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公开(公告)号：WO2020146523A1
公开(公告)日：2020-07-16
申请号：PCT/US2020/012777
申请日：2020-01-08
申请人： THE BRIGHAM AND WOMEN'S HOSPITAL, INC. , RIJKSUNIVERSITEIT GRONINGEN , CHENG, Tan-Yun , BUTER, Jeffrey
IPC分类号： A61K31/7016 , A61K39/395 , C07H3/04 , C07H11/04 , G01N33/569
摘要： Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6'-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.
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公开(公告)号：WO2020049016A1
公开(公告)日：2020-03-12
申请号：PCT/EP2019/073519
申请日：2019-09-04
发明人： CAO, Linqiu
IPC分类号： A23L33/21 , A23L33/00 , A61K31/702 , C07H3/04 , C07H3/06
摘要： The invention relates to the field of hypoallergenic oligosaccharides for use in nutritional compositions, in particular to oligosaccharides having prebiotic properties. Provided is a hypoallergenic oligosaccharide composition comprising galacto-oligosaccharides (GOS), wherein (i) the galacto-oligosaccharides (GOS) content is at least 40% by weight of the total dry matter of the composition; (ii) the allolactose content is at least 10% by weight of the total dry matter of the composition; (iii) the 6'-GL content is at least 30% by weight of the total GOS in the composition; and (iv) at least 0.5 % by weight of the total GOS has a polymerization degree (DP) of six or more. The GOS composition does not trigger GOS-allergy as assessed in a basophil activation test (BAT).
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公开(公告)号：WO2020024059A1
公开(公告)日：2020-02-06
申请号：PCT/CA2019/051058
申请日：2019-08-01
IPC分类号： G01N33/02 , A23L29/00 , A23L5/00 , A61K47/26 , A61K8/73 , C07H3/04 , C07H3/06 , C09D7/63 , C09D7/65 , C13K11/00 , D06M15/00
摘要： The present disclosure is directed to oligomolecular tags (OMTs) comprising hydrolyzed inulin oligosaccharides useful for tracing a product, as well as methods of producing OMTs. Also provided are methods of tracing a product comprising an OMT, and systems of tracing a product, wherein the systems comprise an OMT and a detector.
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公开(公告)号：WO2020003723A1
公开(公告)日：2020-01-02
申请号：PCT/JP2019/017474
申请日：2019-04-24
申请人： 日立化成株式会社 , 国立大学法人東北大学
IPC分类号： B01J21/18 , C07H1/00 , C07H3/02 , C07H3/04 , C07H3/06 , C08B1/00 , C08B15/08 , C13K1/02 , C13K13/00 , B09B3/00 , C07B61/00
摘要： バイオマス材料に含まれる多糖類を加水分解するための加水分解用触媒であって、昇温脱離法により５００℃～７００℃でＣＯを脱離する官能基を、フェノール性水酸基換算で０．４ｍｍｏｌ／ｇ以上で有する炭素材料である、加水分解用触媒である。
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公开(公告)号：WO2019172836A1
公开(公告)日：2019-09-12
申请号：PCT/SE2019/050211
申请日：2019-03-08
发明人： NILSSON, Kurt
摘要： A protein-binding product comprising one or more porous polymer beads, wherein at least one ligand is bound to the surfaces of said polymer beads via a spacer (R), and wherein said at least one ligand is Galβ1-3Hex NAcβ-O-, Galβ1-4Glc NAcβ-O- and/or a derivative thereof, is disclosed as well as a device containing said protein-binding product and a method for reduction of the level of at least one galactose-binding protein and optionally at least one other protein in human blood plasma.
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6.发明申请
公开(公告)号：WO2019169188A1
公开(公告)日：2019-09-06
申请号：PCT/US2019/020133
申请日：2019-02-28
IPC分类号： A61K31/7016 , A61K31/7028 , A61P37/04 , C07H3/04
摘要： The disclosure provides for therapies and methods to treat atherosclerosis and/or hyperlipidemia, and complications resulting therefrom, with compositions that comprise therapeutically effective amounts of one or more human milk oligosaccharides.
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7.发明申请
公开(公告)号：WO2019048997A1
公开(公告)日：2019-03-14
申请号：PCT/IB2018/056630
申请日：2018-08-30
申请人： BIOINNOTECH S.R.L.
摘要： The present invention relates to a process for the production of microbial biomass, in particular yeasts and milk bacteria, starting from whey and other waste of dairy industry. The process according to the present invention represents a valid alternative to the classical expensive disposal, having a high environmental impact, of dairy waste. At the same time, it provides an alternative method for the production of microbial biomass.
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公开(公告)号：WO2019040802A1
公开(公告)日：2019-02-28
申请号：PCT/US2018/047833
申请日：2018-08-23
申请人： BRAXTON, Olga, Elain
发明人： BRAXTON, Olga, Elain
CPC分类号： A23G1/40 , A23G1/00 , A23G1/30 , A23G1/32 , A23L27/30 , A23V2002/00 , A23V2200/3202 , A23V2250/614 , A23V2250/6414 , A23V2250/6418
摘要： A sweetened food product that functions to rehabilitate a person's indigenous gut bacteria comprises by percentage weight: 20-40% a composition of at least two bio-unavailable disaccharide sweeteners; 19-35% water soluble chocolate; 30-36% oil soluble chocolate; 0-5% sugar substitute; and 0-10% food grade emulsifier. The composition of at least two bio-unavailable disaccharide sweeteners may include the combination of mannitol and lactitol in substantially equal amounts, or the combination of lactulose and lactitol in substantially equal amounts.
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10.发明申请
公开(公告)号：WO2018102722A1
公开(公告)日：2018-06-07
申请号：PCT/US2017/064275
申请日：2017-12-01
发明人： CHANDRAN, Preethi
IPC分类号： A61K31/702 , A61K31/738 , C07H3/04
摘要： Methods and compositions are provided for preventing and/or treating infection by disrupting interactions at or near the surface of mannosylated pathogens or other pathogens exhibiting carbohydrate-carbohydrate self-interaction, thus enhancing the immune system's ability to recognize and destroy such pathogens. In some forms, carrier molecules are provided to delivering polymers or other molecules capable of disrupting intra-cellular interaction and/or self-interaction of surface markers on cells.
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