- 专利标题: Efficient production of steviol glycosides in recombinant hosts
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申请号: US16002245申请日: 2018-06-07
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公开(公告)号: US11021727B2公开(公告)日: 2021-06-01
- 发明人: Ernesto Simon , Iben Nordmark Anderson , Michael Dalgaard Mikkelsen , Jorgen Hansen , Veronique Douchin
- 申请人: EVOLVA SA
- 申请人地址: CH Reinach
- 专利权人: EVOLVA SA
- 当前专利权人: EVOLVA SA
- 当前专利权人地址: CH Reinach
- 代理机构: McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号: C12P19/56
- IPC分类号: C12P19/56 ; C12N9/02 ; C12N9/88 ; C12N9/90 ; C07K14/395 ; C12N9/10 ; C12P15/00
摘要:
Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.
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