公开(公告)号：US11466302B2

公开(公告)日：2022-10-11

申请号：US16801200

申请日：2020-02-26

Applicant: EVOLVA SA

Inventor： Helene Lunde Robertsen ,  Iben Nordmark Andersen ,  Adam Matthew Takos ,  Swee Chuang Lim Hallwyl ,  Francesca Ambri ,  Manuel Quiros Asensio ,  Michael Dalgaard Mikkelsen ,  Jens Houghton-Larsen ,  Veronique Douchin ,  Jane Dannow Dyekjaer ,  Simon Carlsen ,  Nina Nicoline Rasmussen ,  Esben Halkjaer Hansen

IPC: C12P19/56 ,  A23L27/30 ,  C12N9/02 ,  C12N15/52 ,  C07H15/256 ,  C12N9/10 ,  C12N9/88 ,  C12N9/90

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US20220195477A1

公开(公告)日：2022-06-23

申请号：US17552355

申请日：2021-12-16

Applicant: EVOLVA SA

Inventor： Jane Dannow Dykejar ,  Jens HOUGHTON-LARSEN ,  Veronique Douchin

IPC: C12P19/56 ,  A23L27/30 ,  C12N15/52 ,  C12N9/10 ,  C07K14/395 ,  C12N15/82 ,  C12N15/81 ,  C12P15/00 ,  C12N9/90 ,  A23L2/60

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US20170369922A1

公开(公告)日：2017-12-28

申请号：US15541686

申请日：2016-01-29

Applicant: EVOLVA SA

Inventor： Kim Olsson ,  Ernesto Simon ,  Michael Dalgaard Mikkelsen ,  Simon Carlsen ,  Veronique Douchin ,  Swee Chuang Lim ,  Louis During

IPC: C12P19/56 ,  C12N9/10 ,  C07H15/256

CPC classification number: C12P19/56 ,  C07H15/256 ,  C12N9/1051 ,  C12P15/00 ,  C12Y204/01

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.

公开(公告)号：US20170218418A1

公开(公告)日：2017-08-03

申请号：US15328365

申请日：2015-08-07

Applicant: Evolva SA

Inventor： Veronique Douchin ,  Michael Dalgaard Mikkelsen ,  Iben Møller-Hansen

IPC: C12P19/44 ,  C12N1/16

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US12123042B2

公开(公告)日：2024-10-22

申请号：US17899069

申请日：2022-08-30

Applicant: EVOLVA SA

Inventor： Helene Lunde Robertsen ,  Iben Nordmark Andersen ,  Adam Matthew Takos ,  Swee Chuang Lim Hallwyl ,  Francesca Ambri ,  Manuel Quiros Asensio ,  Michael Dalgaard Mikkelsen ,  Jens Houghton-Larsen ,  Veronique Douchin ,  Jane Dannow Dyekjaer ,  Simon Carlsen ,  Nina Nicoline Rasmussen ,  Esben Halkjaer Hansen

IPC: C12P19/56 ,  A23L27/30 ,  C07H15/256 ,  C12N9/02 ,  C12N9/10 ,  C12N9/88 ,  C12N9/90 ,  C12N15/52

CPC classification number: C12P19/56 ,  A23L27/36 ,  C07H15/256 ,  C12N9/0042 ,  C12N9/0073 ,  C12N9/1085 ,  C12N9/88 ,  C12N9/90 ,  C12N15/52 ,  C12Y106/02004 ,  C12Y114/13078 ,  C12Y114/13079 ,  C12Y205/01029 ,  C12Y402/03019 ,  C12Y505/01013 ,  A23V2002/00 ,  C07K2319/00

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US11821015B2

公开(公告)日：2023-11-21

申请号：US17200673

申请日：2021-03-12

Applicant: EVOLVA SA

Inventor： Veronique Douchin ,  Swee Chuang Lim Hallwyl ,  Kim Olsson

IPC: C12N15/63 ,  C12P19/56 ,  A23L2/60 ,  A23L27/30 ,  G01N30/02

CPC classification number: C12P19/56 ,  A23L2/60 ,  A23L27/36 ,  C12N15/63 ,  G01N30/02 ,  G01N2030/027

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US20220017932A1

公开(公告)日：2022-01-20

申请号：US17244089

申请日：2021-04-29

Applicant: EVOLVA SA

Inventor： Ernesto Simon ,  Iben Nordmark Anderson ,  Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Veronique Douchin

IPC: C12P19/56 ,  C12N9/02 ,  C12N9/88 ,  C12N9/90 ,  C07K14/395 ,  C12N9/10 ,  C12P15/00

Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretion of steviol glycosides of interest.

公开(公告)号：US20200291442A1

公开(公告)日：2020-09-17

申请号：US16754247

申请日：2018-12-05

Applicant: EVOLVA SA

Inventor： Veronique Douchin ,  Swee Chuang Lim Hallwyl

IPC: C12P19/56 ,  C12N1/18 ,  C12N1/16

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US20190144907A1

公开(公告)日：2019-05-16

申请号：US16098305

申请日：2017-05-16

Applicant: Evolva SA

Inventor： Iver Klavs Riishede Hansen ,  Veronique Douchin ,  Jens Houghton-Larsen ,  Esben Halkjaer Hansen ,  Angelika Semmler ,  Laura Occhipinti ,  Kim Olsson

IPC: C12P19/56 ,  C12N15/70 ,  C12N15/81

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosides of steviol precursors, and steviol glycoside precursors.

公开(公告)号：US20180371517A1

公开(公告)日：2018-12-27

申请号：US16002245

申请日：2018-06-07

Applicant: EVOLVA SA

Inventor： Ernesto Simon ,  Iben Nordmark Anderson ,  Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Veronique Douchin

IPC: C12P19/56 ,  C07K14/395 ,  C12N9/10 ,  C12N9/90 ,  C12N9/88 ,  C12N9/02 ,  C12P15/00

Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.