公开(公告)号：US20230374558A1

公开(公告)日：2023-11-23

申请号：US18350982

申请日：2023-07-12

申请人： AJINOMOTO CO., INC. ,  EVOLVA SA

发明人： Howard RIEZMAN ,  Sabina de Andrade Pereira TAVARES ,  Markus SCHWAB ,  Vsevolod Aleksandrovich SEREBRIANYI ,  Olga Aleksandrovna SOFYANOVICH ,  Anna Mikhailovna OZEROVA ,  Naoki IWANAGA

IPC分类号： C12P13/02 ,  C12P19/44 ,  C12N9/16 ,  C12N15/81

CPC分类号： C12P13/02 ,  C12P19/44 ,  C12N9/16 ,  C12Y301/03004 ,  C12N15/81 ,  C12N2800/102

摘要： A method for producing an objective substance such as phytosphingosine (PHS) and phytoceramide (PHC) using yeast is provided. The objective substance is produced by cultivating yeast having an ability to produce the objective substance and modified so that the expression and/or activity of a protein(s) encoded by NEM1 and/or SPO7 gene(s) is reduced in a culture medium.

公开(公告)号：US11800867B2

公开(公告)日：2023-10-31

申请号：US17525074

申请日：2021-11-12

申请人： EVOLVA SA

发明人： Jean Davin Amick ,  Bryan N. Julien ,  Kim Thu Le Greenbaum

IPC分类号： A01N35/06

CPC分类号： A01N35/06

摘要： The invention relates to biting arthropod repellent compositions comprising nootkatone. The application also relates to a method of repelling said biting arthropods by application of the nootkatone composition to a hard or soft surface, to a method of treating an arthropod infestation and to a method of reducing the transmission of a parasite or disease pathogen spread by a biting arthropod using the nootkatone composition.

公开(公告)号：US11466302B2

公开(公告)日：2022-10-11

申请号：US16801200

申请日：2020-02-26

申请人： EVOLVA SA

发明人： Helene Lunde Robertsen ,  Iben Nordmark Andersen ,  Adam Matthew Takos ,  Swee Chuang Lim Hallwyl ,  Francesca Ambri ,  Manuel Quiros Asensio ,  Michael Dalgaard Mikkelsen ,  Jens Houghton-Larsen ,  Veronique Douchin ,  Jane Dannow Dyekjaer ,  Simon Carlsen ,  Nina Nicoline Rasmussen ,  Esben Halkjaer Hansen

IPC分类号： C12P19/56 ,  A23L27/30 ,  C12N9/02 ,  C12N15/52 ,  C07H15/256 ,  C12N9/10 ,  C12N9/88 ,  C12N9/90

摘要： The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US20220195477A1

公开(公告)日：2022-06-23

申请号：US17552355

申请日：2021-12-16

申请人： EVOLVA SA

发明人： Jane Dannow Dykejar ,  Jens HOUGHTON-LARSEN ,  Veronique Douchin

IPC分类号： C12P19/56 ,  A23L27/30 ,  C12N15/52 ,  C12N9/10 ,  C07K14/395 ,  C12N15/82 ,  C12N15/81 ,  C12P15/00 ,  C12N9/90 ,  A23L2/60

摘要： The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US11299717B2

公开(公告)日：2022-04-12

申请号：US16338186

申请日：2017-10-11

申请人： Evolva SA ,  Takasago International Corporation

发明人： Thomas Oestergaard Tange ,  Johannes Haerle ,  Fanny Delegrange ,  Julien Denis Vivian De Block ,  Robert Charles Allan ,  Philipp Friedrich Berninger ,  Christophe Folly ,  Davide Antonio Ravasio ,  Ludivine Labagnere ,  Federico Brianza ,  Curt Aimé Friis Nielsen ,  Jørgen Hansen ,  Nora Weber ,  Samantha Jessica Capewell

IPC分类号： C12P7/00 ,  C12N9/02 ,  C12N9/04 ,  C12N9/10 ,  C12N9/16 ,  C12N15/52 ,  C12P7/24 ,  C12P7/40 ,  C12N9/00 ,  C12P5/00 ,  C12P7/04

摘要： The invention relates to recombinant microorganisms and methods of producing citronellal, citronellol, citronellic acid, and/or citronellal/citronellol pathway intermediates and precursors.

公开(公告)号：US11248248B2

公开(公告)日：2022-02-15

申请号：US16618880

申请日：2018-06-15

申请人： EVOLVA SA

发明人： Jens Houghton-Larsen

IPC分类号： C12P33/20 ,  A23L27/30 ,  A23L2/385 ,  A23L2/60 ,  B01D9/00 ,  B01D11/04 ,  B01D15/32 ,  B01D15/36 ,  C12N1/16 ,  C12N9/42 ,  C12N15/81 ,  C12N9/24 ,  C12P19/56

摘要： The invention relates to recombinant microorganisms and methods for producing mogroside compounds and mogroside precursors.

公开(公告)号：US11155841B2

公开(公告)日：2021-10-26

申请号：US15898358

申请日：2018-02-16

申请人： AJINOMOTO CO., INC. ,  EVOLVA SA

发明人： Markus Schwab ,  Corina Daniela Wirdnam ,  Thomas Oestergaard Tange ,  Maud Babau ,  Anaelle Hatsch ,  Fanny Delegrange ,  David Fischer ,  Sabina de Andrade Pereira Tavares

IPC分类号： C12P13/00 ,  C12P13/02

摘要： A method for producing an objective substance such as sphingoid bases and sphingolipids using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture medium containing an additive that is able to associate with, bind to, solubilize, and/or capture the objective substance, and collecting the objective substance from cells of the yeast and/or the culture medium.

公开(公告)号：US10294499B2

公开(公告)日：2019-05-21

申请号：US15575481

申请日：2016-05-27

申请人： EVOLVA SA

发明人： Ernesto Simon Vecilla ,  Beata Joanna Lehka ,  Carlos Casado Vazquez

IPC分类号： C12P7/42 ,  C12N9/88 ,  C12P7/22 ,  C12N1/16 ,  C12N1/20 ,  C12P13/22

摘要： Provided herein are recombinant hosts and methods for producing phenylpropanoid and phenylpropanoid derivative compounds. It was found that tyrosine ammonia lyase from Aeromonas salmonicida A449 provides improved coumaric acid production.

公开(公告)号：US09957540B2

公开(公告)日：2018-05-01

申请号：US14761629

申请日：2014-02-06

申请人： Evolva SA

发明人： Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Ernesto Simon ,  Federico Brianza ,  Angelika Semmler ,  Kim Olsson ,  Simon Carlsen ,  Louis Düring ,  Alexei Ouspenski ,  Paula Hicks

IPC分类号： C12P19/56 ,  A23L2/60 ,  C12N9/02 ,  C12N9/10 ,  C12N9/90 ,  C12N15/81 ,  A23L27/30

CPC分类号： C12P19/56 ,  A23L2/60 ,  A23L27/36 ,  A23V2002/00 ,  C12N9/0071 ,  C12N9/1051 ,  C12N9/1081 ,  C12N9/1085 ,  C12N9/90 ,  C12N15/81 ,  C12Y204/01 ,  C12Y204/99

摘要： Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided herein.

公开(公告)号：US09920349B2

公开(公告)日：2018-03-20

申请号：US14356782

申请日：2012-11-19

申请人： Evolva SA

发明人： Yaoquan Liu ,  Jung Yeop Lee ,  Monika Khare

IPC分类号： C12P33/20 ,  C12P19/18 ,  C12P33/00

CPC分类号： C12P33/20 ,  C12P19/18 ,  C12P33/00

摘要： Methods and materials for enzymatic synthesis of mogroside compounds described.