COMPTON, Frances Benoist

IPC: A61M1/28 ,  A61F2/958 ,  A61M1/36 ,  A61M25/01 ,  A61M25/04 ,  A61M1/3496 ,  A61M1/3659 ,  A61M2025/0031 ,  A61M2025/0057 ,  A61M25/003 ,  A61M25/0043 ,  A61M25/007 ,  A61M25/0097 ,  A61M25/0631 ,  A61M25/0693

Abstract: A catheter assembly includes a shaft with two non-communicating lumens for simultaneous inflow and outflow of fluids from a vein. A return lumen extends to an outlet assembly at the tip. A draw lumen includes an inlet assembly, proximally of the outlet assembly, with multiple openings to avoid blockage causing pressure elevation due to suction. The draw lumen has a larger crescent-shape profile while the return lumen has a smaller, circular profile within the arms of the crescent shape.

公开(公告)号：WO2022036168A2

公开(公告)日：2022-02-17

申请号：PCT/US2021/045863

申请日：2021-08-13

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： ISAACSON, S., Ray ,  BURKHOLZ, Jonathan, Karl ,  SCHERICH, Megan ,  BLANCHARD, Curtis, H. ,  LACKEY, John ,  HOPWOOD, Benjamin

IPC: A61M25/00 ,  A61M25/01 ,  A61M25/09 ,  A61B17/00234 ,  A61B17/3417 ,  A61B2017/00336 ,  A61M2025/0004 ,  A61M2025/0018 ,  A61M2025/0079 ,  A61M2025/0175 ,  A61M2025/09183 ,  A61M25/007 ,  A61M25/0074

Abstract: A vascular access device (10) to passively open a fluid path within a vasculature. The vascular access device (10) includes a catheter (20) and an obturator (50) slidably positioned within the lumen (32) of the catheter (20). The catheter (20) has a proximal end (22), a distal tip (24) comprising an opening (28) having an inner diameter and a sidewall (26) defining a lumen between the proximal end and distal tip. The obturator (50) has a distal end (52) with an outer diameter configured to form an interference fit with the inner diameter of the distal tip (24). The obturator may be positioned within the lumen to open various fluid pathways (36,38,72).

公开(公告)号：WO2021185931A2

公开(公告)日：2021-09-23

申请号：PCT/EP2021/056872

申请日：2021-03-17

Applicant: CIC FUND SECURITISATION S.A.

Inventor： MCINTYRE, Matthew ,  WALKER, Marshall ,  FALKNER, Peter

IPC: A61M25/00 ,  A61M27/00 ,  A61M25/04 ,  A61M2025/0019 ,  A61M2025/006 ,  A61M25/0017 ,  A61M25/007

Abstract: The present invention includes an indwelling urinary catheter operable for flushing fluid through the urethra. The catheter has an elongated tubular catheter body, a discharge lumen disposed within the catheter body operable for discharging urine from a patient, a fluid flush lumen disposed within the catheter body operable to receive a flushing fluid, and at least one permeable sheath in fluid communication with the fluid flush lumen, wherein a plurality of protrusions of variable shapes, sizes, and arrangements are disposed on the outer surface of the sheath and are operable to create space between the catheter body and the urethra for improved flushing. Alternative embodiments include circumferential ridges and eluting pores disposed on the outer surface of the sheath wherein the distance and height between the ridges as well as the density of the eluting pores decrease in the direction of the proximal end of the sheath.

公开(公告)号：WO2021126618A2

公开(公告)日：2021-06-24

申请号：PCT/US2020/063927

申请日：2020-12-09

Applicant: STRYKER CORPORATION ,  STRYKER EUROPEAN OPERATIONS LIMITED

Inventor： GERBERDING, Brent ,  CHEN, Hancun ,  LEYNOV, Aleksandr

IPC: A61M25/09 ,  A61M2025/09091 ,  A61M2025/09166 ,  A61M2025/09175 ,  A61M25/007

Abstract: A guidewire (100) includes: a shaft (110) having a proximal end (112), a distal end (114), and a body (116) extending from the proximal end (112) to the distal end (114); a blunt tip (182); and a sleeve (180); wherein the body of the shaft (110) comprises at least a segment (120) that is surrounded by the sleeve (180), the segment (120) coupled to the blunt tip (182); and wherein the segment (120) of the body of the shaft (110) comprises a flat portion (150, 400) having one or more openings (402) extending through a thickness of the flat portion (150, 400).

公开(公告)号：WO2021091804A8

公开(公告)日：2021-05-14

申请号：PCT/US2020/058462

申请日：2020-11-02

Applicant: MEDTRONIC, INC.

Inventor： BODNER, Jeffrey P.

IPC: A61M39/00 ,  A61M2025/006 ,  A61M2025/0073 ,  A61M2039/0009 ,  A61M2039/0273 ,  A61M2039/0276 ,  A61M2039/0282 ,  A61M25/0021 ,  A61M25/007 ,  A61M39/02 ,  A61M39/0247 ,  A61M5/14276

Abstract: A medical device configured to restrict medicament dispersion within a cerebrospinal fluid flow of the patient. The medical device including an implantable catheter having a distal end configured to be positioned within a flow of the cerebrospinal fluid, a proximal end, a body defining a lumen extending lengthwise along the implantable catheter configured to enable a flow of medicament from the proximal end to an infusion port located in proximity to the distal end, and a contoured surface defined by an exterior of the body in proximity to the infusion port configured to inhibit dispersion of the medicament within the cerebrospinal fluid.

公开(公告)号：WO2023069553A2

公开(公告)日：2023-04-27

申请号：PCT/US2022/047179

申请日：2022-10-19

Applicant: BARD ACCESS SYSTEMS, INC.

Inventor： SEPULVEDA, Juan ,  HOWELL, Glade, H.

IPC: A61M25/00 ,  A61M2025/0018 ,  A61M2025/0031 ,  A61M25/0009 ,  A61M25/001 ,  A61M25/0026 ,  A61M25/003 ,  A61M25/0043 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/0606

Abstract: The distal tip structure of a rapidly insertable central catheter (RICC) can be required to perform different functions from that of the remaining, multi-luminal section, of the RICC catheter. As such, the catheter body can be formed of a first material and the distal tip structure can be formed of a second material. Forming the RICC requires joining these two materials while maintaining a smooth abluminal surface. A bifurcated plug including a second material can be placed within a first lumen or second lumen of the catheter body. A mandrel can be placed within a third lumen. The assembly can then be placed within a die to plastically deform the bifurcated plug into a distal tip structure. Advantageously, only a single structure is required to plug the lumen and form the distal tip structure, reducing complexity and associated costs.

公开(公告)号：WO2023039551A2

公开(公告)日：2023-03-16

申请号：PCT/US2022/076241

申请日：2022-09-09

Applicant: WAYNE STATE UNIVERSITY

Inventor： HARRIS, Carolyn ,  ZARANEK, Mira ,  KHODADADEI, Fatemeh

IPC: A61L31/10 ,  A61L31/16 ,  A61K39/395 ,  C07K16/28 ,  A61B5/00 ,  A61F2/24 ,  A61K47/34 ,  A61M25/007 ,  A61M27/006 ,  A61M39/22 ,  A61M5/00 ,  A61M5/142 ,  F16K31/025 ,  F16K7/045

Abstract: This disclosure provides compositions, devices, systems, and methods that reduce the likelihood, amount, or level of cellular deposition (and associated blockage and/or failure) of implantable medical devices, such as central nervous system implants. Embodiments involve use of inhibitor(s) of one or more of TLR-4, TNF-α, IL-1β, or IL-6, for instance, to prevent, reduce, or reverse activation of astrocyte and/or glia cells, and/or to prevent, reduce, or reverse attachment of such cells to the surface of a medical device in contact with a biological fluid, such as cerebrospinal fluid.

公开(公告)号：WO2022237108A1

公开(公告)日：2022-11-17

申请号：PCT/CN2021/131042

申请日：2021-11-17

Applicant: 宁波市第一医院

Inventor： 程跃 ,  严泽军 ,  蒋军辉

IPC: A61M25/10 ,  A61M2025/006 ,  A61M2025/0073 ,  A61M25/0041 ,  A61M25/0043 ,  A61M25/007 ,  A61M25/0102 ,  A61M25/04 ,  A61M27/00 ,  A61M27/008

Abstract: 一种防堵肾造瘘管（71）和弯道引流肾造瘘管，其中，该防堵肾造瘘管（71）包括一管主体（710）、一标记线（790）和具有至少二引流槽（7200）以及一引流通道（7100），其中该管主体（710）包括一管前段（7103）和一管后段（7104），该引流通道（7100）贯通于该管后段（7104）并且位于该管后段（7104）内部，该管前段（7103）具有一侧表面（7105）并且该侧表面（7105）的至少部分凹陷地形成该引流槽（7200），每一个该引流槽（7200）被连通于该引流通道（7100），其中该引流槽（7200）具有一引流起始端（7201）和一引流末端（7202），该引流末端（7202）相对于该引流起始端（7201）被靠近于该管后段（7104）布置，并且相邻的该引流槽（7200）中的该引流起始端（7201）和该引流末端（7202）中的至少一个存在高度差，其中该标记线（790）被配置为可识别以凸显该管主体（710）的位置。

公开(公告)号：WO2022005713A1

公开(公告)日：2022-01-06

申请号：PCT/US2021/036522

申请日：2021-06-09

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： SCHERICH, Megan ,  BURKHOLZ, Jonathan, Karl ,  HARDING, Weston, F. ,  HOPWOOD, Benjamin ,  BLANCHARD, Curtis, H.

IPC: A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M2025/0004 ,  A61M25/0051 ,  A61M25/0067 ,  A61M25/007 ,  A61M25/0097 ,  A61M25/0113 ,  A61M25/0136 ,  A61M25/0606 ,  A61M25/09

Abstract: A catheter system (10) includes an outer catheter adapter (12), an outer catheter (18) having an outer catheter lumen (24) extending through the outer catheter, an inner catheter adapter (28), an inner catheter lumen (34) extending through the inner catheter adapter (28) and an inner catheter (36) extending distally from the inner catheter adapter (28) such that the inner catheter (36) is disposed within the outer catheter lumen (24), wherein the inner catheter (36) and the inner catheter adapter (28) are configured to move with respect to the outer catheter (18) and the outer catheter adapter (12) between a proximal position and a distal position.

公开(公告)号：WO2021222116A2

公开(公告)日：2021-11-04

申请号：PCT/US2021/029183

申请日：2021-04-26

Applicant: BARD ACCESS SYSTEMS, INC.

Inventor： HOWELL, Glade, H.

IPC: A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M25/09 ,  A61M2025/09116 ,  A61M25/0026 ,  A61M25/007 ,  A61M25/0097 ,  A61M25/0111 ,  A61M25/0606 ,  A61M25/0631 ,  A61M25/0693 ,  A61M25/09041

Abstract: Rapidly insertable central catheters ("RICCs") including catheter assemblies and methods thereof are disclosed. A RICC assembly (100) can include a RICC (102), an introducer (104), and a coupling system (106) configured to couple the RICC and the introducer together. A catheter tube (108) of the RICC can include a side aperture (114) in a distal-end portion of the catheter tube, which opens into an introducing lumen (118) extending from the side aperture to a distal end of the RICC. The introducer can include an introducer needle (128) having a cannula (138). The coupling system can include a distal coupler (146) slidably attached to the catheter tube proximal of the side aperture. The cannula extends through a longitudinal through hole of the distal coupler, through the side aperture of the catheter tube, along the introducing lumen of the catheter tube, and through the distal end of the RICC when the RICC assembly is in a ready-to- deploy state thereof.