公开(公告)号：WO2021144211A1

公开(公告)日：2021-07-22

申请号：PCT/EP2021/050346

申请日：2021-01-11

Applicant: DANA, Jean Dominique

Inventor： DANA, Lou ,  JAZERON, Gildas

IPC: A61K8/02 ,  A61K8/66 ,  A61K38/43 ,  A61K38/44 ,  A61K38/46 ,  A61K38/47 ,  A61K38/54 ,  A61Q11/00 ,  A61K8/0216 ,  C12Y101/03004 ,  C12Y111/01007 ,  C12Y302/01003 ,  C12Y302/01026

Abstract: Un aspect de l’invention concerne un procédé de préparation d’une composition dentifrice, se présentant sous la forme d’une pastille comestible à sucer ou à mâcher et comportant : - Un complexe enzymatique comprenant les composés suivants : o invertase, o gluco oxydase, o amyloglucosidase, o lactoperoxydase, o lactoferrine, - au moins un agent gélifiant, caractérisé en ce qu’il comporte : - une étape de chauffage dudit au moins un agent gélifiant à une température comprise entre 82 et 88°C, - une étape d’encapsulation du complexe enzymatique par incorporation ou par ionisation dudit complexe enzymatique dans ledit au moins un agent gélifiant lorsque la température dudit au moins un agent gélifiant est comprise entre 55 et 65°C.

公开(公告)号：WO2020124128A1

公开(公告)日：2020-06-25

申请号：PCT/AU2019/051228

申请日：2019-11-08

Applicant: AGRICULTURE VICTORIA SERVICES PTY LTD

Inventor： VINCENT, Delphine Elsie Michelle ,  ROCHFORT, Simone Jane ,  SPANGENBERG, German Carlos

IPC: C07K14/415 ,  C07K1/36 ,  A61K38/54

Abstract: The present invention relates generally to a method for extracting cannabis-derived proteins from cannabis plant material, including the preparation of samples of extracted cannabis-derived proteins for proteomic analysis and methods for analysing a cannabis plant proteome.

公开(公告)号：WO2020086686A3

公开(公告)日：2020-04-30

申请号：PCT/US2019/057609

申请日：2019-10-23

Applicant: THE CHILDREN'S HOSPITAL OF PHILADELPHIA

Inventor： ARRUDA, Valder R. ,  SAMELSON-JONES, Ben

IPC: A61K38/14 ,  A61K38/16 ,  A61K38/37 ,  A61K38/54 ,  C12N15/63 ,  C07H21/04 ,  A61P7/04 ,  A61P7/08

Abstract: Factor VIII variants and methods of use thereof are disclosed.

公开(公告)号：WO2019067743A1

公开(公告)日：2019-04-04

申请号：PCT/US2018/053161

申请日：2018-09-27

Applicant: ABBVIE INC. ,  ABBOTT LABORATORIES GMBH ,  ABBOTT GMBH & CO. KG

Inventor： BABCOCK, Martin ,  BURNELL, Cynthia ,  KALTHOD, Vikram ,  BREITENBACH, Jörg ,  SCZESNY, Frithjof ,  RUEFFER, Frauke-Regina ,  SHLIEOUT, George

IPC: C12N9/94 ,  A61K38/46 ,  A61K38/54 ,  A61L2/08

Abstract: The present invention pertains to an enzyme preparation obtained from e-beam irradiated animal tissue, such as porcine pancreas. The present invention also pertains to methods for making such enzyme preparations, pharmaceutical compositions comprising such enzymes preparations, and methods for using such pharmaceutical compositions and enzyme preparations.

公开(公告)号：WO2019036336A1

公开(公告)日：2019-02-21

申请号：PCT/US2018/046442

申请日：2018-08-13

Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE

Inventor： NAGARAJ, Ram ,  LINETSKY, Mikhail ,  RAKETE, Stefan ,  NAHOMI, Rooban

IPC: A61K31/7088 ,  A61K38/54 ,  A61K45/06

Abstract: Compositions for the treatment and prevention of symptoms and disease conditions associated with oxidative and carbonyl stress, including advanced glycation end products (AGEs), and to methods using the compositions. In particular, the invention relates to compositions useful in the treatment of diabetic retinopathy and nephropathy, to compositions useful in the treatment of other retinal disorders including macular degeneration and cataracts.

公开(公告)号：WO2018170152A1

公开(公告)日：2018-09-20

申请号：PCT/US2018/022471

申请日：2018-03-14

Applicant: GEMINI THERAPEUTICS

Inventor： KAVANAGH, David ,  MARCHBANK, Kevin

IPC: A61K38/54 ,  A61K38/43 ,  C07K19/00

Abstract: The disclosure provides, in part, compositions comprising mature recombinant mature Complement Factor I (CFI) protein and methods of making and using those compositions.

公开(公告)号：WO2018128805A1

公开(公告)日：2018-07-12

申请号：PCT/US2017/067519

申请日：2017-12-20

Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

Inventor： MILLER, Laurence J.

IPC: A61K39/00 ,  A61K38/54 ,  A61K35/37 ,  A61K38/22 ,  A61K31/195 ,  A61K31/35

Abstract: This disclosure relates to methods and materials for treating functional dyspepsia (FD). Specifically, the disclosure provides a method for treating FD in a mammal, wherein said method comprising administering a composition comprising secretin, or a composition comprising neprilysin inhibitor, to a mammal identified as having FD, wherein a symptom of said FD is reduced. Further disclosed are symptoms of FD that can be treated.

公开(公告)号：WO2017172619A1

公开(公告)日：2017-10-05

申请号：PCT/US2017/024315

申请日：2017-03-27

Applicant: ABB VIE INC.

Inventor： BABCOCK, Martin ,  BURNELL, Cynthia ,  CRANDALL, Daniel ,  DETE, John ,  HESS, Mark ,  HERTZLER, Shannon ,  KALTHOD, Vikram ,  RIORDAN, William ,  SANDERS, Houston

IPC: A61K38/54 ,  A61L2/08 ,  C12N9/94 ,  A61P1/18

Abstract: The present invention pertains to an enzyme preparation obtained from e-beam irradiated animal tissue, such as porcine pancreas. The present invention also pertains to methods for making such enzyme preparations, pharmaceutical compositions comprising such enzymes preparations, and methods for using such pharmaceutical compositions and enzyme preparations.

Abstract translation: 本发明涉及从电子束照射的动物组织例如猪胰获得的酶制剂。 本发明还涉及制备这种酶制剂的方法，包含这种酶制剂的药物组合物，以及使用这种药物组合物和酶制剂的方法。

公开(公告)号：WO2016200916A1

公开(公告)日：2016-12-15

申请号：PCT/US2016/036419

申请日：2016-06-08

Applicant: ANSUN BIOPHARMA, INC.

Inventor： MOSS, Ronald D.

IPC: A61K38/54 ,  A61K38/46 ,  A61K9/50 ,  A61K38/00

CPC classification number: A61K38/47 ,  A61K9/0073 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/19 ,  A61K38/18 ,  A61K38/195 ,  A61K38/2053 ,  A61K38/55 ,  A61P31/14 ,  C07K2319/00 ,  C12Y302/01018 ,  Y02A50/471

Abstract: The present disclosure provides compositions and methods for treating an infection by human metapneumovirus (hMPV). In particular, the present disclosure provides methods that entail administering agents having an anchoring domain that anchors the compound to the surface of a target cell, and a sialidase domain that can act extracellularly to inhibit infection of a target cell by hMPV.

Abstract translation: 本公开提供了用于治疗人间质肺病毒（hMPV）的感染的组合物和方法。 特别地，本公开提供了使得具有将化合物锚定到靶细胞表面的锚定结构域的施用剂的方法，以及可以通过hMPV在细胞外作用以抑制靶细胞感染的唾液酸酶结构域。

公开(公告)号：WO2016055839A1

公开(公告)日：2016-04-14

申请号：PCT/IB2014/067226

申请日：2014-12-22

Applicant: UAB "BIOCENTRAS"

Inventor： GRIGISKIS, Saulius ,  CIPINYTE, Vilma ,  TVASKA, Bronislovas ,  URBANAVICIUTE, Ieva ,  RIMDEIKA, Rytis ,  MAURICAS, Mykolas

IPC: A61K38/46 ,  A61K38/54 ,  C12N9/14

CPC classification number: A61K38/54 ,  A61K8/66 ,  A61K8/99 ,  A61Q19/00 ,  A61Q19/007 ,  C12N9/00 ,  C12N9/14 ,  Y02A50/473

Abstract: This invention is attributed to the fields of biotechnology and biomedicine. The essence of this invention is to use enzymes extracted from Streptomyces gougerotii 101 in order to create multienzyme preparations with proteolytic, collagenasic, esterasic, amylolytic, lipasic, glucanasic, deoxyribunocleasic and lytic activities, and to employ them in the development of cosmetics, antibacterial preparations and preparations for wound care. Multienzyme biopreparation development technology is distinguishable by the fact that, as you change enzyme concentrations within, their application field changes too.

Abstract translation: 本发明归功于生物技术和生物医学领域。 本发明的实质是使用从链霉菌（Streptomyces gougerotii）101提取的酶，以产生具有蛋白水解，胶原，酯基，淀粉分解，脂肪酸，葡聚糖，脱氧核糖核酸和裂解活性的多酶制剂，并将其用于化妆品，抗菌制剂的开发 和伤口护理的准备。 多酶生物制剂开发技术的区别在于，当您改变酶浓度时，其应用领域也发生变化。