A three-dimensional memory device includes an alternating stack of insulating layers and electrically conductive layers located over a substrate, the alternating stack having a memory array region and a contact region containing stepped surfaces, and memory stack structures having a semiconductor channel and a memory film extending through the memory array region of the alternating stack. The electrically conductive layers include a drain select gate electrode and word lines, where the drain select gate electrode is thicker than each of the word lines.